KEGG   Galeopterus variegatus (Sunda flying lemur): 103585135
Entry
103585135         CDS       T08727                                 
Symbol
PRKACA
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit alpha isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
gvr  Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr01522  Endocrine resistance
gvr04010  MAPK signaling pathway
gvr04014  Ras signaling pathway
gvr04020  Calcium signaling pathway
gvr04024  cAMP signaling pathway
gvr04062  Chemokine signaling pathway
gvr04081  Hormone signaling
gvr04082  Neuroactive ligand signaling
gvr04114  Oocyte meiosis
gvr04140  Autophagy - animal
gvr04211  Longevity regulating pathway
gvr04213  Longevity regulating pathway - multiple species
gvr04261  Adrenergic signaling in cardiomyocytes
gvr04270  Vascular smooth muscle contraction
gvr04310  Wnt signaling pathway
gvr04340  Hedgehog signaling pathway
gvr04371  Apelin signaling pathway
gvr04530  Tight junction
gvr04540  Gap junction
gvr04611  Platelet activation
gvr04713  Circadian entrainment
gvr04714  Thermogenesis
gvr04720  Long-term potentiation
gvr04723  Retrograde endocannabinoid signaling
gvr04724  Glutamatergic synapse
gvr04725  Cholinergic synapse
gvr04726  Serotonergic synapse
gvr04727  GABAergic synapse
gvr04728  Dopaminergic synapse
gvr04740  Olfactory transduction
gvr04742  Taste transduction
gvr04750  Inflammatory mediator regulation of TRP channels
gvr04910  Insulin signaling pathway
gvr04911  Insulin secretion
gvr04912  GnRH signaling pathway
gvr04913  Ovarian steroidogenesis
gvr04914  Progesterone-mediated oocyte maturation
gvr04915  Estrogen signaling pathway
gvr04916  Melanogenesis
gvr04918  Thyroid hormone synthesis
gvr04919  Thyroid hormone signaling pathway
gvr04921  Oxytocin signaling pathway
gvr04922  Glucagon signaling pathway
gvr04923  Regulation of lipolysis in adipocytes
gvr04924  Renin secretion
gvr04925  Aldosterone synthesis and secretion
gvr04926  Relaxin signaling pathway
gvr04927  Cortisol synthesis and secretion
gvr04928  Parathyroid hormone synthesis, secretion and action
gvr04934  Cushing syndrome
gvr04935  Growth hormone synthesis, secretion and action
gvr04961  Endocrine and other factor-regulated calcium reabsorption
gvr04962  Vasopressin-regulated water reabsorption
gvr04970  Salivary secretion
gvr04971  Gastric acid secretion
gvr04976  Bile secretion
gvr05012  Parkinson disease
gvr05020  Prion disease
gvr05030  Cocaine addiction
gvr05031  Amphetamine addiction
gvr05032  Morphine addiction
gvr05034  Alcoholism
gvr05146  Amoebiasis
gvr05163  Human cytomegalovirus infection
gvr05165  Human papillomavirus infection
gvr05166  Human T-cell leukemia virus 1 infection
gvr05200  Pathways in cancer
gvr05203  Viral carcinogenesis
gvr05205  Proteoglycans in cancer
gvr05207  Chemical carcinogenesis - receptor activation
gvr05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:gvr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103585135 (PRKACA)
   04014 Ras signaling pathway
    103585135 (PRKACA)
   04310 Wnt signaling pathway
    103585135 (PRKACA)
   04340 Hedgehog signaling pathway
    103585135 (PRKACA)
   04371 Apelin signaling pathway
    103585135 (PRKACA)
   04020 Calcium signaling pathway
    103585135 (PRKACA)
   04024 cAMP signaling pathway
    103585135 (PRKACA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    103585135 (PRKACA)
   04081 Hormone signaling
    103585135 (PRKACA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103585135 (PRKACA)
  09143 Cell growth and death
   04114 Oocyte meiosis
    103585135 (PRKACA)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    103585135 (PRKACA)
   04540 Gap junction
    103585135 (PRKACA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103585135 (PRKACA)
   04062 Chemokine signaling pathway
    103585135 (PRKACA)
  09152 Endocrine system
   04911 Insulin secretion
    103585135 (PRKACA)
   04910 Insulin signaling pathway
    103585135 (PRKACA)
   04922 Glucagon signaling pathway
    103585135 (PRKACA)
   04923 Regulation of lipolysis in adipocytes
    103585135 (PRKACA)
   04912 GnRH signaling pathway
    103585135 (PRKACA)
   04913 Ovarian steroidogenesis
    103585135 (PRKACA)
   04915 Estrogen signaling pathway
    103585135 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    103585135 (PRKACA)
   04921 Oxytocin signaling pathway
    103585135 (PRKACA)
   04926 Relaxin signaling pathway
    103585135 (PRKACA)
   04935 Growth hormone synthesis, secretion and action
    103585135 (PRKACA)
   04918 Thyroid hormone synthesis
    103585135 (PRKACA)
   04919 Thyroid hormone signaling pathway
    103585135 (PRKACA)
   04928 Parathyroid hormone synthesis, secretion and action
