Garra rufa (doctor fish): 141301508
Help
Entry
141301508 CDS
T11039
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
grf Garra rufa (doctor fish)
Brite
KEGG Orthology (KO) [BR:
grf00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
grf01001
]
141301508 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
grf04131
]
141301508 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
grf04147
]
141301508 (lrrk2)
Enzymes [BR:
grf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
141301508 (lrrk2)
Protein kinases [BR:
grf01001
]
Serine/threonine kinases: TKL group
LRRK family
141301508 (lrrk2)
Membrane trafficking [BR:
grf04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
141301508 (lrrk2)
Exosome [BR:
grf04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
141301508 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_4
LRR_8
Roc
COR-A
Ras
LRR_14
COR-B
Beta-prop_WDR3_2nd
Beta-prop_WDR36-Utp21_1st
LRR_13
Beta-prop_RSE1_2nd
WD40_CDC20-Fz
WDR55
Beta-prop_EML_2
Ank
Ank_3
NBCH_WD40
ZER1-like_2nd
Beta-prop_WDR3_1st
Ank_2
Kdo
Beta-prop_WDR5
Beta-prop_HPS5
LRR_NXF1-5
Arf
Motif
Other DBs
NCBI-GeneID:
141301508
NCBI-ProteinID:
XP_073687803
LinkDB
All DBs
Position
25:36476581..36527645
Genome browser
AA seq
2535 aa
AA seq
DB search
MADKEELGIRLKKLLVRLNLQEGKQLGTIVQIIQDLLFLSHTDHCVELFADQSVHMPLML
VLSSHFNSKVQQVGWSLLCRLMEICPATLDSLACPVEYEFTEVHKQILKVLTMYAKDSKM
MMVGLRALALLLKSGEIVMRVLYEKEDDVFFLILEAMRSFDDKEEVQLQGCAALQLLLQR
ISDAHLLEFIENKDHEVILNALRRFMDSENVVLQALRVLIPLAAPASNIEILMSKPVKCY
SLLCQAMDMWLDSEAIQVAGCCLLRKFTSESYHNILVLNGVHKVAVKACVSYPENATLQT
EAFSCLSALLECIVQNEGLGKEWNEEDGGKQKVLVKKEATQAEEMLIWREACYTALERHA
DDAAVQEAACWALNSLLLHCNSSNHVELEGRPPLHSLVMAAMLLHSSSVGVFQAASCTLH
TLIERHSRMRAQLLSHGIHVNIVVLMQKHESSSAVCESACKLLHILFQGPRASLDDATLI
LGQILTALKTHNFIPEVQLEGLRASLVLLNPDRSLREHGASVADPDTVDVSLRVLKNQCV
LEGAHAVYLQALNRFISSEEIQECGLGLLSTLADSSGAVDLMCQQGAIDTVLHTLQMFPQ
GRDVHYWGLSLLFHLISKKKLSCMMVPVLASVLVSSIRQHRDDTVMLLKGFQAVLKLLDT
CSSAAAWLQKEAFEKDIFQILREKTADARLDRLQGRSCLCLSKMVADSEIMYALLERACE
EGDVDMAECLIQLGADINKKTKSDSLIYQICDRGSPLALLELLVSAGVHEQQLRGALSVC
IRRGDDPAITLLLARLGLDHANNALCLGSFRLGQMKAAWLNALLSERKTQSPVSKKNNKG
QRLARQILSLQRNKSFVGVSRLRSDASTSEYFTDEESDDSHMSLDESLALVFDDMESDGS
DGPSQGSLLFGDSPEVGRKPAWRHRSLRRRANSEGGHGDTDPSVPRHKRFNSHNTRGQGF
TESSTPGAFPLAVDKEPIRLLDLSGNELGNLSCLMGVSSLKQQIENLLRLDLSSNSLSEF
PSVLCQNLRSLTRLDLQGNQLQSLPVELLGLPALSTLNVSRNCIGPLLLLDPTVRSPALR
