Hipposideros armiger (great roundleaf bat): 109390613
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Entry
109390613 CDS
T04661
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
hai
Hipposideros armiger (great roundleaf bat)
Pathway
hai00310
Lysine degradation
hai01100
Metabolic pathways
hai05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
hai00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
109390613 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
109390613 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hai03036
]
109390613 (DOT1L)
Enzymes [BR:
hai01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
109390613 (DOT1L)
Chromosome and associated proteins [BR:
hai03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
109390613 (DOT1L)
HMT complexes
Dot1-containing complex
109390613 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
109390613
NCBI-ProteinID:
XP_019512829
UniProt:
A0A8B7SLG9
LinkDB
All DBs
Position
Unknown
AA seq
1724 aa
AA seq
DB search
MRHSVLILSDPWKMTGRGNLQRRLVSWDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAAPADTPVDSGAEEEKVGTTAIKKPSPSKARKKKLNKKGRKLAGRKRGRPKKMSTA
NPERKPKKSPTALDLLHSQTMSQTAAASPQDAYKSPHSPFYQLPPTVQRQPPDQLLLAPI
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYSDLIQAQKEISAHNQQLREQTEQLDKDNRELRTQSLQLL
KARCEELKLDWSTLSLENLLKEKQALRSQISEKQRRCLELQISIVELEKSQRQQELLQLK
SCVPPDDAVPGHLRGKSGLGRELEAEPGRLHLELDCSKLSLPHFSSMSPELSMNGHVSGY
ELCSALSRPSSKQNTPQYLASPLDQEVVPCTPGHSSRPRLERLSGLALPDYTRLSPAKLV
LRRHLSQDHAANSKAAAGELHPRAEHTKENSLPYHSPGLTNGIKLSPQYPRSSSPMSLQM
TGEKGSEKGLKERTYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRST
PSPVPQARESSSTLEKQMGANAHGAGSKGLALAPAGFSYTGSVAISGALAGSPAPLVSGA
EPPAFDESSSSGSLFATMGSRSSTPQHPPLLVQPRNSGPASPAHQLCASPRLGTAQGPLP
DASKGDLPSEAGFSDPESEAKRRTIFTISAGTSSTKQSPSNKHSPLPASIRGDSSQSHGQ
DSRKRGRRKRASAGTPSLSSGVSPKRRALPSVASLFTQSSGSPLNLNSMVNNINQPLEIT
AISSPESSLKSSPVPYQDNDQPPVLKKEKPLNQTNGAQYSPLTSDEEPGSEDEPGSARIE
RKIATISLESKSPPKTLENGGGLAGRKPVPASEPVNSSKWKATFSPISDLSLAKATDSPL
QASSTLGQNSLFAFRPTLEEPSSVDAKLASHPRKSFPSALSAAGGLSPNSNPPNGFAFSG
GLATDLSLHSFNDGASLSHKAPEVASLGTPLSFPALRGKEGSTESGPFVNKRQLDGLNSL
KGEGGKGREAELGLPSCTPSDKASLAHGKAGKGRDREPDFKNGHNLFISAAAVPPGGLLS
GPGLATAASSAGNMASSAQTHRPFLGTFAPSPQFSLGPMSLQANLGSSVLQSLFSSVPAA
AGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGVFNHAVPSASSHPFGASFGSGAACRSA
TLSLTPLQAVASTPASSFQAPPSLEPRQPPPQPLGRPPAGPPTLHVPLPPNAALPPAHAL
LPANSEPALLQNLAPLPANQAFLPVSSAASLPPANASLSIKLASLPHKASRPSFTVHHQP
LPGLALAQAAPVIPQASSTGPSAVWVSLGMPPPCAARLAGVKPR
NT seq
5175 nt
NT seq
+upstream
nt +downstream
nt
atgaggcattctgtcctaatcttgagtgacccttggaaaatgacaggaagaggaaattta
