Halanaeroarchaeum sp. HSR-CO: HSRCO_1057
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Entry
HSRCO_1057 CDS
T09490
Symbol
folC
Name
(GenBank) Folylpolyglutamate synthase and Dihydropteroate synthase
KO
K24102
dihydrofolate synthase / dihydropteroate synthase [EC:
6.3.2.12
2.5.1.15
]
Organism
hahs
Halanaeroarchaeum sp. HSR-CO
Pathway
hahs00790
Folate biosynthesis
hahs01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
hahs00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HSRCO_1057 (folC)
Enzymes [BR:
hahs01000
]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.15 dihydropteroate synthase
HSRCO_1057 (folC)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HSRCO_1057 (folC)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Pterin_bind
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
UWG47345
LinkDB
All DBs
Position
complement(1024101..1026524)
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AA seq
807 aa
AA seq
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MRYDEAANFLLDLRRYRPKPGTASTADLLSWLDDPHEGPAHVQIAGSNGKGSTARMLERV
LSETDLDVGLYTSPHLDDFRERIRVNDRTITETAVTEFAERIRPRVVERAADNDAPTFFE
VMTTMALWYFDREDVDVAILEVGIGGRYDATSVVDPVASAVTSVTLEHTSVLGDTIEEIA
RDKATVAPAENPLVTGTTESALEAVSEVADSVTTVGDQDADVTATYGGITETYEASITLE
NADWTVETVIPLLGTHQATNAGIAAVLARQVTDVDESSIARGLRKATWPGRFEVVETDPA
VVLDGAHNPGGMAAVAGTLAELPYDDLHVVVGSMQDKDHVGMASALPTPDTVTTCRPDTD
RAEDQSVLEAVFDRVSDDVTAMSSVAAAVDRAIDEADADDCVLVTGSLFTIAEARRRWTR
RFVTRNVDSLADARRTLERAHVTPPGVWRMRAKGHHRVVSTRVQNRQAQYLKEEMLSLGG
ECSISGLNDQTEGYLDVVLMGTLAQFNRLVTKLDGQPYGLSVFADDLRRALDIRTPSRER
EYPWEDRPAIMGILNVTPDSFHDGGQYDTTEAAVERAREMVDAGVDIIDVGGESTRPGAE
PVAPTVERERVVPVIEALADLEVAVSVDTRDADVGRAALEAGADILNDVTGLDDPEMPFL
AAAFDVPLVVMHSIDAPVDPTRDVEYDDVIDDVIDELAEAVHRAERAGLDRSQIIIDPGL
GFGKSARENFALLDRIDEFHALGGPVLVGHSHKSMFAEIGLDADERGAATVAATALAADR
GADIVRVHDVKANLDAVSTVLATNRED
NT seq
2424 nt
NT seq
+upstream
nt +downstream
nt
atgcgttacgacgaggcggcaaacttcctcctcgacttacgccgctatcgacccaagccc
gggacggcgtcgacggcggaccttctctcgtggctcgacgacccccacgaggggccggcg
cacgtccagatcgccggttcgaacggcaaggggagcacggcacggatgctcgaacgcgtg
ctgtccgagaccgacctcgacgtcggactgtacacctctccacacctcgacgacttccgc
gaacggatccgggtgaacgaccggaccatcaccgagacggcggtcaccgagttcgccgaa
cgcatccgaccccgcgtcgtcgagcgcgcagcggacaacgacgccccgaccttcttcgag
gtgatgaccacgatggcgttgtggtacttcgaccgcgaggacgtcgacgtcgcgatcctc
gaggtcgggatcggtggacgctacgacgcgacgagcgtagtcgacccggtcgccagcgcg
gtcacgagcgtgacactggagcacacgagcgtcctcggagataccatcgaggagatcgca
cgcgacaaggcaaccgtcgccccggcggagaacccgctcgtcaccggcaccaccgagagc
gctctcgaagcggtctccgaggtggccgacagcgtgacgactgtcggtgaccaggacgcc
gacgtgaccgccacgtacggcggcataaccgaaacgtacgaggcgtcgatcacgctcgag
aacgcggactggaccgtggagaccgtaatcccactgctgggaacccaccaggcgacgaac
gccggtatcgccgccgtgctcgcgagacaggtcacggacgtcgacgaatcgtccatcgca
cgagggctcaggaaggcgacctggccggggcgcttcgaggtcgtggagacggatccggcc
gtcgtcctcgacggcgcgcacaatccgggcgggatggcggcggtcgccgggacgctcgcc
gagctaccgtacgacgacctccacgtcgtcgtcggatcgatgcaggacaaagaccacgtc
ggcatggcctcggccctcccgacgccggacaccgtcacgacctgtcggccggatacggac
cgcgcggaggaccagagcgtcctcgaggcggtcttcgaccgcgtcagtgacgacgtgacg
gcaatgagcagcgtggcggccgccgtcgacagggccatagacgaggccgacgccgacgac
tgcgtgctggtcactggctcgttgttcaccatcgccgaggcgagacggcggtggacgcgc
cgattcgtcacgcgaaatgtggattcactcgccgatgcgaggcggacactcgaacgggct
cacgtcaccccaccgggcgtctggcggatgcgagcgaaaggacaccaccgggtcgtctcg
acacgggtccagaaccgccaggcgcagtacctcaaagaggagatgctgtcgctgggcggg
gagtgttctatctccggtctcaacgaccagacggaaggatacctggacgtcgttctcatg
gggacgctcgcgcagttcaatcggctcgtgacgaaactcgacgggcaaccatacggtctc
tccgtcttcgccgacgacctccggagggccctggacatccgtacaccgtctcgagagcgg
gaatatccgtgggaggaccggccggcgatcatgggcatcctgaacgtcacgcccgacagt
ttccacgacggcggccagtacgacaccaccgaggcggccgtcgagcgggcacgggagatg
gtcgatgccggcgtcgacatcatcgacgtcggtggagagagcacccgaccgggagcggag
ccagttgcgcccacggtcgaacgcgaacgggttgtccccgtcatcgaggccctcgcggac
ctcgaggtagccgtctccgtcgatacccgcgacgccgacgtcggccgcgcggcactcgag
gccggtgcggacatcttgaacgacgtcaccgggctggacgaccccgagatgcccttcctc
gccgcagcgttcgacgtcccactggtcgtcatgcacagcatcgatgcacccgtcgatccg
acgagggatgtcgagtacgacgacgtcatcgacgacgtcatcgacgaactcgctgaagcg
gtccaccgcgccgaacgtgcgggcctggatcgctcgcagatcatcatcgatccggggctg
gggttcggcaagtcggcccgagagaacttcgccctcctcgaccggatcgacgagttccac
gcactgggcgggccggtcctcgtgggtcactcccacaagtcgatgttcgccgaaatcggg
ctggacgccgacgaacggggggcagcgactgtcgcggcgaccgccctggcagccgaccgt
ggcgcggacatcgttcgggtgcacgacgtgaaagcaaacctcgatgcggtgtcgacggtg
ctcgcgaccaaccgagaagactga
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