QLNLSFNQLTVFPFQLGQAMDRLEELSLEGNQISALSLPLCLPELKVLDISKNQVNNISD
NFLTECLKLETFNASVNQISSLSHLPSKITTVKLSQNNFTSIPEIIINLPNLRSVDMRNN
SISDLPGPSFWVSVNLRELMFSHNQISVLDLSGPTYKWARLEKLTLSSNKLTEIPPQIGM
LEDLTSLDVSQNQGLRSFPDEMGKLVHLWDLPLDGLQLQMNLKHIGNKTKDIIRFLQQRL
KKAVPYYRMKLIVVGSPRSGKSSLIHHLMKLKRTQWRSDQHTIGVSVRDWSIRNKEKRNM
LLNVWEFSGGEECSGFHPHFMSSRALYLVLYDLSKGPSEIDAIKPWLFNIKAVAGQSPVI
VVGTHADVCEERLLQECVLKLQEELLSQTGFPVIKENHILCACEESESISRLRKAIYREL
VGFKIQGQPVMGQLIPDCYVELERRVLQERSHVPTDFPVLRHSRLLEIIQETQLQLEEGE
LPHAIHFLSEAGVLLHFDDPVLQLKDLYFIDPQWLCNIISQTLTLRSTGQWDGTRGVMQR
TTVEKFLNKSRCFPKDHLTQYFKLLEKFQIALPFGDDQLLIPSSLSDHRPVIELPHCENS
EVIVRLYEMPYFPMGYWPRQISRLLEVSAFLLYGKEKALRPNRIYWRKGIYLSWSAEAYC
LMEALSLEDNPASFIKITVPCSRKGCVLFGQVVDHIDSLLEEWFPGLLATDVHGTGETLL
KKWAVYSFSDGQNCQKMLLEDLLSNINADGLLVNPEDTSCTLPISQISPDLVLSDQLSST
ILDPEQLEMELSMEYMLGDGGFGSVYRAVYNNEEVAVKIFNKHASTLYVHRLVRQELTVL
GRLCHPSLVGLLAAGCNPHILVMELAPCGSLDSLFERENSSLSRKLQHRIALHVADGLRY
LHSSMIIYRDLKPHNILLFNLKTDAEVIAKITDYGIAQYCCSMGVRSSEGTPGFRAPEVA
RGNVIYNVQADVYSFGLLLYDLFTYGERITDGMKFPSEFDEVAVQGKLPDPVKDYGCSPW
PGFQSLMRDCLREYPQDRPTSAQVFDHLNSVEMLCLMRELTLMSFPGECFTVSGASGGAN
GGKNTRVWIGGGSSSQKLGCVTSLDLETGGSLSQEIDSSPILCIVIIRAPGSCSDWLVAG
TQSGSLYIMDTISAEVLHCLKCVKDSVTSLYFHTHRQLKNYLLVGTADGSLVIYEDSVLK
VKDGGPVKTLQVGDVNTPLMCLGPFSQNQERRELWAACGSKVFSLSVAYDISRSIDTKPK
QLYPQQGRLSSDPCISRLAVDKHMYVSKRGGHTVEVWDKKTERMVNLIDCAQLLGLSPTK
KPKAPSEDQSRQMVPSSATVKALLVQHSGTLWIGTKAGHILLVEVSSCQLLQTISPHCHS
IRCMGSALLDAPNRKNVILVLGRRQRMPQDQIKTQAEDSVLTVWNSSLPLEVRDLLRHCE
LRDKLTSKMRETLLN
NT seq
7608 nt
NT seq
+upstream
nt +downstream
nt
atggctgataaagaggagttaggaatcaggctgaagaagcttctggtgaggttgaacctt
caagaggggaagcagttgggcaccattgtccagatcatacaggacctcctgttcctgtcc
catacggatcactgcgttgagctctttgccgatcaaagcgtccacatgcctctgatgctg
gtgctgtcttcgcatttcaacagcaaagttcagcaggtaggctggtctctgctgtgtcgt
ctgatggagatctgtcccgccactctggatagtctggcctgcccagtggaatatgagttt
actgaggtgcacaagcagattcttaaggtgcttacaatgtatgctaaagactctaagatg
atgatggtgggcctgagagctctggctctgctgctgaagtcaggtgagattgtgatgcga
gttctgtatgagaaggaagatgatgtgtttttcttgattctggaggccatgaggtcattt
gatgacaaagaagaggttcagctacaaggatgtgctgctttacaactactgctgcaaaga
atttctgatgctcatctgttggagttcattgagaacaaggaccatgaggtgattttaaat
gcactcaggcggttcatggacagtgagaatgtggtgctgcaagctctgagagtcctcata
ccactggctgctccagccagcaatattgagattctgatgtctaaacccgttaaatgctac
agtctactatgtcaagctatggacatgtggcttgactcagaggccatacaggtggctggt
