Garra rufa (doctor fish): 141297576
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Entry
141297576 CDS
T11039
Symbol
top2a
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
grf Garra rufa (doctor fish)
Brite
KEGG Orthology (KO) [BR:
grf00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
grf03032
]
141297576 (top2a)
03036 Chromosome and associated proteins [BR:
grf03036
]
141297576 (top2a)
Enzymes [BR:
grf01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
141297576 (top2a)
DNA replication proteins [BR:
grf03032
]
Eukaryotic type
DNA Topoisomerases
141297576 (top2a)
Chromosome and associated proteins [BR:
grf03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
141297576 (top2a)
Centrosome formation proteins
Centriole proteins
141297576 (top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Motif
Other DBs
NCBI-GeneID:
141297576
NCBI-ProteinID:
XP_073684090
LinkDB
All DBs
Position
22:11461938..11494753
Genome browser
AA seq
1573 aa
AA seq
DB search
MAGTEGPLKSLFENKPLSKTKKDPKRLSVERIYQKKTQLEHILLRPDTYIGSVEPVTQQM
WVFDEDVGMNCRDITFVPGLYKIFDEILVNAADNKQRDKTMNCIKVNIDSENNAISVWNN
GKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVET
ACRESKQSFKQTWFDNMGRAGECKIKPFDGDDYTCITFQPDLAKFKMEALNKDTVALLTR
RAYDIAGSTKGVRVFLNGKKLAVKDFRSYVDLYLKDKVDETGSPLTIVHESTNERWEVCL
TLSEKGFQQVSFVNSIATTKGGRHTDYVADQIVSKLIEVVKKKNKAGVAVKPFQVKNHMW
LFVNCLIENPSFDSQTKENMTLQQKNFGSTCSLSDKFVKQANSCGIVESIMNWVKFKAQA
QLNKKCSAVKHTKIKGVPKLDDANDAGGKNSTSCTLILTEGDSAKTLAVSGLGVVGRDRY
GVFPLRGKMLNVREASHKQIMENAEINNIIKILGLQYRKNYSDPESLKSLRYGKLMIMTD
QDQDGSHIKGLLINFIHHNWPSLLHHNFLEEFITPIIKASNKKQELSFYSIPEFNEWKDK
QSSLKSWKIKYYKGLGTSTSKEAKEYFSDMTRHRIPFKYSGPADDEAITLAFSKKMVDER
KEWLTSFMINRRQRREHNLPEEYLYGQTTTSLTYHDFINKELVLFSNSDNERSIPCLVDG
LKPGQRKVLFCCFKRNDKREVKVAQLAGSVAEMSAYHHGEVSLMMTIVGLAQNFVGSNNL
NLLQPLGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPAVDDNLLKYNYDDNLRVEPEWY
IPIIPLVLANGGEGIGTGWASRIPNYDLREIINNIHRLLNGEEALPMLPSYKGFKGTMDE
LAKNQYVNNGEVAIIDSTTIEITELPIKTWTQAYKENVLEAMLNGTDKVPPLITDYKEYH
TDTTVRFVIKMTEERLREAEAAGLHKVFKLQNLLTCHSMVLFDHVGSLMKYESVQDILKD
FFELRMKYYVLRKDWLLGMLGAESTKLSNQARFILEKIQGTLVIENKPKKELIRMLQEMG
YDSDPVKAWKDAQEKDAEEDAGEDDEEKEKEDTSGPDYNYLLSMPMWFLTKEKKEELCRQ
RDAKMTELNTLKMKAPADLWKEDLAAFTEELERLEQKELESQNAVPVVKGKVGRSKVVKV
KNETMPTPQGRRVIPRITSTMKVQAVKKEGAKKGKAGKKEAGVVMKMEFDEADTAADGTE
MGLAARLAKKIKKEPAKGRSSKSGKQTTLSFKPVQKKHSMSSEEELSESDVEMVIPEEVA
PREKRGRKAAAEKKYSLSSSEDEFDDWPKSTKQKRAVIDDDDDDDSFNPEPSGAPDSDMD
SPPPAPVVKKAPAKASKPKVEKPEASSKSDSNSETSQEPAPKPVKKTAEGATKKPAAKKT
SAAAKKKATDAKQPSILDVLSKKSPKTTKATKKPAALKLSSDSDSAAPAVVEKKPAKKRK
