KEGG   Haliaeetus albicilla (white-tailed eagle): 104317813
Entry
104317813         CDS       T08398                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
hald  Haliaeetus albicilla (white-tailed eagle)
Pathway
hald00562  Inositol phosphate metabolism
hald01100  Metabolic pathways
hald04020  Calcium signaling pathway
hald04070  Phosphatidylinositol signaling system
hald04081  Hormone signaling
hald04082  Neuroactive ligand signaling
hald04261  Adrenergic signaling in cardiomyocytes
hald04270  Vascular smooth muscle contraction
hald04310  Wnt signaling pathway
hald04371  Apelin signaling pathway
hald04540  Gap junction
hald04621  NOD-like receptor signaling pathway
hald04912  GnRH signaling pathway
hald04916  Melanogenesis
Module
hald_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:hald00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    104317813 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    104317813 (PLCB2)
   04371 Apelin signaling pathway
    104317813 (PLCB2)
   04020 Calcium signaling pathway
    104317813 (PLCB2)
   04070 Phosphatidylinositol signaling system
    104317813 (PLCB2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    104317813 (PLCB2)
   04081 Hormone signaling
    104317813 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    104317813 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    104317813 (PLCB2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    104317813 (PLCB2)
   04916 Melanogenesis
    104317813 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    104317813 (PLCB2)
   04270 Vascular smooth muscle contraction
    104317813 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hald04131]
    104317813 (PLCB2)
Enzymes [BR:hald01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     104317813 (PLCB2)
Membrane trafficking [BR:hald04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    104317813 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    104317813 (PLCB2)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 104317813
NCBI-ProteinID: XP_009917092
LinkDB
Position
Unknown
AA seq 1208 aa
MSMLNPVLQPPEVKEYLSKGERFIRWDDETASASPVILRVDPKGFYLYWTYQNKEMEILD
ITSIRDTRVGRYAKIPKCQKLREVFNLDYPHSTFLLKTLTIVSGPDMVDLTFHNFVSYKE
NVGKSWAEDIMAIVRNPLTYNASRYTFLEKILVKLKMQLNAEGKIPVRNIFQMFPADRKR
VEAALTACHLPKGKNDAINPEDFPETVYKTFLMNLCPRPEIDEIFTSHHLKAKPYMTKEH
LAKFINKKQRDSRLNDILFPPAKPEQVQSLIEKYEPSGINIQRGQLSPEGMVWFLCGPEN
NVIALDKLQLYQDMTQPLSHYFINSSHNTYLTAGQFSGISSPEMYRQTLLAGCRCVELDC
WKGRPPDEEPIITHGFTMTTEILFKDAIEAIAESAFKTSLYPVILSFENHVDSPKQQAKM
AEYCRTIFGDMLLTEPLEKYPLKPGVPLPSPKDLLGKILIKNKKNQSISGKRQNSLKKGR
NVEPEIVEQPAPMDAEVWAGDVAEEEPEEEDVLLGNLDEEEIKKMQSDEGTAGLEVTAYE
EMSSLVNYIQPIKFDSFEVSAQKNRSYVISSFTELKAYDLLTKFPTKFVEYNKRQMSRIY
PKGTRMDSSNYMPQMFWNVGCQMVALNFQTMDVPMQQNMALFEFNGQCGYLLKHEFMRRP
DKQFDPFSVDRMDVVVASTLSVTILSGQFLSDRSVKTYVEVELFGLPRDTKRKYRTKLTS
TANSINPVWKEEAFVFEKIMMPELASLKIAAWEEGGKFIGHRVIPVIAVHSGYHHVCLRS
ESNMPLTMPSLFVYLEIKDYVPDAWADLTIALSNPIKFFSLQDKRSVQLKDASVERLGTQ
RNFPSAETNGIPDSTGKFSTPLSNGPAGAAAFAKDENVIEVMQIAEPQTASLVELQQMKL
FLKLLKKQEKELRELERKGSKRREELLQKYSVLFSDPVCYGCKKRMIHTRKTQKKRSLTT
GDVGTCANPVEMAESIDSRILELRERLEMDLIHLGEEHHDGIRRKKEQHATEQVTKIIEL
AREKQTAELKALKESSESNIKDIKKKLEAKRVDRIQTMMRNTSDKVAQERLKKEINNSHI
QEVVQTIKLVTQKTAMYQQKLEEKQADNLRTIKEKESQLQQEALAEYEEKLKTLNMEVQE
MVKNYAKPGFPGEPEMQKEAVQSVPEGEQGSTEQLKEKIPVAEVSRLTIAVPEPPGAETD
VEIEESIF
NT seq 3627 nt   +upstreamnt  +downstreamnt
atgtcaatgcttaaccctgtcctacagcccccagaggtgaaggagtatctatcgaagggt
gagcgcttcatcagatgggatgatgaaacagcaagtgcttctcctgtgattcttcgagtg
gatccaaagggattttacttatactggacgtatcagaataaggaaatggaaattttggat