tgctgtttattacggaaatttacatcagagagttaccataacatactggtgctgaatggt
gtccataaggtggcggtgaaagcatgtgtctcttatcctgagaatgccacactgcagacc
gaggccttttcctgtctaagtgcactcttggagtgtattgtacagaatgaagggctgggc
aaagagtggaacgaggaagacggagggaaacagaaagttctggtaaagaaagaagccacc
caagcggaagagatgctcatatggagagaggcctgttacaccgctttggagagacatgct
gacgatgccgcagtgcaggaagctgcatgttgggccctaaacagcttgctgcttcattgc
aactcatccaaccatgtggaactggaaggaaggcctcctcttcattctctcgtcatggct
gccatgcttttgcattcatccagtgtgggggttttccaagctgcttcctgtacactacac
acactaatagagcgccacagtaggatgcgggctcagctgctgtcacatggcattcatgtc
aacattgtggttctgatgcagaaacatgaaagctctagcgccgtgtgtgaaagtgcctgc
aaactgcttcacatcctcttccaaggaccgagggcaagtctagatgacgcgaccctaatt
ctcggtcagatcctgactgctctgaagacacataatttcattcctgaagttcagctggag
ggtctcagagcaagtttagtccttctaaacccagacaggagtttaagagaacatggcgca
tcagtggcggatcctgatacagtggatgtgtccctgcgggtgctgaagaaccagtgtgta
ctagagggagctcacgctgtttacctacaggcacttaataggtttatcagtagtgaggag
attcaggagtgtggactgggtttactctcaacactggctgactcttctggagccgttgac
ctcatgtgccagcagggcgcgatagatacggttcttcatacgctgcagatgtttccacag
gggcgtgatgttcactactggggccttagtcttctgtttcacctcatctctaagaagaag
ctctcttgtatgatggtgcctgtactggcatcggttttggtcagctcaatacggcaacac
agagatgacacagtcatgcttctaaagggttttcaggcggtgttgaagttgttggacact
tgctcgagtgctgcagcatggctacagaaagaagcctttgagaaagacatcttccagatc
ctgcgggaaaagacagcagacgcgcgcctagatcgattgcagggaaggagttgcctgtgc
ctgtctaagatggtggcggacagcgagatcatgtacgcgctgctggagagagcgtgtgag
gaaggtgacgtagatatggcagaatgtctcatccagctgggcgctgacatcaacaagaaa
acaaaaagtgattcgctcatatatcagatttgtgatcgagggtctcctctagctctgctg
gagctgctggtatctgcaggtgttcatgagcaacagttacgtggagctctaagcgtgtgt
atcaggagaggcgatgaccctgcgatcaccctcctcctcgcccgtctggggctggaccat
gccaacaacgccctgtgcctcgggagcttccgcctcggacaaatgaaggcggcatggctc
aatgctctgctctctgagcgcaagactcaatctccagtcagcaagaagaacaataaaggt
cagcgtttggccagacagatcttgtcactccagaggaacaaaagctttgtgggagttagt
agattacggagtgatgccagcacatcagaatatttcaccgatgaggaaagtgacgactca
cacatgtctttagatgaaagcttggccctcgtgtttgatgacatggagagtgacgggagt
gacgggccttcacaaggatcattgctttttggcgattcaccagaagtgggcaggaaacct
gcttggagacacaggagtctgcgtagacgtgctaattcagagggaggccacggagacacg
gatccaagtgtccctcggcataagcgatttaactctcacaacactagagggcagggcttc
actgaaagctccactcctggtgctttccctctggccgtagacaaagaacccatccgtctg
ctcgatctctcaggaaatgagctgggcaatctgtcctgtttgatgggtgtgagctctctc
aaacagcagattgaaaaccttttacggcttgatttgagcagcaacagtttatcagagttt
