Hipposideros armiger (great roundleaf bat): 109381262
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Entry
109381262 CDS
T04661
Symbol
MTOR
Name
(RefSeq) serine/threonine-protein kinase mTOR
KO
K07203
serine/threonine-protein kinase mTOR [EC:
2.7.11.1
]
Organism
hai
Hipposideros armiger (great roundleaf bat)
Pathway
hai01521
EGFR tyrosine kinase inhibitor resistance
hai01522
Endocrine resistance
hai04012
ErbB signaling pathway
hai04066
HIF-1 signaling pathway
hai04072
Phospholipase D signaling pathway
hai04136
Autophagy - other
hai04140
Autophagy - animal
hai04150
mTOR signaling pathway
hai04151
PI3K-Akt signaling pathway
hai04152
AMPK signaling pathway
hai04211
Longevity regulating pathway
hai04213
Longevity regulating pathway - multiple species
hai04218
Cellular senescence
hai04371
Apelin signaling pathway
hai04613
Neutrophil extracellular trap formation
hai04630
JAK-STAT signaling pathway
hai04659
Th17 cell differentiation
hai04714
Thermogenesis
hai04910
Insulin signaling pathway
hai04919
Thyroid hormone signaling pathway
hai04920
Adipocytokine signaling pathway
hai04930
Type II diabetes mellitus
hai04931
Insulin resistance
hai04935
Growth hormone synthesis, secretion and action
hai05010
Alzheimer disease
hai05014
Amyotrophic lateral sclerosis
hai05016
Huntington disease
hai05017
Spinocerebellar ataxia
hai05022
Pathways of neurodegeneration - multiple diseases
hai05163
Human cytomegalovirus infection
hai05165
Human papillomavirus infection
hai05167
Kaposi sarcoma-associated herpesvirus infection
hai05168
Herpes simplex virus 1 infection
hai05170
Human immunodeficiency virus 1 infection
hai05200
Pathways in cancer
hai05205
Proteoglycans in cancer
hai05206
MicroRNAs in cancer
hai05207
Chemical carcinogenesis - receptor activation
hai05210
Colorectal cancer
hai05212
Pancreatic cancer
hai05214
Glioma
hai05215
Prostate cancer
hai05221
Acute myeloid leukemia
hai05224
Breast cancer
hai05225
Hepatocellular carcinoma
hai05226
Gastric cancer
hai05230
Central carbon metabolism in cancer
hai05231
Choline metabolism in cancer
hai05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
hai05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
hai00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
109381262 (MTOR)
04371 Apelin signaling pathway
109381262 (MTOR)
04630 JAK-STAT signaling pathway
109381262 (MTOR)
04066 HIF-1 signaling pathway
109381262 (MTOR)
04072 Phospholipase D signaling pathway
109381262 (MTOR)
04151 PI3K-Akt signaling pathway
109381262 (MTOR)
04152 AMPK signaling pathway
109381262 (MTOR)
04150 mTOR signaling pathway
109381262 (MTOR)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
109381262 (MTOR)
04136 Autophagy - other
109381262 (MTOR)
09143 Cell growth and death
04218 Cellular senescence
109381262 (MTOR)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
109381262 (MTOR)
04659 Th17 cell differentiation
109381262 (MTOR)
09152 Endocrine system
04910 Insulin signaling pathway
109381262 (MTOR)
04920 Adipocytokine signaling pathway
109381262 (MTOR)
04935 Growth hormone synthesis, secretion and action
109381262 (MTOR)
04919 Thyroid hormone signaling pathway
109381262 (MTOR)
09149 Aging
04211 Longevity regulating pathway
109381262 (MTOR)
04213 Longevity regulating pathway - multiple species
109381262 (MTOR)
09159 Environmental adaptation
04714 Thermogenesis
109381262 (MTOR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109381262 (MTOR)
05206 MicroRNAs in cancer
109381262 (MTOR)
05205 Proteoglycans in cancer
109381262 (MTOR)
05207 Chemical carcinogenesis - receptor activation
109381262 (MTOR)
05230 Central carbon metabolism in cancer
109381262 (MTOR)
05231 Choline metabolism in cancer
109381262 (MTOR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
109381262 (MTOR)
09162 Cancer: specific types
05210 Colorectal cancer
109381262 (MTOR)
05212 Pancreatic cancer
109381262 (MTOR)
05225 Hepatocellular carcinoma
109381262 (MTOR)
05226 Gastric cancer
109381262 (MTOR)
05214 Glioma
109381262 (MTOR)
05221 Acute myeloid leukemia
109381262 (MTOR)
05215 Prostate cancer
109381262 (MTOR)
05224 Breast cancer
109381262 (MTOR)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
109381262 (MTOR)
