KEGG   Hipposideros armiger (great roundleaf bat): 109381083
Entry
109381083         CDS       T04661                                 
Symbol
AKT1
Name
(RefSeq) RAC-alpha serine/threonine-protein kinase
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
hai  Hipposideros armiger (great roundleaf bat)
Pathway
hai01521  EGFR tyrosine kinase inhibitor resistance
hai01522  Endocrine resistance
hai01524  Platinum drug resistance
hai04010  MAPK signaling pathway
hai04012  ErbB signaling pathway
hai04014  Ras signaling pathway
hai04015  Rap1 signaling pathway
hai04022  cGMP-PKG signaling pathway
hai04024  cAMP signaling pathway
hai04062  Chemokine signaling pathway
hai04066  HIF-1 signaling pathway
hai04068  FoxO signaling pathway
hai04071  Sphingolipid signaling pathway
hai04072  Phospholipase D signaling pathway
hai04140  Autophagy - animal
hai04150  mTOR signaling pathway
hai04151  PI3K-Akt signaling pathway
hai04152  AMPK signaling pathway
hai04210  Apoptosis
hai04211  Longevity regulating pathway
hai04213  Longevity regulating pathway - multiple species
hai04218  Cellular senescence
hai04261  Adrenergic signaling in cardiomyocytes
hai04370  VEGF signaling pathway
hai04371  Apelin signaling pathway
hai04380  Osteoclast differentiation
hai04510  Focal adhesion
hai04550  Signaling pathways regulating pluripotency of stem cells
hai04611  Platelet activation
hai04613  Neutrophil extracellular trap formation
hai04620  Toll-like receptor signaling pathway
hai04625  C-type lectin receptor signaling pathway
hai04630  JAK-STAT signaling pathway
hai04660  T cell receptor signaling pathway
hai04662  B cell receptor signaling pathway
hai04664  Fc epsilon RI signaling pathway
hai04666  Fc gamma R-mediated phagocytosis
hai04668  TNF signaling pathway
hai04722  Neurotrophin signaling pathway
hai04725  Cholinergic synapse
hai04728  Dopaminergic synapse
hai04810  Regulation of actin cytoskeleton
hai04910  Insulin signaling pathway
hai04914  Progesterone-mediated oocyte maturation
hai04915  Estrogen signaling pathway
hai04917  Prolactin signaling pathway
hai04919  Thyroid hormone signaling pathway
hai04920  Adipocytokine signaling pathway
hai04922  Glucagon signaling pathway
hai04923  Regulation of lipolysis in adipocytes
hai04926  Relaxin signaling pathway
hai04929  GnRH secretion
hai04931  Insulin resistance
hai04932  Non-alcoholic fatty liver disease
hai04933  AGE-RAGE signaling pathway in diabetic complications
hai04935  Growth hormone synthesis, secretion and action
hai04936  Alcoholic liver disease
hai04973  Carbohydrate digestion and absorption
hai05010  Alzheimer disease
hai05017  Spinocerebellar ataxia
hai05132  Salmonella infection
hai05135  Yersinia infection
hai05142  Chagas disease
hai05145  Toxoplasmosis
hai05152  Tuberculosis
hai05160  Hepatitis C
hai05161  Hepatitis B
hai05162  Measles
hai05163  Human cytomegalovirus infection
hai05164  Influenza A
hai05165  Human papillomavirus infection
hai05166  Human T-cell leukemia virus 1 infection
hai05167  Kaposi sarcoma-associated herpesvirus infection
hai05168  Herpes simplex virus 1 infection
hai05169  Epstein-Barr virus infection
hai05170  Human immunodeficiency virus 1 infection
hai05200  Pathways in cancer
hai05205  Proteoglycans in cancer
hai05207  Chemical carcinogenesis - receptor activation
hai05208  Chemical carcinogenesis - reactive oxygen species
hai05210  Colorectal cancer
hai05211  Renal cell carcinoma
hai05212  Pancreatic cancer
hai05213  Endometrial cancer
hai05214  Glioma
hai05215  Prostate cancer
hai05218  Melanoma
hai05220  Chronic myeloid leukemia
hai05221  Acute myeloid leukemia
hai05222  Small cell lung cancer
hai05223  Non-small cell lung cancer
hai05224  Breast cancer
hai05225  Hepatocellular carcinoma
hai05226  Gastric cancer
hai05230  Central carbon metabolism in cancer
hai05231  Choline metabolism in cancer
hai05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hai05415  Diabetic cardiomyopathy
hai05417  Lipid and atherosclerosis
hai05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109381083 (AKT1)
   04012 ErbB signaling pathway
    109381083 (AKT1)
   04014 Ras signaling pathway
