Halotalea alkalilenta: A5892_08735
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Entry
A5892_08735 CDS
T04333
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
haa
Halotalea alkalilenta
Pathway
haa00300
Lysine biosynthesis
haa00550
Peptidoglycan biosynthesis
haa01100
Metabolic pathways
haa01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
haa00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
A5892_08735
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
A5892_08735
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
A5892_08735
Enzymes [BR:
haa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
A5892_08735
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
ANF57537
UniProt:
A0A172YEB1
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All DBs
Position
1987384..1988772
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AA seq
462 aa
AA seq
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MIATLARASAATGAEFEGDDRPFSRPITDSRQVGEGDLFFAMRGETMDGHRFVADALAAG
AAAVVVEHDLAAELPEAAGRQLIVADTRLALGLLGGHARLAWGGPLVAVTGNSGKTTVKE
LVKSILEVAAGDDQRVLATQGNLNTYVGVPQTLCRLRDHHRFAVVELGANHVGEIAWTAP
LARPQVAVITNVTGAHAGEFGGLARIAQAKAEVLLGLAPNGVAVLNRDDRFYPLWRQMAL
LRGEPSMLVDFGLDPQARIGAERIVHDDDGRHRFVLRLDGQRVGEVALGLVGLHNVRNAL
AASAAADALGVEPAAIIEGLERVGDVGGRMTLRHGREGRRLLDDSYNANPGAFRAALETL
ALQPAPRWCLMGAMAELGAESAVRHAELGSYAKHLGIDALIAYGADAAPAAEAFGGACFD
DWQTFVDYVEAQLPAGASVLIKGSRSMRMERLVDRLSAADAK
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atgatcgctacccttgcccgggcctcggctgcgaccggggccgagttcgagggcgatgac
cggcccttctcgcgcccgatcaccgatagtcgccaggtcggcgaaggggatcttttcttc
gccatgcgcggggagacgatggatggccaccgcttcgtcgccgacgcgctcgccgcgggg
gccgcggcggtagtggtcgagcacgacctcgccgccgagctgcccgaggcagcggggcgc
cagctgatcgtcgccgatacccggctcgcgctcggcctgctcggcggccacgcgcggctg
gcctggggcgggccgttggtggcggtcaccggcaatagcggcaagaccacggtcaaggag
ctggtcaagtcgatcctcgaggtcgctgcgggcgacgaccagcgagtgctcgccacccag
ggcaatctcaatacctacgtcggcgtaccgcagacgctctgtcggctgcgcgaccatcac
cgcttcgcagtggtcgagctcggcgccaaccatgtcggtgagatcgcctggacggcgccg
ctggctcgcccccaggtcgcggtgatcaccaacgtcaccggcgcgcacgccggcgagttc
ggcgggcttgcccgcatcgcccaggccaaggccgaggtgctgctcggtctcgccccgaac
ggggtcgcggtgctcaaccgcgacgaccgcttctacccgctttggcgtcaaatggcgctt
ttgcgtggtgagccgagtatgctcgtggacttcgggctcgacccgcaggcgcggatcggc
gctgagcgcatcgtccacgacgatgatggtcgccaccgcttcgtactgcgactcgatggg
cagcgggttggcgaagtcgcgcttggactggtgggactgcacaacgtacgcaatgcgctc
gccgcgagcgccgccgcggatgcgctgggcgtggagccggcggcgatcatcgaagggctc
gaacgggtgggcgacgtcggcgggcggatgacgcttcgccatgggcgcgaggggcggcgg
ctgctcgacgatagctacaacgccaacccaggggcctttcgtgccgcactcgagacactg
gcgctgcagccagcgccgcgttggtgtctgatgggggcgatggccgagctcggcgctgaa
tcggccgtgcgccacgccgagctcggcagctacgccaagcacctcggtatcgatgcgctc
atcgcctatggcgccgacgccgcaccagcggccgaggccttcggcggtgcttgcttcgat
gattggcagacgttcgtcgactacgtcgaggcccagctacccgcgggcgcctcggtattg
atcaagggatcgcgcagtatgcgcatggagcggctggtagatcgtctctccgccgccgac
gcgaagtga
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