Halomonas sp. DN3: NKF27_12085
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Entry
NKF27_12085 CDS
T10930
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
hadn Halomonas sp. DN3
Pathway
hadn00790
Folate biosynthesis
hadn01100
Metabolic pathways
hadn01240
Biosynthesis of cofactors
Module
hadn_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
hadn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
NKF27_12085 (folC)
Enzymes [BR:
hadn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
NKF27_12085 (folC)
6.3.2.17 tetrahydrofolate synthase
NKF27_12085 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
USZ48261
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All DBs
Position
complement(2782716..2784089)
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AA seq
457 aa
AA seq
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MDNDGLPTTLDSWLARLEAAHPVGIDLGLERVACVAQRLGLTERPIARRVITVAGTNGKG
STVAMLEALGRAHGLSTAAYTSPHLVRYNERLRLDASEASDEVLIEGFVAVEQARLAPSP
VSLTYFEVGTLAALWTIARRQPELAVLEVGLGGRLDAVNVVDPDVAVVTTVAQDHAAFLG
NDIAIIGREKAGIMRTGRPAVLGSPDLPSSVADHARSLGAPIFALGEAFAHSGSHAGSQA
AHCAGPDGEQGGWSWRGSDAQGQPVGLERLSDPGLPMDNAAAALQALWLALGELDPDACR
QALAEVRLPGRMQWRGNWCLDVGHNPHAANYLAGRLAERREVQRDVQGRTLCLIGMLEDK
DAEGVIAALSPVVDAWLPVTLEGDRGRSAADLAARIEHQGGTILHHADSVDDGADWLESC
VEPADRVLVTGSFFTVAAILARWSRQSSGGGVIEGAT
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atggacaacgacggtctgcccaccacgctggatagctggctcgcccgactcgaggccgcc
caccccgtcggcatcgatctgggcctcgagcgggtcgcctgtgtggcacagcgtctcggt
ctgaccgagcggccgattgcacgccgggtgatcaccgtcgccggcaccaacggcaagggg
tccacggtggccatgctcgaggcgctgggacgggcccatgggttgtccacggcggcctac
acctcgccccatctggtgcgttacaacgagcgccttcggctggacgccagcgaggccagc
gacgaggtgctgatcgaaggcttcgtcgcggtggagcaggccaggctcgcgccatccccg
gtcagcctcacctacttcgaggtcggtaccctggcggcgctgtggaccatcgccaggcgc
cagcccgagctggcggtgctggaggtcggcctcggtggtcgcctggatgcggtcaatgtg
gtggatccggatgtggccgtggtgaccaccgtggctcaggaccacgccgccttcctgggc
aacgatatagcgatcatcggccgcgagaaagccgggatcatgcgtaccgggcgcccggcg
gtgcttggcagtcctgacctgccctcgagcgttgccgaccatgcccgttcgctgggtgcg
ccgatctttgcgctcggcgaggccttcgcccattcgggcagccatgcaggctctcaagca
gcacattgtgcaggacctgatggcgaacagggcggctggtcgtggcgcggcagcgacgcg
caaggccagccggtcggcctggaacgactaagcgatcccgggctgccgatggataacgcc
gctgctgcgctgcaggcactgtggctggcccttggtgaactcgatccagacgcctgtcgc
caggcactggccgaggtgcgtcttcccgggcggatgcagtggcgcggtaactggtgcctt
gacgtgggtcacaaccctcacgccgccaactacctggccgggcgactggccgaacggcgt
gaagtgcaaagggacgtccaggggcggaccctgtgtctgatcggcatgctcgaggacaag
gacgccgagggggtcatcgccgcgctgtcgccggtggtggacgcctggctgccggtgacg
ctcgagggcgatcgcggacgtagcgcagccgacctggcggcacgcatcgaacatcaaggt
ggcaccatccttcaccacgccgatagcgtcgatgacggcgccgactggctcgaatcgtgc
gtcgagccggcagatcgtgtactggtgacgggatccttcttcaccgtggctgccatactg
gcgagatggagccgccagtccagtggcggtggcgtcatcgagggagcgacatga
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