KEGG   Geotrypetes seraphini (Gaboon caecilian): 117359475
Entry
117359475         CDS       T09159                                 
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
gsh  Geotrypetes seraphini (Gaboon caecilian)
Pathway
gsh00562  Inositol phosphate metabolism
gsh01100  Metabolic pathways
gsh04020  Calcium signaling pathway
gsh04070  Phosphatidylinositol signaling system
Module
gsh_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:gsh00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    117359475 (PLCE1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    117359475 (PLCE1)
   04070 Phosphatidylinositol signaling system
    117359475 (PLCE1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:gsh04131]
    117359475 (PLCE1)
Enzymes [BR:gsh01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     117359475 (PLCE1)
Membrane trafficking [BR:gsh04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    117359475 (PLCE1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    117359475 (PLCE1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RasGEF C2 RA EF-hand_like DUF4041 GDPD
Other DBs
NCBI-GeneID: 117359475
NCBI-ProteinID: XP_033798217
UniProt: A0A6P8RB16
LinkDB
Position
4:complement(259163490..259659917)
AA seq 2305 aa
MTSEEMTVSVPAPWARGNMISPPSTRVENSENTLDTSVIKRHRANKGEWTADTVQYLHRL
KEGHFQCTRPNSISSRKVQEGPQNNSNTGLWNRKAYISSSLEYLNINCNIEQEICKSSSL
HNHFCKSCDSLTGEDLCLEPRIPVCQEGAMFAEIQLNMNASSVEMKTSRIQPTENRNSKS
NDNLHFNCASEKAVANTLCTVQPSFILRSSLHAVGSTDCACKLVELPNSSENEKRQHMFN
GCENWRDRSLCLERESERVKMMSCSNHITGKISTKLFPGHFEEYDEDCEEEIEGDLCRSK
KDRSTLLIRRFCKNYREIKKSVYTGTRAIVRALPSGHIGDVAMGFLAWKSKGKSELKYCR
IKSGHSTVVQDLSIRRDFSSCLVKAIWQQVCKAVREKEKAADSFPCFLSPLETVPVSSPF
PSSQDVSSPAKRRVQGFVAEFRATPHRTSVSNFITGALLEATALLGSRSASLNLFGRSAG
RAVLKERQLCGAMAGSNTLPANLAGVSKELVALQHLIQFPEEIASILTEQEQELYRKVLP
FDYLYFLTRDMGNADSQSQLPSIKASLATSLLTSKNGERNTVEGLVTRFNEVSSWVTWLI
LTAGSMEEKREVFSHLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQSDIETMR
SLKDAMAQHESSSEYRKVVNRALHIPGCKVVPFCGVFLKELCEVLDGAASLLRLCPRYNS
QDETLEFVSDYNGQDNFLQRVGKDGLNNADKESTVNNILQIIRSCNRSMESEETDDGFSE
GGSSRKNSFKDRNRYHVTQVKNALESNRVLFIMGDLSDSENDIGEPPKEWDLHGAEEEQK
AFSHGTELIPWYVLSIRTDVHQFLQQGATVIHYDQDAHISSRCFLQLQPDNCTLTWTKLT
TTCLANAKIKPGGPGSSAELSHSRFQFLAGAGASGLVGGFLDLFSVKAVYMGHPGVDMHT
VCVQNKLCNMTLEESGVTLQYGLHTTDNKLLHFVAPKFTAKVLYDGVLELTKAVRKMRKF
PDQRLQWLRKQYVSLYQEDSRFEGPTLAQAVELFGGRRWSTRNTGMGILTKSTEKGNVQR
NNTLGINTAKKKKKVLMRGESGDAADDEMAVRKTKSCKEPRSRSGSDPPDIDEQEDSDQN
TVSSFPTFYTLPSRRTHSLTTYGSPSMISGASSPVRPASSPVLPASNKNQSNTWSSSSWH
GRVKGGMKGFQAFMISDSSMTFIEFVELFKSFSVRSRKDLKELFDVYAVACNRSGSESVP
LYTNLMIDENTTGLQPDLDLLTRNVSDLGLFIRSRQQLSDNQRQISDAIAAASIVTNGTG
VESTSLGVFGMGIQQVNDFLVNCQGEHYTYDEILSIIQKFEPTVSMRQQGIMSFEGFARY
