Galeopterus variegatus (Sunda flying lemur): 103608308
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Entry
103608308 CDS
T08727
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr00270
Cysteine and methionine metabolism
gvr00480
Glutathione metabolism
gvr01100
Metabolic pathways
gvr01240
Biosynthesis of cofactors
gvr04216
Ferroptosis
Module
gvr_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
103608308 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
103608308 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
103608308 (GCLC)
Enzymes [BR:
gvr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
103608308 (GCLC)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
103608308
NCBI-ProteinID:
XP_008591008
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All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETQRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
EKKKVQLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSILEENQALCTITSFPRLGCPGFTLPEYKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSNCGEKYNDINLTIDKEIYKQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
KGMFYFRKDICKGGNAVVDGRGKAQNSTELTAEEYTLMSIDTIISGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS
LILKCNQIANELCECPELLGSAFRKVKYSGSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggttgctgtcccagggttcgccgctgagttgggaggagacccagcgccacgcagac
cacgtgcggcggcacgggatcctccagttcctgcatatataccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggagacgaggtggaatacatgttggtatcttttgatcat
gaaaagaaaaaagttcaattggtcctgtctggagaggaagttcttgaaactctacaagag
aagggggaaaggacaaatccaaaccatcctaccctgtggagaccagagtatgggagttac
atgattgaagggacacctggacagccctacggaggaacaatgtccgagttcaacacagtt
gaggacaacatgagaaaacgccggaaggaggctacctctatattagaagaaaatcaggct
ctttgcacaataacttcatttcccagattaggctgtcccgggttcacactgcctgagtac
aaacctaacccggttgaaggaggagcttccaagtctctcttctttccagatgaagcgata
aacaagcacccccgcttcagcaccctaacaagaaatatccgacataggagaggagaaaaa
gttgtcatcaatgtaccaatatttaaggacaagaatacaccatctccgtttatagaaaca
tttcctgaggatgatgaggcagcaaaggcttccaaaccggatcatatttacatggatgcc
atgggatttgggatgggcaattgctgtcttcaggtgacattccaagcctgcagcatatct
gaggccagatatctttatgatcagttggccacgatctgtccaattgtcatggctttgagt
gctgcatctcctttttaccgaggctatgtgtcagatattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggaaagaggactggagcctctgaagaacaat
aactataggattagtaaatcccgatatgattcaatagacagctacttatctaattgtggt
gagaaatataatgacatcaacttgacgatagataaagaaatctacaaacaactcttacaa
gaaggcattgatcatctcctggcccagcatgttgctcatctctttattagagacccactg
actctatttgaagaaaaaatacacctggatgacgccaatgagtctgaccattttgagaat
attcagtccacaaattggcagacaatgagatttaagccccctcctccaaactcagatatt
ggatggagagtagaatttcgacccatggaggtccagttaacagactttgagaactctgcc
tatgtggtgtttgtggtgctgctcaccagagtcatcctttcgtacaaattggattttctc
attccactgtcaaaggttgatgaaaacatgaaagtagcacagaaacgagatgctgtcttg
aagggaatgttttatttcaggaaagatatttgcaaaggtggtaatgcagtggtagatggg
cgtggcaaggcccagaatagcacagagctcactgcagaggagtacaccctcatgagcata
gacaccatcatcagtgggaaggaaggtgtgtttcctggactgatcccgattctgaactct
taccttgaaaacatggaagtggatgtggacaccagatgtagtattctgaactacttaaag
ctgattaagaagagagcatctggagaactaatgacagttgccaggtggatgagggagttt
atcgcaaaccatcctgactacaaacaagatagtgtaataactgatgaaatgaactatagc
cttattttgaagtgtaaccaaattgcaaatgaattatgtgaatgcccagagttacttgga
tcagcatttaggaaagtaaaatatagtggaagtaaaactgactcttcaaactag
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