Galeopterus variegatus (Sunda flying lemur): 103595434
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Entry
103595434 CDS
T08727
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein PURH
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr00230
Purine metabolism
gvr00670
One carbon pool by folate
gvr01100
Metabolic pathways
gvr01523
Antifolate resistance
Module
gvr_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103595434 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
103595434 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103595434 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
gvr04147
]
103595434 (ATIC)
Enzymes [BR:
gvr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
103595434 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
103595434 (ATIC)
Exosome [BR:
gvr04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
103595434 (ATIC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
103595434
NCBI-ProteinID:
XP_008577054
UniProt:
A0ABM0R8W3
LinkDB
All DBs
Position
Unknown
AA seq
533 aa
AA seq
DB search
MLGGRVKTLHPAVHAGILARNIPEDNADMARLNFNLIRVVACNLYPFVKTVASPDVTVEE
AVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSDSKDTSLETRRQLALKAF
THTAQYDEAISDYFRKQYGKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFIN
LCDALNAWQLVTELKEALGIPAAASFKHVSPAGAAAGIPLSEDEAKVCMVYDLFKTLTPV
STAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALKILSKKKN
GNYCVLQMDQSYKPDENEVRTLFGLRLSQKRNNGVIDRSLFSNVVTKNKDLPESALRDLI
VATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFK
TGVKRAEISNAIDQYVTGTIGEGEDLIKWKALFEEVPELLTEAEKKEWIDRLSEVSVSSD
AFFPFRDNVDRAKRSGVAYIAAPSGSAADEVVIEACDELGIILAHTNLRLFHH
NT seq
1602 nt
NT seq
+upstream
nt +downstream
nt
atgttagggggacgtgtgaaaacgttgcatcctgcagttcatgctggaatcctggctcgt
aatatcccagaagataatgctgacatggccagacttaatttcaatcttataagagttgtt
gcctgtaatctgtatccctttgtgaagacagtggcttctccagatgtgactgttgaggag
gctgttgagcaaattgatatcggtggagtgactttattgagagccgcagccaaaaaccac
gctcgggtgacggtagtgtgtgaaccagaggactatgtggtggtgtccacagagatgcag
agctccgatagtaaggacacctccttggagaccagacgacagttagccttgaaggcattc
actcatacagcacagtatgatgaagcaatttcagattactttaggaaacagtacggtaaa
ggaatatctcagatgcccttgaggtatggaatgaatcctcatcaaactcctgcccagctg
tacacactgaagcccaagcttcccatcacagttctaaatggagcccctggatttataaac
ttgtgtgatgctttgaatgcctggcagctggtgacagagctcaaagaagctttaggcatt
ccagccgctgcctctttcaaacatgtcagccctgcaggtgctgctgctggaattccactc
agtgaggatgaggccaaagtctgcatggtctatgatctctttaaaacccttacacccgta
tcaactgcatatgcaagagcaagaggggctgataggatgtcttcatttggtgattttgtt
gcattatctgatgtttgtgatgtaccaactgcgaaaattatctccagagaagtgtctgat
ggtattattgcccctggttatgaagaagaagccttgaaaatactttctaaaaagaaaaat
ggaaactactgtgtccttcagatggaccagtcttacaaaccagatgaaaatgaagttcga
actctcttcggtcttcgtttaagccagaagagaaataacggtgtcatcgacaggtcatta
tttagcaatgttgttaccaagaataaagatttgccggaatctgccctccgagacctcatt
gtggccaccattgctgtcaagtatactcagtctaactcagtgtgctatgccaagaatggg
caggttatcggcattggagcaggacagcagtctaggatacactgcacacgacttgcagga
gacaaggcaaactactggtggctcagacaccatccacaagtgctttcgatgaagtttaaa
acaggagtgaagagagcagaaatctccaatgccatcgatcagtatgtgactggaaccatc
ggcgagggtgaagatttgataaagtggaaggctctgtttgaggaagtccctgaactacta
actgaggcagagaagaaggaatggattgacaggctaagtgaagtttctgtcagctccgat
gccttcttccctttcagggataatgtagacagggccaaaaggagtggcgtggcgtacatt
gctgctccctcaggctctgctgcagacgaagttgtgattgaggcttgcgatgagctggga
ataatactcgcccatacaaaccttcggctgttccaccactga
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