05168 Herpes simplex virus 1 infection
109381262 (MTOR)
05163 Human cytomegalovirus infection
109381262 (MTOR)
05167 Kaposi sarcoma-associated herpesvirus infection
109381262 (MTOR)
05165 Human papillomavirus infection
109381262 (MTOR)
09164 Neurodegenerative disease
05010 Alzheimer disease
109381262 (MTOR)
05014 Amyotrophic lateral sclerosis
109381262 (MTOR)
05016 Huntington disease
109381262 (MTOR)
05017 Spinocerebellar ataxia
109381262 (MTOR)
05022 Pathways of neurodegeneration - multiple diseases
109381262 (MTOR)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
109381262 (MTOR)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
109381262 (MTOR)
04931 Insulin resistance
109381262 (MTOR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
109381262 (MTOR)
01522 Endocrine resistance
109381262 (MTOR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hai01001
]
109381262 (MTOR)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hai04131
]
109381262 (MTOR)
Enzymes [BR:
hai01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
109381262 (MTOR)
Protein kinases [BR:
hai01001
]
Serine/threonine kinases: Other
PIKK family [OT]
109381262 (MTOR)
Membrane trafficking [BR:
hai04131
]
Autophagy
Other autophagy associated proteins
mTORC1 complex
109381262 (MTOR)
mTORC2 complex
109381262 (MTOR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
FAT
PI3_PI4_kinase
FRB_dom
mTOR_dom
FATC
HEAT_ATR
TPR_19
UME
Motif
Other DBs
NCBI-GeneID:
109381262
NCBI-ProteinID:
XP_019495297
UniProt:
A0A8B7R3S6
LinkDB
All DBs
Position
Unknown
AA seq
1646 aa
AA seq
DB search
MIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSL
SHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVK
SHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMH
DNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEVPLPSRKAALETVDRLTE
SLDFTDYASRIIHPIVRTLDQSPELRPTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRI
NHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHVSTIN
LQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVS
CWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLG
ERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELE
IQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLV
NDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCI
DKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQ
GCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQ
LDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELH
KLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHY
KHQNQARDEKKKLRHTSGANITSAATAATTAATATATATSTEGSNSESEAESSENSPTPS
PLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEAL
VEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKST
TTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERN
VKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDL
YYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVI
TSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQ
RYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQK
VEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSN
LMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTV
MEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVEL
GEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDETLDVPT
QVELLIKQATSHENLCQCYIGWCPFW
NT seq
4941 nt
NT seq
+upstream
nt +downstream
nt
atgatcgaccagtcccgggatgcttctgctgtcagcctgtcagaatccaagtccagccag
gattcctctgactacagcaccagtgaaatgctggtcaacatgggaaacctgcccctggac
gagttctaccccgccgtgtccatggtggcgctgatgcggatcttccgggaccagtccctt
tctcaccatcacaccatggttgtccaggccatcaccttcatcttcaagtccctggggctc
aagtgtgtgcagttcctgccccaggtcatgcccacattcctgaatgtcattcgggtctgc
gacggggccatccgggaatttctgttccaacagctgggaatgttggtgtcatttgtgaag
agccacatcagaccttatatggatgaaatcgtcacccttatgagagagttctgggtcatg
aacacctcaatccagagcacgatcattcttctcattgagcaaattgtggtagctcttggg
ggtgaatttaagctctacctgcctcagctgattccacacatgttgcgcgtcttcatgcat
gataacagcccaggccgcatcgtctccatcaagttgctggctgcaatccagctgtttggc
gccaacctggatgactatctacatttgttgttgccccctatcgtgaagttgtttgatgcc
cctgaagttccactgccatctcgaaaggcagccttagagacagtggaccgcctgacggag
tccctggatttcaccgactatgcctcccggatcattcacccaattgttcggacgctggac
cagagcccagaactgcgccccacagccatggacacgctgtcttcactcgtctttcagctt
gggaagaagtaccaaattttcattccaatggtgaataaagttctggtgcgacaccgaatc
