KEGG   Hipposideros armiger (great roundleaf bat): 109381238
Entry
109381238         CDS       T04661                                 
Symbol
PIK3CD
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
hai  Hipposideros armiger (great roundleaf bat)
Pathway
hai00562  Inositol phosphate metabolism
hai01100  Metabolic pathways
hai01521  EGFR tyrosine kinase inhibitor resistance
hai01522  Endocrine resistance
hai01524  Platinum drug resistance
hai04012  ErbB signaling pathway
hai04014  Ras signaling pathway
hai04015  Rap1 signaling pathway
hai04024  cAMP signaling pathway
hai04062  Chemokine signaling pathway
hai04066  HIF-1 signaling pathway
hai04068  FoxO signaling pathway
hai04070  Phosphatidylinositol signaling system
hai04071  Sphingolipid signaling pathway
hai04072  Phospholipase D signaling pathway
hai04081  Hormone signaling
hai04140  Autophagy - animal
hai04150  mTOR signaling pathway
hai04151  PI3K-Akt signaling pathway
hai04152  AMPK signaling pathway
hai04210  Apoptosis
hai04211  Longevity regulating pathway
hai04213  Longevity regulating pathway - multiple species
hai04218  Cellular senescence
hai04360  Axon guidance
hai04370  VEGF signaling pathway
hai04380  Osteoclast differentiation
hai04510  Focal adhesion
hai04550  Signaling pathways regulating pluripotency of stem cells
hai04611  Platelet activation
hai04613  Neutrophil extracellular trap formation
hai04620  Toll-like receptor signaling pathway
hai04625  C-type lectin receptor signaling pathway
hai04630  JAK-STAT signaling pathway
hai04650  Natural killer cell mediated cytotoxicity
hai04660  T cell receptor signaling pathway
hai04662  B cell receptor signaling pathway
hai04664  Fc epsilon RI signaling pathway
hai04666  Fc gamma R-mediated phagocytosis
hai04668  TNF signaling pathway
hai04670  Leukocyte transendothelial migration
hai04722  Neurotrophin signaling pathway
hai04725  Cholinergic synapse
hai04750  Inflammatory mediator regulation of TRP channels
hai04810  Regulation of actin cytoskeleton
hai04910  Insulin signaling pathway
hai04914  Progesterone-mediated oocyte maturation
hai04915  Estrogen signaling pathway
hai04917  Prolactin signaling pathway
hai04919  Thyroid hormone signaling pathway
hai04923  Regulation of lipolysis in adipocytes
hai04926  Relaxin signaling pathway
hai04929  GnRH secretion
hai04930  Type II diabetes mellitus
hai04931  Insulin resistance
hai04932  Non-alcoholic fatty liver disease
hai04933  AGE-RAGE signaling pathway in diabetic complications
hai04935  Growth hormone synthesis, secretion and action
hai04960  Aldosterone-regulated sodium reabsorption
hai04973  Carbohydrate digestion and absorption
hai05010  Alzheimer disease
hai05017  Spinocerebellar ataxia
hai05020  Prion disease
hai05100  Bacterial invasion of epithelial cells
hai05132  Salmonella infection
hai05135  Yersinia infection
hai05142  Chagas disease
hai05146  Amoebiasis
hai05160  Hepatitis C
hai05161  Hepatitis B
hai05162  Measles
hai05163  Human cytomegalovirus infection
hai05164  Influenza A
hai05165  Human papillomavirus infection
hai05166  Human T-cell leukemia virus 1 infection
hai05167  Kaposi sarcoma-associated herpesvirus infection
hai05168  Herpes simplex virus 1 infection
hai05169  Epstein-Barr virus infection
hai05170  Human immunodeficiency virus 1 infection
hai05171  Coronavirus disease - COVID-19
hai05200  Pathways in cancer
hai05203  Viral carcinogenesis
hai05205  Proteoglycans in cancer
hai05206  MicroRNAs in cancer
