Hemitrygon akajei (red stingray): 140733261 Help Entry 140733261         CDS       T11019                                  Symbol mdn1 Name (RefSeq) midasin   KO K14572   midasin Organism haka  Hemitrygon akajei (red stingray) Pathway haka03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:haka00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     140733261 (mdn1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:haka03009]     140733261 (mdn1) Ribosome biogenesis [BR:haka03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     140733261 (mdn1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA AAA_3 AAA_16 AAA_7 nSTAND3 AAA_22 TsaE AAA_6 ABC_tran AAA_14 Sigma54_activat Rad17 Sigma54_activ_2 AAA_29 RsgA_GTPase DUF815 bpMoxR Dynein_heavy MDN1_4th AAA_28 PduV-EutP VWA AAA_8 ATPase AAA_21 Motif Other DBs NCBI-GeneID:  140733261 NCBI-ProteinID:  XP_072912476 LinkDB All DBs Position 9:75201425..75357943 Genome browser AA seq 5566 aa AA seqDB search MGDMAFQLAALPLIAKLNERSRSELNKYLAKQIWNKQDRQCILNTLAQLLLDKECTLLIG RHLRPLLLDLLERNVKAIKAPAFNHDLHERLCVAMSKLIDVSPDVILFALRYFKDSPPVF QRLFLESSDSNTVRYGRKRMKLRDLMSAACKFLKENWIIFSELWDWSVCLPLLGSHDTVV RWYTARCLAVVTNMSDEQKNHFFKKILTTEELTNFRLQLLEDELLFNVEKALVLANVKTG LWQKEKQQKYTQGQILSGDLSENVVAVCGVVVPRNQPAQKGQVCIHRSLVLVASTYGYLQ NLAMAVLSQNAVLLEGPIGCGKTALVEYLAAVTGRQKAPDFLKVQLGDQTDSKMLLGMYR CADVPGEFVWQPGSLTQAVMNGYWILLEDIDYAPLDVISVLIPLLETGELLIPGHGDCIK AAPGFQFFATRRVFSSNVGWYRQQNTHATLLDKLWTKIKLDNMNRAELKEVLVNRYSSLE IVIDRLLDIYCQLTGKKHQELQIKPAGNHENMDLDDCEAKVEEKDLCLEGRGLSLRDLLK WCERIIPNFDGTSSSTALCIFQEALDCFTAMISKHKSRQKMAEIIGSKLNISKEKAQYFC QLYKPAVELNEAAVTVGRAVLPRKSSDIIQLQLQTQTFSATRPSSLLLEQLAVCLGKGEP VLLVGETGTGKTSTVQYLAKITGHKLRVVNMNQQSDTADLLGGYKPMDRKLIMLPLREAF EELFIQTYSRKQNATFLGHVQMCCKQKRWQDLLQLMLHVYKTAVSKELKSKENGACLKEK WELLGLRLAQAQQQMKLSESSLVFAFVEGTLAQAVKKGEWILLDEINLASAETLECLSGL LEGNTSSLVLLDRGDTEPIHRDPEFRLFACMNPATDIGKRNLPPGIRNRFTELYVDELEA EGDLQILVSDYLRGLNVSKKTIQGIIEFYLTVRKEADIKLMDGTGHRPHYSLRTLCRALK FSALNSYNNIQRSLYEGFCMSFLTQLDRISHPVVEKLICHHVIGTNAKSVLQQPISEPKG GGAVQIEGYWIATGDKEPTIDKLYILTPSVKLNLRDLVRVVAARIHPVLIQGETSVGKTS LINWLASATGNHCVRINNHEHTDIQEYLGCYASDDMGKLVFKEGVLINAMRKGHWIILDE LNLAPTEVLEALNRLLDDNRELFIAETQEVVKAHPRFMLFATQNPPGQYGGRKVLSRAFR NRFVELHFDELPSAELEVIIHKRCSLPPSYCAKLVKVMLDLQSYRRGSNVLAGKHGFITL RELFRWAERYRLSDVTAQNYDWIRHIATDAFMLLAGRVRKEEEVAVIRQILEKQFKKRLV PEILFSKENLEKKLSHWSSLRSVMPDNFHHVVWTYGMRKLAILVGQALQFGEAVLLVGET GCGKTTICQMFAALFNQKLHTVNCHLHLETSDFLGGLRPVRHTSGENDGDNPSKLFEWHD GPLVLAMKEDDMFLMDEISLADDSVLERLNSVLEAEQTLLLAEKGSGEDDQVELVTGGNK FRILATMNPGGDFGKKELSPALRNRFTEIWCPPCDSRDDLMEIVQHNLCPKLSLDGEDNK GKDIAELILDFIDWLKNQEFGRRCVLSIRDILSWVNFMNVTTERVTSDVDLDDRTTFNLD PVTAFIHAACLICIDGIGSGSTVCSPEATLAARKACLEFLFKKLSVITHLKKHMKSMLNS YDEKRKRKILWTEHYFGIHPFYIPIEGTGGEKLALEDYALNAGTTAMNAQRVLRALKLNR PILLEGSPGVGKTSLVAALAKASGNTLVRINLSEQTDVTDLFGTDLPVEGGKGGEFAWRD GPLLGALKAGHWIVLDELNLASQSVLEGLNACFDHRAEVFIPELGFSFSVQHKKTKIFAC QNPYRQGGGRKGLPKSFLNRFTQVYVDQLSVTDMEYIADTIFPAIGKNIISKMVNFSHKV NQEIIVERKWGQKGGPWEFNLRDLFRWCQLMLVDQTAGCYDPGQHVALVYADRMRTEADR