Gavia stellata (red-throated loon): 104264647 Help Entry 104264647         CDS       T08384                                  Symbol UBR4 Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism gste  Gavia stellata (red-throated loon) Brite KEGG Orthology (KO) [BR:gste00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:gste04121]     104264647 (UBR4) Enzymes [BR:gste01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      104264647 (UBR4) Ubiquitin system [BR:gste04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     104264647 (UBR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  E3_UBR4_N E3_UbLigase_R4 zf-UBR AP3D1 Motif Other DBs NCBI-GeneID:  104264647 NCBI-ProteinID:  XP_009820107 LinkDB All DBs Position Unknown AA seq 5118 aa AA seqDB search ESEILHHDKQYEPFYSSFVALSTHYITTVCGLIPRNQLQSVAAACKVLIEFSLLRLENPD EACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKELASP VSPELRQKEVQMNFLNQLTSVFNPRVSSSPSVMPETQVEGESEDQASTDQTSAAKTKSIF IAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVSANSFFIMPATVADATAVRNGF HSLVIDVTMALDTLSLPVLEPLTPTRLQDVTVLALSCLYAGVSVATCMAILHVGSTQQVR TGSTSSKEEDYENDAATIVQKCLEIYEMIGQAISNSRRAGGEHYQNFQLLGAWCLLNSLF LILNLSPTALADKGKEKDPLAALRVRDIIARTKEGVGSPKLGPGKGHQGFGVLSVVLANH AIKLLSSLFQDLQVEALHKGWESDGPPAVLDIMAQSTSIQRIQRLIDSVPLTNLLLTLLS TSYRKACVLQRQRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGQWFEETI SPSKEKVAPPPPPPPPPLESSPRVKSPNKQTAGENGNILASRKDPELFLSLASNILNFIT SSMLNSRNNFIRNYLSVSLSEQHMATLASIIKEVDKDGLKGTSDEEFAAALYHFNHSLVT SDLQSPTLQNTLLQQLGVAPFSEGPWPLYIHPQSLSVLSRLLLIWQHKATAQGDPDVPEC LKVWERFVGTLKQNALQGTLPSDTEDLNVEHLQLLLLIFHNFSERGRRSIMMLCIQTIVE LTVNMDTQQCSVPLIVARLLLVFDYLLHQYSKAPVYLFEQVQYNLLTPPIGLVSGSQDSS RRTSVPLYHGFKEVEENWTKHCSSDTIPQPRFYCILSLEASEDDLNRLDSTVCEVLFSRT MKYDELYTALTSLLAAGSQFDTLRRKENKNVTALEACALQYYFLILWRILGILPPSKNYM NQLATNTPEMSECDILHTLRWSSRLRIASYVTWIKDHLTKQGMKADHAASLIELASSKCS SVKYDVEIAEEYFARQISSFCGVDCTTILQLHEVPSLQSIYTLDAAISKIQVSLDEHFSK LAAETDPHKSSEITKNLLPATLQLIDTYATFTRSYLLRSLSEEGSTENKPSEEKLRGYAA VLAIGSSRCKSNTLGPTLVQNLPSAVQTLCESWNNIHTNEFPNIGSWRNAFANDTIPAES YISAVQAAHLGTLCSQSLPLAASLKHTLLSLVRLTGDLIVWADDLNPPQVIHSLLPLLLE TSTESVSEISSNSLERILGPAESDEFLARVYEKLITGCYNILAHHSDPNSGLDESILEEC LQHLEKQLESSQARKAMEEFFSESGELVQIMMATANENLSAKFCNKVLKFFTKLFQLTEK SPNPSLLRLCGSLAQLACVEPVRLQAWLTRMTMSPPKDSDQLDVVQENRQLLQLLTTYIV RENSQVGEGVCTVLLSTLIPMATEMLANGDGTGFPELMVVMATLASAGQGAGHLQLHGAA VDWLGRCKKYLSQKNVVEKMNANVMQGKHVTILECTCHIVSYLADVTNALSQTSGQGPSH LSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCH TCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSSTM KESAFQSEPRVPESVIRHASTSPAEKSKVTISEGKGPDEEKPKKSSLCRNVEGCREELQS QANFSFAPLVLEMLNFLMDAIQINFQQASAMGSSSRAQQALNELHTLDKSVEMTDQLMVP TLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKI TVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFS SSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLSVDALSPTFYFLL PSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQHGPFYVTNVLEVNHEDLKD SNGQVAGGGVSVYYSHVLQMLFFSYCQGKSFAATISRANLEVQRLFPINIKSSNGGSKTS PALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTA CNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKAAAITTRT SSQVNFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEVT NNNSTMVMTGMRIQIGTQAIERAPSYLEIFGRTMQLNMTRARWFDFPFTREEALQADKKL TIFIGASVDPAGVTMMDSIKIYGKTKEQFGWPDEPPEDFPSASVSNVCPPNLNQGNGTGD TESATPAAASGTVLERLVVSSLEALESCFAVGPVNEKEKNKVAAQELATMLLSMPAPSSV QQQTKSLLASLHTSRSAYHNHKDQALLSKAIQYLSSSTKEGKDLDPEVFQRLVITARSIA IMRPNNLVHYTESKLPQLETENEEGQEAQKHAEGDGCTFITQLVNHFWKLHASKPKNAFL APACLPGLTHVEATVNALVDIIHGYCTCELDCIHTASKIYMQMLLCPDPAVSFSCKQALI RVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDAEDKLQSSGIANGEHIRQESQEQSEV DHGDFEMVSESMVLETSENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIAL SLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTASAPASDDEGSTAATDGSTL RTSPAEHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDTAAEGHPAGPGSVSSSTGAIST TTGQQEGDGSEGEGEAEGDVHTSNRLHMVRLMLLERLLQNLPQLRNVGGVRAIPYMQVIL MLTTDLDGDDEKDKGALDNLLSQLIAELCMDKKDVSKKNERSPVNEVHLVVMRLLSVFMS RTKSGSKSSICESSSLISSATAAALLSSGAVDYCLHVLKSLLEYWKSQQNDEEPVATSQL LKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTNSRIPPP VFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKDKYRQLRDLHTLDSHVRGIKKLL EEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIATQRTVNWQKFCIKDDSVLYFL LQVSFLVDEGVSPVLLQLLSCALCGSKVLSVASSSGSSSTSSTSAPAASGSGQSATQSKS STKKSKKEEKEKEREGESSGSQEDQLCTALVNQLNKFADKETLIQFLRCFLLESNSSSVR WQAHCLALHIYRNSNKSQQELLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLKTQQTEKK LKEYSQKAVEILRTQNHILTNHPNSNIYNTLSGLVEFDGYYLESDPCLVCNNPEVPFCYI KLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVEL KNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSA SVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDP IENEEDRKKAVTNINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQDESSSSGGI SSTSASVNRYILQLAQEYCGDCKNSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRT TVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNSAIRHILVSQGL IRELFDYNLRRGAATMREEVRQLMCLLTRDNPEATQQMNDLIIGKVSAALKGHWANPDLA SSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIK PPAPTSKKNKDVPVDALTTVKPYSNEIHAQAQLWLKRDPKASYEAWKKCLPARGIDANGK SPSKAELHQLYLSEKYVWKWKQFMSRRGKRTCPLDLKLGHNNWLRQVLFTPATQAARQAA CTIVEALATIPSRKQQVLDLLTSYLDELSIAGECAAEYLALYQKLIKPAHWKVYLAARGV LPYIGSLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGT VLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYSLDDY RTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRD IKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCPTNEGEPMRIIYRMR GLLGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLTGIKDFKQGRHLL TVLLKLFSYCVKVKINRQQLVKPEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSI MEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNLSVLQGLLRIIPYLSF GEMEKMQILVDRFKPYCNFDKYDEEHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQK GITQNALDYMKKHIPSAKNLDADIWKKFLSRPALPFILRLLRGLATQHPATQVLIGTDSI TNLHKLEQVSSDEGIGTLAENLLEALREHPEVNKKIDAARKETRAEKKRMAMAMRQKALG TLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALE EFENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGP HVPESAFATCLARHNTYLQECTGQREPTYQLNVHDIKLLFLRFAMEQSFSVDTGGGGRES NIHLIPYIIHTVLYVLNTTRATSREEKNLQSFMEHPKEKWVESAYEVDGPHYYIVLALHI SPPEKWKAMRVEILKRLLVTSHARVVSPGGASRLADKTVKEYATYRSGLLFWALVDLIYN MFKKVPTSNTEGGWSYSLAEFIRHNDMPIHEAADKALKTFQEEFMPVETFSEFLDVAGLL SEINDPDSFLKDLLNSIP NT seq 15358 nt NT seq  +upstreamnt  +downstreamnt tgaatctgaaatcctgcaccatgacaaacaatatgagcctttttactcttccttcgttgc actttctacacattacatcactactgtgtgtggtctaataccaagaaaccaattgcaatc agtggcagctgcttgtaaagtcctgattgaattctcactgctgcgtcttgagaatccaga cgaagcctgtgctgtttcccagaaacacctcattctgctgataaaggggctgtgcacggg ctgcagccgcctggatcgaactgaaattattaccttcacagcaatgatgaaatcggccaa gctgcctcagactgtcaaaaccctctctgatgtagaggaccagaaggagctggcctcccc ggtgagcccggaactaagacagaaagaagtgcagatgaacttcctcaatcagttgacatc agtctttaaccctagagtctcgtcatcgccatctgtcatgccagagacacaggtggaagg agagagcgaggatcaagcttccacagatcaaacctctgcggcaaagacaaaaagcatatt cattgctcagaatgtagccagcttgcaagaacttggtggctctgaaaaactgctgagagt gtgcttgaacctcccatacttcttgcgatacataaatcgatttcaggatgcggtgtcagc caactccttttttattatgccagccacggtggcagatgccactgctgttcgcaatggatt tcattcgctggtgatagatgtgaccatggcactggatactctgtctctgcctgtattgga gcccctgacacccacgcgtctccaagatgtgactgttcttgctctcagctgtctctatgc aggtgtgagtgtggcaacttgcatggccatcctacatgtgggtagcactcagcaggtacg aactgggtcaacaagttccaaagaagaagattatgaaaatgatgctgctactattgtaca gaaatgtcttgaaatttatgaaatgattggacaagccatcagcaattcacgccgtgcagg gggtgagcattatcagaacttccagctgctcggggcttggtgtttgctaaacagcctctt cctcatcttgaacctcagccccacggccttggctgataagggaaaggagaaagatccgtt ggctgctcttcgtgtcagagacattattgctcgtactaaggaaggcgttgggtctcccaa actaggacctgggaaagggcatcaagggtttggtgttctgtcagtggtgctagcaaatca tgctatcaaattgctgtcatcgctctttcaagatctgcaagtggaggcattgcacaaggg ctgggagagtgatggtccgccagcagtgctggatatcatggctcaaagcacatccatcca gagaattcagcggctaatagattctgtaccactcactaatttgctgctgactttgctatc tacttcctacagaaaggcttgtgtcttgcagcgtcagaggaagggctccatgagcagtga cgcaagtgcctccactgattctaatacttactatgaggatgattttagcagcactgagga ggacagcagccaagatgacgacagtgaaccaatccttgggcaatggtttgaagagacaat ctctccaagcaaagagaaagtggccccaccgccaccccctccaccaccacctttggagag ctcgcctagagtgaaaagccctaacaaacagactgctggggagaacgggaacatcctggc tagccgcaaagatccagaattgtttttgagcctagcttcaaacattttgaactttatcac ttcttctatgctgaactccaggaataacttcattcgcaactacctgagtgtgtctctttc