Halomonas sp. GFAJ-1: BB497_06705
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Entry
BB497_06705 CDS
T05375
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
hag
Halomonas sp. GFAJ-1
Pathway
hag00230
Purine metabolism
hag01100
Metabolic pathways
hag01110
Biosynthesis of secondary metabolites
Module
hag_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
hag00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
BB497_06705
Enzymes [BR:
hag01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
BB497_06705
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AAA_16
Motif
Other DBs
NCBI-ProteinID:
AVI62418
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Position
1469456..1473376
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AA seq
1306 aa
AA seq
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MLELRGAPALSAFRHERLLTVLRERVPEVEALSAHYVHFIDHHEELDNATQERLAQLLDY
GSHESQDAPENAQRFLVVPRLGTQSPWSSKATDIAHNCGLGQISRIERGIDYRVGLRGDV
SADTLQAVAALLHDRMIETVLDDAADAAKLFAHHAPAPLGSVDILDGGRDALATANRELG
LALAEDEIDYLVAAFVELGRNPSDVELMMFAQANSEHCRHKIFNADWVIDGEAQPYSLFK
MIKNTFASSPDNVLSAYSDNAAVIKGSYGGRFFPTPLTGAEGERASYDAHQEPIHILMKV
ETHNHPTAIAPFPGAATGSGGEIRDEGATGIGGKPKAGLSGFTVSNLRIPEFVQPWEAFD
YGKPERMQSALQIMLDGPIGGAAFNNEFGRPNLTGYFRTYEQDTLSEGGIERRGFHKPIM
LAGGYGNIRAQHVQKGEIPVGGKLIVMGGPAMLIGLGGGAASSMASGVSSADLDFASVQR
ENPEIERRAQEVIDRCWALGLQNPIRFIHDVGAGGLSNALPELVKDGNRGGLFDLRAVPN
AEPGMSPLEIWCNEAQERYVLAVAPEDLATFDALCKRERCPYAVVGEALEHHHLEVRDGH
FDTKPVDLPMSVLFGKAPKMTRTFERQTPELSGVMLDNLDLREALDRVLRLPAVASKSFL
ITIGDRSITGQVARDQMVGPWQVPVADVAVTTASFDTHAGEAMAMGERPPVALINPAASA
RLAVAEAITNLAAAPIAKLSDIKLSANWMSAADHPGENQALFEAVHAVGMELCPALGIAI
PVGKDSMSMRTAWQDDADEKSITSPLSLVVTGFAPVTDALATLTPQINVEQEESDLILID
LGNGQNRLGGSALAQVYGQVGNECPDVDDPEDLKAFFEVIQGLNRDGKLLAYHDRSDGGL
LVTLLEMAFAAHAGLEIKLDWLIDEPVEAFNALFSEELGAVIQVNRADTEEVLTQFAIAG
IETCGVIARPRYDDQVRVTLFEEPLLETTRQLTQRTWTETSYRMQALRDNPECAKNEFDN
LLDARDPGLSAAPSFDINDDISAPFINTTKPAVAVLREQGVNGQVEMGWAFHKAGFDAVD
VHMSDILEGRVSLDEFKGLVACGGFSYGDVLGAGGGWAKSVLFNERAREQFAAFFTRDDS
FSLGVCNGCQMLSQLKTLIPGAENWPAFVRNESEQFEARVAMVRVEKSPSILLAGMEGSK
LPIAVAHGEGRAEFRDTAHLRTMQSSSQIALRYIDNYGQVTTRYPANPNGSPSGITGLTT
PDGRVTIMMPHPERVTRAVTNSWRPAEWTEDGAWLRLFRNARVWLG
NT seq
3921 nt
NT seq
+upstream
nt +downstream
nt
atgctcgaactgcgaggcgcacccgccctttctgccttccgccatgaacggctgttaacg
gtgttgcgtgaacgtgttccggaggtggaggcgctatccgcccattacgtccacttcatt
gatcaccacgaagagctcgataacgccactcaagagcgtttagctcagctgctcgactac
ggtagccacgaaagccaagacgccccggaaaacgcccagcgttttctggtggtgccgcgc
ttaggcactcagtctccctggtcctctaaagcaaccgatatcgcccataactgtgggctg
ggtcaaattagccgcattgagcgaggtattgattaccgagtagggctacgcggagacgtc
agcgctgacaccctgcaggcagtcgccgcactgctacatgaccgcatgatagaaaccgtg
ctggacgatgccgccgacgccgccaaactgtttgcccatcacgcgccagccccccttggc
agtgtggatattttagacggtggccgcgacgccttagcaacggctaaccgcgagcttggc
ctggccctggcagaagatgaaattgactacttagtggctgcgtttgttgagcttggccgc
aacccaagcgatgtcgagctgatgatgtttgcccaggcaaactctgagcactgccgccat
aaaatcttcaacgcggactgggtaattgatggtgaagcgcagccctattcgctgtttaag
atgattaagaatacctttgcgtcctcgccggataacgtgctttccgcctacagcgacaac
gcggcggtgattaagggcagctacggtggacgcttcttccccacgccgctaacgggtgcc
gagggcgagcgcgctagctacgatgctcaccaagagccgatccacattctgatgaaggtg
