KEGG   Galeopterus variegatus (Sunda flying lemur): 103605698
Entry
103605698         CDS       T08727                                 
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase-like
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
gvr  Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr01521  EGFR tyrosine kinase inhibitor resistance
gvr01522  Endocrine resistance
gvr01524  Platinum drug resistance
gvr04010  MAPK signaling pathway
gvr04012  ErbB signaling pathway
gvr04014  Ras signaling pathway
gvr04015  Rap1 signaling pathway
gvr04022  cGMP-PKG signaling pathway
gvr04024  cAMP signaling pathway
gvr04062  Chemokine signaling pathway
gvr04066  HIF-1 signaling pathway
gvr04068  FoxO signaling pathway
gvr04071  Sphingolipid signaling pathway
gvr04072  Phospholipase D signaling pathway
gvr04140  Autophagy - animal
gvr04150  mTOR signaling pathway
gvr04151  PI3K-Akt signaling pathway
gvr04152  AMPK signaling pathway
gvr04210  Apoptosis
gvr04211  Longevity regulating pathway
gvr04213  Longevity regulating pathway - multiple species
gvr04218  Cellular senescence
gvr04261  Adrenergic signaling in cardiomyocytes
gvr04370  VEGF signaling pathway
gvr04371  Apelin signaling pathway
gvr04380  Osteoclast differentiation
gvr04510  Focal adhesion
gvr04550  Signaling pathways regulating pluripotency of stem cells
gvr04611  Platelet activation
gvr04613  Neutrophil extracellular trap formation
gvr04620  Toll-like receptor signaling pathway
gvr04625  C-type lectin receptor signaling pathway
gvr04630  JAK-STAT signaling pathway
gvr04660  T cell receptor signaling pathway
gvr04662  B cell receptor signaling pathway
gvr04664  Fc epsilon RI signaling pathway
gvr04666  Fc gamma R-mediated phagocytosis
gvr04668  TNF signaling pathway
gvr04722  Neurotrophin signaling pathway
gvr04725  Cholinergic synapse
gvr04728  Dopaminergic synapse
gvr04810  Regulation of actin cytoskeleton
gvr04910  Insulin signaling pathway
gvr04914  Progesterone-mediated oocyte maturation
gvr04915  Estrogen signaling pathway
gvr04917  Prolactin signaling pathway
gvr04919  Thyroid hormone signaling pathway
gvr04920  Adipocytokine signaling pathway
gvr04922  Glucagon signaling pathway
gvr04923  Regulation of lipolysis in adipocytes
gvr04926  Relaxin signaling pathway
gvr04929  GnRH secretion
gvr04931  Insulin resistance
gvr04932  Non-alcoholic fatty liver disease
gvr04933  AGE-RAGE signaling pathway in diabetic complications
gvr04935  Growth hormone synthesis, secretion and action
gvr04936  Alcoholic liver disease
gvr04973  Carbohydrate digestion and absorption
gvr05010  Alzheimer disease
gvr05017  Spinocerebellar ataxia
gvr05132  Salmonella infection
gvr05135  Yersinia infection
gvr05142  Chagas disease
gvr05145  Toxoplasmosis
gvr05152  Tuberculosis
gvr05160  Hepatitis C
gvr05161  Hepatitis B
gvr05162  Measles
gvr05163  Human cytomegalovirus infection
gvr05164  Influenza A
gvr05165  Human papillomavirus infection
gvr05166  Human T-cell leukemia virus 1 infection
gvr05167  Kaposi sarcoma-associated herpesvirus infection
gvr05168  Herpes simplex virus 1 infection
gvr05169  Epstein-Barr virus infection
gvr05170  Human immunodeficiency virus 1 infection
gvr05200  Pathways in cancer
gvr05205  Proteoglycans in cancer
gvr05207  Chemical carcinogenesis - receptor activation
gvr05208  Chemical carcinogenesis - reactive oxygen species
gvr05210  Colorectal cancer
gvr05211  Renal cell carcinoma
gvr05212  Pancreatic cancer
gvr05213  Endometrial cancer
gvr05214  Glioma
gvr05215  Prostate cancer
gvr05218  Melanoma
gvr05220  Chronic myeloid leukemia
gvr05221  Acute myeloid leukemia
gvr05222  Small cell lung cancer
gvr05223  Non-small cell lung cancer
gvr05224  Breast cancer
gvr05225  Hepatocellular carcinoma
gvr05226  Gastric cancer
gvr05230  Central carbon metabolism in cancer
