Galeopterus variegatus (Sunda flying lemur): 103594750
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Entry
103594750 CDS
T08727
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr04217
Necroptosis
gvr04380
Osteoclast differentiation
gvr04620
Toll-like receptor signaling pathway
gvr04621
NOD-like receptor signaling pathway
gvr04630
JAK-STAT signaling pathway
gvr04658
Th1 and Th2 cell differentiation
gvr04659
Th17 cell differentiation
gvr05145
Toxoplasmosis
gvr05160
Hepatitis C
gvr05161
Hepatitis B
gvr05162
Measles
gvr05164
Influenza A
gvr05165
Human papillomavirus infection
gvr05167
Kaposi sarcoma-associated herpesvirus infection
gvr05168
Herpes simplex virus 1 infection
gvr05169
Epstein-Barr virus infection
gvr05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
103594750 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
103594750 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
103594750 (TYK2)
04621 NOD-like receptor signaling pathway
103594750 (TYK2)
04658 Th1 and Th2 cell differentiation
103594750 (TYK2)
04659 Th17 cell differentiation
103594750 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
103594750 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
103594750 (TYK2)
05160 Hepatitis C
103594750 (TYK2)
05171 Coronavirus disease - COVID-19
103594750 (TYK2)
05164 Influenza A
103594750 (TYK2)
05162 Measles
103594750 (TYK2)
05168 Herpes simplex virus 1 infection
103594750 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
103594750 (TYK2)
05169 Epstein-Barr virus infection
103594750 (TYK2)
05165 Human papillomavirus infection
103594750 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
103594750 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gvr01001
]
103594750 (TYK2)
Enzymes [BR:
gvr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103594750 (TYK2)
Protein kinases [BR:
gvr01001
]
Non-receptor tyrosine kinases
JAK family [OT]
103594750 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
103594750
NCBI-ProteinID:
XP_008576232
UniProt:
A0ABM0R6J1
LinkDB
All DBs
Position
Unknown
AA seq
1177 aa
AA seq
DB search
MPLCQGRATRGRKPDEDGAQPMAALGGLKVLLHWAGPDGGEPWVTFSEASLTAEDVCIQI
AHKIGITPPCVNLFALFDAQAQVWLPPNHILEVSGDPSLMLYFRMRFYFRNWHGMNPQEP
AVYRCGPPGSEASSEQAEHGVQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHFK
NESLGMAFLHLCQLALRHNVPLEQVAKETSFKDCIPRSFRQQIQQHNALTRLRLQNVFRR
FLRAFQPGCLSQQVVMVKYLATLERLAPRFCAERVPVCHLELRAQAEGEPCYIRDSGQAP
PAPSPEAAVGPSTHEVLVTGTGGIQWRAVKAEGSSAGSGTSRSPQATLSGKKAKAHEASD
QPADRPQEPPWAYFCDFQDITHMVLKECHVSVHRQDNKCLELSLPSRATALSFVALVDGY
FRLTADSSHYLCHEVAPPRLVMSIQEGIHGPLLEPFVRAKLQLEEGLFLIHWSTSHLYRL
ILTVAQRDQAPSACSWRLRKFPITQQAGAFVLEGWGRAFASVHELRAALQGCSLRAGDDC
FSLRRCCLPRPGEISNLIVMRGPRASTRPLNLNQLSFHRIRQEEITQLSHLGQGTRTNVY
KGLLRVGGPQEGKVDGEEADRSLGQDLRVVLKVLDSSHHNIALAFYETASLMSQVSHVHL
AFVHGVCVRGSDNIMVTEYVEHGPLDVWLRRQRGHLPMAWKVTVAQQLASALSYLEDKNL
VHGNVCGRNILLARLGQAEGTSPFIKLSDPGVGLGALSREERVERIPWIAPECLPSGANS
LSTAADKWGFGATLLEICFNGEVPLQGHSPSQKERFYQKQHQLPEPSCPELATLTSQCLT
YDPIQRPSFRTILRDLTQLQPHKLVDVLAVNPNSPASDSKVFHKRYLKKIRDLGEGHFGK
VSLYCYDPTNDGTGEMVAVKALKAGSGPQLCYGWRREIDILRTLDHEHIVKYKGCCEDQG
EKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL
LDNDRLVKIGDFGLAKAVPEGHEYYCVREDGDSPVFWYAPECLKECKFYYASDVWSFGVT
LYELLTHCDSSQSPPSKFIELIGPTQGQMTIPRLIELLDQGERLPQPDKCPYEVYLLMKN
CWETEASFRPTFQNLIPIFKTVHEKYQGQAPSVFSVC
NT seq
3534 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccaggggcgggccaccaggggcagaaagcctgatgaggatggagctcag
cccatggctgccctgggagggctgaaggtgcttctgcactgggctggccctgatggcgga