RNMFAVFERIFSNGDANQLYPYSQSRKFHITPQQFQVGYSILSRHAVSVPMSSKRLSILH HSLQPLESVMKCVQMNWMTILVGPAASGKTSLIQLLALLMGQNLKVMAMNSAMDTTELLG GFEQVDILRPWQSLIRKVKDFVLAVTKNVLLSLDSFHDGSNLLKLWNSFLNSHSQSLDKD HRSGISSEAVNKLENLLTVLHQCNNKLNTFSSSEFEELIAEFQQFNHLHSQFLNGEKRGT FEWVDGMLVQALISGDWLLLDNVNFCSPSVLDRLNALLEPGGVLTISERGVIDGTCPTVV PHPNFRLFMTMDPVHGEISRAMRNRGIEIYIAGEQNSEPLDEHDMKMLLHGLGLMGDHPC TELMALYSEIKEIAVAGISISSFLRAAVLIVQQLKCGLDLPEAFVRACLEVFASSQTSQV HQKQVQELVKKHGLTLASPEFRAHSLTILGLWPDSVPSAMLTAEDSMLSMVYRDGQVLTY CLNQLSLKNNRFQPLTLTDLEVVLQSCNMDHLSFHGNWTAAQVASEVDMIPTAVRMVTEK ASNQDWLLRARWLCHVAKSHKQLPDLVFAQLEAGSQGLNAVYSSALPTGMKDVIQQLQPN AKDIASVPLDPRWNQQQLVILFHSVNFENGEHRLKELQAQLSSVANRMAFLMNREERVYM EKTILASEATKKSGRRSALRISIAFHKGMLSFENLPHPALAHLAAFFEIWDACVLQCIKS QLYHLEDDVFNEVLCNAVWRDRFWVVSDRVTLDSEGMALLSLHWHWVLKHLVKDHLQQLS CVSQISQEIHTVSVNLQSHLASPSGITFGVKKMQKSLGFPPPFKAESVVEWTSKLKSISS VLDVLSLRPKVTDIAWKDQLCRIKAVTTDWNIKKELLLAWGLVLRANHFAGFDTDEIQRV VNTITSVMKSQGLLNSSDSKSVEPTPPQLDGDCLNQLQSNIQLWPAVEYLALLCKFKVLA DLLDLSLISGSRIKQDKSKICAELRQLVTFCIRTTPGSARALQGFWYLIETELPAEELNL LCSELISSVYGACWTSSLSTDPDYWLTWKSSKSLENDGTLEAFTDKSLKGPAVLCQAIQS KCFFEVLIGGQYNRGAIEGIVGAAASHVSLGEWQERTKQLQEISTILWTNMAVNSFAEFR FTDSRLQRIVLHKQLQAVKHLLPREIQEEYLKTCDQLVFDKDDTACDSVLSSLKGLAGHG VLPEDIVSLFVTCIQEFLGKEKDFASLSKQAQSGCLWVYLGLLQILIWTPQTKFDPAVKK MYKLNYINEELQQLESEWKSRNLSEHLFTGREHSQEGENKHCHPRIRFLQQRIKQLKERA TVLSRKQAYRPNVPSYISLYQDIHHYMLSIGHGSRIKTLLFRLLQHLLVKRPKTRQSFQT MLKEEAAWQQSQHHFRRRIAEEYWQYPDVVEPLNAAVLQMQHGMRLLTSEVHLALNHKCV NQADLTRLVTCLLVFPSISFEFPTYYSLAETLSSKTCIETIQGLDELLSKNLSAKSEEKT LLKEQRTLLTQEQLLFNALQYLRCHILSVGELDQASLQLLRHLFQAMVNAWDEQEECRRL KEEQEASLYKYKSKQHGLSVLEEEEKEFRQNFPQYSKDFTDITSQPSLEQQEMDTEVKIT EAKAKRSAPISPGSIEMLIKIHQQIYLGCAQSMWYHQGAPAHQSSDYLGAFVSSYHTAAV LITEFYSLIDASMSGQLHGSQLLMSSLIQNAVSEEGNSELTLPQEETYDFYHHPNILEVK KCQPVLRNLTQKVKELLIDWPDHPALLQLLVVMDRIRGFPISSPLAKFLSGMEILLSKAQ DWEQNASRSVSLREHLDAITHLIIQWRKLELNCWNDSLDIVRKRQMEKSSNHWFSLYQLV EKYLQKQAGEDLKEVAGGMTLSEVIKILQAFIEGATLAEFHFRLSVLLAFHCHVLVVPEQ EGKDALCSLLWNLYNYYKQFSETIASKITECRSPIEKELKDYIRICRWNDVSYWAVKQSV EKAHRTLFKLMKKFETALQQPCRPALTELGRTGSLGSVDQQKWTKIEKLNCTLRKVFTEK WDSTQAIFPNLGKSILYKDANSLQTHLPVLCKRMRKLCLKLVMKSSLPRLVESLDQFAGD VITGAQDLQALAVDQNADKDVQKSEVKHILMQKQRALADLFKHLAEIGLSYRKGLAWSRT KDLQDMLCLRPLDVKTAINMVESSDELDNMLLQEIAATWDGCQKYFYQSLARRAALQTAL RTPTKELSLGTVERCQGFTAHLLKLLIKQRRRLTRLTEQWVSLRHLIKSVQEIQTRLAGF KDHDVALPPQNGIKLWMDQLRALFMKLIITLEQTLWFMQCCPKHQTAEAHQDMPIGTQKV DSCEGDLESTSVATASLPENFVQFHLTVPTPFVANHFPDACNMQQGDAAWKQVTSQIANV LKDVKVAKAEMDEMNHQTNKTLLYSWTCFETCSSGIGCLSRTVVHLQDIQAIFAVAGSQS TCCPVLFSSLEYIKKEASCAVTEFTTWEKELLNLTFDDSSVDSEMDFSPLVEPVINTVLC AVQTVLKGQKEEAEQEQGQVMGNENEDEAKVRSIPTGYLSEVLEHQMANDISSLNLKKVT AAVSDLLKKLIDHRQECTIEEYQLFNQNCRSIVRLLPMLTSYSELILYYLMVSITTHRST GKLLSILTHLFTDLAMQGFCLPKELMEDAGGEGSTQFHDNEGGGIGEGEGMKDVSDKIEK EDQVEDTFCKDQEKKEDPENMPDVKDEENAIEMSEDFDGKLHDGEPKEQGEQDNDEESDS DEEEELDKQMGDLGDAEADKLDERLWGGDDDDDDDDASDKAEETGPGMDMEQSELVAKDD NMEAANQNDSDTKKQEEEEKKEREESKDKIHEQLDEREYDENEVDPYQGKQKQPEVEALD