LMDKDNFASKNDESQENLEELQLPLSHYYIESSHNTYLTGHQLKGESSVELYSQVLLQGC
RSVELDCWDGDDGIPIIYHGHTLTTKIPFKDVVEAIDRSAFVNSDLPIIISIENHCSLQQ
QRKMADIFKNVFGDKLITKFLFESDFSDDPMLPSPWQLRGKILLKNKKLKAHQTPVDILK
QKAHQLANMQAQATNGGNTTNITNNNEEEEDEEDEYDYDYESLSDDNILDDRPENKSAID
KLQFEYSEEMPKRIKKSDSTANNKGKVYDMELDEEFYLPQNKKESRQIAPELSDLVIYCQ
AVKFPGLSTLNPCGSSRGKERKCRKSIFGNNPGRMSPGEPTVLTKASGKGVAEARQSWEE
PCSPPFNTSPSLSAIIRTPRCYHISSLNENAAKRLCRRYSQKLIQHTGCQLLRTYPAATR
IDSSNPNPLIFWLHGIQLVALNYQTDDLPMHLNAAMFEANGGCGYVLKPPVLWDKNCPMH
HLFSPLEREMENMEPAIYSLTIISGQNVCPGNSVGSPCIELDLLGMPLDSCHFRTKPVHR
NTLNPMWNEQFLFRVYFEDLAFLRFAVVENNSSAVTAQRIIPLKVLKRGYRHLQLRNLHN
ESLDISSLFINSRRMEENPNGSVLPASLLFSTEERKLTSLYKVTVHGAPGPEPFTVYIVG
GETNAKQLLHQILATGKAKEANAVDGFLIEERCFLPKEKNECRKPPLQRLIGAEEQMGPI
LNSWFPEEGYVGRIILKTREENLSSKNLPEEKDVAQSSEDDNFFVQVHDVSPEQPHTVIR
TARISTAQDVIQQALSKAKYSYSILSNPNPTDYILLEEVSKDPPNKKASTSKTSQRILSD
HECVFQAQSKWKGAGKFILKLKEQVQASRDDKRKGISFANEFKKLTKSSKQSRGVTLPPQ
ATAPDAPQNKDERPTCSLSFNGITE
NT seq 6918 nt   +upstreamnt  +downstreamnt
atgacctctgaagaaatgactgtatcagtgcctgcaccatgggcacgagggaacatgata
tctcctccatcaactagagttgaaaatagtgagaatactttggataccagtgttataaaa
agacatagagcaaataaaggcgagtggactgcagacactgtacagtacttacacagactt
aaggaaggccattttcaatgtacacgacccaacagcatttcatcaagaaaagtacaagaa
ggaccccaaaacaacagtaatacaggcttatggaacaggaaggcctacatctcaagttca
ttggagtatctcaacatcaactgtaatatcgaacaggaaatttgcaagagcagctcactg
cataaccacttctgtaaatcatgtgattctttaactggggaagacctatgtctggaacca
agaattcctgtctgtcaggagggagccatgtttgctgaaattcaattaaacatgaatgca
tcttcagtagagatgaagacatcaagaatccagccaacagagaatcggaacagcaaaagc
aatgacaacttacattttaactgtgccagtgagaaggctgtagctaataccttgtgtact
gtacagcccagttttattttaaggagctctttgcatgcagttggctctacagactgtgct
tgtaagttagtggagctgcccaatagttcagaaaatgaaaaacgacagcacatgtttaat
ggctgtgagaactggagggatcggagtttatgcttggaacgagagtcagaaagagttaaa
atgatgtcatgttcaaatcatatcaccggtaagatctctacaaaactgtttccgggccat
tttgaagaatatgatgaggattgtgaagaggaaatcgagggggatctttgtagaagcaaa
aaagaccgctccaccttattaataaggcgcttttgcaaaaactacagagagattaagaaa
tctgtctatactggaacaagggcgattgtaagagctttgccttctgggcatattggagac
gtagcaatgggttttcttgcatggaagagcaaaggcaaaagtgaactgaaatactgtcgg
attaaatcaggacactcaacagttgtgcaagacttaagcataagacgagatttcagttcc
tgcctggtaaaggccatctggcagcaggtttgcaaggcggtgagagaaaaagagaaggca
gcagactcttttccctgtttcctcagtcctctggaaacagttccagtttcctctccattc
cctagcagccaggatgtaagctctcctgcaaagcgacgtgttcagggctttgtggccgaa
ttccgtgccaccccgcacaggacttcagtttctaatttcatcactggagctttgctagaa
gcaaccgcattgctggggtcaagaagcgcttccctgaatctctttggcaggtcagctgga
agggcagtgcttaaagagcgccagctgtgcggtgccatggccggttccaacaccttacct
gccaatctcgctggagtgagcaaagagctggtggccttgcagcacctgatccagttcccg
gaggagattgccagcattctcacagaacaggagcaagaactctataggaaggtcttgcct
tttgactacctctatttcctaacgagggatatgggaaatgccgattctcagagccagctt
