Galeopterus variegatus (Sunda flying lemur): 103596182
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Entry
103596182 CDS
T08727
Symbol
PKLR
Name
(RefSeq) pyruvate kinase PKLR isoform X1
KO
K12406
pyruvate kinase isozymes R/L [EC:
2.7.1.40
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr00010
Glycolysis / Gluconeogenesis
gvr00620
Pyruvate metabolism
gvr01100
Metabolic pathways
gvr01200
Carbon metabolism
gvr01230
Biosynthesis of amino acids
gvr04910
Insulin signaling pathway
gvr04930
Type II diabetes mellitus
gvr04932
Non-alcoholic fatty liver disease
gvr04950
Maturity onset diabetes of the young
Module
gvr_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
gvr_M00002
Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
103596182 (PKLR)
00620 Pyruvate metabolism
103596182 (PKLR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
103596182 (PKLR)
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
103596182 (PKLR)
04950 Maturity onset diabetes of the young
103596182 (PKLR)
04932 Non-alcoholic fatty liver disease
103596182 (PKLR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
gvr04147
]
103596182 (PKLR)
Enzymes [BR:
gvr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.40 pyruvate kinase
103596182 (PKLR)
Exosome [BR:
gvr04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
103596182 (PKLR)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PK
PK_C
HpcH_HpaI
IMPDH
Motif
Other DBs
NCBI-GeneID:
103596182
NCBI-ProteinID:
XP_008577987
LinkDB
All DBs
Position
Unknown
AA seq
574 aa
AA seq
DB search
MSSQENILSQKLWSCISKSQRDLANSILIGAPGGPAGYLRRASVAQLTQELGTAFFQQQQ
LSAAMADTFLEHLCLLDIDSEPVVARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFS
HGSHEYHAESIANVREAVESFATSPLSYRPVAIALDTKGPEIRTGILLGGPDSEVELVKG
SQVLVTVDPAFRTRGDANTVWVDYPNIVRVVPMGGRIYIDDGLISLVVQKIGPEGLATEV
ESGGVLGSRKGVNLPGALVDLPGLSEQDVRDLRFGVDHGVDIVFASFVRKASDVAAVRDA
LGPEGQGIKVISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC
NLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGKFPVEAVKM
QHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEITAIGAVEAAFKCCAAAIIVLTTTGRS
AQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEATWADDVDRRVQFGIESG
KLRGFLRTGDLVIVVTGWRPGSGYTNIMRVLSVS
NT seq
1725 nt
NT seq
+upstream
nt +downstream
nt
atgtcaagccaggagaacatactatcccagaagctttggtcatgtatctctaagtcccaa
agagacttagcaaactccatcctgattggagctccaggagggccagcggggtacctgcgg
cgggccagtgtggcccaactgacccaggagctgggcactgccttcttccagcagcagcag
ctatcagctgctatggcagacaccttcctggaacacctctgcctgctggacattgactct
gagcctgtggtcgctcgtagcaccagcatcattgccaccatcgggccggcatctcgttcc
gtggagcgcctgaaggagatgatcaaggccgggatgaacattgcgcgactcaacttctcc
cacggctcccacgagtaccacgctgagtccatcgccaatgtgcgggaggcggtggagagc
tttgcaacttccccgctcagctaccggcccgtggccatagctctggacactaaaggaccg
gagatacgcactgggatcctgctggggggcccggactcggaagtggagctggtgaagggc
tcccaggtgctggtgactgtggacccggcgttccggacgcggggggacgcgaacaccgtg
tgggtggactaccccaatatcgtccgggtcgtgccgatggggggccgcatctatatcgac
gacgggctcatctccctggtggtccagaaaatcggcccagaggggctggcgaccgaagta
gagagcggtggcgtcctgggcagccggaagggcgtgaacttaccaggcgccctggtggac
ctccccgggctgtccgagcaagatgtccgggacctgcgcttcggggtggatcatggcgtc
gacatcgtctttgcctcctttgtgcggaaagccagcgatgtggctgccgtccgggatgct
ctgggaccggaaggacagggcatcaaagtcatcagcaaaattgagaaccacgaaggcgtg
aagaagtttgatgaaatactggaggtgagcgacggcatcatggtggcgcggggggacctg
ggcattgagatcccagcagagaaggttttcctggctcagaagatgatgatcgggcgctgc
aacttggcgggcaagcccgttgtctgtgccacacagatgctggagagcatgatcaccaag
ccccggccaacacgggcagagaccagcgatgtggccaatgctgtgctggatggggcagac
tgcatcatgctgtcgggggagactgccaagggcaaattccctgtggaggctgtgaaaatg
cagcatgcgattgcccgggaggcagaggccgcagtgtaccacaggcagctgtttgaggag
ctacgccgggcagcaccgctgagccgtgatcccactgagatcactgccattggtgctgtg
gaggctgccttcaagtgctgtgctgctgccatcatcgtgctgaccacaactggccgctca
gcccagcttctgtcacggtaccgacctcgggcagcagtcattgctgtcacccgttctgcc
caggctgcccgccaggtccatctatgccgaggagtctttcccttgctctaccgtgaacct
ccagaggctacctgggcagacgatgtggatcgccgggtccaatttggcattgaaagtgga
aaactccgtggcttcctccgtactggggacctggtgattgtggtgacaggctggcgacct
ggctctgggtataccaacatcatgcgggtgctgagtgtgtcctga
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