Geotrypetes seraphini (Gaboon caecilian): 117347412
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Entry
117347412 CDS
T09159
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
gsh
Geotrypetes seraphini (Gaboon caecilian)
Brite
KEGG Orthology (KO) [BR:
gsh00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
gsh03032
]
117347412 (TOP2A)
03036 Chromosome and associated proteins [BR:
gsh03036
]
117347412 (TOP2A)
Enzymes [BR:
gsh01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
117347412 (TOP2A)
DNA replication proteins [BR:
gsh03032
]
Eukaryotic type
DNA Topoisomerases
117347412 (TOP2A)
Chromosome and associated proteins [BR:
gsh03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
117347412 (TOP2A)
Centrosome formation proteins
Centriole proteins
117347412 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
OVT1
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
117347412
NCBI-ProteinID:
XP_033774213
UniProt:
A0A6P8PHM3
LinkDB
All DBs
Position
13:complement(66321136..66597673)
Genome browser
AA seq
1722 aa
AA seq
DB search
MEVEPLHPLFENQKVDKVKKSNDFKSKISVEKIYQKKTQLEHILLRPDTYIGSVEPLTQQ
MWVYDEDEGLSCRDVTFVPGLYKIFDEILVNAADNKQRDKSMSCIKVTIDVENNSISVWN
NGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDQKKVTGGRNGYGAKLCNIFSSKFTVE
TACKEYKKIFKQTWTNNMSKEDEYKLKPFDGDDYTCITFQPDLAKFKMQTLDKDIIALMS
RRAYDVAGSSQGVKVFLNGKKLPVNGFRSYVDLYTKDKVDETGNPLKIIHEVVNHRWEVC
LTMSEKGFQQISFVNSIATTKGGRHVDYVADQIVNKLIEVVKKKNKGGIAVKPFQVKNHM
WLFVNSLIENPTFDSQTKENMTLQAKSFGSTCLLSEKFIKAATGCGIVESILNWVKFKAQ
NQLNKKCSAVKHTKIKGIPKLDDANDAGSRSSQDCTLILTEGDSAKTLAVSGLGVIGRDR
FGVFPLRGKMLNVREASHKQIMENAEINSIIKIMGLQYKKTYDDNESLRSLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHSFLEEFITPLIKASKNKQEISFYSIPEFEDWKN
NAGNLKTWKIKYYKGLGTSTSKEAKEYFADMKKHRIPFTYSGPADDAAISLAFSRKQIDD
RKEWLTNFMDDRRQRRMHGLPEEYLYGKATKNLTFNDFINKELILFSNSDNERSIPSLVD
GMKPGQRKVLFTCFRRADKREVKVAQLAGSVAEMSAYHHGEQSLMMTIINLAQNFVGSNN
INLLQPIGQFGTRLHGGKDAASPRYIFTMLSPLTRLLCPPMDDNVLKFLYDDNQRVEPEW
YIPIIPLVLVNGAEGIGTGWACKIPNYDTREIVNNVRRMLEGEEPLPMLPSYKNFKGMIL
DLGPNQYLISGEVSVLNSTTIEISELPIRTWTQTYKEQVLEPMLNGSEKTPPLITDYNEY
HTDTTVRFLVTMTEQKLAEAEAVGLHKVFKLQSSLTCNSMVLFDHMGCLKKYESVLDIMK
EFFDLRLRYYGLRKEWLVGMLSAESSKLNNQARFILEKIQGIIIIENKPKKELIQVLIQR
GYDSDPVKAWKETQEKENEGDMTTEEEEEKSTAISSGPDFNYLLGMPLWYLTKEKKDELC
KQRDTKEEQLLDIKQKNPTDLWKEDLALFVEQLEQIEAREREDELVGMAGKPIKGKVGKP
KLKKLQLEETMPSPHGRRVIPRITTAMKAEATKKVKKRLKGEDPIAIKMEFGEEFEGSSL
EQSNREPLSLAERLSKKTKTDAGAKGTKGKKQAKLPFKPVKKEKRNPWSGSDSESMDSEE
PNTIEVTSRESVPRRAAAKNTYVLSSDEEQEPCHKELSEDEYIPPSADTIEPAVPKPKVA
PKKKKKETATEHRVEAEEAAPAVTASSSTKNTYVLSLDEEQDPCHKELSEDEYIPPLADT
IEPAVTKPKVAPKKKKKETAKEHRVEAEEAAPAVTASSSTKNTYVLSLDEEQDPCHKELS
EDEYIPPLADTIEPAVTKPKVAPKKKKKETAKEHRVEAAPAVTASSSIEIQDSDSENRMP
VAQPSASVVPSKKLAPKKHVLGKKTTANATSKQDKQQPSIMEALSKPKAAVKPSKSTASK