caaaggcgtctggtctcctgggacaaacaccatgatgctgctcatgaaatcattgagacc
atccgatgggtctgtgaggaaatcccagacctcaagctcgctatggagaattacgtccta
atcgactacgacaccaaaagctttgaaagcatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagctgtggaagggcaccacgcaacccatgaagctgaacacg
cggccgtccaatgggctcctgcggcacatcctgcaacaggtctacaaccattcagtgacg
gaccccgagaagctcaacaactatgagcctttctcccctgaggtgtatggggagacctcc
tttgacctggtcgcacaaatgattgacgagatcaagatgaccgaggatgacctgtttgtg
gacctgggcagtggagtgggccaggtcgtgctgcaggtcgccgcggccaccaactgcaaa
catcactacggcgtcgagaaagccgacatcccagccaagtatgcggagaccatggaccga
gagttcaggaagtggatgaaatggtacggaaaaaagcatgcagaatacacactggaaaga
ggcgatttcctctcggaagagtggagagagcggatcgccaacacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaacatg
aaggaaggtggcagaatcgtgtcctcgaagcccttcgcacctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgtgtggtggagctgtcgccgctgaaa
ggctcggtgtcatggacggggaagccagtgtcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggaacaagaggca
gctcggcgccggcagcagcgagaaaacaagagtaacacaaccacccccacgaaggtgccc
gagagcaaggcagctgcgcctgcggacacccctgtggattctggtgctgaggaagagaaa
gtggggacaactgccatcaagaagccatccccctccaaagcccggaagaagaagctgaac
aaaaaggggcggaagctggccggccggaagcgcgggcgccccaaaaagatgagcactgcg
aaccctgagcgtaagcccaagaagagcccgactgcactggacctgctgcattctcagacc
atgtcccagactgccgccgcctcgccgcaagatgcgtataagtcacctcacagcccgttt
tatcagctacctcccactgtgcagcggcagccacctgaccagctgctgctggcacccatc
ccgcctgcactgcagaagctgctagagtcctttaagattcagtacctgcagttcttggca
tacacgaagacccctcagtacaaggccagcctgcagcagctactggaccaggagaaggag
aagaacgcccgcttgctgggcgctgcacagcagctgtttggccactgccaggcccagaaa
gaggagatcaagaggcttttccagcagaaactagatgagttgggagtgaaggcgctgacc
tacagcgacctgatccaggcgcagaaggagatctcggctcacaaccagcagctacgggag
cagacggagcagctagacaaggataatagggagctgcgcacccagagcctgcagctgcta
aaggctcggtgtgaggaactgaagctagactggtctacgctgtccctggagaacctgctg
aaggaaaagcaggcactgaggagccagatctccgagaagcagagacgctgcctggagctg
cagatcagcattgtggagctggagaagagtcagcggcaacaggagctcctgcagctcaag
tcctgcgtgccgcctgatgacgcagtgcctggtcaccttcgcgggaagagtggcctgggc
cgtgagctggaggcagagcctggccggctgcacctggagctggactgctccaagctctca
ctgccccattttagtagcatgagcccggagctctccatgaatggccatgtgtctggctat
gagctctgcagtgcgctgagccggccctcgtccaagcagaacaccccccagtacctggcc
tcaccgctggaccaggaggttgtgccctgcacccccggccacagcagccgaccccggctc
gagaggctgtcgggcctggccctgcctgactacaccaggctctcacccgccaagctggta
ctcagacgccacctgagtcaggaccatgcggccaacagtaaggctgctgctggcgagctg
cacccacgagctgagcacactaaggagaacagccttccataccacagcccgggcctcacc
aacggcatcaaactgagccctcagtacccacggtcctcatcccccatgtccttacagatg
acaggagagaagggcagtgagaagggtctgaaggagcgcacctatgctagcagtggggag
gccattaccagcctgcctgtcagcatcccgctcagcaccgtgcagcccagcaagctgccc
gtcagcatccccctggccagcgtggtgctgcccagccgcgccgagaaggtgagaagcacc