gagccctgggtcaccttcagtgaggcctcgctgacggccgaagacgtctgcatacagatt
gcacacaaaattggtatcactccaccctgtgtcaatctctttgccctctttgatgcccag
gcccaagtgtggctgcccccaaaccacatcttagaggtgtctggagacccaagcctgatg
ctgtatttccgcatgaggttttatttccggaactggcatggcatgaatcctcaggagccg
gctgtgtaccgctgtggacccccagggtctgaggcttcctcagaacaggcagagcatggg
gtgcaactcctggacccagcttcctttgagtacctctttgagcagggcaagcatgagttt
gtgaacgatgtggcatcattgtgggagctatcaagtgaagaggagatccaccactttaag
aatgagagcctgggcatggcctttctgcacctctgccaacttgctctccgccacaatgtc
cccctggagcaggtggccaaggagaccagcttcaaggactgcatcccgcgctccttccga
cagcagatccagcagcataacgcgctgacgcggctgcgcctgcagaatgtcttccgcagg
ttcctgcgggccttccagccgggctgcctctcccagcaggtcgtcatggtcaagtacctg
gccacactggagcggctggcaccccgcttctgcgcagagcgtgtgcctgtgtgccacctg
gagctgcgggcccaggccgagggggagccctgctacatccgggacagtgggcaggcccct
ccagcccccagccccgaggctgctgtgggcccctccacccacgaggtgctagtgacaggc
actggtggcattcagtggcgggcagtgaaggcagagggttccagtgctggcagcggcacc
agcaggagtcctcaagccaccctatctgggaagaaagccaaggcacatgaggcaagcgac
cagccagcggacaggccacaggagccgccatgggcctacttctgtgacttccaggacatc
acccacatggtgctgaaagagtgccacgtcagcgtccaccggcaggacaacaagtgcctg
gagctgagcctgccctcccgggctacagccctgtccttcgtggcgctggtggatggctat
ttccgcctgacggctgactccagccactacctgtgccacgaggtggcccccccgcggctg
gtgatgagcatccaggagggtatccacgggcccctgctggagccatttgtgcgggccaag
ctgcagctggaggagggtctctttctcatccactggagcaccagccacctctaccgcctc
atcctcacggtggcccagcgtgatcaggcccccagcgcatgcagctggcgcctgcgcaag
ttccccatcacgcagcaggcgggggccttcgtgctggagggctggggccgggcctttgcc
agcgtgcacgagctgcgggccgccttgcagggctgctccctgcgggccggggacgactgc
ttctccctgcgccgctgctgcctgccacggccaggagagatctccaacctcattgtcatg
cgggggcctcgggccagcaccaggccactgaacctcaaccagctcagcttccaccgcatc
cgccaggaggagatcacccagctgtcccacctgggccaaggcacacggaccaatgtgtac
aagggcctcctgcgagtgggaggcccccaggaaggcaaagtggatggtgaggaagctgac
agaagccttggccaggacctgagagtggtgctcaaagtgctggactccagtcaccacaac
atcgccctggccttctatgagacagccagcctcatgagccaggtctcccacgtgcacctg
gcctttgtgcatggcgtctgcgtgcgcggctctgacaacatcatggtgacggagtatgtg
gaacatgggcccctggacgtgtggctgcggcgacagcggggccatttgcctatggcctgg
aaggtgacagtggcccagcagctggccagtgccctcagctacctggaggacaagaacttg
gttcatggtaacgtgtgtggccggaacatcctgctggcgcggctggggcaggctgagggc
actagccccttcatcaagctgagtgacccgggcgtgggcctgggtgccctctccagggag
gagcgagtggagcggatcccctggatagcccctgagtgcctgcccagcggggccaacagc
ctgagcacggccgctgacaagtggggctttggtgccaccctcctggagatctgctttaat
ggggaggtccccctgcagggccacagcccctcccagaaagagcgtttctaccagaagcag
caccagctgcccgagccctcatgtccagagctggccacgctcaccagccagtgcttgacc
tatgaccccatccagcggccatcattccgcactattcttcgcgacctcactcagctgcag
ccccacaaactcgttgatgtcttggccgtgaacccgaactcaccggcgtcagactccaag
gttttccacaagcgctatttgaaaaagatccgggatctgggcgagggtcacttcggcaaa
gtcagtttgtactgctacgacccgaccaatgacggcactggcgagatggtggccgtgaaa
gccctcaaggcgggcagcggcccccagctctgctacggctggaggcgggagatcgatatc
ctgcgcacgctcgaccacgagcacatcgtcaagtacaagggctgctgcgaggaccaaggc
gagaaatcggtgcagctggtcatggagtacgtgcccctgggcagcctccgagactacctt
ccccggcacagcgtcggactggcccagctgctacttttcgcccagcagatctgcgagggc
atggcctatctacacgctcagcactacatccaccgagacctagctgcgcgcaacgtgctg
ctggacaacgacaggctggtcaagatcggggactttggcctagccaaggctgtgcccgaa
ggccacgagtactactgcgtgcgcgaggatggggacagccccgtattctggtatgcccca
gaatgcctgaaggagtgtaagttctactacgcatctgacgtctggtctttcggggtcacc
ctgtatgaattgctgacgcactgtgactccagccagagccccccatcgaaattcatcgag
ctcataggccccacccaggggcagatgaccataccgagactcattgagctgctggatcaa
ggggagaggctgccacagcctgacaaatgtccctatgaggtctatcttctcatgaagaac
tgctgggaaacagaggcctcgttccgcccgaccttccagaacctcatacccatcttcaag
acagtccacgagaaataccaaggccaggctccttcggtgtttagcgtgtgctga
DBGET
integrated database retrieval system