ATVPKASSMETDAEALGPKKAAPAKVKKVRKRKTSDSENSDSDFGLKKTTAIKKTKRADE
SFHINLDSESDSDSGLAVASRAKPQRIRKPIQYLEESDDNLF
NT seq
5169 nt
NT seq
+upstream
nt +downstream
nt
atggaagtggaaccgctgcatcctttgtttgagaatcagaaagtggacaaggtgaagaaa
agcaatgacttcaaaagcaagatatctgttgaaaaaatttatcaaaagaagacacaactg
gagcatatcctgctccggccagatacttatattggctctgtggaacccttgacacagcaa
atgtgggtttatgatgaagatgaaggactcagctgtagagatgtgacatttgttcctggc
ttatataaaatctttgatgaaattcttgtaaatgctgcagacaacaagcaaagggataaa
agcatgtcctgtatcaaagtgacaatcgatgtagagaacaactcaatcagtgtgtggaat
aatggaaaggggatccctgttgtggaacacaaggtagagaaagtctatgttccagctctc
atctttggacagctcttgacttccagtaattatgatgatgaccagaagaaggtcactggt
gggagaaatggttatggtgctaaactctgcaacatcttcagcagcaagttcactgtggag
acggcgtgcaaggagtacaagaagatctttaagcagacttggacaaacaacatgtcaaaa
gaagatgaatataagctgaaaccctttgatggggatgattacacctgcatcaccttccag
cctgacctggctaagttcaagatgcaaaccctggataaggatatcattgccttaatgtca
cggagggcttatgatgtagcaggctccagccaaggagtgaaggtctttctcaatgggaag
aagctgccggtgaatggattccgtagttatgtggatctttacacaaaggataaagtggat
gagacgggcaatccattgaaaatcatccatgaggtggtgaaccatcgctgggaggtgtgc
ctgacaatgagtgagaagggcttccagcaaattagctttgttaatagcattgctaccacc
aagggtggaagacatgttgattacgtcgctgatcagattgtgaataaactcattgaggtt
gtgaagaaaaagaataaaggaggtatcgcagtgaaaccttttcaggtgaagaaccatatg
tggctgtttgtgaattcactgattgagaacccaacctttgactcccagaccaaggagaac
atgactctgcaggcaaaaagttttggctcgacctgcctcctctctgagaagttcatcaag
gcagcaacaggctgtggcattgtagaaagcatcctaaactgggtgaagttcaaagcacag
aatcagctaaacaagaagtgctcagcagtgaagcacaccaagattaaaggcattcccaaa
ctggatgatgccaacgatgctggcagcagaagttctcaggactgtacacttatcctgact
gagggagactcggccaaaacactggctgtgtctggtcttggtgtgatcggaagggatcgt
ttcggggtcttccctcttcgaggcaaaatgctcaatgtgcgagaagcttcccacaagcag
atcatggaaaatgcagaaataaacagtatcattaagataatggggctccagtacaagaag
acatatgatgacaatgagtcacttcgcagtctgcgttatggaaagatcatgatcatgaca
gatcaggatcaagatggctcacacatcaaaggcttgctgattaatttcatccatcacaat
tggccctctctcctgagacacagcttcctggaggaattcatcactcctcttattaaggct
tctaagaataaacaggaaatctccttctacagtatcccagagttcgaagactggaaaaac
aatgcagggaacctcaaaacctggaaaataaagtattacaaaggtttgggcaccagcacg
tcaaaagaggcgaaagagtactttgcagatatgaagaaacatcggatacctttcacttac
tccggccctgctgacgatgctgcgatcagcctggcctttagtagaaagcaaattgatgac
cggaaggaatggctgactaatttcatggatgaccgaaggcaaaggaggatgcatggccta
ccagaggaatatctgtatggaaaagccacaaagaatctgacattcaacgattttatcaat
aaggagctgattctgttctcaaattctgacaatgagcgttcaatcccatccctggtcgac
ggcatgaaaccaggtcagaggaaagtcctgttcacgtgcttcagaagagctgacaagcga
gaggtgaaggtagctcagctggctggttctgtcgctgagatgtcagcttatcaccatggt
gagcaatctctcatgatgactataattaatttggcccagaactttgtgggtagcaataat
atcaacctcctacagcctattggtcagtttggcacaaggttgcacggagggaaagatgca
gcaagccctcgatacatcttcactatgctgagccctcttacacgtttactgtgtccaccc
atggatgacaatgtgctgaaattcctctatgatgacaaccagcgggtggagccggaatgg