ggagcagcacatggctacactggctagcatcatcaaagaagtggataaggacgggcttaa gggcacgtcagatgaggagtttgctgctgcactgtatcacttcaaccattccctggtcac ctcagatcttcagtcccctaccttgcagaacacgcttcttcagcagctgggagttgcccc tttttctgaaggtccgtggcctctctacatccatcctcaaagtttgtcagtgctctcgcg acttctcctgatttggcagcataaagccactgcccagggagatcctgacgttccagaatg ccttaaagtttgggagaggtttgtgggcacactgaagcaaaatgccttgcaggggactct tcccagtgacacagaagatctgaatgttgaacatctccagttgttgctgcttatttttca caatttctctgagaggggccgcagatctatcatgatgctctgtatccagacaattgtgga gctgacagtgaacatggatacccagcaatgttctgtgccgcttatcgtggcacgtctact cttggtgtttgactacctgctccatcagtattccaaggctcccgtgtacctatttgaaca ggtgcaatataatttgctgactccacccattggcttggtgagtggatcccaggacagtag cagacgaacgtctgtcccactttatcatgggtttaaagaagtggaagaaaactggactaa acactgttcatcagacacaattccccagccgaggttctactgcatcctatctctagaagc ttctgaagatgatctgaaccgtctagatagcacggtttgtgaggtccttttctctaggac catgaagtatgatgagctttacacagccctgacttcgttacttgcagctgggtcacagtt tgatacactcaggaggaaagagaacaaaaatgtcactgcactggaagcctgtgcacttca gtactacttcttgatactgtggcggatactagggattttgcctccatccaaaaactacat gaatcaattggctacgaacacaccagagatgagtgaatgtgatattttgcacacattgcg ctggtcttcccgtctgagaattgcgtcttatgtcacgtggatcaaggatcacctaaccaa gcagggcatgaaagctgaccatgctgcttctctcattgaattggcctccagcaagtgcag ctcagtgaagtatgatgtggaaatagcagaggaatacttcgctcgacagatatcttcttt ctgtggtgttgattgcacaactattctccaactgcatgaagttcccagtttacaatccat ttacacccttgatgctgcaatttccaagattcaagtttctctagatgagcacttttccaa gctagctgcagaaactgatccacacaagtcttctgagataaccaagaacctcctgcctgc tacgctgcagcttattgacacttacgctacgtttaccagatcttacttgctgcggagcct ctctgaagagggctccactgagaataaaccctctgaagagaagctacgaggttatgctgc tgtcctggccattggatccagtcgttgcaagtctaataccctaggtccaacacttgttca gaacttgccatcagctgtgcagactttatgtgaatcatggaacaacattcatacaaacga gtttccaaacattggctcatggcgcaatgcctttgcaaatgacacgatccctgcagaaag ctacatcagtgcagttcaggccgcccacctcggtactctctgcagccaaagtctacctct cgcagcctccctaaaacacacccttctctccctggtcagactcactggggatctcattgt ctgggcagatgatttgaacccaccgcaggtgattcattccctattgcccctccttttgga gaccagcacagagagtgtgtcagagataagcagcaactccctagaaaggatcttgggccc tgcagaatcagatgaattcctggcacgtgtttatgagaaattgatcacaggatgctataa catactggcccatcactctgatccaaacagtggcctggatgagtccatcttggaggaatg tttgcagcatctggagaaacagctggagagcagccaggcccgaaaagccatggaggaatt cttttcagaaagtggagaactggtccagatcatgatggcgacagccaatgaaaacctctc agcgaagttctgtaacaaggtgctgaaattcttcaccaagctcttccagctaactgagaa gagtcccaaccccagcctgttgcgactttgtggctctttggctcagctggcttgtgtgga gcctgtccgtctccaggcctggttaaccaggatgaccatgtccccacccaaagattcgga tcaactggatgttgttcaagagaacaggcaactgctgcaactcttgacaacttacattgt tcgggaaaacagccaagttggagaaggcgtgtgcactgttctgctgagtactctgatacc aatggcaacagaaatgttggccaatggtgatggcacaggctttcctgaactgatggtcgt gatggcaactttggctagtgcaggacaaggtgcgggacacctccagcttcatggtgctgc tgttgactggctaggcagatgcaagaaatacctgtctcagaagaatgtggtagaaaaaat gaatgcaaatgtcatgcaagggaagcatgtgactatcctggagtgtacatgccatattgt