aaccatcagcgctatgatgtcctcatctgcaggattgtcaagggctacacccttgccgat
gaagaggaggaccctttgatttaccagcatcgaatgctgaggagtggccagggggatgca
ttggctagtgggccagtggaaacaggacccatgaagaaactgcacgtcagcaccatcaac
ctccaaaaggcctggggagctgccagaagggtctccaaagatgactggctggaatggctg
aggcggctaagcctggagctgttaaaggactcctcgtcgccctccctgcgctcatgctgg
gccctggctcaggcctacaaccctatggccagggatctcttcaatgctgcatttgtgtcc
tgctggtctgaactgaatgaagaccaacaggatgaactcatcagaagcatcgagttggcc
ctcacctcacaggacatcgctgaagtcacacaaaccctcttgaacttggctgaattcatg
gaacacagtgacaagggccccctgccactgagagacgacaatggcattgttttgctgggt
gagagggctgctaagtgccgagcatacgccaaagcgctacactacaaagaactggagttc
cagaaaggtcccacccctgccatcctagagtctctcatcagcattaataataagctacag
cagccggaggcagctgccggggtgttagaatatgccatgaaacacttcggagagttggag
atccaggctacctggtacgagaaactgcacgagtgggaggacgcccttgtagcctatgat
aagaaaatggacaccaacaaggatgacccagagctgatgctgggccgcatgcgctgcctc
gaggccttgggggaatgggggcagctccatcagcagtgctgtgaaaagtggaccctggtt
aacgatgagacccaagccaagatggcccgaatggctgctgcagctgcatgggggttaggt
cagtgggacagcatggaagagtacacctgtatgatccctcgggatactcatgatggggca
ttttatagagctgtgctggcattacatcaggacctcttctccctggcacaacagtgcatt
gacaaagccagggacctgctggatgcagagctaacggccatggcaggagagagctacagc
cgggcatatggggccatggtttcttgccatatgctctccgagctggaggaggtcatccag
tacaaacttgtccccgagcgacgagagatcatccgccagatctggtgggagagactgcag
ggctgccagcgcatcgtggaggactggcagaaaatcctcatggtgcggtcccttgtggtc
agcccccacgaggacatgaggacctggctcaagtatgcaagtctgtgtggcaagagcggc
aggctggctcttgctcataaaaccttagtgttgctcctgggagtcgatccgtctcggcag
cttgaccatcctctgccaacagttcaccctcaagtgacctacgcctacatgaaaaacatg
tggaagagtgctcgcaagattgatgccttccagcacatgcagcacttcgttcagaccatg
cagcagcaggcccagcatgccatcgccaccgaggaccagcagcacaagcaagagctgcac
aagctcatggcccgttgtttcctgaaacttggggagtggcagctgaacctccagggcatc
aacgagagcaccatccccaaagtcctgcagtattacagcgctgccacggagcacgaccgc
agctggtacaaggcctggcacgcgtgggcagtgatgaatttcgaagccgtgctgcactac
aaacaccagaaccaggcccgggacgagaagaagaagctgcgtcacaccagtggggccaac
atcaccagtgcggccacagccgccaccacggcggccacggccaccgccactgccaccagc
accgagggcagcaacagcgagagcgaggccgagagcagcgagaacagcccgacgccctct
cccctgcagaagaaggtcactgaggacttgtccaaaaccctcttgatgtacactgtccct
gccgtccagggcttcttccgttctatctccttgtcacgaggcaacaacctccaggatacg
ctcagagttctcaccttatggtttgattatggtcactggccagatgtaaatgaagccttg
gtggaaggggtgaaagcaatccagattgacacttggttacaggttatacctcagcttatt
gcaagaattgatacacccaggcccttggtgggacgtctcattcaccagcttctcacagac
attggtcggtaccacccccaggcactcatctaccccctgactgtggcttctaagtcgacc
accacagcccgtcacaacgcagccaacaagattctgaagaacatgtgtgagcacagtaac
accttggtgcagcaggccatgatggtgagtgaggagctgatccgagtggccatcctctgg
catgagatgtggcacgaaggcctggaggaagcttctcgtttgtactttggggagaggaac
gtgaaaggcatgtttgaggtgctggagcccctgcacgccatgatggaacgaggaccccag
actctgaaggaaacctcctttaaccaggcatatggtcgggatttaatggaggcccaagag
tggtgccggaaatacatgaaatcggggaatgtcaaggacctcacccaagcctgggacctc
tattatcacgtgttcagacgaatctcaaagcagctgccacagctcacatccttagagctg
cagtatgtttcccccaaacttctgatgtgccgtgaccttgagttggctgtgccaggaacc
tatgaccccaaccagccgatcattcgcattcagtccatagcaccatctctgcaagtcatc
acgtccaagcagaggccccggaagttgacacttatgggcagcaacgggcacgagtttgtc
ttcctcctgaagggccatgaagacctgcggcaggacgaacgagtgatgcagctcttcggc
ctggtcaacacccttctggccaacgacccaacctctctccggaaaaacctcagcatccag
agatacgcagtcattcccttatcaaccaactcgggcctcatcggctgggtcccccactgt
gacacgctgcacgccctcatccgggactacagggagaaaaagaagatccttctcaacatt
gagcatcgcatcatgttgcggatggctccagactacgatcacctgactctgatgcagaag
gtagaggtgtttgagcacgctgtcaataacacagcgggggacgacctggccaagctgctg
tggctgaaaagccccagctccgaggtgtggtttgatcgaagaaccaattacacccgctct
ttagcagtcatgtccatggtcgggtatattttgggcctgggagatagacacccatccaac
ctgatgctggaccggctgagtgggaagatcctgcacattgactttggggactgctttgag
gttgctatgaccagagagaaatttccagaaaagattccgtttagactaacgagaatgttg
accaacgctatggaggttaccggtctggatggcaactacagaatcacgtgccacacagtg
atggaagttcttcgggaacacaaggatagtgtcatggctgtgctggaagcctttgtctac
gaccccttgctgaactggaggctgatggacacaaataccaaaggcaacaagcgatcccga
acaaggacagattcctactctgctggccagtccgtagaaattttggatggtgtggaactt
ggggaaccagcccataagaaaacggggaccacagtgccagaatctattcattctttcatt
ggagatggcctggtcaaacctgaggccctaaataagaaagctattcaaattattaacaga
gttcgagataagctcactggtcgggacttctctcatgatgaaacgttggatgtcccaaca
caagttgagctgctcatcaaacaagcaacgtcccatgaaaacctctgccagtgctacatt
ggctggtgtcctttctggtaa
DBGET
integrated database retrieval system
