Garra rufa (doctor fish): 141345762
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Entry
141345762 CDS
T11039
Symbol
bckdha
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
grf Garra rufa (doctor fish)
Pathway
grf00280
Valine, leucine and isoleucine degradation
grf00640
Propanoate metabolism
grf00785
Lipoic acid metabolism
grf01100
Metabolic pathways
grf01210
2-Oxocarboxylic acid metabolism
Module
grf_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
grf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
141345762 (bckdha)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
141345762 (bckdha)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
141345762 (bckdha)
Enzymes [BR:
grf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
141345762 (bckdha)
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Motif
Pfam:
E1_dh
DXP_synthase_N
DUF6409
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
141345762
NCBI-ProteinID:
XP_073706763
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Position
11:23337600..23356553
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AA seq
446 aa
AA seq
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MAAARGVKKLYAIGLHAIRQNTALKATTFLQQRAFRVNGALRQQPFDSSAEKPQFPGASA
EFIDHLEFIQPNVISGIPVYRVMDRQGQIINPSEDPKLSKETVLNFYQKMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHIGSAAALEPTDIVFGQYREAGVLMYRGFPLDLFMAQCY
ANADDLGKGRQMPVHYGCKDLNFVTISSPLATQIPQAAGAAYAMKRENTNRVVVCYFGEG
AASEGDAHAGFNFSATLECPLIFFCRNNGYAISTPTNEQYRGDGIAARGPGYGLMSIRVD
GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRHYMTARNWWGEDEERAWRKQSRKLVMEAFEKAERRLKPNPDLLFTDVYDEMNPL
LAKQREAMWRHVQQYKEHYPLDLYEK
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atggcggccgctagaggagttaagaaattgtacgccattgggcttcacgcaattcgtcaa
aatactgcgttaaaagcaacaacgtttttgcagcaaagagcattccgcgtgaatggagct
cttcgccagcagccgtttgattcttcagcagagaagccgcagtttcccggggcgtcggcg
gagtttattgatcacctggaatttatccagcccaatgtgatctcaggaatccctgtgtat
agggtaatggacagacagggccagatcatcaatccttctgaagatcctaagctttcgaaa
gagactgttttaaatttctatcagaagatgacattactcaacacaatggatcgtattctt
tatgagtctcagaggcagggccgtatctctttctacatgaccaattatggtgaggagggc
acacacattggcagcgctgcggctcttgaacctactgatatagtcttcggccaataccga
gaagctggtgtattgatgtacagaggctttcctctggatctgttcatggcacagtgctat
gccaacgctgatgaccttggcaagggcagacaaatgccagttcactacggctgcaaagac
ctcaattttgtcaccatctcctcaccacttgccactcagatcccccaagcggccggggcg
gcgtatgcaatgaagagagagaacacaaaccgtgtggtggtctgttactttggagagggg
gccgccagtgagggagacgcacatgctggatttaatttttccgccacccttgagtgtcct
ctcatatttttctgccgcaacaacggttatgctatctcaacaccaaccaatgagcagtac
agaggagatggtattgctgctcgaggtccaggatatggactgatgtcgatacgcgtagat
ggaaatgatgtttttgcagtgtacaatgccacaaaagaagcccgacgcagagcagtggct
gaaaaccagcctttccttattgaagccatgacctacaggatcggtcaccacagcaccagt
gacgacagctctgcgtaccgctccgtcgacgaggtgaactactgggacaagcaggaccac
cccatctctcgcctgcgacactacatgaccgcccgaaactggtggggcgaggacgaggag
cgggcctggagaaagcagtcccgaaaactcgtcatggaggcctttgaaaaagcagagaga
cgtctaaaacccaatccagacctgctgttcactgatgtctacgatgagatgaatcctctt
ctagccaagcagagagaagccatgtggcggcacgtccagcagtataaagagcattaccca
cttgatctctatgagaaataa
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