Geobacillus thermoleovorans CCB_US3_UF5: GTCCBUS3UF5_2420
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Entry
GTCCBUS3UF5_2420 CDS
T01676
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
gte
Geobacillus thermoleovorans CCB_US3_UF5
Pathway
gte00300
Lysine biosynthesis
gte00550
Peptidoglycan biosynthesis
gte01100
Metabolic pathways
gte01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
gte00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GTCCBUS3UF5_2420
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GTCCBUS3UF5_2420
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GTCCBUS3UF5_2420
Enzymes [BR:
gte01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GTCCBUS3UF5_2420
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEV17568
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Position
235037..236413
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AA seq
458 aa
AA seq
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MIKRTVRQIAEMADGQCLKPEWENMVVSGVSTDTRTIQAGNLYVPLRGATFNGHDFVQEA
VQKGAAAVLWAEREGTPPEGVPVVVVDDTLLALQRLAARYREQLGMKVIGVTGSNGKTTT
KDMIAALLATNYRVQKTEGNFNNHIGVPLTLLSLDEGTEMAVVEMGMSGFGEIERLTMIA
RPDAAVITNIGEAHLQELGSREGIAKAKLEILAGLHHDGLFVYHGDEPLLTERVPKLPLP
RHVVTFGAGEQNDYYPTDVRIEAGGTSFVINALPGRTLFMPVLGKHHVYNALAAIAVARF
FGIDWEGIDASLSRLQVTRMRTEVVKTKYGFTVINDAYNASPTSMRAALTLLGELGGYRQ
KIAVLGDMLELGDEEVAFHREIGEVLRPGMVDYVFTYGPLAHHIAAAAAPFFDDGRVRAF
DDKAALAEAVRSVASPEDIVLLKASRGMKLEELLRYWV
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgatcaaacggacagtgcggcaaatcgccgaaatggctgacggacagtgtttaaagccg
gaatgggagaatatggtcgtaagcggtgtgtcaaccgacacaaggacgatccaagccggc
aacttgtacgttccgttgcgcggtgcgacctttaacggccacgatttcgtgcaagaagcg
gtgcaaaaaggagccgccgccgtactgtgggcggaaagggaaggaacgccgccggaaggt
gtgccagtggtcgttgtggatgatacgcttttggcattgcagcggctcgccgcccgctac
cgcgagcagcttggaatgaaggtgatcggcgtcactggcagcaacggcaaaacgacgacg
aaagatatgattgccgcgctgctggcgaccaactaccgcgtgcaaaaaacagaagggaac
ttcaacaaccatatcggtgtgccgttgacgcttctttcgcttgacgaagggacggagatg
gctgttgtcgaaatggggatgagcgggtttggcgaaatcgagcggctgaccatgatcgcc
cgtccggacgcagcggtcatcacgaatatcggagaagcacacttgcaggagctcgggtcg
cgggaaggcatcgccaaggcgaagttggaaattttggcgggtttgcaccatgatggttta
ttcgtctaccacggcgatgagccgctcttgacggagcgcgtgccgaagttgccgcttccc
cgccatgtcgtgacgttcggggcgggcgaacagaacgattactatccgaccgatgtgcgc
attgaagcgggaggaacatcgtttgtcatcaatgcgctccccggccggacgctgtttatg
ccggtattaggcaagcatcatgtgtacaacgcgctcgccgccattgcggtcgcccgcttt
ttcggcatcgattgggaaggcattgatgcgtctctctcccgcctgcaagtgacgcgcatg
cgtacggaagtcgtcaagacgaaatatggctttaccgtcattaatgatgcctacaatgct
agcccgacatcgatgcgcgccgccttgacgctgcttggggaattgggcggctaccggcaa
aaaatcgccgtattgggcgatatgttagagcttggtgacgaagaagtggcgtttcatcga
gagatcggggaggtgttgcggccgggaatggtggactatgtgttcacttacgggccgctg
gcgcaccatatcgccgcggcggctgccccattttttgatgatgggcgggtgagggcgttc
gacgataaagcagcgttggccgaggccgtgcgttccgtcgcgtctccggaggacatcgtc
ttattgaaagcatcgcgcggcatgaaattggaagagttgcttcgatattgggtgtaa
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