LPDDLNLENQDGDKSEDEHEEEGDNPYDIEEKLMDFNEVPADEEDQKMEESSEQEKTEDH SQTGDETEEKNQKEDDEEKSENPDQKLPEEETSENLEEEQLAKQDEQNESGREDTGVPDE GLQSETDDNMEDQDVPESKQRMEHEAAGKTGEENLQSDTAVEVAGSATERDQAKEEQGCG AADANQSEGHESKLTARFASQRQSQDKTQSYKRKPGHADNERTMGDRNERVSKRLKTVEA DSAQQQDTAQSEQGVKEADIYEHVKEGCDSYDTQTYDAATTEQQKVGGAGQEEQDEDSES IEMETIQEEELECVDVQELKPEKEKSSTSTASGYDNLEAELHPPKPEDIDDTKDDSSDSE KELSTERSRESTIHTRHELLTEDMEQSTVPDPEELRKQLEEQLSAWQNEEAGDPEQEKAA AAMWQQYQTLTAPLSQQLCEQLRLILEPTQAAKLRGDYRTGKRLNMRKVIPYIASQFRKD KIWLRRTKPSKRQYQICLAIDDSSSMVDNHSKQLAFEALAVIGNALSLLEVGQVAVCSFG ESVQLLHPFHEQFSDQSGARILRSCQFQQKKTKIAQFLESAANMFVAAQHHSQQGNPEIA QLLLIVSDGRGLFLEGKERVTTAVRAARHNNIFVIFVVLDNPDSKDSILDIKVPIFKTPG EMPEIRSYMEEFPFPFYVILRDVNALPETLSDALRQWFELVTAADY NT seq 16701 nt NT seq  +upstreamnt  +downstreamnt atgggagacatggcctttcagctggcggcccttcctctcattgccaagttgaacgagagg agccgcagcgagctgaacaagtacttggccaagcagatttggaacaagcaggatcggcag tgtatcctcaatactctggctcagctgctgttggataaagaatgcacgctgctgatagga cgccatctcaggcctttgctgttggatcttcttgagcgcaatgtgaaggcgatcaaagca cctgcatttaaccatgatctacatgagagactgtgtgtagcaatgagcaagctcattgat gtcagccctgatgtcattttgtttgctctgaggtatttcaaggattctcccccagtattt cagagattgtttctggagagttcagattcaaatacagtccgatatggtcggaagcgaatg aaactccgagacctcatgagtgcagcgtgcaaattcttgaaggaaaactggataatattc agtgagttatgggactggagtgtctgccttccactgctgggaagccatgataccgtagtc cgttggtacacagctagatgtcttgcagttgtaacaaatatgagtgatgaacaaaagaac cacttcttcaagaaaattctcactacagaagaactgacaaattttaggctacagctattg gaagatgaactgttgtttaatgttgagaaggcgttggttctggcaaatgtaaagactggt ttgtggcagaaagagaaacaacaaaaatatacccagggacaaatactgtctggagatctg tctgagaatgttgttgcagtatgtggagttgtagtaccacggaaccagcccgcccaaaaa ggccaagtatgcatccataggtctcttgtgttagtggcttcaacctatggctatctacag aacctggctatggcagtcctgtcccagaatgctgtgttgctggaaggaccaattggctgt ggtaaaactgctttagtagaatatttagcagcagtaacgggccgacagaaggctcctgac ttcttgaaagttcagcttggagaccagactgatagtaagatgttactaggaatgtatcgc tgtgctgatgttccaggggagtttgtttggcagcctggatcactgactcaagctgtgatg aatggatattggattctcttggaagacattgactatgcacctttagatgttatatctgtg ctgatacctttgctggagacaggagagcttttaattcctggacatggtgattgtataaaa gcagctcctggttttcagttttttgcaacaagaagggtgttcagtagcaatgtgggttgg tatagacaacaaaacactcatgcaactttgttggacaaactatggactaaaatcaaattg gataatatgaacagagcagaattaaaagaggtgttagtaaaccgatattcaagcctagaa attgtgattgaccggcttttggacatatactgccaactaactggcaagaagcatcaagaa ttacaaatcaagccagctggaaatcatgaaaatatggatttggatgattgtgaagcaaaa gttgaagaaaaagacttgtgccttgaaggaaggggattatctttaagagatttgctgaaa tggtgtgagagaataattcctaattttgatgggacatcatcttctactgccctctgcatc ttccaggaggcacttgattgtttcacagccatgatatctaagcataagagcaggcagaaa atggctgaaatcattggaagcaaactaaatatttcaaaagaaaaggcacaatacttctgt cagttatataaacctgccgttgagctgaatgaggctgcagtgactgtgggccgggctgtt cttcctcgaaaaagtagcgatatcatccagttacagttgcaaacgcagaccttttcagct acaagaccctcgtctctcctcctggagcagctggctgtttgccttggcaaaggggaacct gttttattggtcggtgaaacaggtactggtaaaacatctactgtccagtaccttgccaaa attacaggccacaagctgagggttgtaaacatgaaccaacagagtgacacggcagatttg cttggaggatacaagccaatggatcgaaaactaattatgttacccttgcgtgaagcattt