Hemitrygon akajei (red stingray): 140733422
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Entry
140733422 CDS
T11019
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
haka Hemitrygon akajei (red stingray)
Pathway
haka00270
Cysteine and methionine metabolism
haka00480
Glutathione metabolism
haka01100
Metabolic pathways
haka01240
Biosynthesis of cofactors
haka04216
Ferroptosis
Module
haka_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
haka00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
140733422 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
140733422 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
140733422 (gclc)
Enzymes [BR:
haka01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
140733422 (gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
140733422
NCBI-ProteinID:
XP_072912830
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Position
9:105165710..105249865
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AA seq
637 aa
AA seq
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MGLLVEGSPLNWEETKKYADHVRKHGIIQFLNIYHKVKDRQKDVLKWGDEVEYMLLSFDH
EHQKVQVLLQGEEILHELQNRGEKANPNHPTLWRPEYGSYMIEGTPGQPYGGTMADFNTV
EANMKLRRQEVFALLKPNETISTITAFPRLGCHQFTKPVYEPKPIESGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKIAINVPIYKDKNVSSPFVEKFLNDDGEAARATKPDHIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPVVMALSAASPIYRGYVSDIDCRWGV
ISASVDDRTREERGLEPRKHSKYRISKSRYDSIDSYLSKCGEKYNDLELTVDDEIYKQLR
EGGIDHLLAQHIAHLFIRDPLTLYAERIHLDDANESDHFENIQSTNWQTMRFKPPPPNSE
IGWRVEFRPLEVQLTDFENSAYVVFVVLLTRVILSYKLDFLVPLSKVDENLIVAQKRDAV
RQGMFYFRKDIYKAGNPVVDGCACAQNGVDSDSEEYTLMSVDTIINGKEGVFPGLIPIIN
CYLENMEVDVDTRCSILNYLKLIRKRASGELMTAACWLRNFVAHHPDYKQDCIVTDKINY
DLIMKCDQIAKGLHDCPKLLGEVVSKPKHSDSKHSTV
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atgggtttactagtggagggatcgccactgaactgggaagagaccaaaaagtacgcggat
cacgtccgcaaacacggcatcatccagttcctcaacatctaccacaaggtgaaggaccga
cagaaggacgtgctgaaatggggcgatgaggttgagtatatgctgttgtcattcgatcac
gagcatcagaaagttcaggtactgcttcagggagaagaaattctccatgaactgcaaaat
cgaggagagaaggcaaatcccaaccacccaactctttggagacccgagtatggaagctac
atgattgaggggacacctgggcagccctatggagggaccatggcagattttaacactgta
gaagcaaatatgaagttgcgacgacaggaggtgtttgccttgttgaaaccaaatgagacc
atcagcaccattactgctttccccaggctcggatgtcaccaatttacaaaacctgtatat
gagccaaaaccaattgaaagtggagcctctaagtctctgttctttccagatgaagcaatt
aacaaacatccaagatttagcactttgactaggaacattcgtcacagaagaggagaaaaa
atagccattaatgtaccaatttataaagacaaaaatgtgtcttccccttttgttgagaag
tttctgaatgacgatggagaagctgcaagagcaacaaaacctgaccacatctatatggat
gcaatggggtttggaatgggcaattgttgccttcaggtgacattccaagcttgcagcatc
tcagaagccaggtatctttatgaccagcttgctacaatttgccctgttgtgatggctttg
agtgctgcttcaccaatctacagaggctatgtgtcagacatagattgtcgctggggtgta
atttctgcttctgtggatgatcgaaccagagaagaaagaggcttggagcctcgcaaacac
agcaaatacaggattagtaaatccaggtacgattccattgacagttacctctccaagtgt
ggggagaagtataacgatctggaattgaccgtggatgatgaaatctataagcaacttcga
gaaggaggtattgatcatctgctggcacaacatattgctcatcttttcattcgagatcct
ttaacgctctatgcagaaaggatacatttggacgatgccaatgaatctgatcactttgag
aatatacaatccacaaactggcaaacaatgagattcaagccaccacccccaaattctgaa
attggatggagggttgaatttcggccattggaggtccagttaacagacttcgagaattct
gcttatgtggtctttgttgtgctgctaaccagagtgatactttcctataaattagatttt
cttgttccactctcaaaagtggatgagaacctgattgtggctcaaaagcgcgatgctgtt
cgtcagggaatgttctacttcaggaaggacatctacaaagctggaaacccagttgttgat
ggctgtgcttgtgcacagaatggcgttgattcagattctgaggagtatacattaatgagc
gtagacactatcattaatggcaaggaaggagttttcccaggtttgattccaattataaac
tgttaccttgagaacatggaggtagatgttgatacgcggtgtagcattttaaactacctc
aagctgatccgaaagagagcttcaggagaactgatgactgcagcatgttggttaaggaac
tttgttgctcatcatcctgactacaagcaagactgtattgtgactgacaaaatcaactat
gacctaattatgaaatgtgaccaaattgcaaagggtttgcatgactgtccaaagctgctt
ggagaagtggtcagtaaaccgaaacattcggatagcaagcacagcactgtttaa
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