Geobacillus thermoleovorans KCTC 3570: GT3570_01140
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Entry
GT3570_01140 CDS
T04710
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
gtk
Geobacillus thermoleovorans KCTC 3570
Pathway
gtk00300
Lysine biosynthesis
gtk00550
Peptidoglycan biosynthesis
gtk01100
Metabolic pathways
gtk01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
gtk00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GT3570_01140
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GT3570_01140
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GT3570_01140
Enzymes [BR:
gtk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GT3570_01140
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AMV09595
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Position
203476..204852
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AA seq
458 aa
AA seq
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MIKRTVRQIAEMADGQCLKPEWENMVVSGVSTDTRTIQAGNLYVPLRGATFNGHDFVQEA
VQKGAAAVLWAEREGTPPEGVPVVVVDDTLLALQRLAARYREQLGMKVIGVTGSNGKTTT
KDMIAALLSTHYRVQKTEGNLNNHIGVPLTLLSLDEGTEMAVVEMGMSGFGEIERLTMIA
RPDAAVITNIGEAHLQELGSREGIAKAKLEILAGLHHDGLFVYHGDEPLLTERVPKLLLP
RHVVTFGAGEQNDYYPTDVRIEAGGTSFVINALPGRTLFMPVLGKHHVYNALAAIAVARF
FGIDWEGIDASLSRLQVTRMRTEVVKTKCGFTVINDAYNASPTSMRAALTLLGELGGYRQ
KIAVLGDMLELGDEEVAFHREIGEVLRPGMVDYVFTYGPLAHHIAAAAAPFFDDGRVREF
DDKAALAEAVRSVATSDDIVLLKASRGMKLEELLRYWV
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgatcaaacggacagtgcggcaaatcgccgaaatggctgacggacagtgtttaaagccg
gaatgggagaatatggtcgtaagcggtgtgtcaaccgacacaaggacgatccaagccggc
aacttgtacgttccgttgcgcggtgcgacctttaacggccacgatttcgtgcaagaagcg
gtgcaaaaaggagccgccgccgtactgtgggcggaaagggaaggaacgccgccggaaggt
gtgccagtggtcgttgtggatgatacgcttttggcattgcagcggctcgccgcccgctac
cgcgagcagcttggaatgaaggtgatcggcgtcactggcagcaacggcaaaacgacgacg
aaagatatgattgccgcgctgctttcaacccactatcgagtgcaaaagaccgaagggaac
ttgaacaatcacatcggcgtgccgctgacgcttctttcgcttgacgaagggacggagatg
gccgttgtcgaaatggggatgagcgggtttggcgaaatcgagcggctgaccatgatcgcc
cgtccggacgcagcggtcatcacgaatatcggagaagcacacttgcaggagctcgggtcg
cgggaaggcatcgccaaggcgaagttggaaattttggcgggtttgcaccatgatggttta
ttcgtctaccacggcgatgagccgctcttgacggagcgcgtgccgaagttgctgcttccc
cgccatgtcgtgacgttcggggcgggcgaacagaacgattactatccgaccgatgtgcgc
attgaagcgggaggaacatcgtttgtcatcaatgcgctccccggccggacgctgtttatg
ccggtattaggcaagcatcatgtgtacaacgcgctcgccgccattgcggtcgcccgcttt
ttcggcatcgattgggaaggcattgatgcgtctctctcccgcctgcaagtgacgcgcatg
cgtacggaagtcgtcaaaacaaagtgcggctttacggtcattaacgatgcttacaacgcc
agtccgacatcgatgcgcgccgccttgacgctgcttggggaattaggcggctaccggcaa
aaaatcgccgtattgggcgatatgttggagcttggtgacgaagaagtggcgtttcatcga
gagatcggggaggtgttgcggccgggaatggtggactatgtgttcacttacgggccgctg
gcgcaccatatcgccgcggcggctgccccattttttgatgatgggcgggtgagggagttc
gacgataaagcagcgttggccgaggccgtgcgttccgtcgcgacttcggatgacattgtt
ttattgaaagcatcgcgcggcatgaaattggaagagttgcttcgatattgggtgtaa
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