Hahella sp. KA22: ENC22_04540
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Entry
ENC22_04540 CDS
T05793
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hahe
Hahella sp. KA22
Pathway
hahe00300
Lysine biosynthesis
hahe00550
Peptidoglycan biosynthesis
hahe01100
Metabolic pathways
hahe01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hahe00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ENC22_04540
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ENC22_04540
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ENC22_04540
Enzymes [BR:
hahe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ENC22_04540
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF3950
Motif
Other DBs
NCBI-ProteinID:
AZZ90492
UniProt:
A0AAE5XG33
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Position
1021192..1022538
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AA seq
448 aa
AA seq
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MIGDWLTNDIAKAVDGAAEGDNVAFTCVTTDSRADCSGALFVALKGDRFDGHEYVDAAVS
QGAVAILAQRKVAVDVAQIIVPDSLIGLGRLGALNRKRFNGPVAAVTGSAGKTTVKELLA
SILSQRGEVCKTQGNFNNHIGAPLSLLQLTDAHKSAVFELGASAVGEIAYTVALARPQVA
ILNNAAAVHVEGFGDLASIVKAKGEIVCGLPEDGVAVLNKDDANFSAWVEMAGARKVISF
GMDESAMVRAQDVSLELNGSTFRLCAPEGDIDATLPLPGAHNVRNALAAAAAALALGWTL
SEVRDGLASAAPVKGRMNKLLGINGSVILDDTYNASPTSVKAAIDVLARYPGRRIVALGH
MAELGSAAEEAHREVAQYARDSGVEMLLGIGRWAAEYREGFGDASPVVTTHDDIAAWLRE
RLDPNTTVLVKGSRSAAMENVVKQIVEK
NT seq
1347 nt
NT seq
+upstream
nt +downstream
nt
atgatcggagactggttgacaaatgacatagcgaaagcggtcgacggcgcggctgaaggc
gacaacgttgcttttacctgcgtgacgaccgactcccgggcggattgctccggcgctttg
ttcgttgcgctgaaaggcgaccgcttcgatggtcatgaatatgtagacgccgccgtctct
cagggcgctgtcgccatactggcgcaacgcaaagtggcggtggatgtggcgcagattatt
gtccccgacagcctgatcggtctggggcggctgggcgctctgaaccggaagcgctttaac
gggccagtggcggctgtcaccggtagcgcgggtaagaccacggtgaaagagctgctggct
tctatattgtctcagcgcggcgaggtctgtaagacccagggcaacttcaacaatcacatt
ggcgcgccattgagcctgctgcagttgactgacgctcacaaaagcgcggtgtttgagctg
ggggccagtgcagtgggagagatcgcctacacagtggcgcttgcgcgcccgcaagtggcg
attctgaataacgcggcagccgtgcatgtcgaagggtttggggatctggcgagcatcgtt
aaagccaagggcgagattgtctgtggtttacctgaagatggcgtggcggtgctgaacaaa
gatgacgctaacttttccgcatgggtggaaatggcgggggcgcgcaaagttatcagcttt
ggtatggatgagtctgcgatggtgagagcgcaagacgtgagcctggagctgaacggctcc
acgtttcggttatgcgcgccggagggagacattgatgcgacgctgccgttgccgggcgca
cacaacgttcgcaacgcattggccgcggcggccgccgcactggcgttgggatggactttg
agtgaagtgcgcgacgggctcgcgtcggcggctcctgtgaaaggccgcatgaacaagtta
ctgggaattaatgggagtgtcattcttgatgacacatacaatgccagcccaacttcagtg
aaggccgcgattgacgtcctggcccgctatccagggcgtcgaatcgttgcgctggggcac
atggcggaactgggttctgctgcggaggaagcacatagggaggttgctcaatacgccagg
gacagtggcgtagagatgttattgggaataggccgctgggcggcggaatatcgtgaaggc
ttcggggatgcgtccccggttgttactactcatgacgacatcgccgcatggttgcgcgag
cgcctggaccctaacactactgtgttggtgaaaggctcacggagcgcggcgatggaaaat
gttgtgaagcagattgtggagaaatga
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