Galeopterus variegatus (Sunda flying lemur): 103601162
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Entry
103601162 CDS
T08727
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr00310
Lysine degradation
gvr01100
Metabolic pathways
gvr05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
103601162 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
103601162 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
gvr03036
]
103601162 (DOT1L)
Enzymes [BR:
gvr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
103601162 (DOT1L)
Chromosome and associated proteins [BR:
gvr03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
103601162 (DOT1L)
HMT complexes
Dot1-containing complex
103601162 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
103601162
NCBI-ProteinID:
XP_008583760
UniProt:
A0ABM0RT19
LinkDB
All DBs
Position
Unknown
AA seq
1683 aa
AA seq
DB search
MENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQV
YNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVA
AATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIAN
TSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVV
ELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSNAT
TPTKVPESKVAGPTDATPMDSGAEEDKVGAATVKKPSPSKARKKKLNKKGRRMAGRKRGR
PKKMNTANPERKPRKNQTALDLLHAQTVSQTASSSPQDAYRSPHSPFYQLPPSVQRQSPN
PLLVAPTPPALQKLLESFKVQYLQFLAYTKTPQYKANLQQLLDQEKEKNAQLLGTAQQLF
SHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNCELR
SQSLQLLKARCEELKLDWSTLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQ
QELLHLKSCVPPDDSLSLHLRGKGSLGRELEAEPGRLHLELDCAKFSLPHLNSMSPELSM
NGHAAGYELCGTSSRPSSKQNTPQYLASPVDQEVVPCTPSHNGRQRLDKLSSLALPDYTR
LSPAKIVLRRHLSQDHAGSSKAAASELHPRADHIKENGLPYQSPGLSNSVKLSPQDLRPP
SPGALQMAAEKSSEKGLRERAHGSSGETITSLPISIPLSTVQPNKLPVSIPLASVVLPSR
AEKRSTPSPVPQPRDSVSALEKQSGANAHSAGSKSLALAPAGFSYTGSVAISGALAGSPA
PLVPGTEPAAFDESSNSGSLFATLGSRSSTPQHPPLLAQPRNSGPASPAHQLATSPRLSG
ATQGLLPDASKGDLTSDSGFSDPESEAKRRIVFSISAGAGSTKQSPSNKHSPLTSGTRGD
SGQGHGQDSRKRGRRKRSSAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNI
NQPLEITAISSPENSLKSSPIPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEDQGSEDE
PSSASRIERKIATISLESKSPPKTLENGSSVAGRKPMATGEPVNSSKWKSTFSPISDIGL
AKAADSPLQASSALSHNSLFSFRPAMEEPGADAKLSAHPRKSFPGSMSGADGLSPSTNPP
NGFAFSGGLAADLSLHSLNDGASLSHKVPEAASLSTPLSFPSQRGKEGASEANPFLNKRQ
LDGLGSLKGEGGKAKEVAELGLVLCGPVEKASLPHGSKAAKGRDRELDFKNGHNLFISAA
AVPPAGLLSGPGLASVSSASSAAPSTQTHRPFLGTFAPGPQFTLGPMSLQANLSSVAGSS
VLQSLFSSVPAAAGLVHVSSATTRLTNSHAMGNFSSGVAGGTVGGVFNHAVPSASARPFG
AGVGSGAVCSSVLLGLGPLQAAASTSASCFQAPASAESRPPPPPPPLPPPPHLGRAPVGP
PVLHAPPPPNVALPAASALLASNPAPVLLQSLAALPANHALSPPASAASLPPANASLSIQ
LAPLPHKGSRPSFTVHHQPLPRLALAQATPPLPQAGAAGPSAVWVSLGMPPPYAAHLAGV