gaaacccacaaccaccccacggcgattgcgccatttccaggggcagcgacaggctcaggt
ggtgaaattcgtgacgaaggcgccaccggcatcggcggtaagcccaaagcgggtctctcg
ggctttacggtttctaacctgcgtattcccgaattcgtgcagccttgggaagcctttgat
tacggcaagcccgagcgtatgcagtcggcgttgcaaattatgctggatggcccgatcggt
ggcgcagcgtttaataacgagtttggccgccccaacctaaccggctacttccgcacctac
gagcaggatacgctgagtgaaggtggcattgagcgcagggggttccacaagccgatcatg
ctggcgggtggctacggtaatattcgcgcgcagcacgtgcaaaagggcgaaattcccgtt
ggcggtaagctgattgtcatgggtggccctgccatgctgattggtttgggcggcggtgcg
gcgtccagcatggcatcaggtgtttcaagtgccgatttggactttgcctcggttcagcgg
gaaaacccggagatcgagcgtcgcgctcaagaggtcatcgaccgctgttgggcgttaggt
cttcaaaaccccattcgctttattcacgacgtaggtgcaggggggctttccaacgcgctg
ccagaactcgtcaaagatggtaaccgcggcggtctgtttgacctgcgcgcggtgcccaac
gctgaacccggcatgagcccgctggaaatttggtgtaacgaagcccaggagcgctatgta
ctggcggtggcgccggaagatttagctactttcgatgcgctgtgtaagcgcgagcgctgc
ccctacgcggtagtgggcgaggctcttgagcatcatcacctagaagtgcgcgacggtcat
tttgacaccaaacccgtcgatctaccgatgagcgtgctgtttggcaaagcccccaagatg
acccgcacatttgagcgtcaaacgcctgagctttccggtgtgatgctcgacaacctggac
ctacgtgaggcgctggaccgggtgctgcgtttgcctgcggtggcctctaaaagcttcttg
atcaccattggcgaccgctccattaccggccaagtggcccgtgaccagatggttggcccg
tggcaggtgccggtggctgatgttgctgttactaccgcaagctttgacacccatgccggt
gaagcgatggccatgggcgagcgcccaccggtcgcgctgattaaccccgccgccagcgcc
cgtttggccgttgccgaagcgattaccaacttagccgccgcgcccattgccaagctatcc
gatattaagctctcggctaactggatgagcgccgcggaccaccctggcgaaaaccaagcg
ctatttgaagcggtgcatgcagtgggtatggaactctgcccagcactaggcattgctata
cccgtgggcaaggactccatgtccatgcgcaccgcttggcaggacgatgctgacgagaag
agcatcacttcaccgctctccctggtggtgacggggtttgcgccggtgactgatgcgctt
gccacgctgaccccgcaaatcaatgtggagcaagaagagtctgacttgatcctgattgac
ctggggaatggccaaaaccgcttgggcggctcggcgctggcgcaggtgtatggccaagta
ggcaacgaatgccccgatgtggacgaccccgaagacctaaaagcgtttttcgaggtaatc
cagggcctcaaccgcgacggtaagctgttggcctatcatgatcgcagcgatggcggccta
ctggtcacgttgctggaaatggcctttgctgcccatgcgggccttgaaattaaattggac
tggctgatcgacgagccggtggaagcctttaacgcgctgttctcggaagagctaggcgcg
gtgattcaggtgaaccgggcagacactgaagaagtgctgacccagtttgccatcgcgggt
attgagacctgcggcgttattgcccgcccccgctacgacgaccaagtacgggtcacgctg
tttgaagaaccgttattagaaaccacccgccaactgactcagcgcacttggactgagacc
agctatcgtatgcaggcgctgcgggataatcctgagtgcgcaaagaacgaattcgacaac
ctgcttgacgctcgcgaccctggcttaagtgccgcgcccagcttcgatattaacgacgat
atcagcgcgccgtttattaacaccacaaaacctgcggttgcggtgctgcgcgagcagggg
gttaatggccaggttgagatgggctgggccttccacaaagcgggctttgatgcggtggat
gtgcacatgagcgacatcctggaaggccgtgtttctcttgatgagttcaaagggctcgtc
gcctgtggcggtttctcctacggcgacgtgttgggtgccggcggcggttgggcgaagtcg
gtgctgtttaacgagcgcgcccgggagcagtttgccgcgttcttcacccgcgacgatagc
ttctcgttaggcgtatgtaacggctgtcagatgctttcacagctgaaaacgctgattccc
ggcgctgaaaactggccggcgttcgtacgcaatgagtccgagcagtttgaagcacgggtc
gctatggtgcgggtagaaaagagcccctcgattctattggcgggcatggaaggctccaag
ctgccgattgccgtggcccacggtgaaggccgcgccgagttccgcgataccgcgcacctg
cgcaccatgcagtccagcagccagatcgcgctgcgttatattgataactacggtcaggtg
actacccgctacccggctaaccccaacggctcgccgtcgggcattaccggtttaaccacg
ccagatggccgcgtcaccatcatgatgcctcacccggagcgagtgacccgcgcagttacc
aactcctggcgccccgctgagtggaccgaagatggtgcgtggttgcgcctgttccgtaac
gcccgtgtgtggctgggttaa
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