Geotrypetes seraphini (Gaboon caecilian): 117359166
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Entry
117359166 CDS
T09159
Symbol
HSD17B2
Name
(RefSeq) estradiol 17-beta-dehydrogenase 2 isoform X1
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
gsh
Geotrypetes seraphini (Gaboon caecilian)
Pathway
gsh00140
Steroid hormone biosynthesis
gsh01100
Metabolic pathways
Module
gsh_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
gsh00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
117359166 (HSD17B2)
Enzymes [BR:
gsh01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
117359166 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
117359166 (HSD17B2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
Epimerase
NmrA
Peptidase_S49
NAD_binding_10
3Beta_HSD
Motif
Other DBs
NCBI-GeneID:
117359166
NCBI-ProteinID:
XP_033797343
UniProt:
A0A6P8R9K6
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Position
4:complement(21845628..21893084)
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AA seq
391 aa
AA seq
DB search
MDQLFAEASFLHYLGVSLLLGGAVLYKLRKNQVRLGKRCAFGVLLLALLEVFCFLALPGF
LGLSLFALSCLIFYVSISPGMLPVDSKAVLITGCDSGIGYALARYLDTVGFNVIAAVLNK
DGQGAVALKSSCSQRLSLLQLDVTNSAQIKKAYEEVKAVLHNKGLWGFINNAGVLGYVVD
GELLPIDMYKKCMEVNFFGAVEVTKTFFPLLRKARGRLINICSLGGYIPMPGLSAYGASK
AALSMFSGVMRQELSKWGVKVAAFYPGGFKTNICGSERQWDEQGKEILASIMQETRDDFG
EDYIFKLKNRYNDMIDNSSADISPVLYDMHHALLAKKPNYMYTPGHTLLLLSLFHYFPLW
IYDLVANRLIIKNKQLPCGVLGTCQHKSKDM
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atggaccagctcttcgctgaagctagctttttgcactacttgggggtgagcctcctctta
ggaggagcagtcctgtacaagttaagaaagaaccaggtgcggctagggaagagatgtgcc
tttggtgtgctcttgcttgccctgctggaagtattctgtttcctagcactgcctggtttc
ctagggttgagcctcttcgctctgtcttgtctcatcttttacgtcagcatttctccagga
atgctacctgtggacagcaaagcggtgcttatcacagggtgtgattctggcattggatat
gcactggcaagatatctggatacagtaggcttcaatgtcattgctgctgttttaaataaa
gatggacaaggggctgtggctttgaaaagcagctgttcacagagactttcacttctgcaa
ctggatgtaaccaactctgcacagataaagaaagcctatgaggaagtgaaggcagttcta
cataacaagggattgtggggctttatcaacaatgctggggtgcttggatatgtggtggat
ggcgagttgcttcctatagatatgtacaagaagtgcatggaagtgaatttctttggggct
gtagaagttacaaaaacattctttccactactgcggaaagctcgaggaaggcttattaac
atctgcagcttgggtggatatattccgatgccggggttgtcagcatatggtgcttcaaaa
gctgctctctctatgttttctggagtaatgagacaagaactttccaagtggggtgttaaa
gttgctgcattttatccaggtggtttcaaaacaaatatttgtggatcagagagacaatgg
gatgaacaaggcaaggagatcctggcaagcatcatgcaagaaacaagggacgactttggt
gaagattatatctttaaactgaaaaatcgttacaatgacatgattgataactcttctgca
gacatctctcctgtgctctatgacatgcaccatgctcttttagcaaagaagccaaattac
atgtacacaccaggtcacactttgcttcttctttccctctttcattattttcctctctgg
atttatgacttggttgccaacaggttgattataaaaaacaagcaacttccatgtggagtc
ttagggacctgtcagcataaaagtaaagatatgtag
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