cccagtgttctctgtcagaatttaagaagtcttacccgtctagatcttcaaggcaaccaa
ctgcagtcacttcctgtggaactcctgggtttgcccgctttaagcacgctcaatgtttct
cgtaactgcattggtcctcttttgctcctggacccaactgtgcgcagtccagccttacgc
cagctcaacctctccttcaaccagctcactgtctttcccttccagctggggcaggccatg
gacagattagaggagctctccttggagggcaatcagatatcagcactgtctctcccactc
tgcctgcctgaactgaaagttttagacatcagtaagaatcaagttaataacatttcagac
aattttcttactgagtgcctcaagctggaaactttcaacgcttcagttaaccaaatcagt
tcattgtcacaccttccctcaaaaataaccactgttaaattatcacagaacaatttcaca
tctatccctgaaataatcatcaacttgccaaatttgcgttcggtggatatgagaaataac
agtattagtgatctgccaggtccatctttctgggtcagtgtaaacctaagagagctgatg
ttcagtcataatcaaatctctgtgctcgacctgagcggcccgacgtacaagtgggccaga
ctggagaaacttactttaagctccaacaaactcactgagattcctcctcagatcggtatg
ttggaggacctgacgtctctagatgtgagtcagaatcaaggtttgcgctctttccctgat
gagatgggaaagctggttcacttatgggatctacctctagatggtctgcagctccagatg
aacctcaaacatattgggaacaaaaccaaagacatcatcagattcttgcagcagcgtctg
aagaaagctgtcccctattatcgcatgaaactcattgtggtcggcagcccgcgtagtggg
aaaagctctttgattcatcatttgatgaaactcaaacgcactcagtggcgatctgatcaa
cacactattggtgttagcgtcagagactggtccatcaggaacaaagaaaagaggaacatg
ttgctgaatgtatgggagttctctggtggcgaagagtgcagtggatttcacccacacttt
atgagctccagggcgctatatctagtgctgtatgacctgagtaaaggacccagtgagata
gacgccatcaaaccctggctctttaacattaaagctgtagctggacagtctcctgtgatt
gtggttggaactcatgcagatgtgtgtgaagagcgcctcctacaggagtgtgttctgaag
ctacaagaggagctgctgtctcaaacggggtttccggtgatcaaagagaaccacatactg
tgtgcctgtgaggagtcagagtccatcagcaggttgcgcaaagccatctatagagagctc
gttgggttcaagatccagggtcagccggtaatggggcaactgattccagactgttatgtg
gagttggagaggagagttttacaggagaggtcacatgtacccactgatttcccggtgctc
agacacagcagactactagagatcatacaggaaacacagctgcagctagaggagggagag
ttaccccatgctatccacttccttagtgaagctggtgtcctgctgcactttgatgatcca
gtgctacagctaaaggatttgtacttcattgacccacaatggctttgtaacatcatctca
cagacgctgactctgaggagcactggtcagtgggacggcactagaggagtgatgcagcga
accactgtagaaaagtttctgaacaaaagtcgctgtttcccgaaggatcatctgactcag
tacttcaaactattggaaaagtttcaaatagctctgcccttcggagatgaccagttactt
atacctagcagcctgtcagatcacaggccggtgattgagctcccccactgtgagaattca
gaggtgattgtccggctttatgagatgccgtacttccccatgggctactggcccagacag
atcagccgtctgttggaagtgtctgctttcctgctctatggcaaagaaaaagcattgaga
ccaaacaggatctactggaggaagggtatctatctaagttggtctgctgaagcttactgt
ttgatggaggccttgtcactagaagacaaccctgctagcttcatcaagatcacggtcccc
tgctctcgcaaaggttgtgtcttgtttgggcaggtggtggatcacattgactctttgctg
