Halanaeroarchaeum sp. HSR-CO: HSRCO_2487
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Entry
HSRCO_2487 CDS
T09490
Symbol
leuB
Name
(GenBank) Isocitrate/isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
hahs
Halanaeroarchaeum sp. HSR-CO
Pathway
hahs00290
Valine, leucine and isoleucine biosynthesis
hahs00660
C5-Branched dibasic acid metabolism
hahs01100
Metabolic pathways
hahs01110
Biosynthesis of secondary metabolites
hahs01210
2-Oxocarboxylic acid metabolism
hahs01230
Biosynthesis of amino acids
Module
hahs_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
hahs_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
hahs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
HSRCO_2487 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HSRCO_2487 (leuB)
Enzymes [BR:
hahs01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
HSRCO_2487 (leuB)
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GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-ProteinID:
UWG48751
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Position
2361479..2362462
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AA seq
327 aa
AA seq
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MSEEIAVIPGDGIGQEVVPAAVAILETLDLGFSFTEAEAGDHVVEAGGEPLPSETRELAE
RADATLFGAAGESAADVILPLRAAVDSFVNVRPARTYPGIDAVRPETDIVFLRENTEGVY
SGHEDRLTEDVSTLTRVVTDSASRRLAEYACEFVGDRNEDGFTVAHKANVMRETDGRFRD
AVIDVADERGVQTEEVLMDALAMHLVLRPEEYDVVVTPNLAGDVLSDLAAGLVGGLGLLP
SANVGPERAVFEPVHGTAPDIAGEGIANPSATVLSAAMMLEYLGYDDEGAVVRDAVESVL
ADGPRTPDLGGTATTEDVTAALVDAIE
NT seq
984 nt
NT seq
+upstream
nt +downstream
nt
atgagcgaggagatcgccgtcatccccggcgatggcatcggccaggaggtcgtcccggcc
gccgtcgccatcctcgagacactcgatctcggcttctcctttaccgaggccgaggcgggc
gatcacgtcgtcgaggccgggggcgaaccgctcccgtccgagacccgggaactcgccgag
cgcgcggacgcgacactgttcggcgcggcgggcgagagcgccgccgacgtcatcctcccg
ctgcgcgcggccgtcgactccttcgtgaacgtgcggcccgcgcgaacctacccgggcatc
gacgccgtccgcccggagacggacatcgttttcctccgggagaacacggagggggtctac
tcgggacacgaggaccgtctcaccgaggacgtgagcacgctgacccgcgtggtcaccgac
tccgcctcgcgccgcctcgccgagtacgcctgcgagttcgtcggcgaccggaacgaagac
ggcttcacggtggcccacaaggcgaacgtgatgcgggagaccgacggtcggttccgcgac
gccgtcatcgacgtcgccgacgaacggggcgtccagaccgaggaggtcctcatggacgca
ctggcgatgcacctcgtgttgcgccccgaggagtacgacgtcgtcgtgacgccgaacctc
gcgggcgacgtgctctcggacctggcggcgggtctcgtgggcggtctgggactgctcccg
agcgcgaacgtcggccccgagcgggccgtcttcgaacccgtccacggtaccgcgccggac
atcgccggcgaggggatcgccaacccgagcgcgacggtcctctccgccgcaatgatgcta
gaatacctcggctacgacgacgagggtgcggtcgttcgcgacgcggtcgaatcggtcctg
gccgacggaccgcgcacgccggacctcggcggtacggcgacgaccgaggacgtcactgcg
gccctggtcgacgccatcgagtga
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