Galeopterus variegatus (Sunda flying lemur): 103598775
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Entry
103598775 CDS
T08727
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr00230
Purine metabolism
gvr01100
Metabolic pathways
gvr04927
Cortisol synthesis and secretion
gvr04934
Cushing syndrome
gvr05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103598775 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
103598775 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
103598775 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103598775 (PDE8A)
Enzymes [BR:
gvr01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
103598775 (PDE8A)
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Paralog
GFIT
Motif
Pfam:
PDEase_I
PAS_9
PAS
PAS_3
HTH_Mga
Motif
Other DBs
NCBI-GeneID:
103598775
NCBI-ProteinID:
XP_008581056
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All DBs
Position
Unknown
AA seq
590 aa
AA seq
DB search
MGYQSGELVGRKLSEVSINEKKAELLDTINSCIKIGKEWQGIYHAKKKNGDSVQQNVKII
PVIGQGGKIRHYVSIIRVCNGSNEAEKIPEYVQSDTCTDNQTGKHKDRRKGSLDIRTVAS
RASEVSSQRRHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTEALGRVLDILRTTEL
YSPQFGAKDDDPHANDLVEGLMSDGLRRLSGNEYVLSAKNLPQVSSSIITPMSLHDVPPR
IAQAMENEEYWDFDIFELEAATHNRPLIYLGLKMFARFGICEFLNCSESTLRSWLQIIEA
NYHSSNPYHNSTHSADVLHATAYFLSKERIKQTLDPIDEVAALIAATIHDVDHPGRTNSF
LCNAGSELATLYNDIAVLESHHAALAFQLTTRDDKCNIFKNMKRNDYRTLRQGIIDMVLA
TEMTKHFEHVNKFVNSINKPLAALEEDGETGKDQETINTMLRTPENRTLIKRMLIKCADV
SNPCRPLEYCIEWAARISEEYFSQTDEEKQQDLPVVMPVFDRNTCSIPRSQISFIDYFIT
DMFDAWDVFVDLPDLMQHLDNNFKYWKGLDDMKLRSLRPPPEEGKTLPGP
NT seq
1773 nt
NT seq
+upstream
nt +downstream
nt
atgggctatcagtcaggtgaattagtagggagaaagttatcagaagtgtctataaatgaa
aaaaaggctgagttgctggatactataaattcatgcatcaagataggcaaggagtggcaa
ggaatttaccatgccaaaaagaaaaacggagatagtgtgcaacaaaatgtgaagataata
cctgtcattggacagggaggaaaaattagacactatgtgtccattatcagagtgtgcaat
ggcagcaacgaggccgagaaaatacctgaatatgttcagtctgacacttgtacagataat
cagacaggcaaacataaagacaggaggaaaggctcactagacatcagaactgttgcctct
cgagcaagtgaagtttccagccagagacgacactcctccatggcccggatacattccatg
accattgaggcacccatcaccaaggtaatcaatatcatcaatgccgcccaggaaagcagc
cctatgcctgtgacagaagccttaggccgtgtgctggatattctaagaaccactgaatta
tattcaccacagtttggtgctaaggatgatgatcctcatgccaatgacctcgttgagggc
ttaatgtctgatggtttgcggagactatcagggaatgaatatgttctttcagcaaaaaac
cttccacaggtttcaagcagtataatcactcccatgtctcttcatgacgtcccaccgcgg
atagctcaagccatggaaaatgaggaatattgggactttgatatttttgaactggaggct
gccacccataataggcctttgatttatcttggtctcaaaatgtttgctcgctttggaatc
tgtgaattcttaaactgctccgagtcaacactgagatcgtggttacaaattattgaagcc
aattatcattcttctaacccctaccacaattctacacattctgctgatgtgcttcatgcc
actgcctattttctctccaaggagaggataaagcaaactttagatccaattgatgaagtc
gctgccctcattgcagccaccattcatgatgtggatcaccctgggagaaccaactccttc
ctgtgtaatgctggaagtgagctggccactttgtacaatgacattgctgtgttggagagc
caccatgcagccttggccttccagctgaccactagagatgataaatgcaatatctttaag
aacatgaagaggaatgactatcggacactacgccaggggattattgacatggtcctagcc
acagaaatgacaaagcacttcgagcatgtcaacaaatttgtcaatagcatcaacaagccc
ttggcagctctagaagaagatggggaaactggtaaagatcaggaaaccataaacactatg
ctcagaactccagagaacaggactctaattaaacgaatgctaattaagtgtgctgatgtg
tccaatccctgccgaccgctggagtactgcattgagtgggccgcccgcatttcagaagaa
tatttttctcagactgatgaagagaagcagcaggatttacctgtggtgatgccagttttt
gacagaaatacctgcagcatccccagatcccaaatctctttcattgactacttcatcaca
gacatgttcgatgcttgggatgtctttgtagacctgcctgatttaatgcagcatcttgac
aacaactttaaatactggaaaggactggacgatatgaagctgcggagcctccgaccacct
cctgaagagggcaagacactgcctggaccctga
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