Galeopterus variegatus (Sunda flying lemur): 103596635
Help
Entry
103596635 CDS
T08727
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
103596635 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
gvr03032
]
103596635 (TOP2B)
03036 Chromosome and associated proteins [BR:
gvr03036
]
103596635 (TOP2B)
Enzymes [BR:
gvr01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
103596635 (TOP2B)
DNA replication proteins [BR:
gvr03032
]
Eukaryotic type
DNA Topoisomerases
103596635 (TOP2B)
Chromosome and associated proteins [BR:
gvr03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
103596635 (TOP2B)
Centrosome formation proteins
Centriole proteins
103596635 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
103596635
NCBI-ProteinID:
XP_008578519
LinkDB
All DBs
Position
Unknown
AA seq
1543 aa
AA seq
DB search
MWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPESNIISIWN
NGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKLDKDIVALMT
RRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHELANERWDVC
LTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVKPFQVKNHI
WIFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILNWVKFKAQ
TQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGVIGRDR
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIPEFDEWRK
HIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDD
RKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVD
GFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNN
INLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDNLLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNYKNFKGTIQ
ELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEY
HTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILK
EFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQR
GYESDPVKAWKEAQEKAAEEEETPNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEE
LIKQRDSKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDIMAGMSGKAIKGKVG
KPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDIDTTAVKVEFDEEFSGI
PVEGTGEEALTPSAPINKGSKPKREKKDPGTRVRKTPTSSGKPTAKKMKKRNPWSDDESK
SESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDNNDLEELKVKASPI
INDGEDEFVPSDGLDKDEYTFSPGKSKSTPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSA
KFDSNEEDSASVFSPSFGLKQTDKIPSKTVAAKKGKPSLDTAPKPKRTPKQKKVVETVNS
DSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTASKKPKKTSFDQDSD
VDIFPSDFTSEPPSLPRTGRARKEIKYFAESDEEEDVDFAMFN
NT seq
4632 nt
NT seq
+upstream
nt +downstream
nt
atgtgggtgtatgatgaagatgtgggaatgaattgcagagaggttacctttgtgccgggt
ttatacaagatctttgatgaaattttggttaatgctgctgacaataaacagagggataag
aacatgacctgtattaaagtttctattgatcctgaatctaacattataagcatttggaat
aatgggaaaggcatcccagtagtagaacacaaagtagagaaagtttatgttcctgcttta
atttttggacaacttttaacatccagtaactatgatgatgatgagaaaaaagttacaggt
ggtcgcaatggttatggtgcaaaactttgtaatatattcagtacaaagtttacggtagaa
acggcttgcaaagaatacaaacatagttttaagcagacatggatgaataatatgatgaag
acttctgaagccaaaattaaacattttgatggtgaagattacacatgtataacattccaa
ccagatctgtccaaatttaagatggaaaaacttgacaaggatattgtggccctcatgacc
agaagagcatatgatttggctggttcgtgtaaaggggtcaaagtcatgtttaatggaaag
aaattgcctgtaaatggatttcgcagttatgtagatctttacgtgaaagacaaattggat
gaaactggggtggccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgt
ctcacattgagtgaaaaaggattccagcaaatcagctttgtaaatagtattgcaactaca
aaaggtggacgccatgtggattatgtagtagaccaagttgttggtaaactgattgaagta
gttaagaaaaagaacaaagctggtgtatcagtgaaaccatttcaagtaaaaaaccatata
tggatttttattaattgccttattgaaaatccaacttttgattcccagactaaggaaaac
atgacactgcagcccaaaagttttgggtccaaatgccaactgtcagaaaaattttttaaa
gcagcctctaattgtggtattgtagaaagtatcctgaactgggtgaaatttaaggctcag
actcagctgaacaagaagtgttcatcagtaaaatatagtaaaatcaaaggtattcccaag