cccagccctgtgccacaggcacgagagtcctcatccacacttgagaagcagatgggtgct
aatgcccatggcgctggaagcaaagggcttgccctggcccccgcaggtttctcctacacc
ggctcggtggccatcagcggggccctggcaggcagcccggccccgcttgtttctggagcc
gagcccccagcctttgacgagtcctctagctcagggagcctctttgccaccatgggctcc
cgcagctctaccccgcagcatcccccactgctggtacagccccggaactctggcccggcc
tcccctgcccaccagctctgcgccagcccccggcttggcactgcccagggcccgcttcct
gacgccagcaaaggggaccttccctccgaggctggcttctcagatccagagagcgaggcc
aagaggaggaccatcttcaccatctcggctggcaccagcagcaccaagcagtcgccttcc
aacaagcacagccctctgcctgcgagtatccgcggggacagcagccagagccacgggcag
gacagccgcaagcggggcaggaggaagcgggcgtcagcaggaacccccagcctgagctcg
ggtgtgtcccccaagcgccgggccctgccatccgtcgccagcctcttcacacagtcttca
gggtcccctctcaaccttaactccatggtcaacaacatcaaccaacctttggaaatcacg
gccatctcgtcccccgagagctccctaaagagctctcctgtcccttaccaggacaacgac
cagccacccgtgctcaagaaagagaagcccctgaaccaaaccaatggggcccagtattcc
ccgctgacctcagatgaggagccgggctctgaggatgagccgggcagtgccagaatcgag
agaaaaattgcaacgatctccttagaaagcaaatctcctccaaaaaccttggaaaatggt
ggtggcctggcgggaagaaagccagtgcccgccagcgagcctgtcaacagcagcaagtgg
aaggccaccttctcgcccatctccgacctcagcctggccaaggccactgacagcccacta
caggccagctccactctgggccagaactccctgtttgctttccggcccaccctagaggag
cccagctcagttgacgccaagctggcctcccaccccaggaagagcttccccagtgccctg
tcggcggccggtgggctgagcccaaacagcaaccctcccaatggcttcgccttcagtggg
ggcctggccactgacctcagtttacacagcttcaacgatggtgcttctctctcccacaag
gcccccgaggtggccagcctgggcacccccctgagctttcccgccctgcggggcaaggag
ggcagcacagagtctggcccctttgtgaacaagaggcagctggacggactgaacagcctg
aagggcgaggggggcaagggcagggaggcagagctgggcctgccctcatgcacgccctca
gacaaggcctcactggcacatggcaaggcaggcaagggccgggaccgcgagcctgacttc
aagaacggccacaacctcttcatttctgctgccgccgtgccccccgggggcctcctcagc
ggcccgggccttgccacagcagcatcttcggcgggcaacatggcctcctctgcccaaaca
caccggcccttcctgggcaccttcgcacccagcccgcagttctccctgggccccatgtcc
ctgcaggccaacctgggatcatccgtgctgcagtccctgttcagctctgtgccggctgcc
gccggcctggtgcatgtctcgtccgctgcgaccagactgaccaactcacacgccatgggc
agtttttcatccggggtggcaggcggcgcagttggaggtgtctttaaccacgcggtgcct
tccgcctcctctcatccgtttggagccagtttcggcagcggggctgcgtgtcgcagtgcc
acgctgagcttaaccccgctgcaggcggtggccagcacccccgcctcttcctttcaggcc
ccgccctccctggagccgcggcagcccccaccccagcccctgggccggccccctgcgggg
ccgcctaccctccacgtgccccttcctcctaacgccgccttgcctcccgctcatgcgctg
ctccctgctaactctgagcccgcgctcctgcagaacctggctcccctccctgctaaccaa
gctttcttacccgtctcctctgccgcttctctgccgcctgctaacgcctctctgtccatc
aagctcgcctccctcccgcacaaggcctcccgcccctccttcacggtgcaccaccagccc
ctgcctgggctggccctggcccaggctgcgcccgtgatcccacaggccagctccacgggg
ccatccgctgtgtgggtttcccttggcatgccgcctccttgtgccgcgcgccttgcgggg
gttaagccgcgataa
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integrated database retrieval system