gaagagcttttcattcagacgtactccaggaagcagaatgccacttttttgggtcatgtt caaatgtgctgcaaacagaaacgctggcaagatttactacaactgatgctacatgtttac aaaacagctgtcagtaaggagttgaaatccaaagaaaatggtgcctgtttgaaagagaaa tgggaattacttggtttgcgcctggctcaggctcagcagcagatgaagctgagtgaatct tcattggtatttgcctttgtggagggaaccttagcccaggctgtgaaaaagggagaatgg attttgttggatgagatcaacttggcttcagcagagacgctggaatgtctcagtgggcta ttggaagggaatacgagttctcttgtgctgttagatcgaggagatactgagcccatacat cgtgacccagagtttcgcttgtttgcctgcatgaatccggcaacagatataggaaagaga aacttgccaccaggcatacgaaatcggtttacagaactatatgttgatgaactggaagct gaaggagatctccaaatccttgtatctgattatctaagggggttaaatgtcagcaagaaa actattcaagggatcattgagttttacttaactgtccgtaaggaggcagatattaagtta atggatggaactgggcataggccccactatagccttcggactctctgccgtgctctcaaa ttttctgcactgaactcttacaacaacattcaacgctcattatatgagggcttctgtatg agttttctgactcagctggatcggatatctcacccagtcgttgagaagttaatttgtcat catgtcattggaactaatgccaaatctgttcttcagcagcccatctctgaaccaaaagga ggaggagctgtgcagattgaaggctactggattgcaacaggagataaagaacctaccatt gataagctatatattcttacaccctctgtcaaactcaacttgagagatctagtgagagtg gttgcagcaagaattcatcccgtgcttattcaaggagaaacatcagttggtaaaaccagt ctgattaactggttggcatctgctactggaaaccattgtgtacggatcaataatcatgaa cacacagatattcaggaatatcttggctgctatgcatctgacgacatgggcaaattagta tttaaagaaggtgtgcttattaatgccatgcgaaaaggccattggataattcttgatgaa ttgaatttggccccaactgaagtgttggaagcactcaatcgactacttgatgacaatcgt gagctctttatagcagagacacaagaagtagtaaaagcacatccaagattcatgcttttt gcaactcagaaccctcctggacagtatggaggtagaaaggttttgtcaagagcatttaga aaccgttttgtggaattgcattttgatgaacttccaagtgctgaattagaagtgataatt cacaagagatgctctttgcctccatcatactgtgcaaaattggttaaagttatgctggat ttgcagtcatatcgcagaggttcaaatgttttggctggaaaacatggcttcattactttg cgagagctgtttaggtgggccgagcgctacagattgtctgatgtaacagcacaaaattat gactggattcggcatatagctactgacgcttttatgctcttggctggccgtgtgagaaag gaggaagaagttgctgttattcgacaaattcttgaaaaacaatttaagaagaggcttgtt cctgaaattctattttcaaaagaaaatcttgagaaaaaattgagtcactggtcaagtctg aggtcagttatgcctgacaattttcaccacgttgtgtggacatatggtatgaggaaactt gcaatattggtgggtcaggctttgcagtttggagaagctgtgctccttgttggagaaact gggtgtggtaagacgacaatctgtcagatgtttgctgccttgttcaatcagaagctgcat acagtaaactgtcatctacacctagagacatcagacttccttgggggcctcaggcctgtc agacatacttctggtgaaaatgatggcgacaaccccagcaagctttttgagtggcacgat ggtcctcttgtacttgccatgaaggaagatgacatgtttctgatggatgaaatctctttg gcagatgactctgttttggaaagactgaatagcgtcctggaagctgaacagacacttttg cttgcagaaaagggaagtggggaagatgatcaagtggagcttgtaactggtggaaacaaa tttaggattcttgcaaccatgaatcctggtggtgattttggtaagaaagagctttcacca gctttgaggaacagatttactgagatctggtgcccaccatgcgatagccgtgatgatttg atggagattgttcaacataacctgtgtcccaagctttctttagatggagaagataataaa ggcaaagatattgctgaactcattttggatttcattgactggctaaaaaatcaagagttt ggtcgtcgatgtgtattgagtattcgtgatattctgtcttgggtcaacttcatgaatgtt acaactgagagagtgacttcagatgtggatttggatgatagaactacatttaatctcgat cctgtcactgcattcatacatgctgcctgtctcatttgtattgatggcattggatcaggg tctacagtttgttctcctgaagctacactggctgctcgcaaagcatgcttggaatttctt tttaaaaagctgtctgtgatcacacatttgaaaaaacatatgaagagtatgctgaacagt tatgatgagaaaaggaagaggaaaattttatggactgaacactactttggaattcatcct