ataaccagcatcagagatacccgagtggggcgatatgcaaaaatccccaagtgccagaag
ctccgagaggtttttaacttggattaccctcacagcaccttcctgcttaagactctgact
attgtatctggccctgacatggttgacctcactttccataactttgtgtcctacaaggag
aatgttggcaagagctgggctgaggatattatggccattgttcggaatcccctcacatac
aacgcttctcggtacaccttcctagagaaaatcctggtgaagctgaagatgcagcttaat
gcagaggggaaaattcctgtcaggaatatttttcagatgtttcctgcagacaggaagagg
gttgaagcagcattaaccgcttgtcatcttccaaagggcaagaatgatgccatcaaccca
gaggacttccctgagacagtgtataaaactttcctcatgaatctgtgtccacggcctgag
attgatgagatatttacctcacaccatttaaaagcaaagccctacatgaccaaagagcac
ttggcaaagtttatcaataagaagcagcgagactctcgcctcaatgacatcctcttccca
ccagccaaacctgagcaggtgcagagcctgatagagaagtatgagcccagtgggattaac
atccagagagggcagttgtctccagaggggatggtctggtttctctgtggccctgagaac
aatgtgatagcactggacaaattgcagctgtaccaggacatgacccagccactctcacac
tacttcatcaattcatcacacaacacatatttaacagctggtcagttttctgggatctca
tctcctgaaatgtatcgccagacactgctggctggctgccgctgcgtggagctggattgc
tggaagggtcgtcccccggatgaggagccaatcatcactcatgggttcaccatgacaact
gagatcctcttcaaggatgccattgaggccattgcagaaagtgcttttaaaacatctctc
taccctgtcatcctgtcctttgagaaccatgtggactcgcccaagcagcaggcaaagatg
gctgagtactgccgaaccatatttggagatatgctgctgacagagccgctggaaaaatac
ccactgaagccaggagttcctctgccaagtcctaaggatctcttagggaaaatcttgatt
aagaacaaaaagaaccaatctatatctgggaagaggcagaactctctgaagaaagggagg
aatgtggaaccagaaatcgtcgagcagccagcccctatggatgctgaagtctgggcaggt
gatgtggctgaagaggaaccagaggaagaggatgtacttcttggaaacctggatgaagag
gaaattaaaaagatgcagtcagatgagggcactgctggtttggaagtgacagcatacgag
gaaatgtccagcctagttaattacatacagcctatcaaatttgactcctttgaagtctct
gcccagaagaaccggagttatgtcatctcttccttcacagagctgaaggcttatgatcta
ctaaccaagttccctacaaagtttgtagaatacaacaagcgacagatgagccggatttac
cccaaaggcacccggatggactcctctaattacatgccccagatgttctggaatgtcggc
tgtcagatggtggcactgaacttccagaccatggatgtccctatgcagcagaacatggct
ctgtttgagttcaatggccagtgtggctatctgctcaagcatgaattcatgcggcgtcca
gacaagcagtttgaccccttctctgtggaccgcatggatgtggtggtggcaagtaccctg
tctgtcacgatactctctggtcagttcctctcagaccgcagtgtgaagacatatgtggaa
gtagagctgtttgggttgccaagggacacaaaacgcaaatacagaaccaaactgacctcc
actgctaattccattaaccctgtgtggaaagaggaggcttttgtttttgaaaagatcatg
atgcccgagttggcgtctctcaaaattgcggcttgggaggaaggagggaagttcattggt
catcgtgtcattcctgttattgcagtgcactcaggctatcaccatgtttgtctccgcagt
gaaagtaacatgccactcaccatgccttctctatttgtgtacctggaaataaaggactat
gttcctgatgcttgggcagatctgactattgctctctccaaccccattaagttcttcagt
ctgcaagacaaaagatcagttcagctaaaagatgcctcagtggagaggcttggcacacag
aggaacttcccatctgctgaaactaatgggataccagactccactgggaaattcagcact
cctctttctaatgggcctgcaggagcagcggcatttgccaaggacgaaaatgtgatagaa
gtgatgcagattgcagagcctcaaacagccagcctcgtagaactgcagcagatgaagctg
tttctgaagctgctgaagaaacaggagaaggaactgagggagttggagcggaaaggaagt
aaacggagggaggagctgctgcagaaatattctgtactcttttcagaccctgtctgctat
ggatgcaagaaaaggatgatacacactaggaagacacagaagaagaggagtttgacaaca
ggtgatgttggtacatgtgcaaatcctgtagaaatggctgaaagcatcgatagccgaatt
ttggaactgagagagaggctggagatggacctcatccacctgggagaggaacaccatgat
gggattcgaagaaagaaagaacagcatgcaacagagcaagttaccaagataatagagcta
gccagagagaagcagacagctgagctgaaggcactgaaggagtcatcagaaagcaacatt
aaagacattaagaagaagctggaggcaaagagagtggaccgaatccaaaccatgatgagg
aatacaagtgacaaggtggctcaggagaggttgaagaaagaaattaataactctcacatt
caggaagtggtgcaaacaatcaaactggtgacacaaaagacagccatgtatcagcagaaa
ctggaagagaagcaggcagacaatctgagaacaatcaaggagaaagaaagtcagctccag
caggaggcactggcagagtatgaggagaaattgaaaactctgaatatggaggtgcaggag
atggtgaagaactacgcgaaaccaggctttcctggagagcctgagatgcagaaggaagca
gttcagagtgttcctgagggagaacaagggtctacagaacaactgaaagagaagatccca
gtggcagaggtgtcaaggctcacaatagctgtgcctgagcccccaggagctgaaacagat
gtcgagatcgaagaaagcatattctga

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