tatataccaatcatccccctggtattagtgaatggtgctgagggcattggcacaggctgg
gcctgcaagattcccaactatgacacacgagagatagtgaacaacgttcgtcgtatgctg
gagggggaggagcctctgcccatgcttcccagttataagaacttcaagggaatgattctg
gacttgggtccaaatcagtacctaataagtggagaggtgtctgtgctgaactcaaccacc
attgagatctctgagcttcccatccggacttggactcagacttacaaagagcaggtgctg
gaaccaatgctaaatgggagtgagaagacacctccccttatcacagactacaacgaatac
cacacagatactaccgtccgtttcttggtgaccatgacagagcagaaactggcagaggct
gaagctgtgggactacacaaagtcttcaaactccagtcctccctgacctgtaattctatg
gtgctgtttgaccatatgggttgcctgaagaagtatgaaagcgtgctggatatcatgaag
gaattctttgacctccgactccgctactatggtttgaggaaggagtggttggttgggatg
ctgtccgcagaatcctccaagctgaacaatcaagcccgttttatcctggaaaagatacag
ggaataataattattgaaaacaaacctaagaaggaactgattcaggttctaatccagaga
gggtatgactctgatcctgtcaaagcctggaaagagacccaggagaaggaaaatgaagga
gacatgacgacagaggaagaggaggagaaatccacagccatctcatccggtccagatttc
aactacctgctggggatgcctctctggtacttgaccaaagaaaaaaaggatgaactgtgt
aagcagcgggacaccaaggaagaacaactgctggatatcaagcagaagaatccaacagac
ctctggaaggaagatctggctctgtttgttgaacagctggagcaaatagaagcacgagag
cgagaggatgagctggtgggtatggctgggaagcccatcaagggcaaagtagggaagccc
aaactgaagaagttgcagctggaggagaccatgccttcaccgcatggaaggcgtgtgata
ccgcgaatcaccactgccatgaaggccgaggcaaccaaaaaggtcaagaagagactcaag
ggtgaagaccccattgcaatcaaaatggagtttggagaggaatttgagggaagctcccta
gagcagagcaatcgggaacccttgagtctagctgaacggttatctaagaaaacaaagact
gatgcaggtgcaaagggtaccaagggaaaaaagcaggccaagctgccattcaaacctgtg
aaaaaagagaaacgcaacccctggtctggttcagacagcgagtccatggacagtgaggaa
ccaaacacaattgaggtgacatcacgggagtctgttccccgccgagcagcagcaaaaaac
acatatgtactcagttcggatgaagaacaggagccttgccataaggagctgagcgaggat
gagtacatccccccatcagcagacaccatagagcctgctgtccctaaacccaaagtggct
cccaagaaaaagaaaaaagaaaccgccacagagcacagggtagaagctgaagaagctgca
ccagctgtgactgcttcatcctccacaaaaaacacatatgtactcagtttggatgaagaa
caggatccttgccataaggagctgagcgaggatgagtacatccccccattagcagacacc
atagagcctgctgtcactaaacccaaagtggctcccaagaaaaagaaaaaagaaaccgcc
aaagagcacagggtagaagctgaagaagctgcaccagctgtgactgcttcatcctccaca
aaaaacacatatgtactcagtttggatgaagaacaggatccttgccataaggagctgagc
gaggatgagtacatccccccattagcagacaccatagagcctgctgtcactaaacccaaa
gtggctcccaagaaaaagaaaaaagaaaccgccaaagagcacagggtagaagctgcacca
gctgtgactgcttcatcctccattgaaatccaagacagcgacagtgagaacaggatgcct
gttgcacagccttcagcctctgttgtgcccagtaagaaactggcccctaaaaagcatgtg
cttggcaagaaaaccacagcaaatgccaccagcaaacaggataagcaacaaccttccatc
atggaggctctttcgaagcccaaggcagcagtgaagccaagcaagtccactgccagcaag
gctacagtgccaaaagccagttccatggagactgacgctgaggcactgggcccaaagaaa
gctgctcctgccaaggtgaagaaagtgcgcaagaggaagacctcagattcagaaaattct
gactcagattttgggttgaagaagacaacagccattaagaaaaccaaacgggcagacgag
agctttcatatcaacctggactctgaatctgactccgactcaggcttggccgttgcctcc
cgagcaaagccacagcgcatcaggaagccaattcagtacctggaagaatcagatgataac
ttgttttaa
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