Galeopterus variegatus (Sunda flying lemur): 103586004
Help
Entry
103586004 CDS
T08727
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr00230
Purine metabolism
gvr00670
One carbon pool by folate
gvr01100
Metabolic pathways
gvr01523
Antifolate resistance
Module
gvr_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103586004 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
103586004 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103586004 (GART)
Enzymes [BR:
gvr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
103586004 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
103586004 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
103586004 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
AIRS_C
GARS_C
AIRS
Sacchrp_dh_NADP
DUF3104
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
103586004
NCBI-ProteinID:
XP_008565349
LinkDB
All DBs
Position
Unknown
AA seq
978 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISITDHTALAQ
FCKDEKIEFVVIGPEAPLAAGIVGNLTSAGVQCFGPTAEAAQLESSKKFAKEFMDRHGIP
TAQWRAFTKPEEACSFIMRNLLSQEKAFGAAGETIVIEELLEGEEVSCLCFTDGRTVAPM
PPAQDHKRLLEGDCGPNTGGMGACCPAPQVSKDLLLKIKNTILQRTVDGMQQEGTPYTGI
LYAGIMLTKDGPKVLEFNCRFGDPECQVILPLLKSDLYEVIQSTLGGLLCTSLPIWLENH
TAITIVMASKGYPGDYTKGVEITGFPEAQALGLEVFHAGTALKDGKVVTNGGRVLTVTAI
REDFLSALDEAKKGLATIKFEGAVYRKDIGFRAIAFLQQPRGLTYKESGVDIAAGNMLVK
KIQPLAKATSRPGCEVDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQLCNKHDTI
GQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSTTEAVVAGIAKACGKAGCALLGGETA
EMPDMYPPGEYDLAGFAVGAMERDQKLPHLERITEGDIVIGIASSGLHSNGFSLVRKIVA
KSSLRYSSPAPDGCGDQTLGDLLLTPTRIYSHSLLPILRSGHVKAFAHITGGGLLENIPR
VLPQKFGVDLDARSWRIPRVFSWLQQEGHLSEEEMARTFNCGVGAALVVSKDQTEQILRD
IQQHKEEAWVIGSVVACPEGSPRVKVKNLIETIRINGSVLENGSLKNYFSVKPKKARVAV
LISGTGSNLQALIDSTQDPNSSAHIVVVISNKAAVAGLDKAERAGIPTKVINHKLYKNRV
EFDNAIDQVLEEFSTDIVCLAGFMRILSGPFVRKWNGKMLNVHPSLLPSFKGSNAHAQVL
ETGVTITGCTVHFVTEDVDAGQIILQEAVPVKRGDTVTTLSERVKLAEHKIFPAALQLVS
SGTVQLGENGKICWVKEE
NT seq
2937 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtaattggcagtggaggaagggaacatacactggcctggaaa
cttgcacagtctcatcatgtcaaacaagtattggtggccccaggaaatgcaggcactgcc
tgctctgaaaagatttcaaatactgcaatctcaatcactgatcacactgcccttgctcaa
ttctgcaaagatgagaaaattgaatttgtagtcattggaccagaggcacctctggctgcc
ggaattgttgggaatctgacctctgcaggagtgcaatgctttggccccacagcagaagca
gctcagttagagtccagcaaaaagtttgccaaagagtttatggaccgacatggaatccca
actgcacaatggagagctttcaccaaacctgaagaggcctgcagcttcattatgagaaat
ctactttcccaggagaaagcttttggagcagctggagaaacaattgtcattgaagaactt
cttgaaggagaagaggtgtcttgtctgtgtttcactgatgggaggactgtggcccccatg
cccccagcacaggaccataagcgattactggagggagactgtggccccaacacaggggga
atgggagcctgttgtccagcacctcaggtttctaaggatttgttactaaaaattaaaaat
actattcttcaaaggacagtagatggcatgcagcaggagggtactccatacacaggtatt
ctctatgctggcataatgctgaccaaggatggtccaaaagttctggagtttaactgccgt
tttggtgatccagagtgccaagtaatccttccacttcttaaaagtgatctttatgaagtg
attcagtccactttaggtggcctgctctgcacatctctgcccatttggctagaaaaccac
actgccataactattgtcatggcaagtaaaggttaccctggagactacaccaagggagtg
gagataacagggtttcctgaggctcaagctttaggactggaggtgttccatgcaggtact
gccctcaaagatggcaaagtagtgaccaacgggggtagagtccttaccgtaacagccatc
cgggaagatttcctgtcagcccttgacgaagccaagaaaggactagctactataaagttt
gagggagcagtttatagaaaggatattggctttcgtgccatagctttcctccagcagccc
aggggcctgacttacaaggaatctggggtagacattgcagctggaaatatgctagtcaag
aagattcagcctttagcaaaagccacctccagaccaggctgtgaagttgaccttggaggt
tttgctggtctttttgatttgaaagcagctggtttcaaagatcctctcctggcctctgga
acagatggcgttggaactaaactgaagattgcgcagctatgcaataaacatgataccatt
ggtcaagatttggttgcaatgtgtgtaaatgatattctggcacaaggagcagagccactc
ttcttcctcgattacttttcctgcggaaaacttgaccttagtacaactgaagctgttgtt
gctggaatcgctaaagcttgtggaaaggctggatgtgctctccttggaggtgaaacagca
gaaatgcctgacatgtatcctcctggagagtacgacctcgctggttttgctgtcggtgcc
atggaacgggatcagaaactccctcacctggaaagaatcactgaaggggatattgttatt
ggaatagcttcatctggtcttcacagcaatggatttagccttgtgaggaaaattgtagca
aaatcttccctccgttactcctctccagcacctgatggttgtggtgaccagactttaggg
gatttacttctgactccaaccagaatctacagccattcactgttacctatcctacgttca
ggacatgtcaaagcatttgcccatattactggtggaggattgctagaaaacatccccaga
gtcctccctcaaaaatttggagtggatttagatgcccggtcctggaggatccccagagtc
ttctcatggttacaacaggaaggacacctctctgaagaagagatggccagaacatttaac
tgtggggttggggctgccctcgtggtatcaaaggatcagacagagcagattctgagggat
attcagcagcacaaggaagaagcctgggtgataggcagtgtggtggcatgtcctgaaggt
tcccctcgtgtgaaagtcaagaatctgattgaaaccatacgaataaatgggtcagtctta
gagaatggctccctgaaaaactatttctctgtcaaaccaaaaaaggcaagagtggctgtc
ttaatatctggaacaggatcgaacctccaagcacttatagacagtactcaggatccaaat
agctctgcacatattgttgttgttatctccaacaaagctgcagtggctgggttagataaa
gcagaaagagctggtattcccaccaaagtaattaatcataaattatataaaaatcgtgta
gaatttgataatgcaattgaccaagtccttgaagaattctccacagacatagtctgtctt
gcaggattcatgagaattctatctggcccctttgtcagaaagtggaatggaaaaatgctc
aacgtccacccctccttgctcccttcttttaagggttcaaatgcccatgcgcaagtcttg
gaaactggagtcacaattactgggtgcactgtacactttgtaactgaagacgtagatgct
ggacaaattattttacaagaagctgttcccgtgaagaggggtgacactgttacgactctg
tctgagagagtgaaattagcagaacataaaatatttcctgcagccctccagctggtgtcc
agtggaactgtacagcttggagaaaatggcaagatctgttgggtcaaagaggagtga
DBGET
integrated database retrieval system
