Galeopterus variegatus (Sunda flying lemur): 103604608
Help
Entry
103604608 CDS
T08727
Symbol
NF1
Name
(RefSeq) neurofibromin
KO
K08052
neurofibromin 1
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr01521
EGFR tyrosine kinase inhibitor resistance
gvr04010
MAPK signaling pathway
gvr04014
Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103604608 (NF1)
04014 Ras signaling pathway
103604608 (NF1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103604608 (NF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PH_NF1
RasGAP
CRAL_TRIO_2
CRAL_TRIO
MIF4G_like_2
Motif
Other DBs
NCBI-GeneID:
103604608
NCBI-ProteinID:
XP_008587402
LinkDB
All DBs
Position
Unknown
AA seq
2840 aa
AA seq
DB search
MYERPALGFRNVIAESMDEQSGGRLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVIS
GLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPE
ICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHD
IELLQYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQ
IPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNK
KLFLDSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNL
LFNPSKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHR
IITNSALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLK
FKEKPTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQS
HMPEIAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEI
LKWLREILICRNKFLLKNKQADRSSCHFLFLYGVGCDVPSSGNTSQMSMDHEELLRTSLR
KGKGNSSMDSTAGCGGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEADI
RCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWED
THAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWIN
MTGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRLL
SLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNTQ
FVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNLVHAIQIKTKLCQLV
EVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSL
LAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRLA
SLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAET
VLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWN
MFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSF
EVDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNK
ATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGL
KLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDSVNHSLSFI
SDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHW
SSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQIN
GDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYI
YNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLKV
FHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQF
TLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIAL
LNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANE
PHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLI
TMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALA
SGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAH
LPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLP
KFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRD
IPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCL
KGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLE
QNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYR
HPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRK
SLLLTDISMENVPMDTYPIHHGDPSYRTLKENQPWSSPKGSEGYLAASYPTVGQTSPRAR
KSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEM
ETQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRIL
YEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQ
TSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPT
SPYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSAS
QVQKQRSAGSFKRNSIKKIV
NT seq
8523 nt
NT seq
+upstream
nt +downstream
nt
atgtatgagagacctgctctggggttcaggaatgtcattgctgaaagtatggatgagcaa
agcggtgggagacttccaataaaaacaggacagcagaacacacataccaaagttagtact
gaacacaacaaggaatgtctgatcaatatttccaaatacaagttttctttggttataagc
ggcctcactactatcttaaagaatgttaacaatatgagaatatttggagaagctgctgaa
aaaaatttatatctctctcagttgattatattggatacactggaaaaatgtcttgctggg
caaccaaaggacacaatgagattagatgaaaccatgctggtcaaacagttgctcccagaa
atttgccattttcttcacacctgtcgtgaaggaaaccaacatgcagctgaacttcggaat
tctgcctctggggttttattttctctcagctgcaacaacttcaatgcagtctttagtcgc
atttctaccaggttacaggaattgactgtttgttcagaagacaatgttgatgttcatgat
atagaattgttacagtatatcaatgtggattgtgcaaaattaaaacgactgctgaaggaa
acagcatttaaatttaaagctctaaagaaggttgcacagttagcggttataaatagcctg
gaaaaggcattttggaactgggtagaaaattatccagatgaatttacaaagctataccag
attccacagactgatatggctgaatgtgcagaaaagctctttgacttggtggatggtttt
gctgaaagcaccaaacgtaaagcagcagtttggccactacaaatcattctccttattttg
tgtccagaaataatccaggatatatccaaggatgtggttgatgaaaacaacatgaataag
aagttgtttctggacagtctacgaaaagcacttgctggccatggaggaagcaggcagctg
acagaaagtgctgcaattgcctgtgtcaaactgtgtaaagcaagtacttacatcaattgg
gaagataactctgtcattttcctactagttcagtccatggtggttgatcttaagaatctg
ctttttaatccaagtaaaccattctcgagaggcagtcaacctgcagatgtggatctaatg
attgactgccttgtttcttgctttcgtataagccctcacaacaaccaacactttaagatc
tgcctggctcagaattcaccttctacatttcattatgtgctggtaaattcactccatcga
ataatcaccaattctgcattggattggtggcctaagattgatgctgtatattgtcactca
gttgaacttcgaaatatgtttggtgaaacacttcataaagcagtgcagggttgcggagca
cacccagcaattcgaatggcaccgagtcttacatttaaagaaaaagtaacaagccttaaa
tttaaagaaaaacctacggacctggagacaagaagctataagtatcttctcttgtccatg
gtgaaactaattcatgcagatccaaagctcttgctttgtaatccaagaaaacaggggcct
gaaacccaaggcagcacagcagaattaattacagggcttgtccaactggtccctcagtca
cacatgccagagattgctcaggaagcaatggaggccctgctggttcttcatcagttagat
agcattgatctgtggaatcctgatgctcctgtagaaacattttgggagattagctcacaa
atgcttttttacatctgcaagaaattaactagtcatcaaatgcttagtagcacagaaatt
ctcaagtggttgcgggaaattttgatctgcaggaataaatttcttcttaaaaataagcag
gcagatagaagttcctgtcactttctcttcctttatggggtaggatgtgatgttccttct
agtggaaataccagtcaaatgtccatggatcatgaagaattactgcgtacctctctccgg
aagggaaaaggaaattcctccatggatagtacagcagggtgtggtggaaccccaccaata
tgccgacaagcccagaccaaactagaagtggccctgtacatgtttctgtggagccctgac
actgaagctgttctggtagccatgtcctgtttccgccacctctgtgaggaagcggatatc
cggtgtggggtggatgaagtgtcagtacacaacttcttgcccaactataacacattcatg
gagtttgcttctgtcagcaatatgatgtcaacaggaagagcagcacttcagaaaagagtg
atggcactgctaaggcgcattgagcatcctactgcaggaaacactgaggcttgggaagat
acacatgcaaagtgggagcaagctacaaaacttattcttaactatccaaaagccaaaatg
gaagatggccaggctgccgaaagccttcacaagaccattgttaagaggcgaatgtcccat
gtgagtggaggaggatccatagatttgtctgatacagactccctgcaggagtggatcaac