KPR
NT seq
5052 nt
NT seq
+upstream
nt +downstream
nt
atggagaattacgttttaattgactatgataccaaaagcttcgaaagcatgcagaggctc
tgtgacaagtacaaccgggccatcgacagcatccaccagctgtggaagggcaccacgcag
cccatgaagctgaacacacggccgtccaacgggctgctccggcacatcctgcagcaggtg
tacaaccactcggtgacagacccagagaagctcaacaactacgaacccttctccccggag
gtgtatggggagacctcctttgacctggtggcccagatgattgatgagatcaagatgact
gaggatgatctgtttgtggacttgggcagtggtgtgggccaggttgtgctccaggttgcc
gcggccaccaactgcaaacatcactatggcgttgagaaagcggacatcccagccaagtac
gcggagaccatggaccgagagttcaggaagtggatgaaatggtatggaaaaaagcatgca
gaatacacactggaaaggggcgatttcctctctgaagagtggagagagcggatcgccaac
acaagtgttatatttgtgaataactttgcctttggtcctgaggtggatcaccagctgaag
gagcgatttgcaaacatgaaggaaggtggcagaatcgtgtcctcaaaaccttttgcacct
ctaaacttcagaataaacagcagaaacttgagtgacattggcaccatcatgcgggtcgtg
gagctgtcgcctctgaagggctccgtgtcgtggacggggaagccagtctcctactacttg
cacaccatcgaccgcaccatacttgaaaactatttttctagtctgaaaaatccaaaactc
agggaggaacaagaggcagctcggcgccggcagcagcgcgagagcaagagcaatgcgacc
acccccaccaaggtccccgagagtaaggtggccggccccacagacgccacccccatggat
tctggcgctgaggaagataaggtgggagcggccaccgtcaaaaagccgtccccctccaag
gcccggaagaagaagctgaacaagaaaggcaggaggatggctggccgcaagcgcgggcgc
cccaagaagatgaacactgcgaaccccgagcgcaagcccaggaagaaccaaaccgcactg
gacctcctgcacgcgcagaccgtgtcccagacagcgtcctcctcaccccaggatgcatac
aggtcacctcacagcccgttttaccagctacctccgagcgtgcagcggcagtcccccaac
ccgctgctggtggcacccaccccgcctgcgctgcagaagctgctagaatccttcaaggtt
cagtacctgcagttcctggcgtacacaaagacccctcagtacaaggccaacctgcagcag
ctgctcgaccaggagaaggagaagaacgcccagttgctgggcacggcgcagcagctcttc
agccactgccaggcccaaaaggaggagatcaggaggctcttccagcagaaactggatgag
ttgggcgtgaaggctctgacctacaatgacctgatccaagctcagaaggagatttctgct
cataaccagcagctgcgggagcagtcagagcagctggagaaagacaactgcgagctcagg
agtcagagcctgcagctgctcaaggctcggtgtgaagagctgaagctggactggtccaca
ctgtccctggagaagctgctgaaggagaagcaggccctgaagagccagatctcagagaag
caaaggcactgcctggagctgcagatcagcatcgtggagctggagaagagccagcggcag
caggagctcctgcacctcaagtcctgcgtgcctcccgacgattccctgtcgctgcacctg
cgcgggaaaggctccctgggccgtgagctggaggctgagcctggcaggctgcacctggag
ctggactgcgccaagttttctctgcctcacttgaacagcatgagcccggagctctccatg
aatggccacgcggccggctatgagctgtgtggcacgtcgagccggccctcgtccaagcag
aacaccccccagtacctggcctcccccgtggaccaggaggtcgtgccctgtacccccagc
cacaacggccggcagcggctggacaagctatccagcctggcccttcctgactacaccagg
ctctccccagccaagattgtgctgcggaggcacctgagtcaggaccatgcaggttccagc
aaggcggctgccagcgagctgcacccgcgagctgatcatatcaaggagaacggtcttccc
taccagagccctggtctgtccaacagcgtgaagctaagccctcaggacctgcggcctccg
tcccccggggccttgcagatggcagcggagaagagcagtgaaaagggactgagggagcga
gcccacggcagcagcggggagaccatcaccagcctgcccatcagcatcccgctgagcaca
gtgcagcccaacaagctccccgtcagcatccccctggccagcgtggtgctgcccagccgc
