Galeopterus variegatus (Sunda flying lemur): 103603263
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Entry
103603263 CDS
T08727
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr04140
Autophagy - animal
gvr04141
Protein processing in endoplasmic reticulum
gvr04210
Apoptosis
gvr04932
Non-alcoholic fatty liver disease
gvr05010
Alzheimer disease
gvr05012
Parkinson disease
gvr05014
Amyotrophic lateral sclerosis
gvr05016
Huntington disease
gvr05017
Spinocerebellar ataxia
gvr05022
Pathways of neurodegeneration - multiple diseases
gvr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
103603263 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103603263 (ERN1)
09143 Cell growth and death
04210 Apoptosis
103603263 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
103603263 (ERN1)
05012 Parkinson disease
103603263 (ERN1)
05014 Amyotrophic lateral sclerosis
103603263 (ERN1)
05016 Huntington disease
103603263 (ERN1)
05017 Spinocerebellar ataxia
103603263 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
103603263 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103603263 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
103603263 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gvr01001
]
103603263 (ERN1)
Enzymes [BR:
gvr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
103603263 (ERN1)
Protein kinases [BR:
gvr01001
]
Serine/threonine kinases: Other
IRE family
103603263 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
103603263
NCBI-ProteinID:
XP_008585976
LinkDB
All DBs
Position
Unknown
AA seq
1153 aa
AA seq
DB search
MRHNRGCELCDCPAQGRDSVFAGNPCQLLKPSRQRASQSTSPMTAPRREDEKGGFWAPGT
ARVPGPSPGGYGLSVLPSLGRASYLDPSPLLDAGRRGLVLLLSRRVRRTRASQRPRSGVR
CPSGLPGQRGCHGLGRNSVALGGTSVSPEGPGLREAAHLPDPPRSENQQQGEGLNLSPSR
PGTPKRWDERGSDSSFALLCQWIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTL
KEDPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGIL
YMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWN
ATYFDYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREG
LRKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLMPTLYVGKYSTSLYAS
PSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKNKLHDLR
NYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKNFEEVINLVDETSENAPTT
VSQGVGEKFAHAPAKPEAPMDSMLKDVATIILSTFLLIGWVAFIITYPLSMHQQQQHQQF
QKELEKIQLLQQQQLPFHPAGDATQDTELLDTSGPYSESSGTSSPSMSPRASNHSLQSAS
KAGTSLSLEQDDDDEETCMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPE
CFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLE
PITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHS
FSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGNHPFGKSLQRQAN
ILLGAYSLDCFHPEKHEDIIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQD
VSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAM
RNKRHHYRELPTEVRETLGALPDGFVRYFTSRFPHLLLHTYWAMELCGHERLFQPYYCHE
PPEPWPTVTPDAL
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgaggcacaaccgggggtgtgaactctgcgactgccctgctcagggcagagactccgtg
tttgctggaaacccctgccagctgctgaaaccatcgcgccaaagggcgtctcagtcaacc
tcgcccatgactgccccacggcgggaagacgaaaaggggggtttctgggcacccggtaca
gcccgtgtcccgggtccctcgcctggggggtacgggttgtcggtcttgcccagcctcgga
cgagcttcttacctagacccttccccgctcctggacgccggacgccgaggcctggtcctg
ctcctcagccgccgcgtccgcaggacccgagccagtcagaggccccgctcaggcgtccgc
