Haemophilus aegyptius: NCTC8502_01258
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Entry
NCTC8502_01258 CDS
T06550
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
haeg
Haemophilus aegyptius
Pathway
haeg00300
Lysine biosynthesis
haeg00550
Peptidoglycan biosynthesis
haeg01100
Metabolic pathways
haeg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
haeg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NCTC8502_01258 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NCTC8502_01258 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NCTC8502_01258 (murF)
Enzymes [BR:
haeg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NCTC8502_01258 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Beta-prop_FAM234A_B
Motif
Other DBs
NCBI-ProteinID:
SQH37443
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All DBs
Position
1:1179024..1180397
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AA seq
457 aa
AA seq
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MIKLSTVQLAQILQAKLIGDENVQVEEINTDTRKSVSNSLFFALKGEKFDAHQYLDQAVS
QGALALVVQQENSSILVPQLVVKDTRIALGELAKWLREKINPRTVAMTGSSGKTTVKEMT
ASILQHTAADSEAVLFTNGNFNNDIGVPLTLLRLTEKHRFAVIELGANHQNEINYTTKLV
QPNAALINNIAPAHLEGFGSLAGVVQAKGEIYRGLTKNGVAIINAEHNHLDIWQKEISNH
AIQYFNGKDYSVKNVQGNEQGSTFTLVSPQGEIDISLPYLGEHNVKNALAATALAMNVGA
TLADVKAGLEQRSQVKGRLLPIQVTPNLLLLDDTYNANKDSLCAAIDVLKSYDAFLILCV
ADMKELGENSLAIHREVGQYVNLVNLDLVCSYGNESAVISEAVLGKHFTDKTEMVDFLVP
LIENQLQQNKKVVVLGKGSRSMKMEDVIYSLKDKIKC
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgattaaactctctactgtacaacttgcacagattcttcaagctaaattaattggcgat
gaaaatgtgcaagttgaagaaattaatacggatactcgaaaaagcgtatcaaatagctta
ttttttgctttaaaaggcgaaaaatttgatgctcaccaatatcttgatcaagcggtgtca
cagggtgcgcttgcgcttgttgttcagcaagaaaactcgtctattttagttcctcaactt
gtggttaaggatacccgtattgccttgggtgaacttgcaaaatggttacgtgagaaaatt
aatccacgtactgtggcgatgaccggctcttctggtaaaaccacggtaaaagaaatgacg
gcaagtattttgcaacataccgcagcagattcagaagcggtactttttaccaatggtaac
ttcaataacgatataggtgtgcctttaactctacttcgcttaacagaaaaacatcgtttt
gctgtgattgaacttggtgcaaatcatcaaaatgaaatcaattacaccacaaaattagtt
caacctaatgccgcattgattaataatattgcgcccgcacatttagaggggtttggttct
ttagcgggagttgttcaagcaaaaggcgagatttatcgaggtttaacaaaaaatggtgtg
gcgattatcaatgctgaacataatcacttagatatttggcaaaaagaaattagtaatcac
gccattcaatatttcaacggtaaggactattccgtcaaaaatgttcaaggtaacgaacaa
ggttcaacctttacgttagtttctccgcaaggcgaaattgatattagtttaccttatctt
ggagagcataatgtaaaaaatgctttagctgctaccgcactagcgatgaatgttggtgct
acgcttgccgatgtcaaagctggattagaacaacgttcacaagtgaaagggcgtttactt
cctattcaagtcacgcctaatttattgttattagatgatacttataacgcaaataaagat
tctctctgtgcggctattgatgtcctaaaaagttatgatgctttccttattctatgtgtc
gcagatatgaaagaattgggcgaaaattctctcgctattcatcgtgaagttggacaatat
gttaatttggtaaatttagatttagtttgttcttatggcaatgaaagtgcggttatttct
gaggctgttttgggtaagcattttacggataaaactgaaatggtggatttcttagttcca
cttattgaaaaccaattacaacaaaataaaaaagttgtggtgctaggaaaaggttcacgc
tcaatgaaaatggaagatgtgatctattcattaaaggataaaattaaatgttag
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