    109381083 (AKT1)
   04015 Rap1 signaling pathway
    109381083 (AKT1)
   04370 VEGF signaling pathway
    109381083 (AKT1)
   04371 Apelin signaling pathway
    109381083 (AKT1)
   04630 JAK-STAT signaling pathway
    109381083 (AKT1)
   04668 TNF signaling pathway
    109381083 (AKT1)
   04066 HIF-1 signaling pathway
    109381083 (AKT1)
   04068 FoxO signaling pathway
    109381083 (AKT1)
   04072 Phospholipase D signaling pathway
    109381083 (AKT1)
   04071 Sphingolipid signaling pathway
    109381083 (AKT1)
   04024 cAMP signaling pathway
    109381083 (AKT1)
   04022 cGMP-PKG signaling pathway
    109381083 (AKT1)
   04151 PI3K-Akt signaling pathway
    109381083 (AKT1)
   04152 AMPK signaling pathway
    109381083 (AKT1)
   04150 mTOR signaling pathway
    109381083 (AKT1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    109381083 (AKT1)
  09143 Cell growth and death
   04210 Apoptosis
    109381083 (AKT1)
   04218 Cellular senescence
    109381083 (AKT1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109381083 (AKT1)
   04550 Signaling pathways regulating pluripotency of stem cells
    109381083 (AKT1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    109381083 (AKT1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    109381083 (AKT1)
   04613 Neutrophil extracellular trap formation
    109381083 (AKT1)
   04620 Toll-like receptor signaling pathway
    109381083 (AKT1)
   04625 C-type lectin receptor signaling pathway
    109381083 (AKT1)
   04660 T cell receptor signaling pathway
    109381083 (AKT1)
   04662 B cell receptor signaling pathway
    109381083 (AKT1)
   04664 Fc epsilon RI signaling pathway
    109381083 (AKT1)
   04666 Fc gamma R-mediated phagocytosis
    109381083 (AKT1)
   04062 Chemokine signaling pathway
    109381083 (AKT1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    109381083 (AKT1)
   04922 Glucagon signaling pathway
    109381083 (AKT1)
   04923 Regulation of lipolysis in adipocytes
    109381083 (AKT1)
   04920 Adipocytokine signaling pathway
    109381083 (AKT1)
   04929 GnRH secretion
    109381083 (AKT1)
   04915 Estrogen signaling pathway
    109381083 (AKT1)
   04914 Progesterone-mediated oocyte maturation
    109381083 (AKT1)
   04917 Prolactin signaling pathway
    109381083 (AKT1)
   04926 Relaxin signaling pathway
    109381083 (AKT1)
   04935 Growth hormone synthesis, secretion and action
    109381083 (AKT1)
   04919 Thyroid hormone signaling pathway
    109381083 (AKT1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    109381083 (AKT1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    109381083 (AKT1)
  09156 Nervous system
   04725 Cholinergic synapse
    109381083 (AKT1)
   04728 Dopaminergic synapse
    109381083 (AKT1)
   04722 Neurotrophin signaling pathway
    109381083 (AKT1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    109381083 (AKT1)
  09149 Aging
   04211 Longevity regulating pathway
    109381083 (AKT1)
   04213 Longevity regulating pathway - multiple species
    109381083 (AKT1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109381083 (AKT1)
   05205 Proteoglycans in cancer
    109381083 (AKT1)
   05207 Chemical carcinogenesis - receptor activation
    109381083 (AKT1)
   05208 Chemical carcinogenesis - reactive oxygen species
    109381083 (AKT1)
   05230 Central carbon metabolism in cancer
    109381083 (AKT1)
   05231 Choline metabolism in cancer
    109381083 (AKT1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109381083 (AKT1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    109381083 (AKT1)
   05212 Pancreatic cancer
    109381083 (AKT1)
   05225 Hepatocellular carcinoma
    109381083 (AKT1)
   05226 Gastric cancer
    109381083 (AKT1)
   05214 Glioma
    109381083 (AKT1)
   05221 Acute myeloid leukemia
    109381083 (AKT1)
   05220 Chronic myeloid leukemia
    109381083 (AKT1)
   05218 Melanoma
    109381083 (AKT1)
   05211 Renal cell carcinoma
    109381083 (AKT1)
   05215 Prostate cancer
    109381083 (AKT1)
   05213 Endometrial cancer
    109381083 (AKT1)
   05224 Breast cancer
    109381083 (AKT1)
   05222 Small cell lung cancer
