Gordonia rubripertincta: GCWB2_01485
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Entry
GCWB2_01485 CDS
T05629
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
gru
Gordonia rubripertincta
Pathway
gru00300
Lysine biosynthesis
gru00550
Peptidoglycan biosynthesis
gru01100
Metabolic pathways
gru01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
gru00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GCWB2_01485 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GCWB2_01485 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GCWB2_01485 (murF)
Enzymes [BR:
gru01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GCWB2_01485 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ASR01129
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Position
336099..337412
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AA seq
437 aa
AA seq
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MHFLASEVAASVGGELIGPDVQIDGASIDSRNVRPGQLFVPIVAERDGHDFIPSAREGGA
AAYFTSRDEVSRGTAIRVPDTALALADLGRAVRRRIPDRVVGITGSVGKTSTKDLLAGVL
QTTFRTAASEKSFNNELGLPLTLAGAPDDVEAVVLEMGARGIGHIDLLCSIASPTVGVIT
RVEGVHLELFGNIESVARAKGELVESLPADGIAVLNADHRYVAAMADRTSARVLRYGLSP
DADVYASDIVVDDELRASFRLHTPWGSTDMRLGARGEHQVPNALAAAAAGGGLGVSVEDI
ANGMSAAELSGLRMELAKTANGTIVLNDAYNANPTSMSAALKSLAALPVGRRVAVLGTMA
ELGSDSPAQHHAIALEAHELGIEVIAVDEPDYGDTARHTSGVDEAVAALGELGEGDAVLV
KGSRVAALERVAQALLG
NT seq
1314 nt
NT seq
+upstream
nt +downstream
nt
gtgcatttcttggcgagtgaggtcgcagcgtcagtcggcggcgagttgatcggtcccgac
gtccagatcgacggggcgagtatcgactcgcgcaacgtccggcccgggcagctcttcgtg
ccgatcgtcgccgagcgggacgggcacgacttcatcccgtctgcccgcgagggcggcgcg
gcagcctacttcacctcgcgcgacgaggtctctcgagggaccgccatccgggtcccggat
acggcccttgcccttgccgacctcggtcgcgcggtccgccgccggatccccgaccgcgtc
gtgggtatcaccggctcggtcggcaagacctccaccaaggatctcctcgccggtgtcctg
cagaccaccttccgcaccgcggcgagcgagaagtccttcaacaacgaactgggcctcccg
ctgaccctggccggagcgcccgacgacgtcgaggccgtggtcctcgagatgggtgcgcgc
gggatcggccacatcgacctgctgtgctccatcgccagcccgaccgtcggcgtgatcacc
cgcgtcgaaggggtccacctcgagttgttcgggaacatcgaatcggtggcccgcgcgaag
ggcgagctggtcgagtcccttccggccgacgggatcgccgtcctcaacgccgatcaccgt
tacgttgcggcgatggcggatcgcacctcggcccgggtgctgcggtacggcctgtcgccg
gacgccgacgtgtacgcatcggacatcgtcgtcgacgacgagctgcgagcgtccttccgg
ctgcacactccgtggggttcgaccgacatgcgtctcggcgcgcggggtgagcaccaggtt
cccaacgcgctcgcggccgctgcggcgggcggcggcctcggagtgtccgtcgaggacatc
gccaacggcatgtcggcggctgaattgtctggtctgcgaatggaactcgccaagaccgcc
aacggcacgatcgtgctcaacgatgcctacaacgccaacccgacgtcgatgtcggcggcg
ctgaagtcgctcgccgcgctgccggttggacgacgcgtcgccgttctcggcaccatggca
gaactgggatcggactccccggcccagcatcacgcgatcgcactcgaggcgcacgagctc
ggcatcgaggtcatcgcggtcgacgaacccgactacggcgacaccgcgcgccacacctcc
ggtgtcgacgaggcggttgccgcgctcggcgagctcggcgaaggagatgcagtgctggtc
aagggaagtcgcgtcgccgcactggagcgggtggcgcaggccctgctcggttga
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