Galeopterus variegatus (Sunda flying lemur): 103588305
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Entry
103588305 CDS
T08727
Symbol
HSPA5
Name
(RefSeq) 78 kDa glucose-regulated protein
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr03060
Protein export
gvr04141
Protein processing in endoplasmic reticulum
gvr04612
Antigen processing and presentation
gvr04918
Thyroid hormone synthesis
gvr05012
Parkinson disease
gvr05014
Amyotrophic lateral sclerosis
gvr05020
Prion disease
gvr05022
Pathways of neurodegeneration - multiple diseases
gvr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
103588305 (HSPA5)
04141 Protein processing in endoplasmic reticulum
103588305 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
103588305 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
103588305 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
103588305 (HSPA5)
05014 Amyotrophic lateral sclerosis
103588305 (HSPA5)
05020 Prion disease
103588305 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
103588305 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103588305 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
gvr03110
]
103588305 (HSPA5)
04131 Membrane trafficking [BR:
gvr04131
]
103588305 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
gvr04147
]
103588305 (HSPA5)
Enzymes [BR:
gvr01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
103588305 (HSPA5)
Chaperones and folding catalysts [BR:
gvr03110
]
Heat shock proteins
HSP70 / DNAK
103588305 (HSPA5)
Membrane trafficking [BR:
gvr04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
103588305 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
103588305 (HSPA5)
Exosome [BR:
gvr04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
103588305 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
103588305 (HSPA5)
Exosomal proteins of colorectal cancer cells
103588305 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
103588305
NCBI-ProteinID:
XP_008568189
LinkDB
All DBs
Position
Unknown
AA seq
654 aa
AA seq
DB search
MKLSLVAAVLLLLGAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEDDTAEKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagctctccctggtggccgcggtgttgctgctgctcggcgcggcgcgtgccgaggag
gaggacaagaaggaggacgtgggcacggtggtcggcatcgacttggggaccacctactcc
tgcgtcggggtgttcaagaacggccgcgtggagatcatcgccaacgaccagggcaaccgc
atcacgccgtcttatgtggccttcacccctgaaggggagcgtctgataggcgacgcggcc
aagaaccagctcacctccaaccccgagaacacagtcttcgacgccaagcggctcatcggc
cgcacctggaacgacccatctgtgcagcaggacatcaagttcctgcctttcaaggtggtt
gaaaagaaaactaaaccatacattcaggttgatattggaggtgggcaaacaaagacattt
gcccctgaagaaatttctgccatggttctcactaaaatgaaagaaactgctgaggcttat
ttgggaaagaaggttacccatgcagttgttactgtaccagcctatttcaatgatgcccag
cgacaagcaaccaaagatgctggaactattgctggactgaatgtcatgaggatcatcaat
gagcctacagcagctgctattgcttatggcctggataagagggagggggagaagaacatc
ctggtgttcgacttgggtggtggaacctttgatgtatctcttctcaccattgacaatggc
gtcttcgaagtcgtggccactaatggagatacccatctgggtggagaagactttgaccag
cgtgttatggaacacttcatcaagctgtacaaaaagaagactggcaaagatgttaggaaa
gacaacagagctgtgcagaaactccggcgtgaggtagaaaaggccaaacgggccctgtct
tctcaacaccaagcaagaattgaaattgagtccttctatgaaggagaagacttttctgag
actctgactcgggccaaatttgaagagctaaacatggatctgttccggtctaccatgaag
cctgtccagaaagtgttggaggattcagatttgaagaagtctgatattgatgaaattgtt
cttgtcggtggctctactcgaattccaaagattcaacaactggttaaagagttcttcaat
ggcaaggagccatcccgtggcattaacccagatgaggctgtagcatatggtgctgctgtc
caggctggtgtactctctggtgatcaagatacaggtgatctggtactgcttgatgtatgc
ccccttacacttggtattgaaactgtgggaggtgtcatgaccaaactgattccaaggaac
actgtggtgcccaccaagaagtctcaaatcttttctacagcctctgataatcaaccaact
gttacaatcaaggtctatgaaggtgaacgacccctgacgaaagacaatcaccttctgggt
acatttgatctgactggaatccctcctgctccccgtggggtcccacagattgaagtcacc
ttcgagatagatgtgaatggcattcttcgagtgacagctgaagacaagggtacagggaac
aaaaataagatcacaattaccaatgaccaaaaccgcctgacacctgaagaaattgaaagg
atggttaatgatgctgagaagtttgctgaggaagacaaaaagctcaaggagcgcattgac
actagaaatgagttagaaagctatgcctactctctgaagaaccagattggagataaagaa
aagctaggaggtaaactttcctctgaagataaggaaaccatggaaaaagctgtagaggaa
aagattgaatggctggaaagccaccaagatgctgacattgaagacttcaaagctaaaaag
aaggaactagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggccct
cctccaactggtgaagatgatacagcagaaaaagatgagttgtag
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