KEGG   Hipposideros armiger (great roundleaf bat): 109392215
Entry
109392215         CDS       T04661                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
hai  Hipposideros armiger (great roundleaf bat)
Pathway
hai01522  Endocrine resistance
hai04010  MAPK signaling pathway
hai04012  ErbB signaling pathway
hai04014  Ras signaling pathway
hai04024  cAMP signaling pathway
hai04068  FoxO signaling pathway
hai04071  Sphingolipid signaling pathway
hai04137  Mitophagy - animal
hai04140  Autophagy - animal
hai04141  Protein processing in endoplasmic reticulum
hai04210  Apoptosis
hai04215  Apoptosis - multiple species
hai04217  Necroptosis
hai04310  Wnt signaling pathway
hai04380  Osteoclast differentiation
hai04510  Focal adhesion
hai04530  Tight junction
hai04620  Toll-like receptor signaling pathway
hai04621  NOD-like receptor signaling pathway
hai04622  RIG-I-like receptor signaling pathway
hai04625  C-type lectin receptor signaling pathway
hai04657  IL-17 signaling pathway
hai04658  Th1 and Th2 cell differentiation
hai04659  Th17 cell differentiation
hai04660  T cell receptor signaling pathway
hai04664  Fc epsilon RI signaling pathway
hai04668  TNF signaling pathway
hai04722  Neurotrophin signaling pathway
hai04723  Retrograde endocannabinoid signaling
hai04728  Dopaminergic synapse
hai04750  Inflammatory mediator regulation of TRP channels
hai04910  Insulin signaling pathway
hai04912  GnRH signaling pathway
hai04914  Progesterone-mediated oocyte maturation
hai04917  Prolactin signaling pathway
hai04920  Adipocytokine signaling pathway
hai04926  Relaxin signaling pathway
hai04930  Type II diabetes mellitus
hai04931  Insulin resistance
hai04932  Non-alcoholic fatty liver disease
hai04933  AGE-RAGE signaling pathway in diabetic complications
hai04935  Growth hormone synthesis, secretion and action
hai04936  Alcoholic liver disease
hai05010  Alzheimer disease
hai05012  Parkinson disease
hai05016  Huntington disease
hai05017  Spinocerebellar ataxia
hai05020  Prion disease
hai05022  Pathways of neurodegeneration - multiple diseases
hai05132  Salmonella infection
hai05133  Pertussis
hai05135  Yersinia infection
hai05142  Chagas disease
hai05145  Toxoplasmosis
hai05152  Tuberculosis
hai05161  Hepatitis B
hai05162  Measles
hai05166  Human T-cell leukemia virus 1 infection
hai05167  Kaposi sarcoma-associated herpesvirus infection
hai05169  Epstein-Barr virus infection
hai05170  Human immunodeficiency virus 1 infection
hai05171  Coronavirus disease - COVID-19
hai05200  Pathways in cancer
hai05208  Chemical carcinogenesis - reactive oxygen species
hai05210  Colorectal cancer
hai05212  Pancreatic cancer
hai05231  Choline metabolism in cancer
hai05415  Diabetic cardiomyopathy
hai05417  Lipid and atherosclerosis
hai05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hai00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    109392215 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109392215 (MAPK8)
   04012 ErbB signaling pathway
    109392215 (MAPK8)
   04014 Ras signaling pathway
    109392215 (MAPK8)
   04310 Wnt signaling pathway
    109392215 (MAPK8)
   04668 TNF signaling pathway
    109392215 (MAPK8)
   04068 FoxO signaling pathway
    109392215 (MAPK8)
   04071 Sphingolipid signaling pathway
    109392215 (MAPK8)
   04024 cAMP signaling pathway
    109392215 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    109392215 (MAPK8)
   04137 Mitophagy - animal
    109392215 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    109392215 (MAPK8)
   04215 Apoptosis - multiple species
    109392215 (MAPK8)
   04217 Necroptosis
    109392215 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109392215 (MAPK8)
   04530 Tight junction
    109392215 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    109392215 (MAPK8)
   04621 NOD-like receptor signaling pathway
    109392215 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    109392215 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    109392215 (MAPK8)
   04660 T cell receptor signaling pathway
    109392215 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    109392215 (MAPK8)
   04659 Th17 cell differentiation
    109392215 (MAPK8)
   04657 IL-17 signaling pathway