ctcttacctggccgacgtcactaatgcactgagccagaccagtggccaaggaccaagtca tctttctgttgatggagaggaacgggcaattgaggtggattcggactgggtggaagagtt ggcagtggaggaggaggactctcaagctgaagattcggatgaagattctctttgtaataa actctgtaccttcaccatcacacagaaagaattcatgaatcagcattggtatcactgtca cacttgcaagatggttgatggggttggtgtttgcacagtttgtgctaaagtttgtcacaa ggatcatgagatttcttatgccaaatacggatcattcttctgtgactgtggagccaagga agatggcagttgcctggctttggtgaagagaactcccagcagtggtatgagctctaccat gaaagaatccgccttccagagtgagcccagagtgcccgagagtgtcattcgacatgcaag cacctctcctgcagagaaatccaaggtcaccatcagtgagggaaagggccctgatgaaga aaaacccaagaagagcagcctgtgtagaaatgttgagggctgtcgagaggaattgcagtc ccaggccaacttctcctttgcacctttggtgctggagatgctgaatttcctgatggatgc cattcagataaacttccagcaagcttcagccatggggagcagcagtcgtgcacagcaagc tctcaatgagctgcatactttggacaagtcagtagaaatgacagatcagttgatggtccc aactcttggctctcaagaaggtgcttttgagaacgtccgcatgaactacagtggtgacca gggccagacgatccggcaactgatcagcgctcatgtgctgaggcgggtggcgatgtgtgt gctgtcgtccccgcatggacgtcggcagcacctggctgtcagtcacgaaaagggcaagat tacagtccttcagctctcagcattgctgaagcaagcagactctagcaaaagaaaattgac ccttactcgccttgcatctgcacccgttccatttactgtactgagcctaactggaaatcc ctgcaaggaggactacctagccgtgtgtggactgaaagactgccacgtgttaacattcag cagctctggatcagtctctgatcatttggtacttcatccccaactagccactggaaattt catcattaaagctgtctggctgccaggatctcaaacagagcttgctattgtgactgcaga ctttgtgaagatttacgatctctctgtagatgccttgagtccaactttctatttccttct accgagttccaaaatcagggatgtcactttccttttcaatgaggaggggaagaacataat agtgatcatgtcctccgctgggtacatctatacgcagctcatggaagaggcaagcagtgc ccagcatggaccattctatgtcaccaatgtgcttgaagtcaatcatgaggacttaaagga cagcaatggccaggtagcaggaggtggtgtgtcagtgtattactcccatgtgctacagat gttgttcttcagttactgtcaaggcaaatcctttgcagccaccatcagccgcgccaatct ggaagtgcagcggctattcccaattaacataaagagttcaaatggtgggagtaagacttc gccggcactctgtcagtggtctgaggtgatgaaccaccctggcttggtgtgctgtgttca acaaaccacaggtgtcccgctggtggtgatggtgaagccagacacctttctcatccagga gattaaaaccttgccagccaaagcaaaaattcaggacatggtggccatccgtcacacagc ctgcaacgagcagcagaggaccactatgatcctcctgtgcgaagacggcagcctgaggat ctacatggccaatgtagagaatacctcctactggctccagccctctctccagcctagcag cgtcatcagcattatgaagccggttcgcaagcgcaaggcagctgctattacaactcgcac atctagccaagtgaacttccctattgacttctttgaacacaaccagcaactcacagatgt agagtttggaggcaatgacctgctgcaggtttacaatgctcagcagataaagcaccggct caattccactggcatgtatgtggccaacacaaagcctgggggtttcaccattgaagtgac gaacaataacagcacgatggtgatgacaggcatgcggatccagattggcacacaagcgat agagagagcaccctcgtacttggagatctttggccgcaccatgcagctgaacatgaccag ggctcgttggtttgacttccctttcactcgcgaggaagccttgcaggctgacaaaaaact aaccatcttcattggggcttctgtggatcctgctggagtcacaatgatggattccataaa aatttatggcaaaaccaaagagcagtttggatggcctgatgagccccccgaggatttccc atctgcttcagtgagcaatgtttgtcccccaaacctgaaccaagggaatggcactggaga cacggagtcggctacccctgctgctgctagcgggactgtcctggagaggctagtagtgag ttctttagaagcgctggaaagctgctttgctgtaggaccagtcaacgagaaggagaagaa