Geotalea uraniireducens: Gura_3978
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Entry
Gura_3978 CDS
T00521
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
gur
Geotalea uraniireducens
Pathway
gur00300
Lysine biosynthesis
gur00550
Peptidoglycan biosynthesis
gur01100
Metabolic pathways
gur01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
gur00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Gura_3978
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Gura_3978
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Gura_3978
Enzymes [BR:
gur01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Gura_3978
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABQ28122
UniProt:
A5G8K4
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Position
complement(4622045..4623451)
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AA seq
468 aa
AA seq
DB search
MFTIDEIIEATGGTRIGSGNDAVSGVSTDSRQVAAGELFVALKGERFDGHDYLEAAVARG
VRAFLVAADRLAGKQPPNDVIYVAVPDTLRALGDLAAWHRSRFDLPLVGITGSNGKTTTK
EMLATILAQTGPGLKTSGNLNNLIGLPLMLLRLTKRDRWAVLEMGMSEPGEIDRLAEMAN
PRIGVITNAFTAHLESMGSVEAVAKAKGELFMRLKTDGWAVYNADDPLISRCPAPAGVKR
LSFGLRGAEVSSEGIESLGREGLRFTLRLPGVDVPVRMKAYGLHNVYNALAAAAAAHLLG
VDPELIRSGLEEFTPYDKRFSLEEIRGVVLVDDSYNANPASMAAALVTLRDIREESRAIA
ILGDMLELGTGSVAAHREVGLLAATCVERLYAMGEMAETVAAGAVDGGLSPENIVVARTH
EEIIADLRRRVAKGDNILVKGSRGMRMDIVAEAIRQGFALPGEKNEVA
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
atgttcacaatcgacgagataatcgaagcaaccggtgggaccaggatcggcagcggcaac
gatgctgtttccggcgtttccaccgattcgcggcaggttgctgccggtgagctcttcgtt
gctttaaagggagaacgattcgacggacatgactatctggaggctgcggttgccagaggt
gtccgcgcttttcttgttgctgcggaccggcttgccggcaagcaaccaccaaacgacgta
atttatgtggcagtacccgataccctaagggcgctcggtgacctggctgcctggcatcgc
agccggttcgacttgccgctggtcgggatcacggggagcaacggcaaaaccaccaccaaa
gagatgctggccacaattctggcgcagaccgggcctggattgaagaccagcggcaatctg
aataacctgatcggcttaccgttgatgctgctgcgcctgacgaaaagggatcgctgggcg
gtccttgagatgggaatgagtgagcctggagaaatagaccgtctggcggaaatggcgaac
ccacggataggggtcattaccaatgcttttaccgctcacctggagagcatggggagtgtg
gaggctgtggcaaaggcgaaaggcgagctgttcatgcgtctcaagacagacggctgggca
gtgtataatgccgacgacccgctcatctcccgatgcccggctcctgccggcgtaaagagg
ctttccttcggcctccgcggggcggaggtgagttcagaagggattgagagcctaggcaga
gaagggctccgcttcacccttcgccttccgggagtggatgtgccggtgcggatgaaggct
tatggcctgcataatgtgtacaatgccctggctgccgccgctgccgcccatctgctcgga
gtggacccggagctgatccgttcggggctggaggagttcaccccctatgacaaacggttc
agtctggaagagatccgcggcgtagtgctcgttgatgacagctataatgcaaatccggcc
tccatggcggcggcgcttgtgactctccgcgatatacgcgaagagagccgtgccattgcg
atccttggagatatgctggaactgggtacaggctctgtggcagcccaccgtgaggtgggg
cttcttgccgcaacctgcgtagagcgcctctacgccatgggcgagatggcggagactgtc
gcggccggagcggttgacggtggtctcagcccggaaaacatcgtcgtggctcgtacccat
gaggagattattgccgacctgcgccgcagggtggccaagggggacaatattctggtcaag
gggtcgcgcggtatgcgcatggatatcgtggcggaagccatcaggcaaggctttgctctg
cctggtgaaaagaacgaggtcgcctga
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