Garra rufa (doctor fish): 141293385
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Entry
141293385 CDS
T11039
Symbol
pik3ca
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
grf Garra rufa (doctor fish)
Pathway
grf00562
Inositol phosphate metabolism
grf01100
Metabolic pathways
grf04012
ErbB signaling pathway
grf04068
FoxO signaling pathway
grf04070
Phosphatidylinositol signaling system
grf04081
Hormone signaling
grf04140
Autophagy - animal
grf04150
mTOR signaling pathway
grf04210
Apoptosis
grf04218
Cellular senescence
grf04370
VEGF signaling pathway
grf04510
Focal adhesion
grf04517
IgSF CAM signaling
grf04518
Integrin signaling
grf04620
Toll-like receptor signaling pathway
grf04625
C-type lectin receptor signaling pathway
grf04810
Regulation of actin cytoskeleton
grf04910
Insulin signaling pathway
grf04914
Progesterone-mediated oocyte maturation
grf05100
Bacterial invasion of epithelial cells
grf05132
Salmonella infection
grf05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
grf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
141293385 (pik3ca)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
141293385 (pik3ca)
04370 VEGF signaling pathway
141293385 (pik3ca)
04068 FoxO signaling pathway
141293385 (pik3ca)
04070 Phosphatidylinositol signaling system
141293385 (pik3ca)
04150 mTOR signaling pathway
141293385 (pik3ca)
09133 Signaling molecules and interaction
04081 Hormone signaling
141293385 (pik3ca)
04517 IgSF CAM signaling
141293385 (pik3ca)
04518 Integrin signaling
141293385 (pik3ca)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
141293385 (pik3ca)
09143 Cell growth and death
04210 Apoptosis
141293385 (pik3ca)
04218 Cellular senescence
141293385 (pik3ca)
09144 Cellular community - eukaryotes
04510 Focal adhesion
141293385 (pik3ca)
09142 Cell motility
04810 Regulation of actin cytoskeleton
141293385 (pik3ca)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
141293385 (pik3ca)
04625 C-type lectin receptor signaling pathway
141293385 (pik3ca)
09152 Endocrine system
04910 Insulin signaling pathway
141293385 (pik3ca)
04914 Progesterone-mediated oocyte maturation
141293385 (pik3ca)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
141293385 (pik3ca)
09171 Infectious disease: bacterial
05132 Salmonella infection
141293385 (pik3ca)
05100 Bacterial invasion of epithelial cells
141293385 (pik3ca)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
grf04131
]
141293385 (pik3ca)
Enzymes [BR:
grf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
141293385 (pik3ca)
Membrane trafficking [BR:
grf04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
141293385 (pik3ca)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_C2
PI3K_rbd
PI3K_p85B
DUF2321
ABC1
Ribosomal_S15
Motif
Other DBs
NCBI-GeneID:
141293385
NCBI-ProteinID:
XP_073681515
LinkDB
All DBs
Position
20:10511023..10535167
Genome browser
AA seq
1069 aa
AA seq
DB search
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGAHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTEADIEQLRQLANRDPL
SEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSTTLHQWLKDKNKGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
NT seq
3210 nt
NT seq
+upstream
nt +downstream
nt
atgcctccaagaccctcttcgggagaactatggggcatccatttgatgccccccaggatt