taaagtggcagcccaggaactggctactatgctgctgtccatgccagctccttccagcgt ccagcagcaaaccaagagcctcttggctagcttgcacaccagccgctcagcgtaccataa ccacaaggatcaagcattgttaagtaaagccattcagtatttgagttcttcaaccaaaga aggaaaggaccttgatcctgaagtgtttcagaggctggtcatcactgctcgatccattgc tattatgagacccaacaatctagtccattacacggaatcaaagctgccacagttggaaac agagaatgaagaagggcaagaggcccagaaacatgctgaaggagatggctgcacatttat tacccagctggttaaccacttctggaagctacatgcatcaaaacccaaaaacgccttcct tgcccctgcctgcttgccaggtctcactcatgttgaagccacagtcaatgctttggtgga tattatccatggatactgcacgtgtgaactggattgtatccatacagcatccaagatcta catgcagatgttactttgcccggatcctgcagtgagcttttcctgcaaacaagctttgat cagagtgctgagaccaaggaacaagcggagacatgtcaccttgccatcctcccctcggag caatactcctatgggggataaggatgatgatgatgatgacgatgcggaagacaagctgca gagttctgggatagcaaatggcgagcatatccgacaagaaagccaggagcaaagcgaagt tgatcatggggacttcgagatggtgtctgaatctatggttctggagacttctgaaaatgt gaataatgggaacccttctcccctggaggctcttctggctggagcagaaggattccctcc tatgctggatattcctccagatgcagatgatgaaacaatggtggaattggctattgccct aagcctgcaacaagatcagcaagggagcagcagtagtgcacttggacttcagagcttagg actgtctggccaagcacccagctcttcttctcttgatgccggaacgctctcagatacaac agcatcagctccagcgtctgatgatgaaggcagcacagctgccacagatggctcaactct tcggacttcacctgcagagcatggtgggagcgtgggctctgagagcggtggcagcgcggt ggactccgtagctggtgagcacagtgtgtctggccgtagcagtgcctacggggacacggc agctgagggccaccctgctggacctggcagcgtcagctcaagcacaggcgctatcagcac tactacaggccagcaagagggagatggttcagaaggggaaggggaggcagagggagatgt ccacaccagcaacaggctgcacatggtccgactgatgttgttggagaggctgctgcaaaa cttacctcagctgaggaatgttggaggagtccgggccattccttatatgcaggttattct gatgctcacaacagacctagatggagatgatgagaaagacaagggagctttagataacct tctgtcccaactgattgcagaactgtgcatggacaaaaaggatgtgtctaagaaaaatga acgctctcctgtgaacgaagtgcacttggtggtaatgaggctgcttagtgtgttcatgtc cagaactaagtcaggatccaagtcttccatttgtgagtcttcctccctcatctctagtgc caccgctgctgcgttgttgagctctggtgctgttgactactgtctgcatgtgctgaagtc tttgctagagtactggaaaagccagcagaatgacgaggagcctgtagccaccagccagct cctgaaacctcacactacttcttctccacctgacatgagcccttttttcctccgccagta tgtgaagggtcatgctgcagatgtttttgaggcctacactcagctcctgacagagatggt actgcggctgccctatcagatcaagaagatagcagacacaaactcccgcatcccacctcc tgtctttgatcactcctggttctactttttgtctgagtacctgatgatccagcagactcc attcgtgcgccgccaagtccgcaagcttttgctctttatctgtggatcaaaggataaata ccggcagctcagagaccttcacacgttggattctcatgttcgtggaatcaaaaagctcct agaagagcaaggcattttccttcgtgccagtgtggtcacagcaagttcaggctctgccct gcagtatgatacattgatcagcttgatggaacatttaaaggcttgtgcagagatcgccac acagcgaacagtaaactggcagaaattctgcattaaagatgactcggttctctatttcct ccttcaagtcagcttcctagtagatgaaggagtgtcaccagttcttctgcagctgctgtc ttgtgctctgtgtggcagtaaagtgctgtctgtggcttcatcctccggatcatcaagtac ctcttccacctctgctcctgcagcatcgggctctgggcagtcagcaacacagagcaaatc ctccactaaaaagagcaagaaagaagaaaaggaaaaggagcgagagggtgagagttcggg cagtcaggaagatcagctgtgtacagctctggtgaaccagctgaacaagtttgctgataa