gvr05231  Choline metabolism in cancer
gvr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
gvr05415  Diabetic cardiomyopathy
gvr05417  Lipid and atherosclerosis
gvr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:gvr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103605698
   04012 ErbB signaling pathway
    103605698
   04014 Ras signaling pathway
    103605698
   04015 Rap1 signaling pathway
    103605698
   04370 VEGF signaling pathway
    103605698
   04371 Apelin signaling pathway
    103605698
   04630 JAK-STAT signaling pathway
    103605698
   04668 TNF signaling pathway
    103605698
   04066 HIF-1 signaling pathway
    103605698
   04068 FoxO signaling pathway
    103605698
   04072 Phospholipase D signaling pathway
    103605698
   04071 Sphingolipid signaling pathway
    103605698
   04024 cAMP signaling pathway
    103605698
   04022 cGMP-PKG signaling pathway
    103605698
   04151 PI3K-Akt signaling pathway
    103605698
   04152 AMPK signaling pathway
    103605698
   04150 mTOR signaling pathway
    103605698
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103605698
  09143 Cell growth and death
   04210 Apoptosis
    103605698
   04218 Cellular senescence
    103605698
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103605698
   04550 Signaling pathways regulating pluripotency of stem cells
    103605698
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103605698
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103605698
   04613 Neutrophil extracellular trap formation
    103605698
   04620 Toll-like receptor signaling pathway
    103605698
   04625 C-type lectin receptor signaling pathway
    103605698
   04660 T cell receptor signaling pathway
    103605698
   04662 B cell receptor signaling pathway
    103605698
   04664 Fc epsilon RI signaling pathway
    103605698
   04666 Fc gamma R-mediated phagocytosis
    103605698
   04062 Chemokine signaling pathway
    103605698
  09152 Endocrine system
   04910 Insulin signaling pathway
    103605698
   04922 Glucagon signaling pathway
    103605698
   04923 Regulation of lipolysis in adipocytes
    103605698
   04920 Adipocytokine signaling pathway
    103605698
   04929 GnRH secretion
    103605698
   04915 Estrogen signaling pathway
    103605698
   04914 Progesterone-mediated oocyte maturation
    103605698
   04917 Prolactin signaling pathway
    103605698
   04926 Relaxin signaling pathway
    103605698
   04935 Growth hormone synthesis, secretion and action
    103605698
   04919 Thyroid hormone signaling pathway
    103605698
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103605698
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    103605698
  09156 Nervous system
   04725 Cholinergic synapse
    103605698
   04728 Dopaminergic synapse
    103605698
   04722 Neurotrophin signaling pathway
    103605698
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103605698
  09149 Aging
   04211 Longevity regulating pathway
    103605698
   04213 Longevity regulating pathway - multiple species
    103605698
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103605698
   05205 Proteoglycans in cancer
    103605698
   05207 Chemical carcinogenesis - receptor activation
    103605698
   05208 Chemical carcinogenesis - reactive oxygen species
    103605698
   05230 Central carbon metabolism in cancer
    103605698
   05231 Choline metabolism in cancer
    103605698
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103605698
  09162 Cancer: specific types
   05210 Colorectal cancer
    103605698
   05212 Pancreatic cancer
    103605698
   05225 Hepatocellular carcinoma
    103605698
   05226 Gastric cancer
    103605698
   05214 Glioma
    103605698
   05221 Acute myeloid leukemia
    103605698