atgactggcttcctttgtgcccttgggggtgtgtgcctgcagcagagaagcaattctggc
cttgcaacctatagcccacctatgggcccagtcagcgaacgtaagggttccatgatttca
gtgatgtcctcagagggaaacgcagatacacctgtcagcaaatttatggatcggctacta
tccttaatggtgtgtaaccatgagaaagtgggacttcaaatacggaccaatgttaaggat
ctggtgggtctagaattgagtcctgctctttatccaatgctgtttaacaagttgaagaat
accatcagcaagttttttgactcccaaggacaggtattattgactgacaccaatactcaa
tttgtagagcaaaccatagctataatgaagaacttactagataatcatactgaaggcagc
tctgaacatctgggacaagctagcattgaaacaatgatgttaaatctggtcagatatgtt
cgtgtgcttgggaatttggtccatgcaattcaaataaaaacaaaactgtgtcagttagtt
gaagtaatgatggcaaggagagatgacctctcattttgtcaagagatgaaatttaggaat
aagatggtagaatacttgacagactgggttatgggaacatcaaaccaagcagcagatgac
gatgtaaaatgtcttacaagagatttggaccaggcaagcatggaagccgtagtttcactc
ctggctggtcttccgctgcagcctgaggaaggagatggtgtggaattgatggaagccaaa
tcacagttatttcttaagtacttcacattatttatgaaccttttgaatgactgtagtgaa
gttgaagatgaaaatgcacaaacaggtggcaggaaacgtggcatgtctcggaggctggca
tcactgaggcactgtacagtccttgcaatgtcaaacttactcaatgctaatgtggacagt
gggctcatgcactcaataggtttaggttatcacaaggatctccagacaagagctacattt
atggaagttcttacaaaaatccttcaacaaggcacagaatttgacacacttgcagaaacg
gtgttggcagatcggtttgagagactggtggaactggtcacaatgatgggtgatcaggga
gagcttcctatagctatggctctggccaatgtggtcccttgttctcagtgggatgaacta
gctcgagttctggttactctatttgattctcggcatttactctaccaactgctctggaac
atgttttctaaggaagtagaattggcagactccatgcagactcttttccgaggcaacagc
ttggccagtaaaataatgacattctgtttcaaggtatatggtgctacctacctacaaaaa
ctcctggatcctttattacgaattgttatcacatcctctgactggcagcatgttagcttt
gaagtggatcctaccaggttagaaccatcagagagccttgaggaaaaccagcggaacctt
cttcagatgactgaaaagttcttccatgctatcatcagttcctcctcagagttcccgccc
cagcttcgaagtgtgtgccactgcttataccaggcaacttgccactccctactgaataaa
gctacagtaaaagaaaaaaaggaaaacaaaaaatcagtggttagccaacgtttccctcag
aacagcatcggtgcagtaggaagtgccatgttcctcagatttatcaatcctgccattgtt
tcaccatatgaagcagggattttagataaaaagccaccacctagaattgaaaggggcttg
aagttaatgtcaaagatacttcagagtattgccaatcatgttctcttcacaaaagaagag
catatgcggccttttaatgattttgtgaaaagcaactttgatgcagcacgaaggtttttc
cttgatatcgcatctgattgtcctacaagtgactcagtaaatcatagcctttccttcatc
agtgatggcaatgtgcttgctttacatcgtctgctttggaacaatcaagagaaaattggc
cagtatctttccagcaacagggatcataaagcggttggaagacgaccttttgataagatg
gcaacacttcttgcatacctggggcctccagagcacaaacctgtggcagatacacactgg
tccagtcttaaccttacaagttcgaagttcgaggaatttatgactaggcatcaggtacat
gaaaaagaagagttcaaggctttgaaaacgttaagtattttctaccaagctggaacttcc
aaagctgggaatcctattttttattatgttgcacggaggttcaaaactggtcaaatcaat
ggcgatttgctgatataccacgtcttgctgactttaaagccatattatgcaaagccatat
gaaatcgtagtggaccttacccatactgggcctagcaaccgctttaaaacagactttctc
tccaagtggtttgttgtttttcctggctttgcttatgataatgtctctgcagtctatatc
tacaactgtaactcctgggtcagggagtacaccaaatatcatgagcggctgcttacgggc
ctcaaaggtagcaaaaggctcattttcattgactgccctgggaaactagctgagcacata
gagcatgaacaacagaaactacctgctgctaccttggctttagaagaggacctgaaggta
ttccacaatgctctcaaactagctcacaaagacaccaaagtttctattaaagttggttct
actgctgttcaagtaacctcagcagagcgaacaaaagtcctggggcagtcagtctttcta
aatgatatctattatgcctcggaaattgaagagatctgcctagtggatgagaaccagttc
acgttaaccattgcaaaccagggcacaccgctcaccttcatgcaccaggagtgtgaagcc
attgtccagtctatcattcatatccggacccgatgggagctatcgcagcctgactcgatc