ctggatgatgctaatgatgctggtggcaaacattctctggagtgtacactgatattaaca
gagggagactctgccaaatcactggctgtgtctggattaggtgtgattgggcgagacaga
tatggagtctttccactcaggggtaaaattcttaatgtacgggaagcttctcataaacag
atcatggaaaatgccgaaataaacaatattattaaaatagttggtctacaatataagaaa
agttatgatgatgcagaatctctgaaaaccttacgctatggaaagattatgattatgact
gatcaggatcaagatggttctcacataaaaggcctgcttattaatttcatccatcacaat
tggccatcacttttgaagcatggttttcttgaagaatttattactccaattgtaaaggcg
agcaaaaataagcaggaactttccttctacagtattcctgaatttgatgagtggagaaaa
catatagaaaaccagaaagcctggaaaataaaatactacaaaggattgggtaccagtaca
gctaaagaagcaaaggagtattttgctgatatggaaagacatcgcatcttgtttagatat
gctggtcctgaagatgatgctgccattaccttggcattcagtaagaagaagattgatgac
agaaaagaatggttaacaaattttatggaagatcggagacagcgtaggttacatggctta
ccagagcaatttttatatggtacagcaacaaagcatttgacttacaatgatttcatcaac
aaggaattgattctcttctcaaactcagacaatgaaagatctataccatctcttgttgat
ggctttaaaccaggccaacgaaaagttttatttacctgtttcaagaggaatgataaacgt
gaagtaaaagttgcccagttggctggatctgttgctgagatgtctgcttatcatcatgga
gaacaagctctgatgatgactattgtgaatttggctcagaactttgtgggaagtaacaat
attaacttacttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgct
gcaagccctcgttatattttcacaatgttaagctctttagcaagactactttttcctgct
gtggatgacaacctgcttaagttcctttatgatgataaccaacgtgtagagcctgagtgg
tatattcccataattcccatggttttaataaatggtgctgagggcattggtactggatgg
gcttgtaaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgcta
gatggcttggatcctcatcctatgcttccaaactataaaaacttcaaaggcacaatccaa
gaacttggtcaaaaccagtatgcagtcagtggtgaaatatttgtggtggataggaacaca
gtagaaattacagagcttccagttagaacttggacacaggtatacaaagaacaggtttta
gaacctatgctaaatggaacagacaaaacaccagcattaatttctgattataaggaatat
catactgatacaactgtgaaatttgtggtgaaaatgactgaagagaaactagcacaagca
gaagctgctggactgcataaagtttttaaacttcaaactactcttacttgtaattccatg
gtactctttgatcatatgggatgtctgaagaagtatgaaactgtgcaagacattctgaaa
gaattctttgatttacgattaagctattatggtctacgtaaggagtggcttgtaggaatg
ttgggagcagaatctacaaagcttaacaatcaagcccgtttcattttagaaaagatacaa
gggaaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccagaga
ggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagag
gaagaaaccccaaaccagcatgatgatagttcctctgattcaggaactccttcaggcccc
gattttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaa
ctgattaaacagagagattcaaaaggacgagaggtcaacgatcttaaaagaaaatctcct
tcagatctttggaaagaagatttagcagcatttgttgaagaactggataaagtagaagcg
caggaacgagaagatattatggctggaatgtctggaaaagcaataaaaggtaaagttggt
aaacctaaggtgaagaaacttcagttggaagagacaatgccctcaccttatgggagaagg
ataattcctgaaattacagctatgaaggcagatgccagcaaaaagttgctgaagaagaag
aagggtgatattgataccacagcagtaaaagtggaatttgatgaagaattcagtggaata
ccggtagaaggtacaggagaagaggcattgaccccttcagctcctataaataaaggttcc
aaacccaaaagggagaaaaaggatcctggtacaagggtaagaaaaacacctacatcatct
ggtaaacccactgcaaaaaaaatgaagaaacggaatccttggtcagatgatgaatccaag
tcagaaagtgacttggaagaaacagaacctgtggttattccaagagattctttgcttaga
agagcggctgctgaaagacctaagtacacatttgatttctcagaagaggaggatgatgat
gctgatgatgatgatgacaataatgatttagaggaattgaaagttaaagcatctcccata
ataaatgatggggaagatgaatttgttccttcagatggcttagataaagatgaatataca
ttttcaccaggcaaatcaaaatctactccagaaaaatctttgcatgacaaaaaaagtcag
gattttgggaatctcttctcatttccttcatactctcagaagtcagaagatgattcagct
aaatttgacagtaatgaagaagattctgcttctgttttttcaccatcatttggtctgaaa
caaacagataaaattccaagtaaaacagtagctgctaaaaaaggaaaaccatctttggat
acagctcctaagcccaagagaacccccaaacagaaaaaagtagtagagactgtaaactcc
gactcagattcagaatttggcattccaaagaagactacaacaccaaaaggtaaaggccga
ggggcaaagaaaaggaaagcatctggctctgaaaatgaaggtgattataaccctggcagg
aaaacatccaaaacagcaagcaagaaaccgaagaaaacttcttttgatcaggattcagat
gtggacatcttcccctcagacttcacttctgaaccaccttctctgccacggaccgggcgg
gctaggaaagaaataaaatattttgcagagtctgatgaagaagaagatgttgattttgca
atgtttaattaa
DBGET
integrated database retrieval system