    109392215 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    109392215 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    109392215 (MAPK8)
   04920 Adipocytokine signaling pathway
    109392215 (MAPK8)
   04912 GnRH signaling pathway
    109392215 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    109392215 (MAPK8)
   04917 Prolactin signaling pathway
    109392215 (MAPK8)
   04926 Relaxin signaling pathway
    109392215 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    109392215 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    109392215 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    109392215 (MAPK8)
   04722 Neurotrophin signaling pathway
    109392215 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    109392215 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    109392215 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109392215 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    109392215 (MAPK8)
   05231 Choline metabolism in cancer
    109392215 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    109392215 (MAPK8)
   05212 Pancreatic cancer
    109392215 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    109392215 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    109392215 (MAPK8)
   05161 Hepatitis B
    109392215 (MAPK8)
   05171 Coronavirus disease - COVID-19
    109392215 (MAPK8)
   05162 Measles
    109392215 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    109392215 (MAPK8)
   05169 Epstein-Barr virus infection
    109392215 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    109392215 (MAPK8)
   05135 Yersinia infection
    109392215 (MAPK8)
   05133 Pertussis
    109392215 (MAPK8)
   05152 Tuberculosis
    109392215 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    109392215 (MAPK8)
   05142 Chagas disease
    109392215 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109392215 (MAPK8)
   05012 Parkinson disease
    109392215 (MAPK8)
   05016 Huntington disease
    109392215 (MAPK8)
   05017 Spinocerebellar ataxia
    109392215 (MAPK8)
   05020 Prion disease
    109392215 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    109392215 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109392215 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    109392215 (MAPK8)
   05415 Diabetic cardiomyopathy
    109392215 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    109392215 (MAPK8)
   04936 Alcoholic liver disease
    109392215 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    109392215 (MAPK8)
   04931 Insulin resistance
    109392215 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    109392215 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    109392215 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hai01001]
    109392215 (MAPK8)
Enzymes [BR:hai01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     109392215 (MAPK8)
Protein kinases [BR:hai01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   109392215 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH DUF530
Other DBs
NCBI-GeneID: 109392215
NCBI-ProteinID: XP_019516050
UniProt: A0A8B7SV89
LinkDB
Position
Unknown
AA seq 427 aa
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagtaagcgtgacagcaatttttatagtgtagagattggagactctacattc
acagtcctgaaacgataccagaatttaaaacctataggctcaggagctcaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccggcca
tttcagaatcaaactcatgctaagcgggcatacagagagctagttcttatgaagtgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaatcattcatcgggacttaaagcccagtaatatagtagtaaaa
tcagactgcactttgaagattcttgactttggactggccaggactgcaggaactagtttt
atgatgacaccttacgtagtgacccgctactacagagcgcctgaagtcatcctagggatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgtcctgaattcatgaagaaactacaaccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccctgatgtacttttc
ccagctgactcggaacacaacaaacttaaagccagtcaggcaagggatttgttatccaaa
atgctggtaattgacgcatctaaaaggatctctgtcgatgaagctctccaacacccatac
atcaatgtctggtatgacccttctgaagcagaagctccaccaccaaagatacctgacaag
cagttagatgaaagagaacacacaatagaagaatggaaagaattgatatacaaggaagtt
atggacttggaggagagaaccaagaatggagttatacggggacagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcgtcgtctgtcaatgatgtctct
tcaatgtcaacagatccgactttggcctcagacacagacagcagtctggaagcatcggcc
gggcctctgggctgctgtagatga

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