ttttacattcccatagaagggacaggtggagaaaagctggcgcttgaagactatgcattg aatgctggcacgactgcaatgaatgctcagagagtgttgagagccctgaagttaaacagg ccaattcttctggagggatcaccaggagttggaaagacaagcctggtggcagctttggca aaggcttctggaaacacacttgtccgaattaacctttctgaacaaacggatgtgactgat ttgtttgggacagacctgcccgttgagggtggtaaaggtggagagtttgcttggcgagat ggccctctgcttggggctttgaaggctggacattggattgttttagatgagttaaacttg gcttctcagtctgtactggagggactcaatgcttgttttgatcatcgtgctgaggttttt atccctgagctgggatttagtttcagtgtacaacataagaagaccaagatctttgcctgt cagaatccttaccgacaaggaggtggaaggaaaggactccccaagtcatttctcaacaga tttacacaggtttatgtggatcaactttcagtcacagacatggaatatattgctgacacg atctttcctgctattggtaaaaatattatcagtaaaatggttaattttagccataaggta aaccaagaaataatagtagaaagaaaatggggtcaaaaaggaggaccatgggagtttaat ctacgtgacctcttccggtggtgtcaattaatgttagtagaccaaacagcagggtgctat gatccaggccagcatgttgctttggtatatgcagaccgaatgagaactgaagcagacagg agaaatatgtttgctgtatttgaaagaatattctcaaatggtgatgccaatcaattgtat ccctattcccagtccagaaaattccatatcaccccacagcagtttcaggttggttattct atcctttcacgtcatgcagtcagtgttcctatgtcgagcaaacgactgtcgattcttcac cattcacttcaaccactggagtcggttatgaagtgtgttcagatgaactggatgacaatt ttggtaggtccagctgccagtgggaaaaccagcctaatccagcttctcgctcttctgatg ggccaaaatttaaaggttatggcaatgaacagtgctatggacaccacagaactacttggt ggatttgagcaggttgatatattacgtccctggcaaagtttaattcggaaggtgaaggat tttgttcttgctgtcaccaagaatgttctcctctctctggactctttccatgatggcagt aatcttctcaaactctggaattcgttcctgaacagccattctcagtctcttgacaaggat catagatctggcatttcctctgaggcagtgaacaaactggagaatttgctcactgttctt caccagtgcaacaacaaattgaatacattctcgtcatcagaatttgaagaactcattgca gaattccagcaattcaatcacttacatagtcagtttttgaacggtgaaaagcgtggcact tttgaatgggtcgatgggatgcttgtacaggctttgatttcaggggattggctgctgctg gacaatgttaatttctgcagcccttctgtgcttgatcgtctgaatgctcttttggagcct ggaggagtcttgactattagtgaaagaggagtgattgatggcacctgcccaaccgttgtc ccacatccaaatttcagactgtttatgacaatggatccagtgcacggggaaatctctcgc gccatgaggaatcgtgggattgaaatttatattgcaggcgaacaaaattcagaacctttg gatgaacatgatatgaaaatgctgttacatgggcttggtcttatgggagaccatccatgt actgagctaatggcattgtattcagaaataaaagaaattgcagtagctggcatctccatc agttcattccttcgggcagctgtgcttattgttcagcagttgaagtgtggtcttgattta ccagaggcattcgttcgagcttgcttagaagtatttgcctcttcacagacttctcaagtt caccagaagcaagtacaagaattagtgaagaaacatggactcacattggcatcacctgaa ttccgggctcattccttgactattttagggctgtggccagattctgttccctcagcaatg ctaacagcagaggattcaatgctgtccatggtctatcgagatgggcaggtccttacttat tgtttgaaccaactgagccttaaaaataacaggtttcaaccgttgactctgactgacctg gaggtagttttgcagtcttgtaatatggaccatctttcattccatggcaattggacagca gctcaagtagccagtgaggttgatatgattcctactgctgtcagaatggtaacagagaaa gcgtctaatcaagattggctgttaagggctaggtggttgtgccatgttgcaaaatcccac aagcagttgccagacttggtgtttgcacaactggaagcggggtctcaaggtctcaatgca gtttattccagtgcactacctacaggaatgaaagacgttattcaacagctgcagcctaat gcaaaagacattgcctcagttcctttggatccacgatggaaccagcagcaattagtcatt ttgtttcattctgtgaattttgaaaatggggagcatcgtttgaaagagcttcaagcacag ctaagctctgttgctaacaggatggcatttctaatgaacagagaggaaagggtatatatg gagaagacaatcctggcatctgaagctacaaagaaatcaggaagacgcagtgctttgagg