Garra rufa (doctor fish): 141347548
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Entry
141347548 CDS
T11039
Symbol
jak1
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine-protein kinase JAK1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
grf Garra rufa (doctor fish)
Pathway
grf04217
Necroptosis
grf04620
Toll-like receptor signaling pathway
grf04621
NOD-like receptor signaling pathway
grf05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
grf00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
141347548 (jak1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
141347548 (jak1)
04621 NOD-like receptor signaling pathway
141347548 (jak1)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
141347548 (jak1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
grf01001
]
141347548 (jak1)
Enzymes [BR:
grf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
141347548 (jak1)
Protein kinases [BR:
grf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
141347548 (jak1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
ABC1
Kdo
Motif
Other DBs
NCBI-GeneID:
141347548
NCBI-ProteinID:
XP_073708649
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All DBs
Position
12:27155282..27189178
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AA seq
1027 aa
AA seq
DB search
MPELAVMELGRQLCGKMKKQRKAEMTVPTLMKGLEIHFYLPDTHQLEYFKDCHTVEDLCV
EAAKRCHISPLCHNLFALYEESQDLWYAPNHVFKITEETSIKLHYRMRFYFTNWHGTSET
ESPVWRHSLCKQKGVLVSQREKGPEGTPLLDAASLDYLFAQGQYDFLRGLAPVRAPQSEL
ELHEIENECLGMAVLAITHHAKSNDLPLSGAGAETSYKRFIPDSLNRTIKQRNFLTRIRI
NNVFRNFLNEFNSKTIQDSNITLYDLKVKYLSTLETLTQGLGRETVEPKIMKVSAESEGS
PAHTLPLGDEGMGYEVQVSGATGISWRRKPVLNLLIVKEKNKSKKNKADNKQKNDKKKDS
GWTVFSDFYEITHLVIKESCVTIYRQDNKTMAAVHLAANSCEVSNFSQPIQDQIPYPANQ
ISNLLVMTTNREPXPQRQPQVSQLSFHRILKEEIVQGEHLGRGTRTNIYAGILKLKSEDD
DDMGGYSQEVKVVLKVLGSGHRDISLAFFETASTMRQISHKHIALLYGVCVRHQENIMVE
EFVQYGPLDLFMRRQSTPLSTAWKFQVAKQLACALGYLEDKKLVHGYVCSKNILVARDGL
DGEGGPFIKLSDPGIPITVLSREECVDRIPWIAPECVQDTANLSIAADKWGFGTTLWEIC
YNGEIPLKDKKLTEKERFYAAQCQLATPDCDELAKLMTHCMTYDPRQRLFFRAIVRDIDV
VEKQNPSIQPVPMLEVDPTVFEKRFLKKIRDLGEGHFGKVELCRYDPRGDRTGELVAVKS
LKPENREEQNSNLWREIHILRELYHENIVKYKGICHEEGGRSIKLIMEFLPAGSLKEYLP
RNKSQIDIKTLLSYAVQICQGMDYLGSRNYIHRDLAARNVLVENENTVKIGDFGLTKSIK
DNEGYYTVKDDLDSPVFWYAPECLIHCKFYRASDVWSFGVTMYELLTYCDTSCSPMSVFL
KMIGPTHGQMTVTRLVKVLEEGKRLPKPDGCSDRLYSLMRRCWEATPEKRIDFKSLIADF
QQMIENQ
NT seq
3084 nt
NT seq
+upstream
nt +downstream
nt
atgccagaactagcagtcatggagttgggcaggcaactgtgtgggaagatgaaaaaacag
aggaaggcagagatgaccgttccgactctcatgaaaggactggaaatccacttctacctg
cctgacacacaccagctcgagtacttcaaagactgccacactgtggaagacctgtgtgtg
gaggctgccaagagatgccacatctcacctttgtgccacaacctgttcgcgttgtatgaa
gagagccaggatctttggtatgctcccaatcatgtgttcaagatcacagaggagaccagc
atcaaacttcattaccgtatgaggttttatttcacaaactggcatggcactagtgagaca