ggagaccctcattcagttcctgcgttgcttcttgctggagtccaactcgtcctctgtgag atggcaggcccactgcctcgcactccacatctacaggaactctaacaagtctcagcagga gttactgttggatctcatgtggtcaatctggccagaacttccagcctatggaagaaaggc tgcccagtttgtagatctcctgggatacttctctctgaaaacacagcagactgagaaaaa gttgaaggaatactcccaaaaggccgtggagatcctccggactcaaaaccacattcttac caaccaccctaactccaacatttacaacacgctgtctgggctggtggaatttgatggcta ttacctggagagcgatccctgccttgtctgcaacaatccggaggtgcccttctgttacat caagctttcctccataaaagtggacacgcggtatactaccacccagcaagtggtgaaact aatcggcagccacaccatcagcaaagtgacagtgaagataggagacctgaaacgaaccaa aatggtccgaaccatcaacctctattacaacaacaggacagtgcaagccatagtggagct gaaaaacaagccggctcgttggcacaaagctaaaaaagtccagctgaccccaggccagac ggaggtgaagattgatttgccgctgcccattgtggcttcgaacctgatgattgaatttgc agatttctatgagaattaccaggcttccacagagaccctgcagtgcccccggtgtagcgc gtccgtcccagccaacccgggggtgtgtgggaactgcggcgaaaatgtgtaccagtgcca caagtgcagatccattaattatgatgagaaagatccattcctttgcaatgcctgtgggtt ctgtaaatacgctcgctttgacttcatgttgtatgccaagccttgctgtgcagtggatcc catagagaatgaagaggatcgaaagaaggcagtaacaaatatcaacactctcctggacaa ggctgacagagtgtaccaccagctaatggggcaccgaccgcagctggaaaaccttctgtg taaagtgaatgaggcggctcctgaaaagccacaggatgaatctagtagtagtggagggat aagttctacctcagctagtgtgaatagatacatactccagttagcccaggagtattgtgg cgactgcaagaactctttcgatgagctttccaaaatcatccagaaagtgtttgcctctcg aaaggaactcctggaatatgatctccaacagagagaggcagcgacgaagtcctcgcgaac cactgtccagcccacatttactgccagccagtatcgtgccttgtctgttttaggctgtgg ccacacatcatcaactaaatgctatggctgtgcctcagccgtcactgaacactgcataac gttgctgcgagctttggcaaccaactctgccatcaggcatatccttgtgtcccagggcct tatccgagagctctttgactacaacttgcgccggggcgcagccactatgcgggaggaggt ccgtcagctcatgtgccttctgaccagggacaatccagaggccacacaacaaatgaatga cttaatcattgggaaggtttctgcagctttgaagggacactgggcaaatccagacttggc tagcagcctacagtatgaaatgttgctgctaacagattcgatctcgaaggaagacagctg ctgggagctccgactacgttgtgctctcagcctctttctgatggcagtaaacattaagac tccagtggttgttgaaaacatcaccctcatgtgcctgcgcattcttcaaaagctgatcaa gccacctgctccaaccagcaagaaaaacaaggatgtgcctgtggatgctctcaccactgt gaagccttacagcaatgaaatccatgcacaagctcagctgtggctcaagagggaccccaa agcatcgtatgaagcttggaagaagtgcctccctgccagaggtatagatgccaatgggaa atctcccagcaaagctgagcttcaccagctctacttgtcagaaaaatatgtctggaaatg gaaacagttcatgagtcgccgtgggaagagaacttgccctctggatctcaagctgggaca caacaattggctgcgacaggtgctgtttactcctgccactcaagctgcaaggcaagctgc atgtactattgtggaagctctggctaccatccccagccgcaaacagcaggtccttgatct cctgacgagctacctggatgagctgagcattgctggcgagtgtgccgccgagtacctggc actgtatcagaagctcatcaaaccggcgcactggaaggtctacctggcagccaggggggt tctgccctatatcggcagcctcatcactaaggaaatagctcgtttacttgccttggagga agcaacactcagcactgatttgcagcagggatatgccttgaagagtcttacaggtcttct ctcttccttcgtggaggtggagtccatcaaacggcacttcaaaagccgtctggtgggtac agtcctgaatggttacctgtgtttgaggaagttagtggtacagagaacaaagctgatcga tgaaacgcaggacatgctgctggagatgctggaggatatgacaacaggcacagaatctga