Garra rufa (doctor fish): 141345946
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Entry
141345946 CDS
T11039
Symbol
plcg2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
grf Garra rufa (doctor fish)
Pathway
grf00562
Inositol phosphate metabolism
grf01100
Metabolic pathways
grf04012
ErbB signaling pathway
grf04020
Calcium signaling pathway
grf04070
Phosphatidylinositol signaling system
grf04370
VEGF signaling pathway
grf04625
C-type lectin receptor signaling pathway
Module
grf_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
grf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
141345946 (plcg2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
141345946 (plcg2)
04370 VEGF signaling pathway
141345946 (plcg2)
04020 Calcium signaling pathway
141345946 (plcg2)
04070 Phosphatidylinositol signaling system
141345946 (plcg2)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
141345946 (plcg2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
grf04131
]
141345946 (plcg2)
Enzymes [BR:
grf01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
141345946 (plcg2)
Membrane trafficking [BR:
grf04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
141345946 (plcg2)
Endocytosis
Macropinocytosis
Phospholipase C
141345946 (plcg2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
PH
SH3_9
EF-hand_PLCG1
SH3_2
PH_12
PH_14
Motif
Other DBs
NCBI-GeneID:
141345946
NCBI-ProteinID:
XP_073706966
LinkDB
All DBs
Position
11:complement(36061530..36182819)
Genome browser
AA seq
1240 aa
AA seq
DB search
MAGRVKQGDLTEYSKSLIKRDLEMGIVMTVYRQRMERLTVQVIMETRQVAWSRTANKTEG
VLDLFEIREVRAGKNSKDFDRFKDSKDKNTDPNSCFTIFYGSQFVLNTLSLGADSVEDAE
KWLTGLELLRQETLEAHTPEIIESWLRKQMYSVDQTKKNSITLKELKSLMPQMNFKVPSG
RFLKDRIAGLGAKKEVLDFEQFHKFYNLLMFENQKIILDEFKKESCAFILGNSDQPIQLA
DFQRFLLYHQRETWANNLNQVRELMTTFIDDTMRKTNDPAFTVEEFLSFLFSKENSIWDE
KFSEICPLDMNNPLSHYWINSSHNTYLTGDQLRSESSTEAYVRCLRLGCRCVELDCWCGP
DEPVIYHGRTMTSKIKFKDVVKAINDHAFATSEYPVVLSIEEHCDVKQQKFMAQVFKDIF
QDKLLTEPLEPEAEQLPSPTQLKGKIIIKHKKLNIDDAFIKKDLRKGDKQGELSIWDPID
ERWYKHYCVIENKTLYYAEENELEDDVGKATQGGTELHQSEPWFHGRMSEGRQTAERLLQ
EYCAESGAVDGTFVVRESDTFVNDCTLSFWRSGRVQHCRIRSCLEGGHTVYFLTENLHFP
SVYALIQYYRENLLRCQDFNLRLSDFVPRPDQHLLEGWFYSNLSRGEAEDYLMRIPRDGA
FLIRQREDSDSYAITFRGEGMVKHCRIHKDGSMYVLGTSSEFESLLELVEYFKKKPLYRK
IKLRYPVTPELVDRFSSITVSASLYDAKQYVEANEIEPSLPHSTVKALYDYRAMRTDELS
FCKGALIHNVTKEANGWWKGDYGGKIQHYFPSNYVEEVANSSEANYQGDEENPLGELCKG
IVDISKCTVVRSAKHGKPVVVTLQDKENKEMPFDLSTETTEELYEWYQVAWDITQREENR
EFEKKKQRDIESKEEVASEMSEIVVYCQPRSKDKDRFDNYTYKEVRSFVENKTPSRNKST
QFMMYNRKALSRVYPKGQRVDSSNYDPYPLWMCGCHMVALNFQTADKYMQLNSALFSLNG
GTGYVLQPEMMRSDSYDPYQEKRNVRFTITIRVIGARHLPKPGRSIASPFVEIELCGQTD
DNKFKTTVCHDNGLNPIWLGPNFQPSEVFTFTVYDPDLTFLRFVVFEEDMFSDPNFLAQA
TFPVKGVRSGYRSVPLKNGFSENLELASLLVYVDIQQVEKVQEELYSSSKQLQKKQAELG
NEFCLYDTHTNLQRSVPPEFMYSEKKPNKQQKINNSKFYS
NT seq
3723 nt
NT seq
+upstream
nt +downstream
nt
atggcgggccgcgttaagcagggagacctgaccgagtacagtaagagtctcattaagcga
gacttggagatggggatagtgatgaccgtgtacagacagaggatggagaggcttacggtg
caggtcatcatggagacgcgacaggtggcctggtcacgcaccgccaacaagacagaagga
gtgttggacctctttgagatccgggaagtacgagcaggaaaaaactccaaagactttgat
cgattcaaggacagcaaagataaaaatacagacccaaactcatgctttactatattctat
ggctctcagtttgttctcaacactctcagtctgggagctgattcagtggaggatgcagaa
aaatggctaacaggactggagttactcagacaggagacattggaggctcacacaccagag
attatagaaagctggctaaggaagcagatgtactctgttgatcaaacaaagaaaaacagc