atatctatagcatttcataaagggatgctaagttttgaaaatctgcctcacccagccctg gcccatcttgctgctttctttgaaatctgggatgcttgtgtgctacagtgcataaaatct cagctttatcaccttgaagatgatgtcttcaatgaagtgctatgcaacgctgtgtggcga gatcggttctgggtggtttccgatagagtcactttggattccgaaggcatggcattgctc tcactccattggcattgggtcttgaaacaccttgtgaaggatcacctccaacagttgtct tgtgtttctcagatttctcaagaaattcacacagtttcagttaaccttcaaagtcatctt gctagcccaagtggaataacatttggtgtaaagaagatgcagaaatcactggggttccct cctccgttcaaggctgaatctgttgtggaatggacatctaaactcaagtcaataagttct gtcttggatgtgctcagtctgagaccaaaagtgacagacatagcctggaaagaccaactt tgtagaataaaagcagttaccactgattggaatatcaagaaggagttgctgttggcttgg ggtcttgtacttcgggcaaatcactttgcaggatttgacactgatgaaatacagcgtgta gtaaacactataacttccgtgatgaaatctcagggtcttctaaactcttctgattccaaa agtgttgagccaacaccacctcaactggatggggattgtttgaatcagctacaaagtaat attcagctgtggccagcagtggagtatttggcattgctttgcaagtttaaagttctggca gacctcttggatctatcattaatatctggaagcagaattaaacaagataagtcaaaaatc tgtgcagagctacgtcaattagtaacattttgcataagaacaactccaggcagtgcccga gctcttcaaggattttggtacttgatagagacagaacttcctgctgaagaattaaatttg ctgtgctcagaactgatttcatctgtatatggagcatgttggactagttcactgtcaaca gatcctgattattggctcacatggaaatcctctaagtctctagaaaatgatgggacactt gaagctttcacagacaaatccttaaaggggcctgctgttttatgtcaagcaatccaatca aaatgtttcttcgaggttctaattggtggtcaatataatcgtggggctattgagggaatt gttggggcagcagcatcccacgtctctctgggagagtggcaggaacggacgaagcagtta caagaaatcagcaccatattatggacaaacatggctgttaattcctttgcagagttcaga tttacagattcccgattgcagcgcattgttttacataaacagctccaggcagtgaagcat cttttgccaagagaaattcaggaggaatatttaaagacatgtgaccaacttgtctttgac aaggacgacacagcttgtgactctgttctgagttcgctcaaaggtctggcagggcatgga gtacttcctgaagacatagtttcactttttgtgacatgcatacaagaatttttgggtaaa gaaaaggattttgcaagcctttccaagcaggctcagagtggctgtctatgggtgtacctg gggttgctgcagattctgatttggacacctcagaccaagtttgatcctgctgttaaaaag atgtacaaactgaactatattaatgaggagttacaacaattggaaagcgaatggaagagc cggaatctgtcagaacatttatttacgggccgagaacactcacaagaaggagagaataag cattgccatccccgaattaggtttttgcagcagagaatcaaacagctgaaagaacgggcc acggtgctttccagaaaacaagcataccgtccaaatgtgccttcatacatatctctatac caggatatccatcactacatgttgagtattggccatggttccagaatcaaaacacttctc tttcgattgctgcaacatctgctggtgaagcgaccaaaaacaaggcagagcttccagacc atgttaaaggaagaggcggcttggcagcagtcccaacaccatttcaggaggcgaattgca gaagagtactggcagtatcctgatgtggtagagccacttaatgctgcagtcttgcaaatg caacatggcatgagacttctaacatctgaagttcatcttgcattaaatcataagtgtgtc aaccaagctgatctcacaaggttggtcacttgccttttggtcttcccttccatcagcttt gaattcccaacctactacagccttgcagaaacattatcttcaaagacctgcatagaaaca atacaaggacttgatgagctcttgagtaaaaacttgtcagccaaatctgaagagaagact ttgcttaaagagcaaagaacgctgctgacacaagaacagcttctgtttaatgcactacag tatctgcgttgccacatactctctgtgggtgaactggatcaggcttcgttgcagcttctc aggcacctctttcaagcaatggtaaatgcttgggatgagcaagaagaatgtagacgattg aaagaggagcaggaagctagcctctacaagtataagagtaagcagcatggcctttcggtg ttggaggaggaagaaaaggaattcagacagaatttcccacaatatagcaaggatttcact gatattacatctcagcccagtcttgaacaacaagagatggacactgaagttaagatcaca gaggctaaagcaaaacgtagtgcgcccatatcgccaggttccattgaaatgctcataaaa attcaccagcaaatatatctgggatgtgcccagtctatgtggtaccaccagggtgcacca