aaccaaagcatttatggcagtgtgtatagagactgcaaaacgttacagccttgatgacta caggactccagttttcatctttgagagactatgcagtattatctatcctgaagagaatga agtgacagagttctttgtaactctggagaaagatccccagcaggaagacttcttacaggg cagaatgccaggaaatccctacagcagtaatgagcctggcattgggccactcatgaggga catcaagaacaaaatctgtcaggactgtgacctggtagctctgctggaggatgacagtgg aatggagcttttggtgaacaataagatcatcagtttggatctgcctgtggctgaggtcta caagaaggtgtggtgtcccactaatgagggggagccgatgaggatcatttaccgcatgcg ggggttactaggagatgcaactgaggaattcatcgagtctctcgactccactactgatga agaggaggatgaggaagaagtttataagatggcaggtgtcatggcccagtgtggaggctt ggagtgcatgctcaacagactgactggaatcaaagacttcaaacaaggccggcacctctt aaccgtgctgttaaaactgtttagttactgtgtgaaggtgaaaataaatcgtcagcagtt ggtcaagccggagatgaacactttgaatgtcatgctgggaactcttaacttggctctggt ggctgagcaggaaagtaaggacagcggaggagcggctgtggccgaacaagtgcttagtat aatggagatcatactggatgaatccaacgcagaacctctgagcgaggacaagggtaacct cctcctaactggtgacaaagatcagctggtaatgttgctcgatcagattaacagcacttt tgtccgttccaatctcagcgtcttgcaaggcctattacgcatcattccttacttgtcctt cggggaaatggagaaaatgcagattctggttgatcgattcaagccgtactgtaactttga taagtatgatgaggagcacagtggagatgataaagttttcctagactgcttctgtaaaat agcagcgggaataaagaacaacagcaacggccatcagctgaaagatcttatccttcagaa gggaattacacagaatgcccttgactacatgaaaaagcacattcccagtgcaaaaaattt ggatgcagacatatggaagaaattcttatctcgacctgcacttccttttatcctgcgcct gctccgtggacttgccacacagcaccctgctacacaggtgctaataggtacagactcgat taccaacctgcataaactggagcaggtgtctagtgatgaagggattgggacattagcgga gaatcttctggaggcactaagggaacatccagaggtgaataagaagattgatgctgcccg gaaggagacgcgtgcagagaagaagcgtatggccatggcaatgagacagaaggccttggg cactctggggatgacgacaaatgagaagggtcaggtagtgaccaagactgcgctgcttaa acagatggaggaacttatagaagaaccaggtctgacttgctgcatctgccgggaaggata caagtttcagcctacaaaagtcctaggtatttatactttcaccaaacgagttgcactaga ggagtttgagaacaagccccgaaaacaacagggatacagcacagtctctcacttcaacat tgtccactacgattgtcacctcgcagctgtaagacttgcccgtggccgtgaagaatggga gagtgcagccctacaaaatgccaacaccaaatgtaatgggctcctgccagtctggggacc tcatgtgccagagtctgcttttgctacttgtttagcacgacacaacacgtacctccagga atgcacagggcagcgggaacccacctaccagctcaatgtccatgacattaaactgctgtt tctccggtttgcgatggagcaatcgttcagcgtagatactggaggaggaggaagggagag caatatacacctcattccatacataatccacacggtgctctacgtcctcaacacaactcg agcaacttcgagggaggagaaaaacctgcagagcttcatggagcaccccaaagagaagtg ggtggagagtgcctacgaggtggacgggccccattattacatcgtgctggcgctgcacat ctcgccccccgagaagtggaaagccatgcgagtggagatcctcaagaggctcctcgtcac ctcccacgcgcgagtggtgtccccagggggagccagcagactggcagataagacagtgaa ggaatacgcaacgtaccgctctggccttctcttctgggccctagtagatctcatttacaa catgttcaagaaggtgcctaccagtaacacagagggaggctggtcctactctcttgctga attcatacgacacaatgacatgccaatacacgaagctgcagacaaggccctgaaaacctt ccaggaggagttcatgccagttgaaacgttttctgagtttttggatgtggctggactctt atcagaaatcaatgatcccgacagcttcctcaaggatcttttgaactccatcccctga

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