atcaccctgaaagagctcaagtctctgatgccgcagatgaactttaaagtaccaagtgga
cgttttttgaaggacagaattgcggggttgggagcaaagaaagaagttctggattttgag
cagtttcacaaattctacaatcttttgatgtttgaaaaccaaaagataattctagatgag
tttaaaaaggagtcgtgtgctttcatcttgggtaacagcgatcagcctattcaacttgcc
gattttcaaagattccttttatatcatcaaagagagacttgggccaacaatctgaatcaa
gtcagagagcttatgactaccttcattgatgacaccatgaggaagaccaacgatccagct
tttactgttgaagagttcctcagttttctcttctccaaagagaactcgatttgggatgag
aaattctcagagatttgcccactggacatgaacaatcctctgtctcactactggatcaac
tcttctcacaacacatatttgactggagatcaactgcgcagcgagtcctcaacagaagct
tatgtgcgctgcctgaggctgggctgtcgctgtgttgagttggactgctggtgtggtcca
gatgaacctgtcatatatcatggacggaccatgacctccaaaataaagtttaaggacgtg
gtgaaggccatcaatgatcatgcttttgcaacatctgagtatcctgtggtgctgtccatc
gaagaacactgtgacgtcaagcaacagaaatttatggctcaggtgttcaaagatattttc
caagacaagctcctgaccgagccgctggaaccagaagcggaacaactgccgtcaccaacc
caactgaagggcaagatcatcatcaagcacaagaaactgaatattgatgacgcctttatt
aaaaaggacctacggaaaggagataagcaaggagagctctccatctgggatccaatcgat
gagagatggtacaagcactactgcgtgatcgagaataagacattgtattatgctgaagag
aatgaactagaggatgatgttggaaaggcaacccagggtggtacagaacttcatcagtca
gaaccctggtttcacgggcggatgtcagagggcagacagaccgcagagagactgctgcag
gaatattgtgcagagtcgggggcagtcgacgggacatttgtagtgcgggagagcgacacc
ttcgtcaatgattgcaccctctcattctggcgcagcgggcgagttcaacattgtcgaatc
cgatcttgcttagaaggaggccacactgtctatttcctcacagaaaacctacacttcccc
agtgtgtacgcgcttattcagtattacagagaaaaccttctccgctgtcaggatttcaac
ttgcgcctctctgactttgtgcctcgaccagatcaacacctgttagaagggtggttttac
agtaacttgagtcggggtgaggcggaggactatctcatgaggatccctcgagatggagcc
ttcctcatcagacagagagaagattcagactcttacgccatcaccttcagaggtgaaggg
atggtgaagcactgtcggatacacaaagatggatctatgtacgtgctgggaacctccagc
gaatttgagagcctgctcgaattggtggaatatttcaaaaagaaaccactatatcgaaag
attaaactgcgctacccggtcacaccagaactggtggaccgcttcagttcgataaccgta
tctgcttcactttatgatgctaaacagtacgtggaggccaacgagatagagccgtctctg
ccccatagcacagtgaaggccctctatgactacagggccatgcggacggacgaactcagc
ttttgtaaaggtgctttgatccataatgtgaccaaggaggcaaacggatggtggaaagga
gattatggtgggaaaatacagcactatttcccttcaaattatgtagaagaagttgccaat
tcatctgaggccaattaccagggcgatgaggaaaatccattaggtgaattatgtaaagga
atagtggacatctccaagtgtactgttgttcgatcagctaaacacggcaagcctgtggtg
gtgacactgcaggataaggagaataaagagatgccgtttgatttgtccactgagaccacc
gaggagctgtacgagtggtatcaggtggcctgggacatcacacagagagaggaaaaccga
gagtttgagaaaaaaaagcaaagggatattgagtcgaaagaagaggtggccagtgagatg
tctgaaatagttgtttactgccagcctcgcagcaaagacaaggaccgctttgataattat
acctacaaagaagtccgctccttcgtagaaaataagacaccctccagaaacaagtcgact
caatttatgatgtataaccgcaaagcgctgagccgcgtctaccctaaaggccagcgagtg
gattcctccaactatgatccgtatcctctatggatgtgcggatgccacatggtggcactc
aacttccaaaccgctgataagtacatgcagctgaacagcgccctcttcagtctgaatgga
ggcacaggatatgtgcttcaacctgagatgatgcgcagtgattcgtatgacccttatcag
gagaagaggaatgtcagatttactatcaccattagggtgataggagcgcgacatcttccc
aaaccaggacgaagcatcgccagtccctttgtggagatcgaactgtgtggccaaacagat
gacaacaaattcaagactactgtttgccatgataacggactgaaccctatatggcttggg
ccgaactttcagccttcggaggtatttactttcaccgtgtatgacccagacctcactttt
ctgcgctttgtggtctttgaggaggacatgttctctgaccccaatttccttgctcaggct
acgttccctgtgaaaggcgttcgctcaggatacagatcagtccctttaaaaaatggcttc
agtgaaaacctggagctggcgtctctgctggtgtatgttgatatacagcaggtggagaaa
gtgcaggaggaactttactcctcctcgaaacagttgcaaaagaaacaggcggagttaggc
aacgagttttgcctctatgacactcacaccaacctgcagcgcagtgtgcctcctgagttc
atgtactcagaaaaaaagccaaacaaacagcaaaaaatcaacaacagcaagttctactca
tga
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