gcacatcagagtagtgattaccttggtgcatttgtgtcctcttatcatacagcggcagtg ctaattacagaattctattctctcattgatgcttccatgagtggtcagcttcatggcagt cagttgctaatgagttccctcatccaaaatgctgtttctgaagaagggaactctgagctc accctgccccaggaggaaacctatgacttctatcaccatccaaatattctggaggtcaag aaatgtcagcctgttctgagaaatttgacccaaaaggtgaaagaattactgatagattgg cctgaccatccagccctgttgcagttgttggttgtaatggacagaattcgaggctttccc atctccagtcctctggcaaaattcttaagtggtatggagatcctcttgagcaaagcccag gattgggaacagaatgctagtcgctctgtctccttgcgagagcatcttgacgctatcacc cacctaattatccagtggaggaaattggagctaaattgctggaatgatagtcttgacatt gtgaggaaaagacagatggagaaatcatccaatcattggttttcattatatcagttggtt gaaaaataccttcagaagcaagcaggagaagatttgaaagaagtggctggtgggatgaca ctatcagaggtaatcaaaatactgcaagcttttattgaaggagctaccttggcagaattc catttccggttatcagtgctgctagcattccattgtcatgtattggtagtgccagagcag gagggaaaagatgccttatgcagtttactctggaatttgtacaactactacaagcaattt tcagagaccattgcctctaaaataactgaatgtcgtagcccgatagagaaagaattgaag gactacattagaatttgcagatggaatgatgtcagttactgggctgtaaagcagtcagtg gagaaagcgcacaggacattgtttaagttgatgaagaagtttgaaactgctctccaacag ccatgccgtcctgcattaacagagctgggaagaactggaagtttgggtagtgttgaccaa caaaaatggaccaagatagaaaagctaaattgtacactaaggaaagttttcacagaaaaa tgggattcaacacaggcaatttttcctaacttgggaaaaagcattctttataaagatgcg aattctcttcagactcacctgccagtactatgtaaaaggatgagaaaactgtgtttgaag ctggtgatgaaaagttcccttccaagattggtggaaagtctggatcagtttgcaggtgat gttatcactggagcacaagatctccaggctcttgcggttgatcagaatgctgataaggat gtacagaaatcagaagtcaaacatattttgatgcagaagcaaagggcattggcagacctc ttcaagcatcttgctgagatcggtctgtcttaccgcaaaggattggcttggtctcgaaca aaagatcttcaggacatgctgtgtctgcgcccacttgatgtgaaaacagcaataaacatg gttgaaagcagcgatgaattagataacatgctgctccaggaaattgctgctacatgggac ggatgtcagaagtatttctatcagtcccttgcacgacgggctgcactccagacagcatta cgtactcctacgaaagaactgagcctgggtacagttgagcgttgtcaaggatttactgct catctattgaaacttctgatcaaacaaagaaggcgacttactagactaactgagcagtgg gtcagcttgagacatctaattaagagtgtacaggaaattcagacaaggttggcaggattc aaggatcatgatgtggctcttccacctcagaatggcattaagctttggatggaccaactt cgcgcactcttcatgaaactcataataactttggaacaaactttgtggtttatgcaatgt tgtccaaaacaccagacagctgaagcacatcaggacatgcccattggaactcaaaaagtg gatagctgcgaaggagacctggaaagtaccagtgtggcaacagcatctttgcctgagaac tttgtccaatttcacctgacagtccctactccctttgtggccaatcactttcctgatgct tgtaatatgcagcaaggagatgcagcatggaaacaagtaaccagtcagattgcaaacgtg ttgaaagatgtcaaggtagcaaaggcagaaatggatgaaatgaaccatcaaacaaacaaa accttactttattcatggacatgttttgagacttgttcatcagggattggttgcttaagt agaacagttgttcatctgcaagatatacaggccatttttgctgttgctggttcccagagc acttgctgtccagtattattcagcagtctagaatacattaagaaggaagctagttgtgcg gtgactgaatttacaacatgggagaaagagctcctgaatctgacttttgatgattccagt gtggattcagaaatggatttctctccactggtggagccggttattaacacagtgctctgt gctgtgcagactgtattgaaagggcaaaaggaagaagctgaacaggaacaaggccaagtc atgggaaatgaaaatgaagatgaagcaaaagtgcgctctattccgactggatacttaagt gaagttttggagcatcaaatggcaaatgacatcagctccttaaacctcaagaaagttact gctgcagtttcagaccttctgaaaaagctcatagatcatcggcaggagtgcacaatagaa gagtaccagttgttcaatcaaaactgccgcagtattgtgcgattgcttcccatgttgact tcctactccgaactaatcctgtactacctgatggtttccatcacaactcataggagcact