Geobacillus thermodenitrificans: GTNG_0199
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Entry
GTNG_0199 CDS
T00496
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
gtn
Geobacillus thermodenitrificans
Pathway
gtn00300
Lysine biosynthesis
gtn00550
Peptidoglycan biosynthesis
gtn01100
Metabolic pathways
gtn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
gtn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GTNG_0199
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GTNG_0199
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GTNG_0199
Enzymes [BR:
gtn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GTNG_0199
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABO65583
UniProt:
A4IJS9
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All DBs
Position
212831..214213
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AA seq
460 aa
AA seq
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MMKRTVQQIAEMTGGRYANPEWGNIAVSGVSTDTRTIQAGNLYVPLLGETFNGHAFVEEA
AQKGAAAVLWAEAEGTPPESVPAIVVDDTLSALQRLATRYREQLGLKVVGVTGSNGKTTT
KDMIAALLSSQYRVQKTEGNLNNHIGVPLTLLALEEGTDIAVVEMGMSGFGEIEQLTTIA
RPNAAVITNIGEAHLQELGSREGIAKAKLEILSGLQGDGLFVYHGDEPLLAELVPSLPLP
QHVVTFGEGEDNDYYPTTVRIEAAGTSFVINELPRQTLFIPVLGKHHVYNALAAIAVARF
FGVSWENIAAALSRLQVTRMRTEVVKTKRGFTVINDAYNASPTSMRAALMLLTELDGYRK
KIAVLGDMLELGDKEVEFHQAIGEMLRPEMVDYVFTYGPLARHIATAATPFFDQGQVKAF
DDKAALAEAVLSVATPDDIVLLKASRGMRLEELLGYWGEN
NT seq
1383 nt
NT seq
+upstream
nt +downstream
nt
atgatgaaacggacggtgcagcaaattgctgagatgaccggcggccggtacgcgaatccg
gagtgggggaatattgctgtcagcggcgtatcaactgacacgaggacgatccaagctggc
aacttgtacgttccgctgcttggcgagacgtttaacggtcacgctttcgtggaggaagcg
gcgcaaaaaggagcagcagctgtgctgtgggccgaagcggaagggacaccgccagaaagt
gttccggcgattgtcgtcgatgatacgctttcggcactgcagcgtctcgccacccgctac
cgtgaacagctcgggctgaaggttgttggtgtgactggcagcaatggcaaaacgacgacg
aaagatatgatcgctgcgcttctttcatcccaatatcgcgtgcaaaaaacagaaggaaac
ttaaacaaccatatcggcgttccgctcacgctccttgcgctcgaggaggggacagacatc
gccgttgtggaaatggggatgagtgggtttggtgaaattgagcagctcacgacgatcgca
cggccgaatgctgccgtcatcaccaacatcggtgaagcacatttgcaagagctcgggtca
cgggaaggcatcgccaaggcaaagctagaaattttatctggattgcaaggcgacggtttg
ttcgtctatcacggcgatgagccacttttggctgagctcgtgccaagcttgccgcttcct
cagcacgttgtgacgtttggggaaggtgaggacaacgattattatccgacaactgtgcgc
attgaagcagcgggcacgtcgtttgtcatcaacgagctccctcgccagacgctatttatt
ccagttttagggaaacaccatgtatacaacgcgctggccgccatcgctgtcgcccgcttt
ttcggcgtcagctgggagaacattgctgccgctctctcccgcttgcaagtgacgcgcatg
cgtacggaagtcgttaaaacgaagcgcggctttacagtgattaatgatgcctacaacgcc
agcccgacatcgatgcgcgctgctttaatgctgctcacggaattggacggctatcggaag
aaaatcgctgtattgggcgatatgttggagcttggtgacaaagaggtcgagttccaccaa
gcgattggggagatgctgcggccagagatggtagattacgtgtttacttacggaccactg
gcgcgtcatatcgctacggccgccacgccgttttttgatcaaggccaagtgaaggcgttt
gacgataaagcggcattggccgaggcggtgctttccgtcgcaaccccagacgatatcgtt
ttattgaaggcctcgcgtggtatgaggttggaagagttactcggttattggggggaaaat
tag
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