KEGG   Geobacillus thermocatenulatus: GT3921_04300
Entry
GT3921_04300      CDS       T05178                                 
Name
(GenBank) homoserine dehydrogenase
  KO
K00003  homoserine dehydrogenase [EC:1.1.1.3]
Organism
gtm  Geobacillus thermocatenulatus
Pathway
gtm00260  Glycine, serine and threonine metabolism
gtm00270  Cysteine and methionine metabolism
gtm00300  Lysine biosynthesis
gtm01100  Metabolic pathways
gtm01110  Biosynthesis of secondary metabolites
gtm01120  Microbial metabolism in diverse environments
gtm01230  Biosynthesis of amino acids
Module
gtm_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
gtm_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:gtm00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    GT3921_04300
   00270 Cysteine and methionine metabolism
    GT3921_04300
   00300 Lysine biosynthesis
    GT3921_04300
Enzymes [BR:gtm01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     GT3921_04300
SSDB
Motif
Pfam: Homoserine_dh NAD_binding_3 ACT ACT_AHAS_ss ACT_4 Sacchrp_dh_NADP iHKD DXP_reductoisom
Other DBs
NCBI-ProteinID: ASS98343
UniProt: A0A226Q9E7
LinkDB
Position
857609..858907
AA seq 432 aa
MEKPILVGLLGLGTVGSGVVKIMENHQEKLMHQVGCPVKVKKILVRDVQKPRDVAVDPSL
LTTSAAEVIDDPDIDVIIEVMGGIEETKEWLLRALRQGKHVVTANKDLMAVYGSELLRVA
AEYRCDLFYEASVAGGIPILRSLVDGLASDRITKLMGIVNGTTNYILTKMSQNGASYEDV
LAEAQALGFAEADPTSDVEGLDAARKMAILARLGFSMDIDLDDVQVKGITQVTEEDLNYG
KRLGYTMKLIGIAQRDGQKVEVSVQPTFLPDSHPLASVHNEYNAVYVYGEAVGETMFYGP
GAGSLPTATAVVSDLVAVMKNMRLGVNGHSAVAPQYEKQLKAPAEIFSKYFLRIHVKDQV
GAFAKITTLFSKRGVSFEKILQLPLKEDGLAEIVIVTHDASQQDYEDILQQLGDLEIVER
VQSSYRVEGEKR
NT seq 1299 nt   +upstreamnt  +downstreamnt
atggaaaaacctattttggtcggattgttaggattaggaacggtcgggagcggcgtggtc
aaaattatggaaaaccatcaggaaaagttgatgcatcaagtcgggtgcccggtgaaggtg
aaaaaaatccttgtccgggatgtacagaaaccgcgtgatgtcgccgttgacccgtcgctc
cttacgacgagtgcggctgaggtgatcgacgatccggacattgatgtcatcatcgaagtg
atgggcggcattgaggagacaaaagagtggctattgcgggcgctgcgccaagggaagcat
gtcgtgaccgccaataaagacttaatggccgtctacgggtcggagctgcttcgggtggcg
gcggaataccgctgcgatttattttatgaagcgagcgtcgctggcggcattccgattttg
cgcagcttggtcgacggcttggcgtcggaccggattacgaagctcatgggcattgtgaat
gggacgacgaactacattttgacaaaaatgtcgcaaaacggcgcttcctatgaggacgtg
ctcgccgaagcgcaggcgctcgggtttgcggaagccgatccgacgtcagacgtcgaaggg
ctggatgcggcgcggaaaatggcgattttggcccgccttggcttttcaatggacatcgac
ttggacgatgtgcaagtgaaaggcatcacccaagtgacggaggaagacttgaactacggg
aagcggctcggctacacgatgaaattgatcggcatcgcccagcgcgacgggcagaaggtc
gaggtgagcgtccagccgacgtttttgccggattcgcatccattggcgtccgtgcacaac
gaatacaatgcggtgtacgtatacggcgaagcggtcggagagacgatgttttacgggccg
ggggcgggcagcctgccgacggcgacagccgttgtctccgacttggttgcagtgatgaaa
aacatgcgccttggcgtcaacggccattctgcggttgccccgcaatatgaaaagcaattg
aaagcgccggcggaaattttctcaaaatactttttgcgcattcatgtgaaagaccaagtc
ggcgcgtttgcgaaaattacgacgctgttttccaagcgcggggtgagctttgagaaaatt
ttgcagctgccgctgaaagaggatggcctggcggaaatcgtgatcgtgacgcatgacgcc
tcacagcaagactatgaagacattttgcagcagctgggcgatttggaaatcgtcgaacgg
gtgcaaagctcgtatcgagtggaaggagagaaacggtaa

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