Hipposideros armiger (great roundleaf bat): 109379840
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Entry
109379840 CDS
T04661
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
hai
Hipposideros armiger (great roundleaf bat)
Pathway
hai00790
Folate biosynthesis
hai01100
Metabolic pathways
hai01240
Biosynthesis of cofactors
hai01523
Antifolate resistance
hai04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
hai00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
109379840 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
109379840 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
109379840 (FPGS)
Enzymes [BR:
hai01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
109379840 (FPGS)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
109379840
NCBI-ProteinID:
XP_019492362
UniProt:
A0A8B7QVQ0
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Position
Unknown
AA seq
630 aa
AA seq
DB search
MSRARSHLRAALFLAAVSPCGATTRTAARRELSARPAPLKPGMEYQDAVRTLNTLQTNAN
YLEQVKRQQDDPQTKLEAMKLYLARSGLQVEDLDRLNIIHITGTKGKGSTCAFTERILRS
YGLKTGFFRSPGSSPHLVQVRERIRINGQPISPELFTKHFWRLYHRLEETKDSKSCVSMP
AYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDT
VEEIAWQKGGIFKHGVPAFTVPQLDGPLAVLKERAEQVSCPLYLCPPLEALEEGGPPLTL
GLEGEHQRSNAALALQLARCWLQQKDHQGIRELEASRPSLLQRLQRLPLAPVFQPTSHMR
LALRDTEWLGRSQVLRRGHLTWYLDGAHTSSSMQACVRWFRQALLLGERRGSGPEVRVLL
FNSTGDRDPEALLKLLQPCQFDYAAFCPNLTEVSSTDNADDGTEARVGRCAQWTKALALK
LNCLALLLTSFVIADQQNFTVTLDQVLLRCLEHQQHWNHLDEKQASPGLWSTPSPEPGGP
ASLRLAPCPTHTRSTGSLVFSCISHALQWITQGRDPVFQPPSPPQGLLAHPVAGSGASIL
REAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgtcccgggcacgcagccacctgcgtgcggctctcttcctggcagcggtttccccgtgc
ggtgcaacgacccggaccgccgcgcggcgagagttgagcgctaggcccgcgccgctgaag
ccaggcatggagtatcaggatgctgtacgcacactcaacaccctgcagaccaatgccaac
tacctggagcaggtgaagagacagcaggatgacccccagacaaaactggaagccatgaag
ctgtacttggcacggagtgggctgcaggtggaggacttggaccggctgaacatcatccat
atcacagggaccaaggggaagggctccacctgtgccttcactgaacgtatcctccgaagc
tatggcctgaaaaccggattctttaggtctcccggtagctctccccacctggtgcaggtg
cgtgaacggatccgcatcaatgggcagcccatcagccccgagctcttcaccaaacacttc
tggcgcctctatcaccggctggaggagaccaaggatagcaagagctgtgtctccatgccc
gcctacttccgtttcctcacgctcatggccttccacgtcttcctccaagagaaggtggat
ctggcagtggtggaagtgggtatcggtggggcttacgactgcactaacatcatcaggaag
cctgtggtatgtggggtctcgtctcttggcatcgaccacactagcctcttaggggacaca
gtggaggagatcgcatggcagaaagggggcatcttcaagcatggcgtccccgccttcact
gtacctcagcttgacggtcccctggcagtgctgaaggagcgcgccgagcaggtctcatgt
cccctgtacctgtgcccgcccctggaagccctggaggaaggggggccaccgctgaccctt
ggcctggaaggagagcatcagcggtccaatgctgccttggccttgcagctggcccgctgc
tggctgcagcagaaggatcaccaaggcatcagggagctggaggcctccaggccgagcctc
ctgcagcggctgcagcggctgcctctggcgcctgtgttccagcccacatctcacatgcgg
cttgcgcttcgggacaccgagtggctgggccgttcgcaggtgctgcgacgcgggcacctc
acctggtacctggacggcgcgcatacctccagcagcatgcaggcctgcgtgcgctggttc
cgccaggcgctactcctcggcgagaggcggggcagcgggccagaggtgcgtgtcttgctc
ttcaactctaccggggaccgggatcccgaggccctgctgaagctgctgcagccctgccag
tttgactatgctgctttctgccctaacctgacagaggtgtcatccactgacaacgcagat
gatggcactgaggccagggtagggagatgtgctcagtggacaaaagccctagctctgaag
ctaaactgcctggctctgcttctcaccagctttgtgatagcggaccagcagaacttcaca
gtgacactggaccaggtgctgctccgctgcctggaacaccagcagcactggaaccacctg
gatgagaagcaggccagcccgggcctctggagcacccccagcccagagcctggtgggccc
gcctccctgcggctggcaccctgcccaacccatacccgcagcactggctcccttgtcttc
agctgcatctcccatgccttgcagtggatcacccaaggccgggacccagtctttcagcca
cccagtcccccgcagggcctcctagcccatcctgtggcaggcagcggggccagcatactc
cgtgaggctgctgccatccacgtgctggtcacaggaagcctgcacctggtgggcggtgtc
ctgaagctgctggagccctccctgtctcagtag
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