Geotrypetes seraphini (Gaboon caecilian): 117365887
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Entry
117365887 CDS
T09159
Symbol
HMGCL
Name
(RefSeq) hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1
KO
K01640
hydroxymethylglutaryl-CoA lyase [EC:
4.1.3.4
]
Organism
gsh
Geotrypetes seraphini (Gaboon caecilian)
Pathway
gsh00280
Valine, leucine and isoleucine degradation
gsh00650
Butanoate metabolism
gsh01100
Metabolic pathways
gsh04146
Peroxisome
Module
gsh_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
gsh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
117365887 (HMGCL)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
117365887 (HMGCL)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
117365887 (HMGCL)
Enzymes [BR:
gsh01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.3 Oxo-acid-lyases
4.1.3.4 hydroxymethylglutaryl-CoA lyase
117365887 (HMGCL)
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Motif
Pfam:
HMGL-like
DUF4455
Terminase_2
Motif
Other DBs
NCBI-GeneID:
117365887
NCBI-ProteinID:
XP_033812702
UniProt:
A0A6P8S4K2
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Position
8:complement(28224660..28375203)
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AA seq
386 aa
AA seq
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MEQAQILATLAGERQGQCDDLKAILKSSEERWEANQEAMMRQHGELISTMQDQAKVFSQV
LQKTAIQPGGQTLPAVSVPAPNDISTAGSFPKKVKIVEVGPRDGLQNEKSLVPTDVKIQL
INMLSEAGLPVIEVTSFVSPKWVPQMADQVEVLQGIQIFPGTNYPVLTPNLKGFQAAVAA
GAKEVSIFAAASELFSKKNINCSIDESLQRFQKVVRAAGEANILVRGYVSCVLGCPYEGK
IAPAKVAEVAKAMFSMGCYEISLGDTIGVGTPGGMKEMLSAVMKEIPVEALAVHCHDTYG
QALANILIALQMGVGVVDSSVAGLGGCPYAQGASGNVATEDVVYMLHGLGIHTGVDLKKI
VEAGSFICKALDRRNGSKVSQASCKL
NT seq
1161 nt
NT seq
+upstream
nt +downstream
nt
atggaacaggcccagatactagccacattggccggagagcggcaggggcagtgtgatgac
ctgaaggctatcctgaagtcgagtgaggaacgctgggaggcgaaccaagaggcaatgatg
cggcagcatggggaactgatttccacaatgcaggaccaggccaaagttttttcacaagtt
cttcaaaagactgctatacagcctggaggacagacactaccagctgtatccgttccagct
ccgaatgatatatcgactgctggttcatttccgaagaaggttaagatagttgaagttggc
cctcgggatggattgcaaaatgaaaagtctttagttccaacagatgtaaaaatccagttg
attaacatgctgtcagaagcaggtcttcctgtcatagaagttaccagctttgtatctcca
aagtgggtgcctcagatggcagaccaagttgaagtgttacaaggaattcagatctttcct
ggcacaaattacccagtcctgactccaaatcttaaaggatttcaagcagcggtggcagca
ggtgccaaagaagtatctatctttgcagcagcatctgagcttttcagtaaaaagaacatt
aattgctctattgatgaaagcttacagagatttcaaaaagttgtgagagctgcaggagag
gccaacattcttgtacgagggtatgtttcctgtgttcttgggtgtccctatgaagggaag
attgccccagctaaagttgctgaggtagctaaagcaatgttctcaatgggttgctatgag
atttcccttggtgatactataggtgttgggactcctggtggtatgaaggagatgttgtca
gctgtcatgaaggaaataccagtcgaggcccttgcggttcactgtcacgatacttatggg
caagcccttgctaacatcctgatagctttgcagatgggggttggtgtagtagattcttca
gtcgctggccttggaggctgtccttacgcacaaggagcctcaggaaatgtggccacagag
gatgtggtatacatgttgcatggtcttgggattcacactggagtggatctaaagaagatc
gtagaagctggctcttttatctgcaaagctttggacagaagaaatggctcaaaagtgtct
caagcatcatgcaaactgtaa
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