Halomonas sp. GFAJ-1: BB497_10665
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Entry
BB497_10665 CDS
T05375
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hag
Halomonas sp. GFAJ-1
Pathway
hag00300
Lysine biosynthesis
hag00550
Peptidoglycan biosynthesis
hag01100
Metabolic pathways
hag01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hag00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BB497_10665
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BB497_10665
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BB497_10665
Enzymes [BR:
hag01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BB497_10665
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Lipase_GDSL_2
Dioxygenase_N
DoxX_3
Motif
Other DBs
NCBI-ProteinID:
AVI63120
UniProt:
H0J457
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All DBs
Position
2371826..2373175
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AA seq
449 aa
AA seq
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MSWTLGDVAAALNLLSPSLPELPLTAVVTDTRQIVPGCLFVALKGPRFDGHEFLEQAYAQ
GAAAALVEQEASSALPQLVCADTRLGLGLLARAWRHRYQLPVVAVTGNSGKTTVKEMAAA
LLAPLGEVLATEGNLNNDFGVPLTLLRLTPAHQAAVVELGANHLGEIAWTSQLTAPDVAI
ITNVTGAHVGEFGGMGQIAQAKSEILSGLSANGVAVLNREDRYFAFWAACAAPRRVISYG
WDSHADVYADALSCDPQGRYAFTLVYQGQALGNVCLPLMGKHNVSNALAAAAAALMVGVA
PAKVVSGLSRLPCLPGRLSSVPGLRNATLLDDTYNANPGAVKAALETLASFPAPRWCALG
AMGELGQASETLHAEIGRFAASLGIETLLTYGDAARSASDAFGRGLHFDDHETLVRHIIN
TLPPDTTLLVKGSRSAGMENVIAALRSDK
NT seq
1350 nt
NT seq
+upstream
nt +downstream
nt
gtgagttggacgttgggggatgttgcggcggcactcaatcttttgtcgccatcgttgccc
gagctaccgttaaccgcggtggtgacggatactcgccagattgtgccgggctgcttgttt
gtcgcactcaaagggccacgttttgacggccatgagtttcttgagcaagcgtacgcgcag
ggcgcggcggccgcgttagtagagcaagaggcgagcagcgctttaccgcaattagtgtgt
gctgatacccgcctggggctaggtctgctggcgcgggcatggcgtcatcgctatcagctg
cctgtcgtcgcagtgacgggtaacagtggtaaaacgaccgtcaaagagatggccgctgcg
ctgttagcacctctgggcgaagtgctagcaacagagggcaacttaaataacgattttggt
gtgccgttgacgctactgcggcttactccggctcaccaggcggcagttgtggagcttggg
gcgaaccatctaggtgaaattgcctggaccagccagctaacggcgcctgatgttgccatt
attacgaatgtgaccggagcccatgtaggcgaatttggcggtatgggccagattgcccag
gcgaaaagtgaaattttatcgggcttaagcgccaacggcgtggcagtgctcaatagagaa
gatcgctatttcgctttttgggcagcttgcgctgccccgcgtcgcgttatcagctacggc
tgggacagtcatgcagatgtgtacgccgatgccctttcctgtgacccacaggggcggtat
gctttcacgcttgtttatcaagggcaggcgcttggtaatgtctgtttgccgctgatgggt
aagcacaatgttagcaatgccctagctgccgctgctgcggcacttatggttggcgtggcg
ccagcaaaagtggtgtcgggcctgtcgcgcttgccctgcctgccagggcgcttgagcagt
gtgccgggtttacgtaatgccacactgctagatgacacgtacaacgccaaccctggtgcg
gttaaagcggcattagagacgctggcaagctttcctgctccgcgttggtgtgctctgggg
gcgatgggggagcttgggcaggcatctgaaacactgcatgctgagattggccgctttgct
gcctcgcttggcatcgaaacgctgctgacgtacggtgatgccgcgcgttcagccagtgac
gcctttggtcgcgggctgcattttgacgaccacgagacgcttgtgcgtcatattattaat
acgttgccgcctgacaccacgctgctggtgaaagggtcgcggagcgcgggcatggaaaat
gtcatcgccgcgctgcgttcggataaataa
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