PALSSDQSDSSDSDSGNLMARLKGKSTAGKKAKSWDDDDSFHLEEKIVTSAAPRSRVART
AKPVTYTLDSDSD
NT seq
4722 nt
NT seq
+upstream
nt +downstream
nt
atggctggaacagaaggacctctgaagagtttgtttgagaataagcctctcagtaagacc
aagaaagatccgaaacgtctgtctgtggaaaggatctatcagaagaagacccagctggag
catatcctgctccggcccgacacctacataggctctgtggagcctgtaactcagcaaatg
tgggtgtttgatgaggatgttggcatgaactgcagagatatcacatttgtgccaggactc
tacaagatctttgatgagattctggtgaatgctgctgataacaaacagagggacaaaact
atgaactgcatcaaggtcaacattgactcggagaataatgccatcagtgtgtggaacaac
gggaagggtattcctgtggttgagcacaaggtggaaaaggtgtatgttcctgctctgatt
ttcggccaactcctgacctccagtaactatgatgatgatgagaagaaggtcacaggtggc
cgtaatggatacggtgcgaagctgtgtaacatcttcagcaccaagttcactgtggagacg
gcctgccgagagtcaaagcaaagtttcaaacagacatggtttgataacatgggccgagca
ggcgagtgtaaaatcaaaccctttgatggcgatgactatacctgcatcacgttccagccg
gacctggcaaaatttaagatggaggctttaaataaagacactgttgcactgctgactcga
cgtgcatatgacattgctgggtccactaagggtgtccgtgtctttctcaacggcaagaag
ctggcagttaaggatttccgaagctatgttgacctgtatctaaaggataaggtggacgag
actggttctcccctgacaatagttcacgagtctacgaatgagcgctgggaggtgtgtctt
acccttagtgaaaaagggttccaacaagtcagctttgtaaacagcatcgccacgactaag
ggtggcagacacactgactatgttgcagaccagattgtgtccaaactgattgaagttgtg
aagaagaaaaacaaggctggtgtggccgtcaaacctttccaggtgaagaaccacatgtgg
ttgtttgtgaactgtctgattgagaaccccagctttgactctcagaccaaagagaacatg
accttgcaacagaagaatttcggttccacctgctctctgagtgacaagttcgttaaacag
gctaatagctgtggaattgtggagagcataatgaactgggtgaagtttaaagcccaggct
cagctcaataagaaatgctctgctgtcaaacacaccaagattaagggagtgcccaagttg
gatgacgccaacgatgcaggtgggaagaactccactagctgcactctgatcctgacagaa
ggagactcggccaaaactctggccgtgtctggtctgggggtggtgggacgtgatcgctat
ggtgtcttccctctgcgtggtaaaatgctcaacgttcgagaggcatcgcacaagcagatc
atggagaatgctgagatcaataacatcataaagatccttggtctgcagtacagaaagaac
tacagtgacccagagtcactcaagagtttgcgctatggcaagctcatgatcatgacagat
caggatcaagacggatctcacattaaaggtcttctcatcaacttcatccatcataactgg
ccgtctctgctgcaccacaacttcctagaagagttcatcactcctatcatcaaggcatcc
aataagaagcaggagctttctttctacagtatcccagagttcaatgagtggaaggacaaa
caaagtagcctcaaatcctggaagatcaaatactacaaaggtttgggtaccagcacatct
aaggaggccaaagagtatttttcagatatgacaagacatcgaattccttttaagtactct
gggcccgcagatgatgaagctatcaccctggcctttagcaagaagatggtagatgagagg
aaggaatggctgaccagcttcatgatcaacagacgtcagcgcagagaacacaacctgcct
gaggagtacctatatggacaaacaacgacctccctcacctaccacgactttatcaataaa
gagcttgttctgttctccaactctgacaacgagagatcaatcccctgcttggtggatggg
ctaaaaccaggccaaaggaaagtgcttttctgctgtttcaagaggaatgataagagagag
gtgaaagtggctcagttggctggatcagtggctgagatgtcagcataccaccatggagag
gtctctctcatgatgaccattgtgggtcttgctcagaactttgtgggcagtaataatttg