ctggtggactgtctactgcccaatggcatgatcctgacactagaatgcctccgggaggcc
accctcatcacaatcaaacatgaactgtttaaggaggctaggaagtaccccctccaccac
ctgctgcaggaggagacctcctatattttcgttagtgtaacacaagaggcagagcgtgag
gagttctacgatgagacaagaagactttgtgaccttcggctgttccagcccttcctaaag
gtcatagaacctgtagggaacagagaggaaaaaatcctcaacagagaaattggttttgcc
atcggcatgccggtgtgtgagtttgatctagtgaaggaccctgaggtgcaggacttcagg
agaaatattcttaatgtctgcaaagactcagtagagctacgagatgccagcggggcacac
agtcgagcgctatacgtttatcctcctaatgtggagtcttcaccagagcttccaaagcat
atatatggcaaattagacaaaggtcaaatcattgtagttatctgggtgatcgtctctccc
aacaacgacaagcaaaagtacacactaaagatcaatcacgactgcgtacctgagcaggtg
atcgctgaagccatcaggaagaagactaggagcatgctgctgtcggccgagcagctaaag
atgtgcgtgcaagaatatcagggcaaatacatcctgaaagtctgcggctgtgacgagtat
ctgttggaaaaataccctatcagtcagtacaagtatgtacggagttgcattatgctgggt
cggttgccaaacctcatgcttatgtccaaggacagtctttactctcagctgcctatggac
aacttcaccatgccctcctacgcccgccggatctccaccgccacgccttacatgaacgga
gaggcttccaccaaatccctctggaccattaacagcactctaaggatacgtgtcctctgt
gccacatacgttaatgtgaatattcgggacattgacaagatttatgtgcggacagggatc
taccatggtggagagcagttgtgtgataatgtcaacacacagcgtgtgccgtgttcaaac
ccaaggtggaacgagtggctgacttatgacatgtacattcccgacatcccccgggcggct
cgcctttgtctgtccatctgctctgtgaaaggaaggaagggggcgaaagaggagcactgt
ccactggcctggggaaacgtcaacctgttcgactacacacacactctggtctcaggaaag
atggcactgaacctgtggccagtaccacatggcctagaagatctcctcaaccccattggg
gtcacgggctccaaccctaataaggaaaccccatgtctagagctggagtttgaccatttc
agctcacccgttaagttccctgacatggccacgattgaggatcacgctaactggataata
tccagggagatgggatacaattactgccagtctggacagagcagcagactggcgcgagac
cacgccatgacggaggcagatatagagcaacttcgtcagctggccaacagggacccgctt
tctgaaatcactgagcaggaaaaagactttttatggagacacaggcagtattgtgtaaat
attccagaaatcctgcccaagattctgctggcggtgaaatggaattccagggatgaagtt
gcccagatgtattgccttcttaaagactggcctgcaataaagccggaacaagccatggag
ttgcttgactgtaactatcctgatccaatgatccgagacttcgcagttcggtgccttgag
aagtatctgactgatgacaaactctcacagtacctcattcagctagttcaggttttgaag
tatgagcagtatcttgataacccactggtgcgatttctgctgaaaaaagctcttaccaac
cagaggattgggcacttcttcttttggcatttgaagtcagaaatgcacaataaaaccgtg
agtcagcggtttggcctgctgctggagtcgtactgccgggcatgtggcatgtacctgaag
cacctgagcagacaggtggaagccatggagaagctcatcaacctcacagacattctcaaa
caggagaagaaggatgaaactcagaaggtgcaaatgaagttcttggtggagcagatgagg
cgaccggactacatggatgccctccaaaatttcacctctccactcaaccccgcccaccag
ctgggtaacctacgacttgaagactgcagaatcatgtcatctgccaagagaccgctctgg
ttgaactgggaaaatcctgacatcatgtccgaactcctcttccaaaacaatgagatcatc
ttcaagaacggagatgacctgcggcaagacatgctaacactacagatcatcagaataatg
gagaacatttggcaaaatcagggtctggatctgagaatgctaccctatggctgcttgtct
attggagactgcgtgggtctcatcgaagtggtgagaagttcccacaccatcatgcagatt
caatgtaaaggaggtctaaagggggcactgcagtttaacagtacaacactgcatcagtgg
ctaaaagacaagaacaaaggagagatgtacgacatggccatcgacttgtttacacgatcc
tgcgctggctattgtgtggcgacgttcattctgggcatcggtgacagacacaacagtaac
atcatggtgaaggatgacgggcagctgtttcatatagatttcggtcactttttggaccac
aagaagaagaagtttggctacaagcgcgagcgagtgccgttcgtcttgactcaagacttt
ttaattgtgatcagcaaaggaggaacccaagagtgcactaaaaccagagagtttgagagg
ttccaggagatgtgctacaaggcttacttggctatcagacagcatgccaaccttttcata
aatctcttctccatgatgctgggctcaggcatgccagagttgcagtccttcgacgacatc
gcttacatccgaaagaccctggcgctggacaaaacagagcaggaggccctggactatttc
atgaagcagatgaatgacgctcaccatggtggatggaccaccaagatggactggatcttt
cacaccatccgacaccatgcccaaaactga
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