ccccagcacaccaaaattcggccaaaagatgtccctgggacactgctcaatatcgcatta
cttaatttaggcagttcagaccctagtttacggtcagctgcctataatcttctgtgtgcc
ttaacttgtacctttaatttaaaaatcgagggccagttactagagacatcaggtttatgt
atccctgccaacaacaccctctttattgtgtctattagtaagacactggcagccaatgag
ccacacctcacgttagaatttttggaagagtgtatttctggatttagcaaatctagtatt
gaattgaaacacctttgtttggaatacatgactccgtggctgtcaaatctagtgcgtttt
tgtaagcataatgatgatgccaaacgacaaagagttactgctattcttgataagctgata
acaatgaccataaatgagaaacaaatgtatccatctattcaagcaaaaatatgggggagc
cttgggcagattacagatctgcttgatgttgtactagacagtttcatcaaaaccagtgca
acaggtggcttgggatcaataaaagctgaggtcatggcagatactgctgtagctttggct
tctggaaatgtgaaattggtttcaagcaaggttattggaaggatgtgcaagataattgac
aagacatgcttatctccaactcctactttagaacaacatcttatgtgggatgatattgct
attctagcacgctacatgctaatgctgtccttcaataattcacttgatgtggcggctcat
ctcccctacctcttccacgttgttacatttttagtagccacaggtccactctctcttaga
gcttccacacatggattggtcattaacatcattcactctctgtgtacctgttcacagctt
cattttagtgaagagaccaagcaagttttgagactcagcctaacagagttctcattaccc
aaattttacttgctgtttggcattagcaaagtcaagtcagcagctgtcattgccttccgc
tccagttaccgggacaggtcattctctcctggctcctatgaaagggaaacttttgctttg
acatccttggaaacagtcacagaagctttgttagagatcatggaggcatgtatgagagat
attccaacatgcaagtggctggaccagtggacagaactagctcaaagatttgcattccag
tataatccatccctgcaaccaagagcccttgttgtctttggctgtattagcaaacgagtg
tctcacgggcagataaagcagattatccgtattcttagcaaggctcttgagagttgctta
aaaggacctgatacttacaacagtcaagttctgatagaagctacagtaatagcactaacc
aaattacagccacttcttaataaggactcccctctgcacaaagccctcttttgggtagct
gtggctgtgctgcagcttgatgaagtcaacttgtattcagcaggcactgcacttcttgaa
caaaatctgcacaccttagatagtctccggatattcaatgacaagagtccggaggaagta
tttatggcaatccggaatcctctggaatggcactgcaagcaaatggatcattttgttgga
ctcaatttcaactctaattttaactttgccctggttggacacctcttaaaagggtacagg
catccctcacctgccattgttgcaagaacagtcagaattttgcatacactactaactctg
gttaacaaacatagaaattgtgacaaatttgaggtgaatacacagagcgtggcttactta
gcagctttactcacagtgtctgaagaggttcgaagtcgctgcagcctaaaacatagaaag
tcacttcttcttactgatatttcaatggaaaatgttcctatggatacatatcccattcat
catggtgaccccagctataggactctgaaggagaatcagccatggtcctctcccaaaggt
tctgaggggtaccttgcagcttcctatccaactgtgggccagaccagtcctcgagccagg
aaatccatgagcttggacatgggacagccttctcaggccaacactaagaagttgcttgga
acaaggaaaagttttgatcacttgatatcagacacaaaggcccctaaaaggcaagaaatg
gaatcagggatcacaacaccacccaaaatgaggagagtagcagagactgattatgaaatg
gaaactcaaaggatttcttcatcacaacagcacccacatttgcgtaaagtttcagtgtct
gaatcaaatgttctcttggatgaggaagtacttactgatccgaagatccaagctcttctt
cttactgttctagctacactggtgaaatataccacggatgaatttgatcaacgaattctt
tatgaatacttagcagaggccagtgttgtgttccccaaagtttttcctgttgtgcacaat
ttgttggactctaagatcaataccctgttgtcattgtgccaagatccaaatttgttaaat
ccgatccatggaattgtgcagagtgtggtgtaccatgaagaatcaccaccacaataccaa
acgtcttacctgcaaagttttggttttaatggcttgtggcggtttgcaggacccttttca
aagcaaacacaaatcccagactatgctgagcttattgttaagtttcttgatgccttgatt
gacacgtacttgcctggaattgatgaagaaaccagtgaggagtccctcctgacacccaca
tctccttaccctcctgcactgcagagccagcttagtatcactgccaaccttaacctctct
aattccatgacctcacttgcaacttcccagcattccccaggaattgacaaggagaatgtt
gaactctcccctaccactggccactgtaacagtggacgaactcgccacggatccgcaagc
caagtgcagaagcaaagaagtgctggcagtttcaaacgtaatagcattaagaagatcgtg
tga
DBGET
integrated database retrieval system