gaatctccagtttggagacactcgctttgcaagcagaaaggggttttagtctctcagaga
gagaaaggccctgaggggacacctctactggatgctgcatctcttgactacctgtttgca
cagggccagtatgactttctgaggggacttgctccagtgcgcgctccccagagtgagtta
gagcttcatgagatagagaacgagtgtttgggaatggctgttttggccattacccatcat
gccaaaagcaatgatctacccttatctggagctggagctgagaccagctataagcggttc
attccggacagtctgaatcggaccattaagcagcgtaacttcctcacacgcatacgcatc
aacaacgttttcagaaatttcctcaacgagttcaatagcaagaccatccaggacagcaac
ataactctttatgacctgaaggtcaagtatctctccactctcgaaacgttgacccagggc
ctgggtcgggagactgttgagcccaagataatgaaagtatcagctgagagcgagggatct
ccagcccacacacttcctttgggggatgagggaatgggctatgaagtgcaagtgtctgga
gccactgggatttcctggaggagaaagcctgtactgaatcttctgatagtaaaggaaaaa
aacaaatctaaaaagaacaaggctgacaacaagcagaagaatgacaaaaagaaagacagt
ggatggaccgttttctcagacttttacgaaatcacccacctcgtcattaaggagtcttgc
gtcaccatttaccgacaagacaataaaaccatggcagctgtgcatctggcagctaatagt
tgtgaagtctcgaatttcagccagccaatccaggatcagattccttatccagctaaccaa
atttccaacctattagtgatgaccacaaaccgagagcccngcccacagagacaacctcaa
gtcagccagttgagtttccaccgcatccttaaggaggagattgtacagggtgagcatttg
ggtcggggcacgaggaccaacatctatgctggtattctaaagctgaagagtgaggatgat
gatgacatgggaggatattcacaggaggtgaaagtggtcttgaaagtgctgggctcagga
cacagagatatctctctggctttctttgagacggctagcacgatgcgacagatctctcat
aaacacatcgccctgctctacggagtgtgtgttcgccatcaggaaaatatcatggtggag
gaatttgttcagtacggtcctctggatctgttcatgcgcagacagagcacacctctcagc
accgcatggaagttccaggttgccaaacagttggcttgcgcccttggctatctggaggat
aagaagctggttcatggatatgtctgcagtaagaacattctggtggctcgagatggtctg
gatggagagggaggaccctttatcaagctgagtgaccctggcatacccattactgtcctt
agcagagaagagtgtgtggacaggattccttggattgctcccgagtgcgtacaggacacg
gctaatctgagcatagcagcggataaatggggctttgggacaactctgtgggagatctgt
tacaacggagagattcctctcaaagacaaaaagcttacagagaaggagaggttttatgca
gcgcagtgtcaactggctacacctgactgcgatgagctggccaaactcatgacccactgt
atgacctacgaccctcgacagagactcttcttcagagccatcgtcagagacattgacgtg
gtggagaaacagaacccatctatacaacctgttcccatgctagaggtggaccctaccgtg
tttgagaagaggttcctcaaaaagatcagagaccttggagagggtcattttggaaaggtg
gagttgtgcaggtatgacccacggggggatcggaccggagagctggtagctgtgaagtct
ctaaagccggagaaccgggaagagcagaacagtaacctgtggcgtgagattcacatcctg
agagaactttaccacgagaacattgtcaaatataagggcatctgccatgaagagggtggg
agatctattaagctcatcatggagtttttgccagcaggcagtctgaaggaatacctcccc
agaaacaaatctcaaatagacattaaaaccctgctcagctatgctgtacagatctgccag
ggaatggactacctgggctctcgcaactatatccacagagacctggcagcccgaaatgtt
ctggtagagaatgaaaacacggtaaagattggagacttcggcctgaccaaaagcattaag
gataatgagggttattacactgtgaaagacgatctggacagtccggtgttctggtatgct
ccagagtgcctgatccactgcaagttctacagggcatctgacgtttggtcctttggagtg
accatgtatgagctgctcacttactgtgatacctcatgcagccctatgtcggtgttcctt
aagatgattggcccaacacatggccagatgactgttacccgattggtcaaagtgctggag
gagggaaagagacttccaaaaccagacggctgctcagacaggttgtacagtctgatgagg
agatgctgggaggcgacacctgaaaaacggatcgacttcaaaagcctgattgccgacttt
cagcagatgattgaaaatcagtaa
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