Gardnerella vaginalis 409-05: HMPREF0424_1105
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Entry
HMPREF0424_1105 CDS
T01146
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
gva
Gardnerella vaginalis 409-05
Pathway
gva00300
Lysine biosynthesis
gva00550
Peptidoglycan biosynthesis
gva01100
Metabolic pathways
gva01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
gva00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HMPREF0424_1105 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HMPREF0424_1105 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HMPREF0424_1105 (murF)
Enzymes [BR:
gva01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HMPREF0424_1105 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
CbiA
Motif
Other DBs
NCBI-ProteinID:
ADB13941
LinkDB
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Position
complement(1271237..1272847)
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AA seq
536 aa
AA seq
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MANLEDVMSCVETSCASNAESLDHADMMPMSISEIAKAVHGEIHEFNSCDTDLVANSVFS
DSRQIRNGSVFVAIVGEHVDGHDYVKNAEKSGAVVAIVEHVVEGTNLNQIVVNNSIEALG
LLAKHNLELRRNLNKPFTIIGITGSVGKTTTKDMLKALLSTLGETVAPVGSFNNNIGLPL
TALQVGSNTRFLIAEMGANHVGEIANLTHIAPPDLAIVLKVGVAHLGEFGSVERIAQAKS
EIVRGLLPHGIAVLNSDDKRVSAMSCLVENKHVRWFGRNVKNGLLESASKDDYQLSASNI
KLDSFGKAVFTTTERSNSSNLMNHIEVHLAIQGEHNVMNALAAANVARYLGMTLDDIASV
LSKVSHISPHRMQLSTVSKNDEKFTLIDDSFNANPDSMKAGIDGLCAYENDSCSASSKPF
RIAVLGSMLELGSNEDELHTNIGEYVANSSVDAVVAVGSKTDSDLDKLAHCIAQGARSSW
NNKLLSSHDAVYFVHSADEADDIVWKIVAEHPSSVVLLKGSHASGLSVLAEYWANI
NT seq
1611 nt
NT seq
+upstream
nt +downstream
nt
gtggctaatttggaggatgttatgagttgtgttgaaacttcgtgtgccagcaatgctgag
agtttagatcatgccgatatgatgcctatgagcataagcgaaattgctaaagctgttcat
ggggaaatacacgagtttaatagttgtgacacagatttagttgcaaattccgtttttagt
gattctcgtcaaatccgtaacggttctgtgttcgtagctatagttggtgaacatgttgac
ggtcatgattatgtaaagaatgctgaaaaatctggagctgttgtagctattgttgaacat
gttgtcgaaggcactaatctcaatcaaatagttgtgaataattctatagaagcgctgggc
ttgctagctaaacataatttggaacttcgtcgcaatcttaacaaacctttcactattatt
ggtattactggttccgttggtaaaacaacaacgaaagatatgttgaaggctttgttgagc
acgctaggcgaaacagttgctcctgttggatcttttaataataatattggtttgcctctt
actgctttgcaagttggcagtaatactcgatttttaatagcagaaatgggagctaatcat
gttggcgaaattgccaatttaactcatattgctcctccggatctcgcaatagtgcttaaa
gttggtgtggctcatttaggtgaatttggctcagttgagcgcattgcgcaagcaaaaagt
gagattgtgcgtgggcttttgccacatggcatagcagtattaaattccgacgataagcga
gtttctgcaatgtcttgtcttgtagaaaataagcatgtgcgctggttcggtagaaatgtt
aaaaacggattgctggaatcagctagtaaagatgactaccaactttcagctagtaatata
aagttagattcttttggtaaggcagtttttactaccactgaacgtagtaattcttctaat
ctaatgaatcatattgaagtgcatcttgctatacaaggcgagcataatgttatgaatgcg
cttgcagcagcaaatgttgctagatatttgggaatgactttagatgatattgcttctgtg
ctgtctaaagtttcgcatattagcccgcatcgcatgcaattgagtacagtttctaagaat
gacgagaaatttacacttattgatgattcctttaatgcaaatcctgattctatgaaagca
ggaatcgatggtttgtgcgcttatgaaaatgattcttgtagtgcatcttcgaaacctttc
cgtatagcggttcttggttctatgttggagcttggcagcaacgaagatgaattgcacaca
aatattggagaatatgtggcaaattcgagtgtcgatgcagttgttgctgttggttcaaaa
acggactctgacttagataaattagctcactgtattgctcaaggtgcacgttcttcttgg
aataataaactactttcttctcacgatgcagtctactttgtgcacagtgcggatgaggct
gatgatattgtttggaaaattgtggccgagcatccgagtagtgttgtgttattgaaaggc
tctcatgcttcaggcttgagtgtgcttgctgaatattgggcaaatatttaa
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