ggaaaattgctttccatcttgactcatttatttacagaccttgctatgcagggattctgc cttccaaaagagttgatggaggatgcaggaggtgaaggttcaacccaattccatgataat gagggtggagggattggagaaggtgaagggatgaaagacgttagcgacaagatagaaaaa gaagaccaggttgaagataccttctgcaaagaccaagaaaagaaagaggacccagaaaat atgccagatgttaaagatgaagaaaatgccatagaaatgtctgaggattttgatggaaag ctgcacgatggagagcccaaagaacaaggagagcaggataatgatgaagaatcagacagt gacgaagaagaagagctggataaacagatgggtgacctgggtgatgctgaagctgacaaa ttggatgaaagactttggggaggtgatgacgacgacgatgatgatgatgctagtgataag gctgaagaaactggaccagggatggatatggagcagtcggaactcgttgcgaaagatgac aatatggaagcagcaaatcaaaatgacagtgacacaaaaaaacaggaggaggaggagaaa aaagaaagagaggaaagcaaagacaaaatccatgaacagttggatgagcgagagtacgat gaaaatgaagtagacccttatcagggcaaacagaagcaaccagaagtagaagccttggat ctacccgatgatctcaatcttgaaaaccaagatggggataaaagtgaagatgagcatgag gaagaaggagacaatccatatgatatagaggaaaagttaatggatttcaacgaggtccct gcagacgaggaagaccagaaaatggaggagagttctgaacaagagaagactgaagatcac tctcaaactggtgatgaaactgaggagaaaaatcaaaaggaggatgatgaggaaaaaagt gaaaatccagatcaaaaactcccagaagaagaaacatctgaaaatttggaagaggaacag ttggcaaagcaggatgaacaaaacgaatctggcagggaggatacaggagtgcctgatgag ggtctgcagtcagaaacagacgacaatatggaagaccaggatgttcctgagtccaaacaa cgaatggagcacgaagctgcagggaaaactggagaggagaaccttcagagcgatacagct gtggaggtggcaggatctgcaactgagagagatcaggctaaggaggaacaagggtgtgga gctgcggatgctaatcagtcagaaggccatgaatccaaactgactgcaaggtttgcatct caaagacaatctcaggacaaaacacagagttacaaaagaaagcctggtcacgcagataat gagcgaacaatgggtgaccgcaatgaacgtgtgagtaagcgcctgaagacagtggaagct gacagtgcacaacagcaagacaccgctcagtcagaacaaggcgtcaaagaggcagacata tacgaacatgtgaaagagggatgtgattcctatgatactcaaacctatgatgcagccaca acagaacagcaaaaagtaggtggagcaggccaagaagagcaagatgaagattctgaatct attgaaatggaaaccattcaggaagaggaactggagtgtgtggacgtacaggaactgaag ccagagaaagaaaagtcttcaacttccacagcctcaggatatgacaacctggaagcagag ctgcaccctcccaaacctgaagatatcgatgatacaaaagatgactcgtcagactcggag aaagagttgtcaactgagaggagcagagagtccacaatccacactcgccatgaactgtta actgaggacatggaacaaagcacagtccctgacccggaagagctgcgtaaacagttagag gaacaactgagtgcgtggcaaaatgaagaggctggtgatccagaacaagagaaagctgca gctgcaatgtggcagcagtatcagacgttgaccgctcctctatcacagcagctgtgtgaa caacttcgccttatactggagcccacccaggcagctaaactcagaggggattatcgaact ggaaagcgattaaatatgcgcaaggtgattccttacatagccagtcagttccgtaaagat aaaatctggcttcgcaggacgaagccgagcaagcggcagtaccagatttgtttggctatt gatgactcctccagtatggttgacaaccattcgaaacagctggcctttgaagctttggct gtaattggaaatgctctctcacttctagaggttggacaggttgctgtgtgcagctttgga gagagcgttcagttgctgcacccgttccatgagcaattcagtgatcagtcaggagcacga atactgagaagctgtcaattccaacagaagaaaactaagatagcacagtttctggaatct gcagccaacatgtttgttgcagcacagcaccattcccaacaaggaaatccagaaattgct caattactattgattgtgtccgatggaagagggctgtttttagaggggaaagaacgagtt acaacagctgttcgagctgctcgacataacaatatttttgttatctttgttgtcctggac aatcctgattctaaggattccatcctggacatcaaggtccctattttcaagactccggga gaaatgccagaaattagatcatatatggaagaatttccgttcccattctatgtaatttta cgagatgtgaatgcactcccagagacactcagtgatgctctcaggcaatggtttgaactg gtgacagctgctgattattaa

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