tgccccagtggcctcccgggccagcgcggctgtcacgggctcgggcgcaactctgtggcc
ctgggcggcacctcggtatctccagaaggcccgggccttcgggaggccgcccacctgccg
gaccctccccgcagtgagaaccaacagcaaggcgaagggctgaacctctccccctccagg
ccaggtacacccaagagatgggatgagcgaggttctgacagctccttcgccctcctctgc
cagtggatttttggaagcaccagcacagtgacgcttcctgaaaccttgctgtttgtgtca
accctggatggcagtttgcatgctgtcagcaagaggacaggctcaatcaaatggacatta
aaagaagatccagtcctgcaggtcccaacacatgtggaagagcctgccttccttccagat
cccaatgatggcagcctgtatacgcttggaggcaagaataatgaaggcctgacaaaactt
ccctttactatcccagagttggtacaggcatccccttgccgaagttcagatggaattctg
tacatgggtaaaaagcaggacatttggtatgttatcgacctcctgaccggggagaagcag
cagactttgtcatcagcctttgcagacagtctctgcccatcaacctctcttctgtatctt
gggcgaacagaatacaccatcactatgtatgacaccaaaacccgagagctccggtggaac
gccacctactttgactacgcagcctcactgcctgaggacgacatggactacaagatgtcc
cactttgtgtccaatggtgatgggctggtggtgactgtggacagtgaatctggggacgtc
ctgtggatccaaaactatgcctcccctgtggtggccttttatgtctggcagcgggagggt
ctgaggaaggtgatgcacatcaacgttgctgtggagaccctgcgctatctgaccttcatg
tctggggaggtgggacgcatcaccaagtggaagtacccgttccccaaggagacggaggcc
aagagcaagctgatgcccaccctgtatgttgggaaatactctaccagcctctacgcctcc
ccctccatggtacatgaaggtgtcgctgtcgtgccccgcggcagcacgcttcctttgctg
gaaggcccccagactgatggtgtcaccattggggacaaaggagagtgtgtgatcaccccc
agcacggacctcaagttcgaccctggactcaaggggaagaacaagctccatgacttgagg
aactactggcttctgataggacaccatgaaaccccactgtctgcgtctaccaagatgctg
gagagatttcccaacaatctgccgaaacatcgggaaaatgtgattcctgctgattcggag
aagaactttgaggaggttatcaacctggttgacgagacttcggaaaacgcgcctaccacc
gtgtcccagggggtgggggagaagtttgctcatgcacctgccaagcccgaggcccccatg
gactccatgctcaaggacgtggccaccatcatcctgagcaccttcctgctcatcggctgg
gtggccttcatcatcacctaccccttgagcatgcatcagcagcagcagcaccagcagttc
cagaaggaactggagaaaatccagctcctgcaacagcagcagctgcccttccatccagct
ggagatgcgactcaggacaccgagctcttggacacatctgggccgtactcggagagctcg
ggcaccagcagccccagcatgtccccccgagcctccaaccactcactccaatctgcctct
aaggctggcacaagcctgtccctggagcaggatgacgacgatgaggaaacctgcatggtg
atagttgggaaaatttcattttgtcccaaagacgtcctgggtcacggagctgagggcacc
attgtgtaccggggcatgtttgacaaccgcgatgtggccgtgaagaggatcctccctgag
tgttttagctttgcagaccgtgaggtccagctgctgcgagagtcagacgagcacccaaac
gtgatccgttacttctgcacggagagggaccggcagttccagtacattgccatcgagctg
tgcgcagccaccttgcaagagtacgtggagcagaaggactttgcccacctcggcctggag
cccatcaccttgctacagcagaccacctcaggcctggcccacctgcactccctcaacatt
gttcacagagacctgaagccccacaacattctcctctccatgcccaatgcccatggcagg
atcaaggccatgatctctgactttggcctctgcaagaagctggcagtgggcaggcacagc
ttcagccgccgttctggggtgcccggcacagaaggctggattgctccggagatgctgagt
gaagactgcaaggagaaccctacctacacggtggacatcttctccgcgggctgcgtcttt
tactacgtgatctctgagggcaaccaccctttcggcaagtccctgcagcggcaggctaac
atcctcctgggtgcctacagcctcgactgcttccacccagagaagcacgaagacatcatt
gcacgtgaattaatagagaaaatgattgccatggatcctcagaaacgcccctcagcaaag
cacgtgctaaagcacccgttcttctggagcctggagaagcagctgcagttctttcaggat
gtgagtgaccgaatagaaaaggagtccctggatggcccaatcgtgaagcagttggagaga
ggcgggagagccgtggtgaagatggactggcgggagaacatcacagtccccctccagaca
gatctgcgtaaattcagaacctataaaggtggctcagtcagagatctcctccgagccatg
agaaacaagaggcaccactaccgggaactccccacggaggtgcgggagacgctgggcgcg
ctgcccgacggcttcgtgcgctacttcacctcacgcttcccccacctgctcttgcacacc
tactgggccatggagctgtgcggccacgagagactcttccagccctactactgccacgag
cccccggagccctggcccacagtgactccagatgccctctga
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integrated database retrieval system