ccaagcatcaaggcgtctttagctacttctcttcttacctctaagaacggtgaacggaat
acagttgaaggccttgtgacccggttcaatgaggtgagctcctgggtgacgtggttgatc
ctgactgcaggctctatggaagaaaaacgagaagtcttctcgcatttggtgcatgtggca
aagtgctgctggaacatgggcaactataatgctgtgatggaattccttgcaggtctcagg
tcaaggaaagttttaaaaatgtggcagtttatggaccagtctgacattgaaaccatgcga
agcttgaaagatgcaatggcacagcatgagtcctcctctgagtataggaaggtggtgaac
cgggctctccatatcccaggctgtaaagtggttcccttctgcggtgtctttctgaaggag
ctctgtgaagtcctcgatggagcagccagtcttctcagactctgtccacgctacaattct
caggatgaaactttagagtttgtttcagattacaatgggcaagacaacttcttgcagcgt
gttggaaaagatggtttaaataatgcggacaaagagtcaacggtgaacaatatcctgcag
atcatccgcagctgtaatcgaagtatggagtccgaagaaacagatgacggcttcagtgaa
gggggcagctcgagaaaaaactcttttaaggacaggaacagatatcatgtgacacaggtt
aagaatgcgcttgagtcaaaccgtgtcttgtttataatgggagatctatcagactctgaa
aatgatataggcgagccaccaaaagaatgggatctgcatggagctgaagaggagcaaaag
gcatttagccatggcacagagctaatcccttggtatgtgttatcgatccgaacggacgtc
catcagtttcttcaacaaggagcgactgtgatccactatgaccaggacgcacacatctcc
tcgcgctgtttcctgcagcttcagcccgataactgcaccttgacctggaccaaactcact
accacctgcctggccaatgccaaaatcaaaccgggtggcccgggaagtagtgccgagctc
agccacagcagatttcagtttctcgccggtgctggtgccagtgggctagtgggaggcttc
ttggatttgttttcggtgaaagctgtttatatgggacatcctggcgttgatatgcacact
gtgtgtgttcagaataaactctgcaatatgactcttgaagagagtggtgtaactctgcaa
tacgggcttcatactactgataacaagctgttgcactttgtggctccaaagtttacagcc
aaagtactgtatgacggagtgttggaactaacgaaagccgtaagaaaaatgaggaagttc
cctgaccagagactgcaatggctgaggaaacaatacgtgagcctgtatcaggaagacagc
aggtttgaaggcccaacactggctcaagctgtggagctgtttggtggcaggcgttggagc
acgagaaacacaggcatggggatcttgaccaagagcaccgagaaaggcaacgttcagaga
aacaacaccttgggaataaacacagccaagaaaaagaaaaaagtactcatgaggggtgaa
agtggagatgctgctgatgatgagatggcagttcgtaaaacaaaaagttgtaaagaaccc
cgaagcagaagtggttctgatccaccagacattgatgaacaggaagattcagatcagaac
actgtgagcagtttccccacattttacactttaccatctagaagaacccactcactcact
acatatggctctccaagtatgatatctggggcatcttcgccagtccgaccagcctcatca
ccagttctgcctgcatccaacaagaaccaatccaatacatggagcagctccagctggcac
ggtcgagttaaaggaggaatgaaggggtttcaggccttcatgatttctgacagcagcatg
acttttattgaatttgttgaactttttaagtctttcagcgtgcggagtcgcaaggacctc
aaggagctgtttgatgtttatgccgtggcttgcaaccgttcaggctcggaatctgttccc
ctctataccaatctgatgattgatgagaacaccactggactgcagccagatttggattta
ttgacgaggaatgtgtctgatttgggattattcattcgaagtagacagcagctgtcggac
aaccaacggcagatatctgatgcaattgctgccgcaagcatagtaaccaacggcaccggc
gtagaaagcacgtcacttggtgtatttggaatgggtatccagcaagtcaatgacttctta
gtgaattgccaaggagaacactacacctatgatgaaatcctcagcattatacagaaattt
gaacctactgtgtctatgcgtcagcaaggaataatgtcctttgaaggatttgccaggtat
ttaatggataaagacaattttgcctcaaaaaatgatgagtcacaggagaatttggaagaa
ttacaactcccgctttcacattattacatcgaatcctcacacaacacatacctcacaggt
caccagctaaaaggagaatcctctgtcgaactgtacagccaggttctcctgcaaggctgt
