Garra rufa (doctor fish): 141334763
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Entry
141334763 CDS
T11039
Symbol
araf
Name
(RefSeq) serine/threonine-protein kinase A-Raf
KO
K08845
A-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
grf Garra rufa (doctor fish)
Pathway
grf04010
MAPK signaling pathway
grf04012
ErbB signaling pathway
grf04068
FoxO signaling pathway
grf04270
Vascular smooth muscle contraction
grf04810
Regulation of actin cytoskeleton
grf04910
Insulin signaling pathway
grf04914
Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:
grf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
141334763 (araf)
04012 ErbB signaling pathway
141334763 (araf)
04068 FoxO signaling pathway
141334763 (araf)
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
141334763 (araf)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
141334763 (araf)
04914 Progesterone-mediated oocyte maturation
141334763 (araf)
09153 Circulatory system
04270 Vascular smooth muscle contraction
141334763 (araf)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
grf01001
]
141334763 (araf)
Enzymes [BR:
grf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
141334763 (araf)
Protein kinases [BR:
grf01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
141334763 (araf)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
Pkinase_fungal
Kdo
TUG-UBL1
Motif
Other DBs
NCBI-GeneID:
141334763
NCBI-ProteinID:
XP_073696090
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Position
5:complement(37482288..37497762)
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AA seq
606 aa
AA seq
DB search
MSNTSSCSSSGETSPDDTPRGGGTIRVYLPNKQRTVVNVRPGQTVYDSLDKALKVRGLSQ
DCCAVFRLLEGRKRLTEWDTDITPLVGEELLVEVLDDVPLTMHNFVRKTFFKLAYCDFCH
KFLFNGFRCQTCGYKFHQHCSSKVPTVCVDMDTVTKRCGPNTEDCPSILIYPATNSISQS
NITLSADSLGGEQLSPTSGFCVFMRGEDGQSLQRHRSTSTPNVHMVSSLEPGAAGLLEEP
FKISTMGQESSPKPSTSPPHLGSPGRRPPKSPSEPKERKQSSSDDKKKVHRGGYRDSSYY
WEVHSREVSMLKRIGAGSFGTVYKGKWHGDVAIKILKVTEPTPEQLQAFKNEMQVLRKTR
HVNILLFMGFMTKPNFAIITQWCEGSSLYRHLHVTETKFDTMRRIDVARQTAQGMDYLHA
KNIIHRDLKSNNIFLHEGWTVKIGDFGLATVKSRWSGSQQVEQPSGSILWMAPEVIRMQD
TNPYTFQSDVYGYGVVLYELMSGTLPYSNINNRDQIIFMVGRGYLSPDLSKLYSNCPKSM
KRLIIDCLKFKRDERPLFPQILVGIEQVQDLLPKIERSASEPSLHRAVHAEDLNPLLLHT
TRLMPL
NT seq
1821 nt
NT seq
+upstream
nt +downstream
nt
atgtccaacacatcctcctgttcctcctcgggggaaaccagcccagatgatacaccccga
ggtgggggcaccattcgtgtctacctccccaacaagcagcggacagtggtaaatgttcgg
cctgggcaaactgtctatgatagtctagataaagctctgaaagtcagaggcctaagccag
gattgctgtgctgtctttcgccttcttgaaggccggaagagacttacagaatgggacact
gacatcacacccctcgtaggggaagagcttctggtagaagtgctggatgatgttcctctt
accatgcacaacttcgtacgtaaaacattctttaaattagcttactgtgacttctgccac
aagttcttgttcaatggcttcaggtgtcagacatgtgggtataaatttcaccagcactgc
agcagtaaagtccctacagtatgtgtggatatggacaccgtcacaaaacggtgtggtcct
aatacagaagactgcccttcgatattgatatatccggccaccaattccatatcacagagt
aacattaccttatctgcagattctcttggaggagaacagctgtctcccacatcaggcttc
tgtgtgttcatgcgaggagaggatggtcagtctctccagaggcatcgctccacctcaacc
cccaacgtccacatggtcagctcgctggagcctggcgctgctggcctcttggaggagcca
ttcaaaatcagcacaatggggcaagagtcctctcccaagccttccactagcccaccccac
ctagggtcaccaggaagaagaccccccaaatccccttctgagcccaaggaacgaaagcaa
tcctcatctgatgataaaaagaaagtgcaccggggaggttacagagactccagttactac
tgggaggtgcactcacgggaggtgtccatgttaaagaggattggagcaggttcttttggg
actgtctataaaggcaagtggcatggagacgtggctatcaagattcttaaagtgacagag
cccacaccggagcagctccaggcctttaaaaatgagatgcaggttttacgaaaaacacgc
cacgtcaacattctgctgttcatgggcttcatgacgaagcctaattttgccattatcaca
cagtggtgtgaaggcagcagcctctaccgccacctgcatgttactgagaccaagtttgac
accatgcgccgtatcgatgttgctcgccagaccgcacagggcatggattatcttcacgcc
aagaatatcattcatcgggacttgaaatctaataatatcttcctgcacgaaggctggacg
gtaaagatcggtgactttgggctggccacagtaaagtctcgctggagtggctctcagcag
gtcgaacagcccagtggctccatcctgtggatggcccctgaggtgatcagaatgcaagac
actaacccatacaccttccagtcagatgtatatggatatggagtggtgctctacgaactg
atgtctgggactttgccttattccaatatcaacaaccgcgatcagattattttcatggtg
ggtcgtgggtacttgtctccagacctcagtaaattatacagtaactgccctaaatcaatg
aagaggctcatcatcgactgtctgaaattcaaacgtgatgaacggcctctcttcccacag
atcttggtgggcatcgagcaggtccaggatctgttgccaaaaatcgaacggagtgcctct
gagccctctctacaccgtgctgtacacgccgaggatctgaacccgcttctccttcacacc
acacgcctcatgcctctgtga
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