hai05207  Chemical carcinogenesis - receptor activation
hai05208  Chemical carcinogenesis - reactive oxygen species
hai05210  Colorectal cancer
hai05211  Renal cell carcinoma
hai05212  Pancreatic cancer
hai05213  Endometrial cancer
hai05214  Glioma
hai05215  Prostate cancer
hai05218  Melanoma
hai05220  Chronic myeloid leukemia
hai05221  Acute myeloid leukemia
hai05222  Small cell lung cancer
hai05223  Non-small cell lung cancer
hai05224  Breast cancer
hai05225  Hepatocellular carcinoma
hai05226  Gastric cancer
hai05230  Central carbon metabolism in cancer
hai05231  Choline metabolism in cancer
hai05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hai05415  Diabetic cardiomyopathy
hai05417  Lipid and atherosclerosis
hai05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hai00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    109381238 (PIK3CD)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    109381238 (PIK3CD)
   04014 Ras signaling pathway
    109381238 (PIK3CD)
   04015 Rap1 signaling pathway
    109381238 (PIK3CD)
   04370 VEGF signaling pathway
    109381238 (PIK3CD)
   04630 JAK-STAT signaling pathway
    109381238 (PIK3CD)
   04668 TNF signaling pathway
    109381238 (PIK3CD)
   04066 HIF-1 signaling pathway
    109381238 (PIK3CD)
   04068 FoxO signaling pathway
    109381238 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    109381238 (PIK3CD)
   04072 Phospholipase D signaling pathway
    109381238 (PIK3CD)
   04071 Sphingolipid signaling pathway
    109381238 (PIK3CD)
   04024 cAMP signaling pathway
    109381238 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    109381238 (PIK3CD)
   04152 AMPK signaling pathway
    109381238 (PIK3CD)
   04150 mTOR signaling pathway
    109381238 (PIK3CD)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    109381238 (PIK3CD)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    109381238 (PIK3CD)
  09143 Cell growth and death
   04210 Apoptosis
    109381238 (PIK3CD)
   04218 Cellular senescence
    109381238 (PIK3CD)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109381238 (PIK3CD)
   04550 Signaling pathways regulating pluripotency of stem cells
    109381238 (PIK3CD)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    109381238 (PIK3CD)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    109381238 (PIK3CD)
   04613 Neutrophil extracellular trap formation
    109381238 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    109381238 (PIK3CD)
   04625 C-type lectin receptor signaling pathway
    109381238 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    109381238 (PIK3CD)
   04660 T cell receptor signaling pathway
    109381238 (PIK3CD)
   04662 B cell receptor signaling pathway
    109381238 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    109381238 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    109381238 (PIK3CD)
   04670 Leukocyte transendothelial migration
    109381238 (PIK3CD)
   04062 Chemokine signaling pathway
    109381238 (PIK3CD)
  09152 Endocrine system
   04910 Insulin signaling pathway
    109381238 (PIK3CD)
   04923 Regulation of lipolysis in adipocytes
    109381238 (PIK3CD)
   04929 GnRH secretion
    109381238 (PIK3CD)
   04915 Estrogen signaling pathway
    109381238 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    109381238 (PIK3CD)
   04917 Prolactin signaling pathway
    109381238 (PIK3CD)
   04926 Relaxin signaling pathway