gaggaatggtttcctggcctcctcgccactgatgtccatggcactggagagacactgctt
aagaaatgggctgtgtacagctttagcgatgggcaaaactgccagaagatgctgctggaa
gatctactgtccaacatcaatgcagatggtttgctggtgaacccagaggacaccagctgt
actctgcccatctctcagatatctccagacctggtgctgagtgaccagctgtccagcact
atactggatccagagcagctggagatggagctctctatggagtatatgttgggagatgga
ggcttcggctctgtttatagagctgtgtacaataatgaggaagttgctgtgaagattttc
aataaacatgcatctacgctttatgttcatcggctggtgcgacaggaactgacggtactt
ggcagactgtgtcaccccagtctggtggggcttttggctgctggttgtaacccacacatt
cttgtgatggaactcgccccatgtggctctctggactcactgtttgagcgtgaaaatagc
agtctgagccgcaaactacagcacaggatagcactgcatgtggcggatggtctcagatat
ttgcactcatctatgattatctaccgagatctgaagccgcacaacattctcttgtttaac
ctgaagacggatgccgaagtcatcgctaaaatcacagactatggcatagcacagtactgc
tgcagtatgggtgtccgcagctcagaaggaacaccaggttttagagccccggaggtcgcc
cgtggtaatgtcatctataacgtccaggcagatgtatattcttttggtctgcttctgtat
gacctttttacctacggcgagcggataactgatggaatgaagtttcccagtgagtttgat
gaggtggctgtgcagggaaaactaccagatccagttaaagattacggctgttctccatgg
cctgggtttcagtctttgatgagggactgtttgagggaatacccacaggaccgacctaca
tctgctcaggtgtttgatcatctgaattctgtagagatgctttgtctgatgcgagagctg
acattgatgagttttccgggtgagtgtttcactgtctctggtgccagcggaggtgcaaac
ggaggtaaaaatactcgtgtgtggattggaggtggcagcagcagccagaaattgggttgt
gtgacatcgctggatctagaaacagggggaagcttgagccaggagattgacagcagtcct
atcctctgcattgtgatcatcagagctccagggtcatgcagtgactggttagttgctggt
acacagtcaggttcactctatatcatggatactataagcgcagaggttctgcactgtcta
aagtgcgtcaaggactctgtgacatcactatactttcacactcacagacaactaaagaac
tatcttttggtcgggacagcagatggatcactagtcatttatgaagattcagtcctgaag
gtgaaggatggtggtccagtgaaaacactgcaggttggtgatgtgaacactcctctgatg
tgtcttggtccattcagtcagaatcaggagcgaagagagctgtgggcggcctgtggcagc
aaggtgttctcactctcagtggcatatgacatcagtagaagcatagacaccaaacccaaa
cagctgtacccgcagcagggtcgactcagcagtgatccttgcatatcacggttagcggtg
gacaaacatatgtatgtaagtaaaaggggaggccatactgtggaggtctgggataagaag
accgagaggatggtgaacctcattgactgcgcacagttactcggattaagtcccaccaaa
aagcccaaagccccaagtgaggaccagtctagacaaatggtaccatcttcggcgactgtt
aaagctctgttggtccagcacagcggtactctgtggattgggaccaaagcaggacacatc
ctgttggtggaagtctccagctgccagctactgcagaccatcagccctcactgccactcc
atacgctgcatgggctcagcgctgctagacgcacccaacagaaagaatgttattttagta
ttgggtagacgacaacgcatgccacaagaccaaatcaaaacacaagctgaggattcagtg
ctgacagtgtggaatagttcacttcctctggaggtcagagatctgctcagacactgtgag
ctacgagacaagctcaccagcaaaatgagagaaacgcttctcaactga
DBGET
integrated database retrieval system
