Galeopterus variegatus (Sunda flying lemur): 103597845
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Entry
103597845 CDS
T08727
Symbol
TSC2
Name
(RefSeq) tuberin isoform X1
KO
K07207
tuberous sclerosis 2
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr04072
Phospholipase D signaling pathway
gvr04115
p53 signaling pathway
gvr04140
Autophagy - animal
gvr04150
mTOR signaling pathway
gvr04151
PI3K-Akt signaling pathway
gvr04152
AMPK signaling pathway
gvr04211
Longevity regulating pathway
gvr04218
Cellular senescence
gvr04714
Thermogenesis
gvr04910
Insulin signaling pathway
gvr04919
Thyroid hormone signaling pathway
gvr05163
Human cytomegalovirus infection
gvr05165
Human papillomavirus infection
gvr05168
Herpes simplex virus 1 infection
gvr05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04072 Phospholipase D signaling pathway
103597845 (TSC2)
04151 PI3K-Akt signaling pathway
103597845 (TSC2)
04152 AMPK signaling pathway
103597845 (TSC2)
04150 mTOR signaling pathway
103597845 (TSC2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103597845 (TSC2)
09143 Cell growth and death
04115 p53 signaling pathway
103597845 (TSC2)
04218 Cellular senescence
103597845 (TSC2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
103597845 (TSC2)
04919 Thyroid hormone signaling pathway
103597845 (TSC2)
09149 Aging
04211 Longevity regulating pathway
103597845 (TSC2)
09159 Environmental adaptation
04714 Thermogenesis
103597845 (TSC2)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
103597845 (TSC2)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
103597845 (TSC2)
05163 Human cytomegalovirus infection
103597845 (TSC2)
05165 Human papillomavirus infection
103597845 (TSC2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
gvr01009
]
103597845 (TSC2)
Protein phosphatases and associated proteins [BR:
gvr01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
103597845 (TSC2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Tuberin
DUF3384
Rap_GAP
Cnd1
Motif
Other DBs
NCBI-GeneID:
103597845
NCBI-ProteinID:
XP_008579925
LinkDB
All DBs
Position
Unknown
AA seq
1814 aa
AA seq
DB search
MAKPTNKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSVESGLNNRIRV
IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPPEARHAVLALLKAIVQGQGDRLGVLR
ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWMDVGLSSEFLLVL
VNLVKFNSCYLDEYIASMVHMICLLCIRTMSSVDIEVSLQVLDAVVCYNCLPAESLPLFI
VTLCRTVNVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMEDAPLLRGAVFFVG
MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRKELQAVTWDI
LLNIIHRLLQQLQSLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE
SSLLNLISYRAQSIHPAKDGWIQNLQLLMERFFRNESRSAVRIKVLDILSFVLLINRQFY
EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS
PPPELEEKDVAAYSASLEDVKTAVLGLLLILQTKLYTLPASHAVRVYETLVSHIQLHYKH
SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGAVRFSPYCLCDYTEPERGSEKKAS
GPLSPPTGPPGPMPAGPTIRLGYLPYSLLFRVLLQCLKQETEWKVLKLVLSKLPESLRYK
VLIFTSPCSVDQLSSALCSMLSGPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL
DKTKQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMA
IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC
RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGWNNS
PPVKECKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHL
ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL
LGLDSGELQGGPESSSDPGVHVRQTKEAPAKLESQAGQQLSRGARDRVRSMSGGHGLRVG
ALDVPASHFPGGSTSPGPQTPPATKPEKASAGAQTPAQEKKNLAAYVPLLTQGWAEILVR
RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAST
AKSPTLPRSNTVASFSSLYQSSCQGKLHRSISWADSAVVLEEGGPGEAHASMEPPELEDF
EAALGTDRHCGHAEAYSRSSSTSSQEEKSFRAEELAAGAIPIERAVSSEGDQSSVDLSFQ
PSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEAKTRSQSGILDGEGAAWSAPGEES
RGLGLAQPESPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDAFKSRAAASNAEKVP
GINPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQS
SSELAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIM
QAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIRGQFNFVHVIITP
LDYQCNLVSLQCRKDMEGLVDTSMAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDI
YPSKWIARLRHIKRLRHRIREEAHYSNPSLPLMQMHPPAHTKAPAPSPPEPTPTYETGQR
KRLISSVDDFTEFV
NT seq
5445 nt
NT seq
+upstream
nt +downstream
nt
atggccaagccaacaaacaaagattcaggcttgaaggagaagttcaagattctgttggga
ctgggaacaccaaggccgaaccccaggtctgcagagggcaaacagacggagtttatcatc
acggcggaaatcctgagagaactgagtgttgaaagtggcctcaacaatcgcatccgggtg
atagggcagatctgtgaagtcgcaaaaactaagaagtttgaagagcatgccgtggaagca
ctctggaaggccgtcgcagacttgctgcagccggagcggccgccagaggcccggcacgca
gtgctggctctgctgaaggccattgtgcaggggcagggtgaccgcctgggggtcctcaga
gccctcttctttaaagtcatcaaggattacccctccaatgaagacctccacgaaaggctg
gaagttttcaaggccctcacggacaatgggagacatatcacctacctagaagaagaactg
gccgagtttgtcctgcagtggatggatgtcggcttgtcctcagaattccttctggtgctt
gtgaacttggtcaaattcaatagctgttacctcgacgaatacatcgcctccatggttcac
atgatctgcctgctgtgtatccggaccatgtcctctgtggacatagaggtctccttgcag
gtgctggacgctgtggtctgctacaattgcctgccggccgagagcctgccactgttcatt
gtcaccctgtgccgcacggtcaacgtcaaggagctctgtgagccctgctggaagctgatg
cgtaacctcctgggcacccacctgggccacagcgccatctacaacatgtgccgcatcatg
gaggacagagcctacatggaagacgccccgctgctgagaggagccgtgttctttgtgggc
atggctctctggggtgcccaccgactctattctctcaagaactccccgacgtctgtgtta
ccgtcgttttatgaggccatgacctgtccgaacgaggtggtgtcctatgagatcgtcctg
tccatcaccagactcatcaagaagtataggaaggagctccaggcggtgacgtgggacatc
ctgctgaacatcatccataggctgttgcagcagctccagagtctggacagcccggagctc
aggaccattgtccacgacctgctgaccacggtggaggagctgtgtgaccagaatgagttc
cacggctcccaggagagatactttgagctggtggagagatgcgcagaccagaggcctgaa
tcctccctcttgaacttaatatcctacagagcccagtcaattcacccggcaaaggatggc
tggattcagaacctgcagctgttgatggagaggttcttcaggaacgagtcccgcagtgca
gtgcgcatcaaggtgctggacatcctgtccttcgtgctgcttatcaacaggcagttctat
gaggaggagctgatcaactcggtggtgatctcgcagctctcccacatccctgaggataag
gaccaccaagtgcggaagctggccacgcagctgctggtggacctggcagagggctgccac
acccaccacttcaacagcctactggacatcattgagaaagtgatggcccgctcactctct
ccaccccccgagctggaggaaaaggacgtggccgcctactcggcttccttggaagatgtg
aagactgcggtcctggggctgctgctcatccttcagactaagctgtatacgttgcctgcc
agccatgctgtgcgcgtgtatgagacgcttgtcagtcacatccagctccactacaagcac
agctacaccctgcccattgccagcagtatccggctgcaggcctttgactttctgctgctg
ctgcgggctgactcgctgcaccgcctcggccttcccaacaaggacggggctgtgagattc
agcccctattgcctctgtgactacacggagccggagagaggctccgagaagaaggccagt
ggccccctttcgccccccactgggccacctggccccatgcctgcaggccccactattcgg
cttggctacctgccgtactccctgctcttccgagtcctgctgcagtgtttgaagcaggag
accgagtggaaggtgctgaagctggtcctcagcaagcttcccgagtcactgcgctacaag
gtcctcatcttcacctctccctgcagcgttgaccagctgtcttctgccctctgctccatg
ctttcaggcccaaagacccttgagcggctgcgaggcaccccagaagggttctccagaacc