    109381083 (AKT1)
   05223 Non-small cell lung cancer
    109381083 (AKT1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    109381083 (AKT1)
   05170 Human immunodeficiency virus 1 infection
    109381083 (AKT1)
   05161 Hepatitis B
    109381083 (AKT1)
   05160 Hepatitis C
    109381083 (AKT1)
   05164 Influenza A
    109381083 (AKT1)
   05162 Measles
    109381083 (AKT1)
   05168 Herpes simplex virus 1 infection
    109381083 (AKT1)
   05163 Human cytomegalovirus infection
    109381083 (AKT1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    109381083 (AKT1)
   05169 Epstein-Barr virus infection
    109381083 (AKT1)
   05165 Human papillomavirus infection
    109381083 (AKT1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    109381083 (AKT1)
   05135 Yersinia infection
    109381083 (AKT1)
   05152 Tuberculosis
    109381083 (AKT1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    109381083 (AKT1)
   05142 Chagas disease
    109381083 (AKT1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109381083 (AKT1)
   05017 Spinocerebellar ataxia
    109381083 (AKT1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109381083 (AKT1)
   05418 Fluid shear stress and atherosclerosis
    109381083 (AKT1)
   05415 Diabetic cardiomyopathy
    109381083 (AKT1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    109381083 (AKT1)
   04932 Non-alcoholic fatty liver disease
    109381083 (AKT1)
   04931 Insulin resistance
    109381083 (AKT1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    109381083 (AKT1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    109381083 (AKT1)
   01524 Platinum drug resistance
    109381083 (AKT1)
   01522 Endocrine resistance
    109381083 (AKT1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hai01001]
    109381083 (AKT1)
Enzymes [BR:hai01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     109381083 (AKT1)
Protein kinases [BR:hai01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   109381083 (AKT1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 PH_11 Seadorna_VP7
Other DBs
NCBI-GeneID: 109381083
NCBI-ProteinID: XP_019494949
UniProt: A0A8B7R1K8
LinkDB
Position
Unknown
AA seq 480 aa
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVEQRESPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEMMDF
RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFPEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMLCGRLPFYNQDHEKLFEL
ILMEEIRFPRSLSPEAKALLSGLLKKDPRQRLGGGPEDAKEIMQHRFFASIVWQDVYEKK
LCPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDNMECVDSERRPHFPQFSYSASGTA
NT seq 1443 nt   +upstreamnt  +downstreamnt
atgaacgacgtggccatcgtgaaagagggctggctgcacaaacgaggggagtacatcaaa
acctggcggccccggtacttcctgctgaagaacgatggcaccttcattgggtacaaggag
cggccgcaggacgtggagcagcgcgagtcgcccctcaacaacttctcagtggcgcaatgc
cagctgatgaagacggaacggccccggcccaacaccttcatcatccgctgcctgcagtgg
accacggtcatcgagcgcaccttccacgtggagacccccgaggaacgggaggagtggacg
accgccatccagacggtggccgacgggctcaagaagcaggaggaggagatgatggacttc
cggtcaggctcgcccagtgacaactcgggggccgaggagatggaggtgtccctggctaag
cccaagcaccgcgtgaccatgaatgagtttgagtacctgaagctgctgggcaaaggcacc
ttcgggaaggtgatcctggtgaaggagaaggccacaggccgctactacgctatgaagatc
ctcaagaaggaggtcattgtggccaaggacgaggtggctcacacgctcacagagaaccgc
gtcctccagaactcccggcaccccttcctgacggccctgaagtactccttccagacccac
gaccgcctctgcttcgtcatggagtacgccaacggcggcgagctcttcttccacctgtcg
cgggagcgggtgttccctgaggaccgggcgcgcttctacggggcggagatcgtgtcggcc
ctagactacttgcactcggagaagaacgtggtctaccgtgacctcaagctggagaacctc
atgctggacaaggatggacacatcaagatcaccgacttcgggctctgcaaggagggcatc
aaggacggtgccaccatgaagaccttctgcgggacccccgagtacctggcccccgaggtg
ctggaggacaacgactacggccgcgcggtggactggtggggactgggcgtggtcatgtac
gagatgctgtgcggccggctgcccttctacaaccaggaccacgagaagctgtttgagctc
atcctcatggaggagatacgcttcccgcgctcgctcagccctgaggccaaggccctgctg
tcagggctgctcaagaaggaccccaggcagcgtcttggagggggccccgaggacgccaag
gagatcatgcagcaccgcttcttcgccagcattgtgtggcaggacgtgtacgagaagaag
ctctgtccgcccttcaagccccaggttacgtcagagacagacaccaggtattttgacgag
gagttcaccgcccagatgatcaccatcacgccacctgaccaagacgacaacatggagtgc
gtggacagtgagcggaggccccacttcccccagttctcctactcggccagcggcacggcc
tga

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