    109381238 (PIK3CD)
   04935 Growth hormone synthesis, secretion and action
    109381238 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    109381238 (PIK3CD)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    109381238 (PIK3CD)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    109381238 (PIK3CD)
  09156 Nervous system
   04725 Cholinergic synapse
    109381238 (PIK3CD)
   04722 Neurotrophin signaling pathway
    109381238 (PIK3CD)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    109381238 (PIK3CD)
  09158 Development and regeneration
   04360 Axon guidance
    109381238 (PIK3CD)
   04380 Osteoclast differentiation
    109381238 (PIK3CD)
  09149 Aging
   04211 Longevity regulating pathway
    109381238 (PIK3CD)
   04213 Longevity regulating pathway - multiple species
    109381238 (PIK3CD)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109381238 (PIK3CD)
   05206 MicroRNAs in cancer
    109381238 (PIK3CD)
   05205 Proteoglycans in cancer
    109381238 (PIK3CD)
   05207 Chemical carcinogenesis - receptor activation
    109381238 (PIK3CD)
   05208 Chemical carcinogenesis - reactive oxygen species
    109381238 (PIK3CD)
   05203 Viral carcinogenesis
    109381238 (PIK3CD)
   05230 Central carbon metabolism in cancer
    109381238 (PIK3CD)
   05231 Choline metabolism in cancer
    109381238 (PIK3CD)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109381238 (PIK3CD)
  09162 Cancer: specific types
   05210 Colorectal cancer
    109381238 (PIK3CD)
   05212 Pancreatic cancer
    109381238 (PIK3CD)
   05225 Hepatocellular carcinoma
    109381238 (PIK3CD)
   05226 Gastric cancer
    109381238 (PIK3CD)
   05214 Glioma
    109381238 (PIK3CD)
   05221 Acute myeloid leukemia
    109381238 (PIK3CD)
   05220 Chronic myeloid leukemia
    109381238 (PIK3CD)
   05218 Melanoma
    109381238 (PIK3CD)
   05211 Renal cell carcinoma
    109381238 (PIK3CD)
   05215 Prostate cancer
    109381238 (PIK3CD)
   05213 Endometrial cancer
    109381238 (PIK3CD)
   05224 Breast cancer
    109381238 (PIK3CD)
   05222 Small cell lung cancer
    109381238 (PIK3CD)
   05223 Non-small cell lung cancer
    109381238 (PIK3CD)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    109381238 (PIK3CD)
   05170 Human immunodeficiency virus 1 infection
    109381238 (PIK3CD)
   05161 Hepatitis B
    109381238 (PIK3CD)
   05160 Hepatitis C
    109381238 (PIK3CD)
   05171 Coronavirus disease - COVID-19
    109381238 (PIK3CD)
   05164 Influenza A
    109381238 (PIK3CD)
   05162 Measles
    109381238 (PIK3CD)
   05168 Herpes simplex virus 1 infection
    109381238 (PIK3CD)
   05163 Human cytomegalovirus infection
    109381238 (PIK3CD)
   05167 Kaposi sarcoma-associated herpesvirus infection
    109381238 (PIK3CD)
   05169 Epstein-Barr virus infection
    109381238 (PIK3CD)
   05165 Human papillomavirus infection
    109381238 (PIK3CD)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    109381238 (PIK3CD)
   05135 Yersinia infection
    109381238 (PIK3CD)
   05100 Bacterial invasion of epithelial cells
    109381238 (PIK3CD)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    109381238 (PIK3CD)
   05142 Chagas disease
    109381238 (PIK3CD)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109381238 (PIK3CD)
   05017 Spinocerebellar ataxia
    109381238 (PIK3CD)
   05020 Prion disease
    109381238 (PIK3CD)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109381238 (PIK3CD)