   05220 Chronic myeloid leukemia
    103605698
   05218 Melanoma
    103605698
   05211 Renal cell carcinoma
    103605698
   05215 Prostate cancer
    103605698
   05213 Endometrial cancer
    103605698
   05224 Breast cancer
    103605698
   05222 Small cell lung cancer
    103605698
   05223 Non-small cell lung cancer
    103605698
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103605698
   05170 Human immunodeficiency virus 1 infection
    103605698
   05161 Hepatitis B
    103605698
   05160 Hepatitis C
    103605698
   05164 Influenza A
    103605698
   05162 Measles
    103605698
   05168 Herpes simplex virus 1 infection
    103605698
   05163 Human cytomegalovirus infection
    103605698
   05167 Kaposi sarcoma-associated herpesvirus infection
    103605698
   05169 Epstein-Barr virus infection
    103605698
   05165 Human papillomavirus infection
    103605698
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103605698
   05135 Yersinia infection
    103605698
   05152 Tuberculosis
    103605698
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103605698
   05142 Chagas disease
    103605698
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103605698
   05017 Spinocerebellar ataxia
    103605698
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103605698
   05418 Fluid shear stress and atherosclerosis
    103605698
   05415 Diabetic cardiomyopathy
    103605698
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103605698
   04932 Non-alcoholic fatty liver disease
    103605698
   04931 Insulin resistance
    103605698
   04933 AGE-RAGE signaling pathway in diabetic complications
    103605698
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103605698
   01524 Platinum drug resistance
    103605698
   01522 Endocrine resistance
    103605698
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:gvr01001]
    103605698
Enzymes [BR:gvr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     103605698
Protein kinases [BR:gvr01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   103605698
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Seadorna_VP7 BA_2335-like
Other DBs
NCBI-GeneID: 103605698
NCBI-ProteinID: XP_008588546
LinkDB
Position
Unknown
AA seq 361 aa
MEKDDWCKVCTSAIVQSMRGLVWSPVEQGYESELCNFRRHSQFPLGNLEKISQLLSKSAQ
CPLRVHYLSSQYADERCFMFVLISPTKSVIITILSLLFTLQLFFHLSRERVFSEDRTRFY
GAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPE
YLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSS
DAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKSQGSTRLSVDRAGR
LHVQRPVAAAAQARVHVLTGAGHMRRRRCLLPTDDEDGMDCADSERRPHFPQFSYSASGR
E
NT seq 1086 nt   +upstreamnt  +downstreamnt
atggagaaggatgactggtgcaaggtatgcacctcagctatagtacagagcatgcgaggg
ttggtttggagcccagtagaacaaggttatgagagtgagctctgcaactttcgtcgacac
tcgcagtttccccttggaaacctggaaaagataagccagctgctgtctaagagtgctcag
tgtccactgagagtacactatctatcatcacaatatgctgatgagaggtgttttatgttt
gtgttaatttcccccactaaatcagtaattattacaatcctgtccctgctgtttaccctg
cagctgtttttccatttgtcgagagagcgggtgttctctgaggaccgcacacgtttctat
ggtgcagaaattgtctctgccttggactatctacattccggaaagattgtgtaccgtgat
ctcaagttggagaatttgatgctggacaaagatggacacataaaaattacagattttggg
ctttgcaaagaagggatcacagatgctgccaccatgaagacattctgtggtacacccgag
tatctggcaccagaggtattagaagataatgactatggccgagcagtggactggtggggc
ctgggggttgtcatgtatgaaatgatgtgtgggaggttacctttctacaaccaggatcac
gagaagctttttgaactgatactgatggaagacattaaatttcctcgaacactctcttca
gatgcaaaatcattgctttcagggctcttgataaaggatccaaataaacgccttggtgga
ggaccagatgatgcaaaagaaattatgagacacagtttcttttctggagtaaactggcaa
gatgtatatgataaaaagtcgcagggcagcacgcgcttgagcgtagacagagcaggacgg
cttcacgtgcagcgtcctgtggccgcggcggcacaggcgcgggtgcatgtgttgaccggg
gcgggacacatgagaagacgccgctgtctcctgcccacagatgacgaggacggcatggac
tgcgcggacagcgagagacggcctcacttcccgcagttttcctactccgccagcggccgg
gaataa

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