gacctgcacttggccgtggttccagtgctgacagcattaatctcctaccataactactta
gacaaaaccaaacagcgggagatggtgtactgcctggagcaaggtctcatctaccgctgc
gctagccagtgtgtggtggccctggccatctgcagcgtggagatgcccgacatcatcatc
aaagcactgcccgttctcgtggtgaagctcacacacatctcagccactgccagcatggcc
atcccgctgctggagttcctgtccactcttgccaggctgcctcacctctacaggaacttc
gctgcagagcagtacgccagtgtgtttgccatctccctgccatacaccaacccctccaag
ttcaatcagtacatcgtgtgcctggcccatcatgtaatagccatgtggtttatcagatgc
cgcttgcccttccggaaagattttgttccttatatcactaagggcctgcgttccaatgtc
ctcctgtcttttgatgacacacctgagaaggacagcttcagagcacggagcaccagtctc
aacgagaggcccaaaagtttgaggatagccagaccccccaaacaaggctggaataactct
ccacctgtgaaagagtgcaaggagagctctgcagccgaggccttccggtgccgcagcatc
agtgtgtctgaacatgtggtccgcagcaggatacagacatccctcaccagtgccagcctg
ggatctgcagatgagaactccatggctcaggcagacgacaacttaaaaaatctccacctg
gagctcacagaaacatgtctggacatgatggcccgatatgtgttctccaacttcacggca
gtccccaagaggtctcctgtgggagagttcctcctggcaggcggcaggaccaagacgtgg
ctggttgggaacaagcttgtcaccgtgacgacaagtgtggggactgggacccggtcattg
ctgggcctagactcaggggagcttcagggcggcccagagtcaagctctgaccccggagtg
catgtgcgacagacaaaggaggcgccggccaagctggagtcccaggctggacagcagctg
tcccgcggggcccgggaccgggtccgctccatgtcggggggccatggccttcgagttggt
gccctggacgtgcccgcctcccacttcccaggtggctccacttctccaggaccacagact
ccaccagccacaaagcccgagaaggcctcagcgggcgcccagactccagcacaggagaag
aaaaacctggcggcctacgtgcccctgctaacccagggctgggcagagatcttggtccgg
aggcccacagggaacaccagctggctcatgagcctggagaacccactcagccccttctcc
tcggacatcaacaacatgcctctgcaggagctgtccaatgccctcatggcggctgaacgc
ttcaaggagcaccgggacacagccctgtacaagtcgctgtcagttccagcagccagcacg
gccaagtcccccactctcccacgctccaacacagtggcctctttctcctccctgtaccag
tccagttgccaaggaaagctgcacaggagcatttcctgggcagactctgccgtggttttg
gaggagggaggtccaggagaagctcatgcatcaatggagccccctgagttggaggacttc
gaggcagctctgggcacagacaggcactgtgggcacgctgaggcctacagcaggtcatcc
tcaacctctagccaggaggagaagtcattccgtgcagaagagctggctgctggggccatt
cccatcgagcgggccgtctcctctgagggagaccagtcctctgtggacctctccttccag
ccctcacagcccctgagcaagtccagctcctcgcccgagctgcagaccctgcaagacatc
cttggggaccctggggacaaggctgatgttggccggctcagtcctgaagccaagacccgg
tcacagtcagggatcctggatggggaaggtgctgcttggtcagccccaggcgaagagagc
cggggtctgggccttgcccagcccgagagtcccttgccttccagctccccccgctcaccc
agtggccttcggccgcgaggttacaccatctctgattcggccccatcacgcaggggcaag
agagtagagagggatgccttcaagagcagagctgcagcctccaatgctgagaaagtgccg
ggcatcaaccccagcttcgtcttcctacagctgtaccattcgcctttctttggtgatgag
tccaacaagccaatcctgttgcccaacgagtcctttgagcggtcggtgcagcttcttgat
cagatcccgtcctacgacacacacaagattgctgtcctgtatgtgggagaaggtcagagc
agcagcgagcttgccatcctttccaacgagcacggctcctacaggtacacagagttcctg
acaggcctgggcaagcttatcgagctcaaggactgccagccagataaggtgtacctgggt
ggcctggatgtgtgtggcgaggacggccagttcacgtactgctggcatgatgacatcatg
caagctgtcttccacattgccaccctgatgcccaccaaggacgtggacaagcaccgctgt
gacaagaagcgccacctgggcaacgactttgtttccattgtctacaatgactctggcgag
gacttcaagctgggcaccatcagaggccagttcaacttcgtccacgtgatcatcaccccc
ctggactaccagtgcaacctggtgtcgctgcagtgcaggaaagatatggagggcctcgtg
gacaccagcatggccaagatcgtgtctgaccgcaacctgcccttcgtggcccgccagatg
gcactgcatgcaaatatggcctcacaggtgcaccacagccgctccaaccccactgacatc
tacccctccaagtggattgcccggctccgccacattaagcggcttcgccaccggatccgt
gaggaagcccactactcgaaccccagcctgcccctgatgcaaatgcaccctccagcccac
accaaagccccagcgcccagcccacctgagcccacgcccacctacgagactggccagcgg
aagcgcctcatctcttccgtggatgacttcacagagtttgtgtga
DBGET
integrated database retrieval system