aggagtgtggaattagactgttgggatggtgatgatggtatcccaatcatttatcatgga
catacacttacaaccaagatcccctttaaggacgtagttgaagctattgatcgcagtgcc
tttgtgaactctgatctgcccatcataatatctatagagaaccactgctcactgcaacag
caacgcaaaatggctgacattttcaagaatgtctttggagataaactgataactaagttt
ttattcgagagtgacttctccgatgatccaatgcttccttccccttggcaacttagagga
aaaatactgctcaaaaacaaaaagcttaaagcacatcagactccagtggatatcctcaaa
caaaaggctcaccagttggccaatatgcaagcacaggccactaatggtggcaataccact
aacatcaccaataataacgaggaggaggaagatgaagaggacgaatatgattatgattac
gaatctctttcagatgacaatattcttgatgatcggcctgagaataaatcagccattgat
aagctgcaatttgaatacagtgaagaaatgcccaagagaattaagaaaagtgacagcact
gctaacaacaaaggaaaggtttatgacatggaactggatgaagagttttatcttccacag
aataagaaggaaagtaggcaaatagcccctgagctttcagatcttgtcatctattgccaa
gcagtgaaatttcctggcctttcaactctaaacccatgtggatccagcagagggaaggaa
agaaaatgcaggaaatccatttttggcaacaatcctggcagaatgagccctggagagccc
acagtactcaccaaagcatctggaaaaggtgtagctgaagcacgacagagctgggaagaa
ccttgttcacctcctttcaacacctctccttccctgagtgccatcattagaacacctcgc
tgctatcacatctcatccctgaatgagaatgctgccaagcgcttatgcagacggtattct
caaaagctgattcagcacactggctgtcagctattgaggacatacccagctgccacacgc
attgattcatccaaccccaatcccctgatattctggctccatggcatacagctcgtggct
ctgaactatcaaacagatgatcttccaatgcatttaaatgccgcaatgtttgaagcgaat
ggtggctgtggctatgttttgaaacctcccgtcctgtgggacaagaattgtccaatgcac
catttattttctccactggagcgagagatggaaaatatggaaccagccatatattcttta
acaatcatctcagggcagaatgtttgcccagggaatagcgtggggagcccctgcattgaa
cttgatctcctcggtatgcctctggacagctgccactttcgcactaaacccgttcatcgc
aataccttgaatcccatgtggaatgaacagttcctcttccgggtttactttgaggatctg
gcctttcttcgctttgctgtggtggaaaataacagttcagcagtgactgcacagagaatc
attcccctgaaggttctcaagagaggatacaggcacctgcagcttcgaaacttgcacaat
gaatccctcgacatctccagcttatttataaacagccgaagaatggaggaaaaccctaat
ggcagtgttctgcccgcctctctgttattcagcacagaggaaagaaagctgacttctcta
tataaagtcacggtgcatggagctcctggccctgaaccttttaccgtctatatcgttggt
ggagagactaatgcaaagcagctccttcatcagattttggcaacaggaaaagcaaaagaa
gcaaatgcagtggacggttttctaatagaagaaagatgttttctaccaaaagaaaagaac
gagtgcagaaagccgccactgcagagactgattggagcagaggagcagatggggccgatc
ctgaacagctggttcccagaggaaggctacgtgggaaggattattttgaaaacgcgagag
gaaaatttgagcagcaagaaccttccagaggaaaaggatgtcgcccagagctctgaagat
gacaatttctttgttcaggtgcacgacgtttccccagagcagcctcacacggtgattagg
acggctcgcattagcactgctcaagatgtcattcagcaggctctcagcaaagccaagtat
tcctacagcatcctaagcaatcccaacccaactgactacatcttgttagaggaagtgagc
aaagaccctccaaacaagaaagcttcaacatctaaaacatcacaacgaattctctcagat
cacgagtgtgtgtttcaggctcagagcaagtggaagggagcagggaaattcatccttaag
ttaaaggagcaggttcaggcatcacgtgatgataaacggaaaggcatttcatttgccaac
gaatttaagaaattaaccaagtcgagtaagcagagtcgaggagtcacgctgccgcctcag
gcaacggcaccagatgctccccagaataaggatgaaaggcctacgtgcagtttgtccttc
aacggtatcactgaataa

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