    103585135 (PRKACA)
   04916 Melanogenesis
    103585135 (PRKACA)
   04924 Renin secretion
    103585135 (PRKACA)
   04925 Aldosterone synthesis and secretion
    103585135 (PRKACA)
   04927 Cortisol synthesis and secretion
    103585135 (PRKACA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103585135 (PRKACA)
   04270 Vascular smooth muscle contraction
    103585135 (PRKACA)
  09154 Digestive system
   04970 Salivary secretion
    103585135 (PRKACA)
   04971 Gastric acid secretion
    103585135 (PRKACA)
   04976 Bile secretion
    103585135 (PRKACA)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    103585135 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    103585135 (PRKACA)
  09156 Nervous system
   04724 Glutamatergic synapse
    103585135 (PRKACA)
   04727 GABAergic synapse
    103585135 (PRKACA)
   04725 Cholinergic synapse
    103585135 (PRKACA)
   04728 Dopaminergic synapse
    103585135 (PRKACA)
   04726 Serotonergic synapse
    103585135 (PRKACA)
   04720 Long-term potentiation
    103585135 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    103585135 (PRKACA)
  09157 Sensory system
   04740 Olfactory transduction
    103585135 (PRKACA)
   04742 Taste transduction
    103585135 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    103585135 (PRKACA)
  09149 Aging
   04211 Longevity regulating pathway
    103585135 (PRKACA)
   04213 Longevity regulating pathway - multiple species
    103585135 (PRKACA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    103585135 (PRKACA)
   04714 Thermogenesis
    103585135 (PRKACA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103585135 (PRKACA)
   05205 Proteoglycans in cancer
    103585135 (PRKACA)
   05207 Chemical carcinogenesis - receptor activation
    103585135 (PRKACA)
   05203 Viral carcinogenesis
    103585135 (PRKACA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103585135 (PRKACA)
   05163 Human cytomegalovirus infection
    103585135 (PRKACA)
   05165 Human papillomavirus infection
    103585135 (PRKACA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    103585135 (PRKACA)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    103585135 (PRKACA)
   05020 Prion disease
    103585135 (PRKACA)
  09165 Substance dependence
   05030 Cocaine addiction
    103585135 (PRKACA)
   05031 Amphetamine addiction
    103585135 (PRKACA)
   05032 Morphine addiction
    103585135 (PRKACA)
   05034 Alcoholism
    103585135 (PRKACA)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    103585135 (PRKACA)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    103585135 (PRKACA)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103585135 (PRKACA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:gvr01001]
    103585135 (PRKACA)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:gvr03019]
    103585135 (PRKACA)
   03036 Chromosome and associated proteins [BR:gvr03036]
    103585135 (PRKACA)
Enzymes [BR:gvr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     103585135 (PRKACA)
Protein kinases [BR:gvr01001]
 Serine/threonine kinases: AGC group
  PKA family
   103585135 (PRKACA)
Messenger RNA biogenesis [BR:gvr03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     103585135 (PRKACA)
Chromosome and associated proteins [BR:gvr03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    103585135 (PRKACA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 103585135
NCBI-ProteinID: XP_008564241
LinkDB
Position
Unknown
AA seq 351 aa
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML
VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgggcaacgccgccgccgccaagaagggcagcgagcaggagagcgtgaaagagttctta
gccaaagccaaagaagattttcttaaaaaatgggaaagtcctgctcagaatacagcccat
ttggatcagtttgaacgaatcaagactctcggcacaggctcctttgggcgggtgatgctg
gtgaagcacaaggagaccgggaaccactatgccatgaaaatcctcgacaaacagaaggtg
gtgaagctgaaacagatcgagcacaccctgaatgaaaagcgcatcctgcaagcagtcaac
ttcccgttcctcgtcaaacttgagttctccttcaaggacaactcaaacttatacatggtc
atggagtatgtgcctggcggggagatgttctcgcacctacggcggatcggaaggttcagt
gagccccatgcccgtttctacgcggcccagatcgtcctgacgttcgagtacctgcactcg
cttgatctgatctaccgggacctgaagccggagaacctcctcattgaccagcagggctac
attcaggtgacagacttcggttttgccaagcgtgtgaagggccgcacctggaccttgtgt
gggacccctgagtacctggcccccgagattatcctgagcaaaggctacaacaaggctgtg
gactggtgggccctgggtgttctcatctatgagatggctgctggctacccacccttcttt
gctgaccagcccatccagatctacgagaagatcgtctctgggaaggtgcggttcccgtcc
cacttcagctctgacttgaaggacctgctgcggaaccttctacaggtggatctcaccaag
cgcttcgggaacctcaagaatggggtcaacgatatcaagaaccacaagtggtttgccaca
actgactggattgccatctaccagaggaaggtggaagctcccttcataccaaagtttaaa
ggccctggggacacaagtaactttgacgactatgaggaggaagagatccgggtctccatc
aatgagaagtgtggcaaggagttttctgagttttag

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