   05418 Fluid shear stress and atherosclerosis
    109381238 (PIK3CD)
   05415 Diabetic cardiomyopathy
    109381238 (PIK3CD)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    109381238 (PIK3CD)
   04932 Non-alcoholic fatty liver disease
    109381238 (PIK3CD)
   04931 Insulin resistance
    109381238 (PIK3CD)
   04933 AGE-RAGE signaling pathway in diabetic complications
    109381238 (PIK3CD)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    109381238 (PIK3CD)
   01524 Platinum drug resistance
    109381238 (PIK3CD)
   01522 Endocrine resistance
    109381238 (PIK3CD)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hai04131]
    109381238 (PIK3CD)
Enzymes [BR:hai01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     109381238 (PIK3CD)
Membrane trafficking [BR:hai04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    109381238 (PIK3CD)
SSDB
Motif
Pfam: PI3_PI4_kinase PI3K_p85B PI3K_rbd PI3K_C2
Other DBs
NCBI-GeneID: 109381238
NCBI-ProteinID: XP_019495252
UniProt: A0A8B7R3N4
LinkDB
Position
Unknown
AA seq 616 aa
MPPGVDCPMEFWTKEENQSVLVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLTNSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSTSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQHLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVGRAGW
EAGARPRPVLQPRGHLAWGQPWEVRAASSLKPPLGSHKVSKAMVPNCPVPPPREALDRAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPF
ILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCS
KDIQYLKVKARAGPHQ
NT seq 1848 nt   +upstreamnt  +downstreamnt
atgccccccggggttgactgccccatggaattctggaccaaggaggagaatcagagcgta
ttggttgacttcctgctgcccacgggggtctatctgaacttccctgtgtcccgaaatgcc
aacctcagcaccatcaagaaggtattgtggcaccgagcccagtatgagccgcttttccac
atgctcagtgaccctgaagcctatgtgtttacctgcgtcaaccagaccgcggagcagcag
gagctggaggacgagcagcggcggctgtgtgacatccagcccttcctgcccgtcctgcgc
ctggtggcccgggagggcgacagggtgaagaagctcaccaactctcagatcagcctcctc
attggcaaaggcctccatgagtttgactcgctgcgggacccggaagtgaatgactttcga
gctaagatgcgccagttctgcgaggaggcggctgcccgccggcagcagctgggctgggag
gcctggctacaatacagctttcctctgcagctggagccctcggcacggagctgggggcct
ggcaccctgcgggtccccaaccgggccctcctggtcaatgtcaagttcgagggcagtgag
gagagcttcaccttccaggtgtccactaaggacgtgcccctggcactgatggcctgcgcc
ctccggaagaaggccacggtgttccggcagcccctggtggagcagcccgaggactacacc
ctgcaggtgaacgggaagcatgaatacctgtatggcagctaccccctctgccagttccag
tatatctgcagctgcctgcacagcgggctgaccccacacctgaccatggtacattcctcc
tccatcctcgccatgcgggacgaacagagcaaccctgccccccaagtccaaaaaccacgc
accaaaccgccccccattcccatgaagaagccctcctctacatccctgtggtccctggaa
cagcctttctgcatcgagctgatccagggcagcaaagtgaatgccgacgagcggatgaag
ctggtggtacaggccgggctgttccacggcaacgagacattgtgcaagacggtctccagc
tccgaggtgagcgtgtgctcggagcccgtgtggaagcagcacctggagtttgacatcaat
gtgtgcgacctgccacgcatggcccgtctctgctttgcgctgtacgctgtgatcgagaag
gccaagaaggctcgctctaccaagaagaagtccaagaaggcggtgggtcgggctggctgg
gaggctggggccaggccccgtccagtcctgcagccccggggccacttagcctggggacag
ccctgggaggtccgtgcggcctcctcgttgaagcctccgctcgggagccacaaggtttct
aaggccatggttcccaattgccccgtccccccacccagggaggccttggatcgagccatc
gaggagttcaccctttcctgcgctggctactgtgtggccacatatgtgctgggcattggc
gatcggcacagcgacaacatcatgatccgagagaatgggcagctgttccacattgatttt
ggccactttctggggaatttcaagaccaagtttggaatcaaccgggagcgagtcccattc
atcctcacctatgactttgtccatgtgattcaacaggggaagactaataatagtgagaaa
tttgaaaggttccgaggctactgtgaaagagcgtacaccatcctgcgtcgccatggactg
ctgttcctccacctctttgccctgatgcgggcagcaggcctgcctgagctcagctgctcc
aaggacatccagtatctcaaggtaaaggccagggcagggccccaccag

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