aacctgcttcagcctctgggtcagtttggcacacgtctgcatggaggcaaagactctgcc
agccccagatacatctttaccatgcttagtccacttgctcgtctgctgttccctgctgtg
gacgataacctgttgaagtacaattacgatgataatttgcgagtggagccagagtggtac
atacctatcatccctctggtgctggctaatggaggtgagggcatcggcacaggatgggcc
agccgcattcccaactatgacttgcgagagatcattaacaatattcaccgcttgctcaat
ggcgaagaggcacttcccatgctgcccagctataaggggttcaaaggcaccatggacgaa
ctggcaaagaatcagtatgtgaataatggagaggtggccatcattgactctaccaccatt
gagatcactgagctgccaatcaaaacctggacacaggcctataaggagaatgtgttggag
gcgatgctgaacggcacagacaaggttcctcctttgatcacagactataaggagtatcat
acagacaccacagtgcgtttcgtcattaagatgacagaggagcgcctgagagaggctgag
gcagctggacttcacaaagtcttcaaactacaaaatctgctcacctgtcactccatggta
ttgtttgatcatgtgggcagtctgatgaagtacgagtctgttcaggacatcttgaaggat
ttctttgagctcagaatgaagtattacgtcctcaggaaagactggctgctaggtatgctg
ggagctgaaagcaccaaactttccaaccaggcccgattcattctggagaagatccagggc
acgctggtcattgaaaataaacctaagaaggagctgatccgcatgcttcaggagatgggc
tatgactcggaccctgttaaggcatggaaagatgctcaggagaaggatgcagaggaggat
gctggggaggatgatgaggagaaggaaaaagaggacacatctggtcctgattataactat
ctgctcagcatgcccatgtggttcctgaccaaagaaaagaaagaagagctgtgcagacag
agagatgctaagatgacagagttgaacacgctcaagatgaaagcgcctgctgatctgtgg
aaagaggatctggcagcctttactgaagagctggagcgtttggaacagaaggagttagag
tcacagaatgcagtgcctgtggtgaaaggtaaagtgggcagatcaaaggtggtgaaggta
aagaacgagaccatgcccaccccacagggccgccgcgtcattccccgcatcaccagcacc
atgaaggtccaggctgttaagaaggagggagccaaaaaaggcaaagctgggaagaaagag
gctggtgtggtgatgaagatggagtttgatgaggcagacacagcagctgatggcactgag
atgggactggctgcaagacttgctaagaagatcaaaaaagagccggctaaaggcagaagc
tcaaaatcaggaaagcagaccaccctctcctttaaaccagtccagaagaagcactccatg
tcttctgaggaggaattgtctgaatctgacgttgagatggttatccctgaggaagtggct
ccaagagagaagagagggcgcaaagctgcagctgaaaagaagtacagtctgtcaagcagt
gaagatgagtttgatgactggccgaaaagcactaaacaaaagcgtgccgtcattgatgat
gatgatgatgatgattccttcaacccagaacccagcggtgcacctgatagtgacatggat
tcccctcctcctgcacctgttgtgaaaaaggcaccagcgaaagccagcaaaccaaaagta
gagaaacctgaagctagcagcaagtctgactctaattctgagaccagccaagagccggcc
cctaaaccagtgaagaaaacagctgaaggagccaccaagaaacctgccgcaaaaaagaca
agtgctgctgcaaagaagaaagcaacagatgcaaaacagccctcaatccttgatgtgctc
tccaagaaaagccctaaaacaaccaaagccaccaagaagcctgctgctctcaaactgtct
tctgactcggatagcgcagcccctgctgtggttgagaagaaaccagccaaaaagaggaag
cccgctctgagcagtgaccagtcagacagctcagactctgacagtggcaatctcatggct
cgcctcaagggcaaaagcactgctggaaagaaagcaaagagctgggatgacgatgacagc
tttcacctggaagagaagatagtgacatctgcagctccgagaagccgagttgcacgtact
gccaaacctgtgacctatactcttgattcagattctgattaa
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