gccgagaagaggagcactcccagtcctgtaccgcagccccgggactccgtgtccgcactg
gaaaagcagagcggtgctaacgcccacagcgctgggagcaaaagccttgccctggctcct
gcaggcttctcctacaccggctcagtggccatcagcggggcgctggctggcagcccggca
cccctggtccccggcactgagccagcagcctttgacgagtcctctaactcggggagcctc
tttgccaccttggggtcccgcagctcgacgccacagcacccccctttgctggcacagccc
cgcaactccggcccagcctctccggcccaccagcttgccaccagtccccggctcagcggg
gccacccagggcctgctcccagatgctagcaagggggacctgacctctgattccggtttc
tcggacccagagagtgaagccaagaggagaatcgtcttcagcatctcggctggtgcaggc
agcaccaagcagtcaccttccaacaagcatagtcctctgacttcaggcacccgtggggac
agcgggcaaggccatgggcaggacagccgcaagcgtggccggcggaagcggtcgtcagct
gggacccccagcctgagtgcaggcgtgtctcccaagcgccgggccctgccttctgttgcc
ggcctcttcacacaaccttcagggtcccccctcaacctcaactccatggtcagcaacatc
aaccagccactggagatcacagccatctcgtccccagagaactccctgaagagctccccc
atcccctaccaggaccatgaccagcctcccgtgctcaaaaaggagcggcccctgagccag
accaatggcgcccactactccccgctgacctcggacgaagatcagggctctgaggatgag
cccagcagcgccagcagaattgagagaaaaatagcaacaatctccttagagagcaaatct
cccccaaaaaccttggaaaatggcagcagcgtggcgggaaggaagccgatggccacgggc
gagccggtcaacagcagcaagtggaagtccaccttctcgcccatctctgacatcggcctg
gccaaggccgccgacagcccgctgcaggccagctctgccctgagccacaactccctgttc
tccttccggcctgccatggaggagcctggtgccgacgccaagctcagtgcccaccccagg
aaaagctttcccggctccatgtcaggggccgatggtctcagcccgagcaccaaccctccc
aacggcttcgccttcagcgggggcctggccgcagacctcagtttacacagcctcaacgac
ggtgcttctctctcccacaaggtccccgaggcggccagtctgagcaccccgctaagcttt
ccctcccagcggggcaaagagggcgcctcggaggccaaccccttcctgaacaagaggcag
ttggacggcttgggcagcctgaaaggcgagggtggcaaggccaaagaggtggccgagctg
ggcctggtgctgtgtgggcctgtggagaaggcctccctgccgcatggcagcaaggcggcc
aagggccgggaccgtgagctcgacttcaagaacggccacaacctcttcatttccgccgcg
gcggtgcctcccgctggcctcctcagcggccctggcctggcctcagtgtcctctgcaagc
agcgcggcgccatccacgcagacgcaccgccccttcctgggcacttttgcccctgggcca
cagttcaccctgggccctatgtcgctgcaggccaacctcagctcggtggctggctcatcc
gtgctgcagtccttgttcagctctgtgccagccgccgcgggcctggtgcacgtgtcatcc
gccacaacccgactgaccaactcacacgccatgggcaacttctcctccggggtggctggc
ggaacagttggaggtgtctttaaccacgcggtgccttccgcctctgctcgcccgtttgga
gccggtgtcggcagcggcgctgtgtgcagcagtgtcctgctgggcctgggcccgctgcag
gcggcggccagcacctcggcctcttgctttcaggccccggcctcggccgagagtcggccg
ccccctccgcctcccccgctgcctccccctccgcacctgggccgggcccctgtggggccg
cccgtcctgcacgctcccccaccgcctaatgtcgccttgcctgctgcctccgcgctactg
gcctctaaccctgcgcctgtgcttctgcagagccttgcggccctccctgctaaccacgct
ctctcgccccctgcctctgctgcctcgctaccccctgctaacgcctctttgtctatccag
cttgccccgctcccgcacaagggctcccgcccctccttcacggtgcaccaccagcccctg
ccccggctggccctggcacaggccacacccccactcccgcaggctggcgccgcggggccg
tccgctgtgtgggtttcccttggcatgccgcctccttatgccgcacacctagcgggggtt
aagccgcgataa
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integrated database retrieval system
